DOP2003000565A - Esteres hidroxamato del acido n-(4-fenil sustituido)- antranilico - Google Patents
Esteres hidroxamato del acido n-(4-fenil sustituido)- antranilicoInfo
- Publication number
- DOP2003000565A DOP2003000565A DO2003000565A DO2003000565A DOP2003000565A DO P2003000565 A DOP2003000565 A DO P2003000565A DO 2003000565 A DO2003000565 A DO 2003000565A DO 2003000565 A DO2003000565 A DO 2003000565A DO P2003000565 A DOP2003000565 A DO P2003000565A
- Authority
- DO
- Dominican Republic
- Prior art keywords
- substituted
- antranilico
- esteres
- hydroxamate
- phenyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/26—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C317/32—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
- C07C317/34—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having sulfone or sulfoxide groups and amino groups bound to carbon atoms of six-membered aromatic rings being part of the same non-condensed ring or of a condensed ring system containing that ring
- C07C317/36—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having sulfone or sulfoxide groups and amino groups bound to carbon atoms of six-membered aromatic rings being part of the same non-condensed ring or of a condensed ring system containing that ring with the nitrogen atoms of the amino groups bound to hydrogen atoms or to carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
- C07C259/04—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
- C07C259/10—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to carbon atoms of six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C323/31—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
- C07C323/33—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton having at least one of the nitrogen atoms bound to a carbon atom of the same non-condensed six-membered aromatic ring
- C07C323/35—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton having at least one of the nitrogen atoms bound to a carbon atom of the same non-condensed six-membered aromatic ring the thio group being a sulfide group
- C07C323/36—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton having at least one of the nitrogen atoms bound to a carbon atom of the same non-condensed six-membered aromatic ring the thio group being a sulfide group the sulfur atom of the sulfide group being further bound to an acyclic carbon atom
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Rheumatology (AREA)
- Neurosurgery (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Vascular Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Dermatology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
La presente invencion se refiere a esteres oxigenados de derivados del acido 4-sustituido-fenilamino-benzhidroxamico, a composiciones farmaceuticas y a metodos para su uso
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US35120102P | 2002-01-23 | 2002-01-23 |
Publications (1)
Publication Number | Publication Date |
---|---|
DOP2003000565A true DOP2003000565A (es) | 2003-08-15 |
Family
ID=27613472
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DO2003000565A DOP2003000565A (es) | 2002-01-23 | 2003-01-23 | Esteres hidroxamato del acido n-(4-fenil sustituido)- antranilico |
Country Status (15)
Country | Link |
---|---|
US (2) | US6891066B2 (es) |
EP (1) | EP1467968A1 (es) |
JP (1) | JP2005515253A (es) |
AR (1) | AR038213A1 (es) |
BR (1) | BR0307060A (es) |
CA (1) | CA2473545A1 (es) |
DO (1) | DOP2003000565A (es) |
GT (1) | GT200300010A (es) |
HN (1) | HN2003000044A (es) |
MX (1) | MXPA04005527A (es) |
PA (1) | PA8563801A1 (es) |
PE (1) | PE20030856A1 (es) |
TW (1) | TW592692B (es) |
