CO4480019A1 - Liposomas de cetoprofeno - Google Patents

Liposomas de cetoprofeno

Info

Publication number
CO4480019A1
CO4480019A1 CO95046720A CO95046720A CO4480019A1 CO 4480019 A1 CO4480019 A1 CO 4480019A1 CO 95046720 A CO95046720 A CO 95046720A CO 95046720 A CO95046720 A CO 95046720A CO 4480019 A1 CO4480019 A1 CO 4480019A1
Authority
CO
Colombia
Prior art keywords
cetoprophen
amphyphils
ionic
iii
procedure
Prior art date
Application number
CO95046720A
Other languages
English (en)
Inventor
Silvana Ciceri
Hans-Jurgen Hamann
Ingrid Hurner
Peter Kurka
Joachim Maasz
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of CO4480019A1 publication Critical patent/CO4480019A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1277—Processes for preparing; Proliposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Rheumatology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Manufacturing Of Micro-Capsules (AREA)

Abstract

1. PROCEDIMIENTO PARA LA FABRICACION DE LIPOSOMAS DE CETOPROFENO, CARACTERIZADO PORQUE UNA MEZCLA DE CETOPROFENO Y FOSFOLIPIDOS O DE ANFIFILOS NO IONI- COS SE INTRODUCEN EN UNA SOLUCION CON UN VALOR pH DE 6 A 8 REDUCIENDOSE EL VALOR pH EN FORMACION ES- PONTANEA DE LIPOSOMAS QUE SE TRANSFORMAN, DADO EL CASO CON COADYUVANTES USUALES EN PREPARACIONES SE- MISOLIDAS Y LIQUIDAS. 2. PROCEDIMIENTO PARA LA FABRICACION DE LIPOSOMAS DE CETOPROFENO SEGUN LA REIVINDICACION 1, CARACTE- RIZADO PORQUE COMO ANFIFILOS NO IONICOS SE UTILI- ZAN COMPUESTOS DE LAS FORMULAS GENERALES (II) o (III) R4-O-(CH2-CH2-O)n H (II) Y R4-O-CH2-CH(-R5)-O-(CH2-CH2-O)n H (III) SIENDO R4 Y R5 IGUALES O DISTINTOS Y REPRESENTANDO RESPECTIVAMENTE ALQUILO O ALQUENILO CON 12 A 16 A- TOMOS C Y n UN NUMERO ENTRE 3 Y 25.
CO95046720A 1994-10-20 1995-10-06 Liposomas de cetoprofeno CO4480019A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI942142A IT1270678B (it) 1994-10-20 1994-10-20 Liposomi al chetoprofen

Publications (1)

Publication Number Publication Date
CO4480019A1 true CO4480019A1 (es) 1997-07-09

Family

ID=11369741

Family Applications (1)

Application Number Title Priority Date Filing Date
CO95046720A CO4480019A1 (es) 1994-10-20 1995-10-06 Liposomas de cetoprofeno

Country Status (14)

