DK98886A - Antineoplastiske anthracyclin-midler indkapslet i micellulaere phospholipidpartikler og fremgangsmaader til deres anvendelse ved tumor-terapi - Google Patents

Antineoplastiske anthracyclin-midler indkapslet i micellulaere phospholipidpartikler og fremgangsmaader til deres anvendelse ved tumor-terapi Download PDF

Info

Publication number
DK98886A
DK98886A DK098886A DK98886A DK98886A DK 98886 A DK98886 A DK 98886A DK 098886 A DK098886 A DK 098886A DK 98886 A DK98886 A DK 98886A DK 98886 A DK98886 A DK 98886A
Authority
DK
Denmark
Prior art keywords
micellular
procedures
tumor therapy
agents included
particles
Prior art date
Application number
DK098886A
Other languages
English (en)
Other versions
DK175201B1 (da
DK98886D0 (da
Inventor
Eric Forssen
Original Assignee
Vestar Research Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25141806&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK98886(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Vestar Research Inc filed Critical Vestar Research Inc
Publication of DK98886D0 publication Critical patent/DK98886D0/da
Publication of DK98886A publication Critical patent/DK98886A/da
Application granted granted Critical
Publication of DK175201B1 publication Critical patent/DK175201B1/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Liposomes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • C07H15/24Condensed ring systems having three or more rings
    • C07H15/252Naphthacene radicals, e.g. daunomycins, adriamycins

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Dispersion Chemistry (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK198600988A 1985-10-15 1986-03-04 Kompositioner omfattende antineoplastiske anthracyclinmidler indkapslet i micellulære phospholipidpartikler og fremgangsmåder til fremstilling deraf DK175201B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US78753585A 1985-10-15 1985-10-15
US78753585 1985-10-15

Publications (3)

Publication Number Publication Date
DK98886D0 DK98886D0 (da) 1986-03-04
DK98886A true DK98886A (da) 1987-04-16
DK175201B1 DK175201B1 (da) 2004-07-05

Family

ID=25141806

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198600988A DK175201B1 (da) 1985-10-15 1986-03-04 Kompositioner omfattende antineoplastiske anthracyclinmidler indkapslet i micellulære phospholipidpartikler og fremgangsmåder til fremstilling deraf

Country Status (10)

Country Link
US (1) US4769250A (da)
EP (1) EP0219922B2 (da)
JP (1) JPH0761947B2 (da)
KR (1) KR890004689B1 (da)
AT (1) ATE65392T1 (da)
AU (1) AU587232B2 (da)
DE (1) DE3680447D1 (da)
DK (1) DK175201B1 (da)
IE (1) IE58981B1 (da)
NO (1) NO172729C (da)