UY (1) | UY27619A1 (es) |
WO (1) | WO2003062191A1 (es) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2549159T3 (es) | 2002-03-13 | 2015-10-23 | Array Biopharma, Inc. | Derivados de bencimidazol N3-alquilados como inhibidores de MEK |
AU2003220935A1 (en) * | 2002-04-03 | 2003-10-13 | Sumitomo Pharmaceuticals Company, Limited. | Benzamide derivatives |
AU2004283148A1 (en) | 2003-10-21 | 2005-05-06 | Warner-Lambert Company Llc | Polymorphic form of N-[(R)-2,3-Dihydroxy-propoxy]-3,4-difluoro-2-(2-fluoro-4-iodophenylamino)-benzamide |
DK1689233T3 (da) | 2003-11-19 | 2012-10-15 | Array Biopharma Inc | Bicykliske inhibitorer af MEK |
UA89035C2 (ru) * | 2003-12-03 | 2009-12-25 | Лео Фарма А/С | Эфиры гидроксамовых кислот и их фармацевтическое применение |
US20050171182A1 (en) * | 2003-12-11 | 2005-08-04 | Roger Briesewitz | Methods and compositions for use in the treatment of mutant receptor tyrosine kinase driven cellular proliferative diseases |
US8101799B2 (en) * | 2005-07-21 | 2012-01-24 | Ardea Biosciences | Derivatives of N-(arylamino) sulfonamides as inhibitors of MEK |
EA025871B9 (ru) | 2005-10-07 | 2017-08-31 | Экселиксис, Инк. | Ингибиторы mek и способы их применения |
WO2008076415A1 (en) | 2006-12-14 | 2008-06-26 | Exelixis, Inc. | Methods of using mek inhibitors |
US8993630B2 (en) | 2008-11-10 | 2015-03-31 | Bayer Intellectual Property Gmbh | Substituted sulphonamido phenoxybenzamides |
US9084781B2 (en) | 2008-12-10 | 2015-07-21 | Novartis Ag | MEK mutations conferring resistance to MEK inhibitors |
WO2011047055A2 (en) * | 2009-10-13 | 2011-04-21 | Allostem Therapeutics Llc | Novel mek inhibitors, useful in the treatment of diseases |
WO2011047788A1 (en) | 2009-10-21 | 2011-04-28 | Bayer Schering Pharma Aktiengesellschaft | Substituted benzosulphonamides |
WO2011047795A1 (en) | 2009-10-21 | 2011-04-28 | Bayer Schering Pharma Aktiengesellschaft | Substituted benzosulphonamides |
CN102574782B (zh) | 2009-10-21 | 2014-10-08 | 拜耳知识产权有限责任公司 | 取代的卤代苯氧基苯甲酰胺衍生物 |
EP3028699B1 (en) | 2010-02-25 | 2018-03-21 | Dana-Farber Cancer Institute, Inc. | Braf mutations conferring resistance to braf inhibitors |
ES2714875T3 (es) | 2010-03-09 | 2019-05-30 | Dana Farber Cancer Inst Inc | Métodos de diagnóstico y tratamiento del cáncer en pacientes que presentan o desarrollan resistencia a una primera terapia del cáncer |
CA2816188A1 (en) | 2010-10-29 | 2012-05-03 | Marion Hitchcock | Substituted phenoxypyridines |
WO2013169858A1 (en) | 2012-05-08 | 2013-11-14 | The Broad Institute, Inc. | Diagnostic and treatment methods in patients having or at risk of developing resistance to cancer therapy |
EP2854779A1 (en) | 2012-05-31 | 2015-04-08 | Bayer Pharma Aktiengesellschaft | Biomarkers for determining effective response of treatments of hepatocellular carcinoma (hcc) patients |
CR20200237A (es) | 2012-10-12 | 2020-07-26 | Exelixis Inc | Proceso novedoso para la elaboración de compuestos para su uso en el tratamiento del cáncer (diviisional 2015-0245) |
CA2889381C (en) | 2012-11-15 | 2023-01-03 | Duquesne University Of The Holy Ghost | Carboxylic acid ester prodrug inhibitors of mek |
JP6863742B2 (ja) * | 2013-09-11 | 2021-04-21 | ジ・アドミニストレーターズ・オブ・ザ・チューレーン・エデュケーショナル・ファンド | 新規アントラニルアミドとその使用 |
CN105646438A (zh) * | 2015-12-22 | 2016-06-08 | 天津大学 | 一种缩酮类糖醇基小分子凝胶因子及其制备方法和应用 |
US10214322B2 (en) * | 2016-02-16 | 2019-02-26 | Pan Pacific Plastics Mfg., Inc. | Child resistant plastic bag assembly |
LT3697405T (lt) | 2017-10-17 | 2021-10-25 | Atriva Therapeutics Gmbh | Naujas mek inhibitorius virusinėms ir bakterinėms infekcijoms gydyti |
TW202342018A (zh) | 2022-03-04 | 2023-11-01 | 美商奇奈特生物製藥公司 | Mek激酶抑制劑 |
