DOP2007000079A - Compuestos fenil amido heterocíclicos condensados - Google Patents

Compuestos fenil amido heterocíclicos condensados

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Publication number
DOP2007000079A
DOP2007000079A DO2007000079A DO2007000079A DOP2007000079A DO P2007000079 A DOP2007000079 A DO P2007000079A DO 2007000079 A DO2007000079 A DO 2007000079A DO 2007000079 A DO2007000079 A DO 2007000079A DO P2007000079 A DOP2007000079 A DO P2007000079A
Authority
DO
Dominican Republic
Prior art keywords
ring
formula
fenil
condensed heterocyclic
amido compounds
Prior art date
Application number
DO2007000079A
Other languages
English (en)
Inventor
Simon Bailey
Hao Bai
Dilip Ramakant Bhumralkar
Feng Bi
Fengli Guo
Mingying He
Paul Stuart Humphries
Anthony Lai Ling
Jihong Lou
Seiji Nukui
Ru Zhou
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of DOP2007000079A publication Critical patent/DOP2007000079A/es

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    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
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    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
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    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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    • A61P3/06Antihyperlipidemics
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    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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    • A61P31/06Antibacterial agents for tuberculosis
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    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07ORGANIC CHEMISTRY
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    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
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    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07DHETEROCYCLIC COMPOUNDS
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    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

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Abstract

La presente invención se refiere a un compuesto de fórmula (I): o una sal o solvato de éste aceptable desde un punto de vista farmacéutico, en el que: el anillo A es un heterociclilo de (4-12) miembros; el anillo B es un anillo de benceno condensado seleccionado entre el grupo que consiste en: el anillo A, el anillo B, el anillo C, R1, R1a, R2, R3, R4, L2, n, t, w, y z son como se han definido en la memoria descriptiva. La invención también se refiere a composiciones farmacéuticas que comprenden los compuestos de fórmula (I) y a métodos para tratar una afección que está mediada por la modulación de glucoquinasa, comprendiendo el método administrar a un mamífero una cantidad eficaz de un compuesto de fórmula (I). FORMULA:
DO2007000079A 2006-04-20 2007-04-19 Compuestos fenil amido heterocíclicos condensados DOP2007000079A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US79370306P 2006-04-20 2006-04-20

Publications (1)

Publication Number Publication Date
DOP2007000079A true DOP2007000079A (es) 2007-11-15

Family

ID=38283722

Family Applications (1)

Application Number Title Priority Date Filing Date
DO2007000079A DOP2007000079A (es) 2006-04-20 2007-04-19 Compuestos fenil amido heterocíclicos condensados

Country Status (17)

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EP (2) EP2463283B1 (es)
JP (1) JP5190448B2 (es)
AR (1) AR060533A1 (es)
CA (1) CA2648852C (es)
CL (1) CL2007001085A1 (es)
DK (1) DK2463283T3 (es)
DO (1) DOP2007000079A (es)
ES (1) ES2487967T3 (es)
GT (1) GT200700036A (es)
NL (1) NL2000581C2 (es)
PE (1) PE20080075A1 (es)
PL (1) PL2463283T3 (es)
PT (1) PT2463283E (es)
SI (1) SI2463283T1 (es)
TW (1) TW200808775A (es)
UY (1) UY30296A1 (es)
WO (1) WO2007122482A1 (es)

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