Country Link
US (1) US5741515A (es)
EP (1) EP0707847A1 (es)
JP (1) JPH08208466A (es)
KR (1) KR960013364A (es)
CN (1) CN1130060A (es)
AU (1) AU698915B2 (es)
BR (1) BR9504463A (es)
CA (1) CA2160739A1 (es)
CO (1) CO4480019A1 (es)
FI (1) FI954958A (es)
HU (1) HUT73531A (es)
IT (1) IT1270678B (es)
NO (1) NO954177L (es)
ZA (1) ZA958844B (es)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4447287C1 (de) * 1994-12-30 1996-11-07 Cevc Gregor Präparat zum Wirkstofftransport durch Barrieren
US20020048596A1 (en) * 1994-12-30 2002-04-25 Gregor Cevc Preparation for the transport of an active substance across barriers
DE19622224A1 (de) 1996-02-16 1997-08-21 Max Planck Gesellschaft Phosphatidyloligoglycerine
GB9625589D0 (en) 1996-12-10 1997-01-29 Boots Co Plc Therapeutic agents
CN1320880C (zh) 1998-12-23 2007-06-13 伊迪亚股份公司 改进的体内局部无创伤用制剂
SI1031347T1 (en) 1999-01-27 2002-10-31 Idea Ag Transnasal transport/immunisation with highly adaptable carriers
DK1031346T3 (da) 1999-01-27 2002-08-12 Idea Ag Ikke-invasiv vaccination gennem huden
US6844897B1 (en) * 1999-06-15 2005-01-18 Micron Technology, Inc. Active pixel sensor (APS) readout structure with amplification
AU5409699A (en) * 1999-07-05 2001-01-22 Idea Ag A method for the improvement of transport across adaptable semi-permeable barriers
US6610322B1 (en) 2000-12-20 2003-08-26 Brian Charles Keller Self forming, thermodynamically stable liposomes and their applications
US7268924B2 (en) * 2001-01-22 2007-09-11 Hand Held Products, Inc. Optical reader having reduced parameter determination delay
US7785623B2 (en) * 2002-10-01 2010-08-31 Keller Brian C Compositions and methods useful for the reduction of fine lines and wrinkles
US20040105881A1 (en) * 2002-10-11 2004-06-03 Gregor Cevc Aggregates with increased deformability, comprising at least three amphipats, for improved transport through semi-permeable barriers and for the non-invasive drug application in vivo, especially through the skin
WO2006050926A2 (en) * 2004-11-12 2006-05-18 Idea Ag Extended surface aggregates in the treatment of skin conditions
WO2007123993A2 (en) * 2006-04-19 2007-11-01 University Of South Florida Niosome-hydrogel drug delivery
US20100068264A1 (en) * 2006-07-12 2010-03-18 University Of South Florida Niosome-hydrogel drug delivery system
EA019992B1 (ru) 2009-03-12 2014-07-30 Лектио Фармаэнтвиклунгс-Унд Фервертунгс Гмбх Фармацевтическая композиция, включающая кетопрофен и полиоксиалкиленовый эфир жирной оксикислоты
US9522114B1 (en) 2014-03-27 2016-12-20 University Of South Florida Enhanced targeted drug delivery system via chitosan hydrogel and chlorotoxin

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1110989B (it) * 1979-01-19 1986-01-13 Erba Farmitalia Forme farmaceutiche costitutite da liposomi e procedimenti relativi
IL64397A0 (en) * 1981-01-07 1982-02-28 Weder Hans G Process for the preparation of liposomal medicaments
EP0088046B1 (de) * 1982-02-17 1987-12-09 Ciba-Geigy Ag Lipide in wässriger Phase
US4708861A (en) * 1984-02-15 1987-11-24 The Liposome Company, Inc. Liposome-gel compositions
US5008109A (en) * 1984-05-25 1991-04-16 Vestar, Inc. Vesicle stabilization
EP0249561B1 (en) * 1986-06-12 1992-05-13 The Liposome Company, Inc. Compositions using liposome-encapsulated non-steroidal anti-inflammatory drugs

Also Published As

Publication number Publication date
EP0707847A1 (de) 1996-04-24
HU9503015D0 (en) 1995-12-28
JPH08208466A (ja) 1996-08-13
IT1270678B (it) 1997-05-07
CN1130060A (zh) 1996-09-04
ITMI942142A1 (it) 1996-04-20
FI954958A (fi) 1996-04-21
FI954958A0 (fi) 1995-10-18
HUT73531A (en) 1996-08-28
NO954177D0 (no) 1995-10-19
AU698915B2 (en) 1998-11-12
ITMI942142A0 (it) 1994-10-20
BR9504463A (pt) 1997-05-20
US5741515A (en) 1998-04-21
ZA958844B (en) 1996-05-13
KR960013364A (ko) 1996-05-22
AU3427395A (en) 1996-05-02
NO954177L (no) 1996-04-22
CA2160739A1 (en) 1996-04-21

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