Family Cites Families (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2082171A (en) | 1933-05-24 | 1937-06-01 | Winthrop Chem Co Inc | Basically substituted amino acridine derivatives |
NL62219C (es) | 1945-05-07 | |||
US2553914A (en) | 1948-03-22 | 1951-05-22 | Ward Blenkinsop & Co Ltd | Substituted diphenylamine 2-monocarboxylic acids and the production thereof |
US3781358A (en) | 1968-05-29 | 1973-12-25 | E Anderson | Intermediates for preparing acridines |
CH541608A (de) | 1970-11-06 | 1973-09-15 | Ciba Geigy Ag | Verfahren zur Herstellung von Nitrodiphenylaminen und deren Verwendung |
DE2636669A1 (de) * | 1976-08-14 | 1978-02-23 | Basf Ag | Verfahren zur herstellung von glykolestern |
US4121039A (en) * | 1977-09-26 | 1978-10-17 | Gaf Corporation | Process for producing an unsaturated glycol diester using a catalyst comprising palladium containing thorium as a promotor |
US4263448A (en) * | 1979-03-30 | 1981-04-21 | Halcon Research And Development Corp. | Process for oxidation of hydrocarbons |
US4510139A (en) | 1984-01-06 | 1985-04-09 | Sterling Drug Inc. | Substituted aminobenzamides and their use as agents which inhibit lipoxygenase activity |
DE3608726A1 (de) | 1986-03-15 | 1987-09-17 | Hoechst Ag | Verwendung aminosubstituierter benzoesaeuren als heilmittel gegen diarrhoe und arzneimittel auf basis dieser verbindungen |
US5155110A (en) | 1987-10-27 | 1992-10-13 | Warner-Lambert Company | Fenamic acid hydroxamate derivatives having cyclooxygenase and 5-lipoxygenase inhibition |
US5068250A (en) | 1988-09-29 | 1991-11-26 | Trustees Of University Of Pennsylvania | Irreversible ligands for nonsteroidal antiinflammatory drug and prostaglandin binding sites |
AU4090093A (en) | 1992-05-29 | 1993-12-30 | Yamanouchi Pharmaceutical Co., Ltd. | Medicine containing benzoic acid derivative and novel benzoic acid derivative |
US5525625A (en) | 1995-01-24 | 1996-06-11 | Warner-Lambert Company | 2-(2-Amino-3-methoxyphenyl)-4-oxo-4H-[1]benzopyran for treating proliferative disorders |
AU6858996A (en) | 1995-08-28 | 1997-03-19 | Interlab Corporation | Pharmaceutical compositions for the treatment of infectious diseases |
IL118657A0 (en) | 1996-06-14 | 1996-10-16 | Arad Dorit | Inhibitors for picornavirus proteases |
US6251943B1 (en) * | 1997-02-28 | 2001-06-26 | Warner-Lambert Company | Method of treating or preventing septic shock by administering a MEK inhibitor |
US6310060B1 (en) | 1998-06-24 | 2001-10-30 | Warner-Lambert Company | 2-(4-bromo or 4-iodo phenylamino) benzoic acid derivatives and their use as MEK inhibitors |
ES2229515T3 (es) * | 1997-07-01 | 2005-04-16 | Warner-Lambert Company Llc | Derivados 4-bromo o 4-yodo del acido fenilamino benzhidroxamico y su uso como inhibidores de la mek. |
EP0993437B1 (en) | 1997-07-01 | 2006-11-08 | Warner-Lambert Company Llc | 2-(4-bromo or 4-iodo phenylamino) benzoic acid derivatives and their use as mek inhibitors |
SI1028950T1 (en) | 1997-10-28 | 2003-08-31 | Warner-Lambert Company Llc | 7-substituted quinazolin-2,4-diones useful as antibacterial agents |
EP1150950A2 (en) | 1999-01-13 | 2001-11-07 | Warner-Lambert Company | Anthranilic acid derivatives |
CN1219753C (zh) | 2000-07-19 | 2005-09-21 | 沃尼尔·朗伯公司 | 4-碘苯氨基苯氧肟酸的氧合酯 |
-
2003
- 2003-01-13 CA CA002473545A patent/CA2473545A1/en not_active Abandoned
- 2003-01-13 JP JP2003562075A patent/JP2005515253A/ja not_active Withdrawn
- 2003-01-13 MX MXPA04005527A patent/MXPA04005527A/es unknown
- 2003-01-13 BR BR0307060-3A patent/BR0307060A/pt not_active IP Right Cessation
- 2003-01-13 EP EP03731797A patent/EP1467968A1/en not_active Withdrawn
- 2003-01-13 WO PCT/IB2003/000211 patent/WO2003062191A1/en active Application Filing
