DOP2019000086A - Vectores de citomegalovirus que provocan células t restringidas por moléculas del complejo mayor de histocompatibilidad e - Google Patents

Vectores de citomegalovirus que provocan células t restringidas por moléculas del complejo mayor de histocompatibilidad e

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Publication number
DOP2019000086A
DOP2019000086A DO2019000086A DO2019000086A DOP2019000086A DO P2019000086 A DOP2019000086 A DO P2019000086A DO 2019000086 A DO2019000086 A DO 2019000086A DO 2019000086 A DO2019000086 A DO 2019000086A DO P2019000086 A DOP2019000086 A DO P2019000086A
Authority
DO
Dominican Republic
Prior art keywords
molecules
cause
major histocompatibility
histocompatibility complex
cells restricted
Prior art date
Application number
DO2019000086A
Other languages
English (en)
Spanish (es)
Inventor
Nelson Jay
Malouli Daniel
PICKER Louis
Hancock Meaghan
Sacha Johan
Frueh Klaus
Hansen Scott
Original Assignee
Univ Oregon Health & Science
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Oregon Health & Science filed Critical Univ Oregon Health & Science
Publication of DOP2019000086A publication Critical patent/DOP2019000086A/es

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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
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    • A61K40/46—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A61K48/0008—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'non-active' part of the composition delivered, e.g. wherein such 'non-active' part is not delivered simultaneously with the 'active' part of the composition
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
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    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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    • C12N2310/141—MicroRNAs, miRNAs
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    • C12N2710/16011—Herpesviridae
    • C12N2710/16111—Cytomegalovirus, e.g. human herpesvirus 5
    • C12N2710/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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    • C12N2710/16011—Herpesviridae
    • C12N2710/16111—Cytomegalovirus, e.g. human herpesvirus 5
    • C12N2710/16141—Use of virus, viral particle or viral elements as a vector
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    • C12N2710/16011—Herpesviridae
    • C12N2710/16111—Cytomegalovirus, e.g. human herpesvirus 5
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    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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DO2019000086A 2016-10-18 2019-04-08 Vectores de citomegalovirus que provocan células t restringidas por moléculas del complejo mayor de histocompatibilidad e DOP2019000086A (es)

Applications Claiming Priority (1)

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US201662409840P 2016-10-18 2016-10-18

Publications (1)

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DOP2019000086A true DOP2019000086A (es) 2019-07-31

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DO2019000086A DOP2019000086A (es) 2016-10-18 2019-04-08 Vectores de citomegalovirus que provocan células t restringidas por moléculas del complejo mayor de histocompatibilidad e

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US (2) US10532099B2 (OSRAM)
EP (1) EP3529363B1 (OSRAM)
JP (2) JP2019531745A (OSRAM)
KR (1) KR102604486B1 (OSRAM)
CN (1) CN110036112B (OSRAM)
AU (1) AU2017346788A1 (OSRAM)
BR (1) BR112019007982A2 (OSRAM)
CA (1) CA3040303A1 (OSRAM)
CL (1) CL2019001054A1 (OSRAM)
CO (1) CO2019004102A2 (OSRAM)
CR (1) CR20190205A (OSRAM)
DO (1) DOP2019000086A (OSRAM)
EA (1) EA201990937A1 (OSRAM)
EC (1) ECSP19031754A (OSRAM)
IL (1) IL266011B2 (OSRAM)
MA (1) MA46588A (OSRAM)
MX (1) MX2019004518A (OSRAM)
PE (1) PE20190840A1 (OSRAM)
SG (1) SG11201903340TA (OSRAM)
TN (1) TN2019000124A1 (OSRAM)
UA (1) UA126860C2 (OSRAM)
WO (1) WO2018075591A1 (OSRAM)

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