Families Citing this family (56)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5435989A (en) * 1982-03-30 1995-07-25 Vestar, Inc. Method of targeting a specific location in a body
US5077056A (en) * 1984-08-08 1991-12-31 The Liposome Company, Inc. Encapsulation of antineoplastic agents in liposomes
US5736155A (en) * 1984-08-08 1998-04-07 The Liposome Company, Inc. Encapsulation of antineoplastic agents in liposomes
US5723147A (en) * 1987-02-23 1998-03-03 Depotech Corporation Multivesicular liposomes having a biologically active substance encapsulated therein in the presence of a hydrochloride
MX9203808A (es) * 1987-03-05 1992-07-01 Liposome Co Inc Formulaciones de alto contenido de medicamento: lipido, de agentes liposomicos-antineoplasticos.
US5811119A (en) * 1987-05-19 1998-09-22 Board Of Regents, The University Of Texas Formulation and use of carotenoids in treatment of cancer
US4863739A (en) * 1987-05-19 1989-09-05 Board Of Regents, The University Of Texas System Liposome compositions of anthracycline derivatives
JP2501336B2 (ja) * 1987-07-02 1996-05-29 第一製薬株式会社 安定なリポソ−ム製剤
FI874742A (fi) * 1987-10-28 1989-04-29 K & V Licencing Oy Foerfarande foer framstaellning av liposomer.
IE63518B1 (en) * 1987-11-18 1995-05-03 Vestar Inc Multiple step entrapment/loading procedure for preparing lipophilic drug-containing liposomes
US4946683A (en) * 1987-11-18 1990-08-07 Vestar, Inc. Multiple step entrapment/loading procedure for preparing lipophilic drug-containing liposomes
WO1989006654A1 (en) * 1988-01-19 1989-07-27 Board Of Regents, The University Of Texas System Glycosides, liposomal compositions thereof, and methods for their use
US5807572A (en) * 1988-02-18 1998-09-15 Depotech Corporation Multivesicular liposomes having a biologically active substance encapsulated therein in the presence of a hydrochloride
US5422120A (en) * 1988-05-30 1995-06-06 Depotech Corporation Heterovesicular liposomes
DE68916439T2 (de) * 1988-10-05 1994-10-20 Vestar Inc Verfahren zur herstellung von liposomen mit verbesserter stabilität während des trocknens.
US5013556A (en) * 1989-10-20 1991-05-07 Liposome Technology, Inc. Liposomes with enhanced circulation time
US20010051183A1 (en) * 1989-10-20 2001-12-13 Alza Corporation Liposomes with enhanced circulation time and method of treatment
CA2046997C (en) * 1990-07-16 2000-12-12 Hiroshi Kikuchi Liposomal products
US6060080A (en) * 1990-07-16 2000-05-09 Daiichi Pharmaceutical Co., Ltd. Liposomal products
DE4023241A1 (de) * 1990-07-21 1992-01-23 Knoll Ag Stabile wirkstoff-formulierung
AU660288B2 (en) * 1990-07-31 1995-06-22 Transave, Inc. Accumulation of amino acids and peptides into liposomes
JP2599492B2 (ja) * 1990-08-21 1997-04-09 第一製薬株式会社 リポソーム製剤の製造法
DK0592446T3 (da) * 1991-07-03 1996-01-29 Nexstar Pharmaceuticals Inc Fyldningsteknik til fremstilling af lægemiddelholdige liposomer
US5665381A (en) * 1992-02-25 1997-09-09 Nexstar Pharmaceuticals, Inc. Inhibition of aggregation of drug containing particles
BR9201168A (pt) * 1992-04-02 1994-04-12 Zerbini E J Fundacao Microemulsoes usadas como velculo para carregar quimioterapicos as celulas neoplasicas
US6093391A (en) * 1992-10-08 2000-07-25 Supratek Pharma, Inc. Peptide copolymer compositions
EP0619730B1 (en) * 1992-10-08 2000-12-27 Supratek Pharma Inc. Composition of antineoplastic agents incorporated in micelles
US5455044A (en) * 1993-05-14 1995-10-03 Depotech Corporation Method for treating neurological disorders
JP3002702B2 (ja) * 1993-11-16 2000-01-24 スカイファーム インコーポレーテッド 活性物質の制御放出を有する小胞
EP0664117A1 (de) * 1994-01-25 1995-07-26 F. Hoffmann-La Roche Ag Liposomenlösungen
US5714163A (en) * 1994-06-27 1998-02-03 Nexstar Pharmaceuticals, Inc. Vinca alkaloid vesicles with enhanced efficacy and tumor targeting properties
US5993850A (en) * 1994-09-13 1999-11-30 Skyepharma Inc. Preparation of multivesicular liposomes for controlled release of encapsulated biologically active substances
US20040208922A1 (en) * 1995-06-07 2004-10-21 The Regents Of The University Of California Method for loading lipid like vesicles with drugs or other chemicals
US5931809A (en) * 1995-07-14 1999-08-03 Depotech Corporation Epidural administration of therapeutic compounds with sustained rate of release
US6013278A (en) * 1996-05-14 2000-01-11 Burzynski Research Institute Liposomal antineoplaston therapies with markedly improved antineoplastic activity
US6060518A (en) * 1996-08-16 2000-05-09 Supratek Pharma Inc. Polymer compositions for chemotherapy and methods of treatment using the same
DE19639811A1 (de) * 1996-09-27 1998-04-02 Artur Herzog Dr Mesmer Verwendung einer Liposomenlösung zur Verstärkung der Wirksamkeit und/oder Verminderung der Toxizität von Arzneimitteln
US5997899A (en) 1996-10-01 1999-12-07 Skyepharma Inc. Method for producing liposomes with increased percent of compound encapsulated
WO1999002139A1 (en) * 1997-07-10 1999-01-21 Keith Baker Methods for universally distributing therapeutic agents to the brain
US6306432B1 (en) 1997-09-08 2001-10-23 Chiron Corporation High and low load formulations of IGF-I in multivesicular liposomes
CA2304096C (en) 1997-09-18 2003-09-09 Skyepharma Inc. Sustained-release liposomal anesthetic compositions
US6120800A (en) * 1997-09-25 2000-09-19 Nexstar Pharmaceuticals, Inc. Vinca-alkaloid vesicles with enhanced efficacy and tumor targeting properties
NZ504188A (en) 1997-11-14 2001-10-26 Skyepharma Inc Emulsification process for preparing multivesicular liposomes
AU5246900A (en) * 1999-06-14 2001-01-02 Japan Science And Technology Corporation Anticancer emulsions containing anthracycline compounds
EP1401396A4 (en) * 2001-06-15 2009-08-05 Cornerstone Pharmaceuticals PHARMACEUTICAL AND DIAGNOSTIC COMPOSITIONS WITH NANOPARTICLES FOR THE TREATMENT OF TARGET TISSUE AND CELLS
PL369545A1 (en) * 2001-09-28 2005-05-02 Esperion Therapeutics, Inc. Methods and apparatus for extrusion of vesicles at high pressure
AU2002340669A1 (en) * 2001-11-13 2003-05-26 Celator Technologies, Inc. Lipid carrier compositions with enhanced blood stability
US20030180348A1 (en) * 2002-03-22 2003-09-25 Levinson R. Saul Transcellular drug delivery system
US8980310B2 (en) * 2002-12-31 2015-03-17 Bharat Serums and Vaccines, Ltd. Non-pegylated long-circulating liposomes
GB2398495B (en) * 2003-01-23 2007-08-22 Kent G Lau A drug delivery preparation comprising at least one anti-tumour drug and a topical carrier for the drug
WO2007070705A2 (en) * 2005-12-15 2007-06-21 The Trustees Of The University Of Pennsylvania Cationic lipid-mediated vectors
BRPI0821100A2 (pt) * 2007-11-30 2017-05-23 Endo Pharmaceuticals Solutions composições e métodos para o tratamento de câncer de bexiga
US11980636B2 (en) 2020-11-18 2024-05-14 Jazz Pharmaceuticals Ireland Limited Treatment of hematological disorders
US11278494B1 (en) 2021-01-22 2022-03-22 Pacira Pharmaceuticals, Inc. Manufacturing of bupivacaine multivesicular liposomes
US11033495B1 (en) 2021-01-22 2021-06-15 Pacira Pharmaceuticals, Inc. Manufacturing of bupivacaine multivesicular liposomes
US11357727B1 (en) 2021-01-22 2022-06-14 Pacira Pharmaceuticals, Inc. Manufacturing of bupivacaine multivesicular liposomes