- 2003-01-17 PE PE2003000059A patent/PE20030856A1/es not_active Application Discontinuation
- 2003-01-22 TW TW092101396A patent/TW592692B/zh not_active IP Right Cessation
- 2003-01-22 GT GT200300010A patent/GT200300010A/es unknown
- 2003-01-22 AR ARP030100185A patent/AR038213A1/es unknown
- 2003-01-22 UY UY27619A patent/UY27619A1/es not_active Application Discontinuation
- 2003-01-23 DO DO2003000565A patent/DOP2003000565A/es unknown
- 2003-01-23 PA PA20038563801A patent/PA8563801A1/es unknown
- 2003-01-23 US US10/349,801 patent/US6891066B2/en not_active Expired - Fee Related
- 2003-01-27 HN HN2003000044A patent/HN2003000044A/es unknown
-
2005
- 2005-02-04 US US11/051,142 patent/US7078438B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
TW200302083A (en) | 2003-08-01 |
US20050137263A1 (en) | 2005-06-23 |
WO2003062191A8 (en) | 2004-01-15 |
AR038213A1 (es) | 2005-01-05 |
JP2005515253A (ja) | 2005-05-26 |
UY27619A1 (es) | 2003-08-29 |
PA8563801A1 (es) | 2003-09-17 |
TW592692B (en) | 2004-06-21 |
PE20030856A1 (es) | 2003-10-11 |
BR0307060A (pt) | 2004-10-26 |
CA2473545A1 (en) | 2003-07-31 |
HN2003000044A (es) | 2003-08-01 |
US6891066B2 (en) | 2005-05-10 |
EP1467968A1 (en) | 2004-10-20 |
GT200300010A (es) | 2003-08-22 |
US20040006245A1 (en) | 2004-01-08 |
WO2003062191A1 (en) | 2003-07-31 |
US7078438B2 (en) | 2006-07-18 |
MXPA04005527A (es) | 2005-03-23 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DOP2003000565A (es) | Esteres hidroxamato del acido n-(4-fenil sustituido)- antranilico | |
HN2003000038A (es) | Esteres hidroxamato de acido n-(4-fenil-sustituido)-antranilico | |
UY27659A1 (es) | Derivados de nicotinamida útiles como inhibidores de pde4 | |
AP2003002742A0 (en) | Oxygenated esters of 4-iodo phenylamino benzhydroxamic acids | |
PA8586001A1 (es) | Derivados de indol útiles para el tratamiento de enfermedades | |
DOP2001000224A (es) | Composiciones farmaceuticas de inhibidores de la proteina de transferencia de colesteril ester. | |
BRPI0408347B8 (pt) | derivados de pirimidina, seu uso, e composição e combinação farmacêuticas | |
SV2001000004A (es) | Difenil ureas w-carboxyaril sustituidas, composición farmacéutica que las comprende y su uso como inhibidores de raf quinasa | |
CR8649A (es) | Derivados de formamidina para el tratamiento de enfermedades | |
EE200100485A (et) | Uudsed ühendid ja kompositsioonid proteaasi inhibiitoritena | |
PA8632801A1 (es) | Derivados de tetrahidronaftiridina | |
PA8604301A1 (es) | Derivados de 2-amino-piridina utiles para el tratamiento de enfermedades | |
UY30748A1 (es) | Compuesto0s novedosos | |
PA8566601A1 (es) | Derivados de nicotinamida utiles como inhibidores de pde4 | |
CR7807A (es) | Piperacinil y diacepanil benzamidas y benztioamidas | |
PA8627001A1 (es) | Compuestos para el tratamiento de enfermedades | |
ECSP088229A (es) | Derivados de pirazolona como inhibidores de 11-beta hsd1 | |
PA8603001A1 (es) | Compuestos utiles para el tratamiento de enfermedades | |
ECSP055998A (es) | Composición farmacéutica que comprende ácido 5-metil-2-2'-(cloro-6'-fluoroanilino)fenilacético | |
UY30356A1 (es) | Derivados de 3-halo-n-(2.(4-fluorofenil)-4-oxobutil)-n-metil-5-(trifluorometil)benzamida y composiciones de los mismos. | |
SV2004001457A (es) | "sales estables del acido o-acetilsaliciclico con aminoacidos basicos ii" lea 35839-sv | |
AR063924A1 (es) | Analogos de pirazol | |
ITMI20031144A1 (it) | Analoghi del colchicoside. | |
CL2004000810A1 (es) | Compuesto derivado de acido hidroxamico de formula definida; composicion farmaceutica que comprende al compuesto y uso del compuesto para preparar medicamentos utiles para tratar trastornos hiperproliferativos. | |
DK1668003T3 (da) | Benzisoxazoler |