TR200103288T2 - Tio-oksindol türevleri - Google Patents

Tio-oksindol türevleri

Info

Publication number
TR200103288T2
TR200103288T2 TR2001/03288T TR200103288T TR200103288T2 TR 200103288 T2 TR200103288 T2 TR 200103288T2 TR 2001/03288 T TR2001/03288 T TR 2001/03288T TR 200103288 T TR200103288 T TR 200103288T TR 200103288 T2 TR200103288 T2 TR 200103288T2
Authority
TR
Turkey
Prior art keywords
thio
oxindole derivatives
progesterone
compounds
adenocarcinomas
Prior art date
Application number
TR2001/03288T
Other languages
English (en)
Inventor
Fensome Adrew
Zhang Puwen
C. Koko Marci
E. Wrobel Jay
G. Melenski Edward
Zhi Lin
K. Jones Todd
M. Tegley Christopher
P. Edwards James
Original Assignee
American Home Products Corporation
Ligand Pharmaceuticals, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/552,033 external-priority patent/US6355648B1/en
Application filed by American Home Products Corporation, Ligand Pharmaceuticals, Inc. filed Critical American Home Products Corporation
Publication of TR200103288T2 publication Critical patent/TR200103288T2/tr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/40—Nitrogen atoms, not forming part of a nitro radical, e.g. isatin semicarbazone
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Indole Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

Bu bulus, sübstitüe gruplarinin yukarida tanimlandigi gibi oldugu (1) veya (2) genel yapilarina sahip olan projesteron reseptörü agonistleri olan bilesiklerle; veya bunlarin farmasötik olarak uygun bir tuzuyla, ve ayni zamanda bu bilesiklerin dogum kontrolü saglanmasinda veya projesteron ile ilgili karsinomalarin ve adenokarsinomalarin tedavisinde kullanim yöntemleri ile ilgilidir.
TR2001/03288T 1999-05-04 2000-05-01 Tio-oksindol türevleri TR200103288T2 (tr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17225999P 1999-05-04 1999-05-04
US09/552,033 US6355648B1 (en) 1999-05-04 2000-04-19 Thio-oxindole derivatives

Publications (1)

Publication Number Publication Date
TR200103288T2 true TR200103288T2 (tr) 2002-04-22

Family

ID=26867898

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2001/03288T TR200103288T2 (tr) 1999-05-04 2000-05-01 Tio-oksindol türevleri

Country Status (18)

Country Link
EP (1) EP1181275A1 (tr)
JP (1) JP2002543182A (tr)
KR (1) KR20020000636A (tr)
CN (1) CN1143847C (tr)
AU (1) AU767762B2 (tr)
BG (1) BG106078A (tr)
BR (1) BR0010216A (tr)
CA (1) CA2371633A1 (tr)
CZ (1) CZ20013950A3 (tr)
EA (1) EA005034B1 (tr)
GE (1) GEP20043266B (tr)
HU (1) HUP0200993A3 (tr)
MX (1) MXPA01011285A (tr)
NO (1) NO320912B1 (tr)
NZ (1) NZ515351A (tr)
PL (1) PL351407A1 (tr)
SK (1) SK15902001A3 (tr)
TR (1) TR200103288T2 (tr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4950027B2 (ja) * 2004-04-08 2012-06-13 ワイス・エルエルシー チオアミド不純物を最小限に抑えるための方法
JP4869221B2 (ja) * 2004-04-08 2012-02-08 ワイス・エルエルシー プロゲステロン受容体調節剤としてのチオアミド誘導体
GB201113538D0 (en) * 2011-08-04 2011-09-21 Karobio Ab Novel estrogen receptor ligands
WO2014058035A1 (en) * 2012-10-12 2014-04-17 Okinawa Institute Of Science And Technology School Corporation Novel spirooxindole derivative and process for producing the same
WO2016057931A1 (en) 2014-10-10 2016-04-14 The Research Foundation For The State University Of New York Trifluoromethoxylation of arenes via intramolecular trifluoromethoxy group migration
EP3519393B1 (en) * 2016-09-30 2022-05-18 Epizyme Inc Substituted fused bi- or tri- heterocyclic compounds as ehmt2 inhibitors

Also Published As

Publication number Publication date
BR0010216A (pt) 2002-03-19
SK15902001A3 (sk) 2002-11-06
BG106078A (en) 2002-05-31
EA005034B1 (ru) 2004-10-28
NO20015380D0 (no) 2001-11-02
MXPA01011285A (es) 2003-09-04
NO320912B1 (no) 2006-02-13
KR20020000636A (ko) 2002-01-05
AU4681400A (en) 2000-11-17
EA200101180A1 (ru) 2002-04-25
CA2371633A1 (en) 2000-11-09
AU767762B2 (en) 2003-11-20
CZ20013950A3 (cs) 2002-06-12
CN1143847C (zh) 2004-03-31
PL351407A1 (en) 2003-04-22
NO20015380L (no) 2002-01-03
NZ515351A (en) 2004-01-30
GEP20043266B (en) 2004-06-25
JP2002543182A (ja) 2002-12-17
CN1349499A (zh) 2002-05-15
EP1181275A1 (en) 2002-02-27
HUP0200993A3 (en) 2003-05-28
HUP0200993A2 (hu) 2002-07-29

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