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1523965A (en) * 1976-03-19 1978-09-06 Ici Ltd Pharmaceutical compositions containing steroids
CH621479A5 (da) * 1977-08-05 1981-02-13 Battelle Memorial Institute
US4356167A (en) * 1978-01-27 1982-10-26 Sandoz, Inc. Liposome drug delivery systems
CA1173360A (en) * 1979-06-22 1984-08-28 Jurg Schrank Pharmaceutical preparations
US4310505A (en) * 1979-11-08 1982-01-12 California Institute Of Technology Lipid vesicles bearing carbohydrate surfaces as lymphatic directed vehicles for therapeutic and diagnostic substances
US4331654A (en) * 1980-06-13 1982-05-25 Eli Lilly And Company Magnetically-localizable, biodegradable lipid microspheres
JPS5793909A (en) * 1980-12-03 1982-06-11 Sankyo Co Ltd Carcinostatic pharmaceutical having directivity to specific internal organ and its preparation
US4419348A (en) * 1981-04-27 1983-12-06 Georgetown University Anthracycline glycoside compositions, their use and preparation
US4427664A (en) * 1981-05-29 1984-01-24 The United States Of America As Represented By The Department Of Health And Human Services 2'Halo derivatives of daunomycin, desmethoxy daunomycin, adriamycin and carminomycin
CA1187434A (en) * 1981-08-11 1985-05-21 Akihiro Yoshimoto Anthracycline antibiotics and their preparation method
EP0088046B1 (de) * 1982-02-17 1987-12-09 Ciba-Geigy Ag Lipide in wässriger Phase
US4438105A (en) * 1982-04-19 1984-03-20 Farmaitalia Carlo Erba S.P.A 4'-Iododerivatives of anthracycline glycosides
US4515736A (en) * 1983-05-12 1985-05-07 The Regents Of The University Of California Method for encapsulating materials into liposomes
EP0153955A1 (en) * 1983-09-06 1985-09-11 Health Research, Inc. Liposome delivery method for decreasing the toxicity of an antitumor drug
IL69720A (en) * 1983-09-14 1987-08-31 Univ Ramot Anti-tumor pharmaceutical compositions comprising liposome-bound porphyrins

