EA004032B1 - Фармацевтические композиции лекарственных веществ с быстрым высвобождением - Google Patents

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Publication number

EA004032B1

EA004032B1 EA200100331A EA200100331A EA004032B1 EA 004032 B1 EA004032 B1 EA 004032B1 EA 200100331 A EA200100331 A EA 200100331A EA 200100331 A EA200100331 A EA 200100331A EA 004032 B1 EA004032 B1 EA 004032B1

Authority

EA

Eurasian Patent Office

Prior art keywords

composition

composition according

active substance

therapeutically

substance

Prior art date

1998-09-10

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• 229940088679 drug related substance Drugs 0.000 title claims abstract description 65
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• 238000000034 method Methods 0.000 claims abstract description 117
• 238000012360 testing method Methods 0.000 claims abstract description 107
• 239000013543 active substance Substances 0.000 claims abstract description 96
• 239000000126 substance Substances 0.000 claims abstract description 85
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• 239000008186 active pharmaceutical agent Substances 0.000 claims abstract description 58
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• VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 claims abstract description 47
• 239000012736 aqueous medium Substances 0.000 claims abstract description 45
• -1 e.g. Chemical compound 0.000 claims abstract description 35
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• VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 claims abstract description 24
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• QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 claims abstract description 10
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• HEFNNWSXXWATRW-JTQLQIEISA-N dexibuprofen Chemical compound CC(C)CC1=CC=C([C@H](C)C(O)=O)C=C1 HEFNNWSXXWATRW-JTQLQIEISA-N 0.000 claims abstract description 4
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