Also Published As

Publication number Publication date
JPH0761947B2 (ja) 1995-07-05
AU5418486A (en) 1987-04-16
KR870003775A (ko) 1987-05-04
NO862193L (no) 1987-04-21
KR890004689B1 (ko) 1989-11-25
DK175201B1 (da) 2004-07-05
AU587232B2 (en) 1989-08-10
EP0219922A3 (en) 1987-10-28
EP0219922B2 (en) 2002-08-28
IE58981B1 (en) 1993-12-15
US4769250A (en) 1988-09-06
EP0219922A2 (en) 1987-04-29
NO172729C (no) 1993-09-01
DK98886D0 (da) 1986-03-04
EP0219922B1 (en) 1991-07-24
DE3680447D1 (de) 1991-08-29
JPS6287514A (ja) 1987-04-22
ATE65392T1 (de) 1991-08-15
NO862193D0 (no) 1986-06-03
IE860535L (en) 1987-04-15
NO172729B (no) 1993-05-24

Similar Documents

Publication Publication Date Title
DK98886D0 (da) Antineoplastiske anthracyclin-midler indkapslet i micellulaere phospholipidpartikler og fremgangsmaader til deres anvendelse ved tumor-terapi
GR1000074B (el) Λιποειδη σφαιριδια (κυστιδια) για ενδοπεριτονειακη χορηγηση θεραπευτικων παραγοντων.
Racker A new procedure for the reconstitution of biologically active phospholipid vesicles
HK115393A (en) Phospholipid particles encapsulating polyene antibiotics for the treatment of systemic fungal infections
GR1001503B (el) Μέ?οδος δια την παρασκευή φαρμακευτικών ενώσεων αι οποίαι περιέχουν ως δραστική ουσία καρβονικά οξέα τα οποία περιέχουν ?είον κα?ώς και η χρησιμοποίησις αυτών δια την καταπολέμησιν των ρετροιών.
DE3855265D1 (de) Liposomen-Formulierungen mit hohem antineoplastischem Wirkstoff/Lipid-Verhältnis
DK86988D0 (da) Liposompraeparat og anvendelse deraf
EP0151989A3 (en) Means for the treatment of cardiac diseases
DK524884D0 (da) Farmaceutiske praeparater indeholdende phosphatidylserin og fremgangsmaade til fremstilling deraf
CO4480019A1 (es) Liposomas de cetoprofeno
HUP0104665A2 (hu) Proantocianidin A2 foszfolipid-komplexek mint antiatheroszklerotikus ágensek
DK122190A (da) Phospholipid-indesluttet cationisk, lipofilt farmaceutisk praeparat og fremgangsmaade til fremstilling af samme
DK484685A (da) Micellulaere partikelkompositioner til maalrettet tilfoersel til tumorer i mennesker og kompositionernes anvendelse
DE3851842D1 (de) Wässrige bereitung von liposomenzusammensetzungen.
PT100155A (pt) Uso de compostos analogos da camptotecina na obtencao de um medicamento para uso no tratamento do carcinoma das celulas nao pequenas do pulmao e composicoes farmaceuticas
NO831951L (no) (+)-cyanidan-3-ol derivater, fremgangsmaater for deres fremstilling, farmasoeytiske preparater som inneholder slike forbindelser og deres anvendelse

Legal Events

Date Code Title Description
PUP Patent expired