DK92486A - 1-0xa-1-dethiacephalosporinforbindelse - Google Patents

1-0xa-1-dethiacephalosporinforbindelse Download PDF

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Publication number
DK92486A
DK92486A DK92486A DK92486A DK92486A DK 92486 A DK92486 A DK 92486A DK 92486 A DK92486 A DK 92486A DK 92486 A DK92486 A DK 92486A DK 92486 A DK92486 A DK 92486A
Authority
DK
Denmark
Prior art keywords
sup
group
formula
ethyl
ring
Prior art date
Application number
DK92486A
Other languages
English (en)
Other versions
DK92486D0 (da
Inventor
Burton G Christensen
Seiji Shibahara
Tsuneo Okonogi
Yasushi Murai
Shunzo Fukatsu
Taro Niida
Jp Tadashi Wakazawa
Original Assignee
Merck & Co Inc
Meiji Seika Kaisha
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc, Meiji Seika Kaisha filed Critical Merck & Co Inc
Publication of DK92486D0 publication Critical patent/DK92486D0/da
Publication of DK92486A publication Critical patent/DK92486A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D505/00—Heterocyclic compounds containing 5-oxa-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D505/02—Preparation
    • C07D505/06—Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D505/00—Heterocyclic compounds containing 5-oxa-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D505/00—Heterocyclic compounds containing 5-oxa-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D505/10—Heterocyclic compounds containing 5-oxa-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D505/12—Heterocyclic compounds containing 5-oxa-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 substituted in position 7

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Cephalosporin Compounds (AREA)
DK92486A 1985-03-01 1986-02-28 1-0xa-1-dethiacephalosporinforbindelse DK92486A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/705,799 US4645769A (en) 1985-03-01 1985-03-01 1-oxa-1-dethia-cephalosporin compounds and antibacterial agent comprising the same

Publications (2)

Publication Number Publication Date
DK92486D0 DK92486D0 (da) 1986-02-28
DK92486A true DK92486A (da) 1986-09-02

Family

ID=24835001

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92486A DK92486A (da) 1985-03-01 1986-02-28 1-0xa-1-dethiacephalosporinforbindelse

Country Status (9)

Country Link
US (1) US4645769A (da)
EP (1) EP0193858B1 (da)
JP (1) JPH0633280B2 (da)
KR (1) KR900003500B1 (da)
AT (1) ATE69819T1 (da)
CA (1) CA1268177A (da)
DE (1) DE3682599D1 (da)
DK (1) DK92486A (da)
ES (2) ES8705450A1 (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK123488A (da) * 1987-03-09 1988-09-10 Otsuka Pharma Co Ltd 2-oxa-isocephemforbindelser, praeparater indeholdende dem, og fremgangsmaader til fremstilling af dem
DK582788A (da) * 1987-10-22 1989-04-23 Otsuka Pharma Co Ltd 2-oxa-isocephemforbindelser, midler der indeholder dem og fremgangsmaader til fremstilling af dem
US5525599A (en) * 1993-07-21 1996-06-11 Eli Lilly And Company 7-substituted-amino-3-substituted-3-cephem-4-carboxylic acids
JP6377570B2 (ja) * 2014-04-28 2018-08-22 グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドＧｌａｘｏｓｍｉｔｈｋｌｉｎｅ Ｉｎｔｅｌｌｅｃｔｕａｌ Ｐｒｏｐｅｒｔｙ Ｄｅｖｅｌｏｐｍｅｎｔ Ｌｉｍｉｔｅｄ ２−置換セフェム化合物を含有する医薬組成物

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4226866A (en) * 1972-11-06 1980-10-07 Merck & Co., Inc. Novel antibiotic analogues of cephalosporins
JPS5331690A (en) * 1976-09-01 1978-03-25 Shionogi & Co Ltd Oxadithiacephalosporins
GB1557552A (en) * 1977-02-15 1979-12-12 Shionogi & Co 1 oxadethiacepham compounds
DE2714880A1 (de) * 1977-04-02 1978-10-26 Hoechst Ag Cephemderivate und verfahren zu ihrer herstellung
CH649557A5 (de) * 1978-11-17 1985-05-31 Glaxo Group Ltd Cephalosporinantibiotika.
BE883415A (fr) * 1979-05-23 1980-11-21 Rhone Poulenc Ind Nouvelles thiovinyl-3 cephalosporines, leur preparation et les compositions qui les contiennent
FR2474504A1 (fr) * 1979-05-23 1981-07-31 Rhone Poulenc Ind Nouvelles thiovinyl-3 cephalosporines, leur preparation et les medicaments qui les contiennent
DE3137038A1 (de) * 1981-09-17 1983-03-24 Bayer Ag, 5090 Leverkusen Ss-lactam antibiotika, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
JPS5849382A (ja) * 1981-09-18 1983-03-23 Kyowa Hakko Kogyo Co Ltd β−ラクタム化合物
JPS5874680A (ja) * 1981-10-01 1983-05-06 Kyowa Hakko Kogyo Co Ltd β−ラクタム化合物
FR2516515A1 (fr) * 1981-11-16 1983-05-20 Sanofi Sa Nouveaux derives de pyridinium thiomethyl cephalosporines, procede pour leur preparation et compositions pharmaceutiques les contenant
US4534898A (en) * 1982-07-23 1985-08-13 Merck & Co., Inc. 1-Oxa-1-dethia-cephalosporin derivatives

Also Published As

Publication number Publication date
ES557155A0 (es) 1987-08-16
JPH0633280B2 (ja) 1994-05-02
ATE69819T1 (de) 1991-12-15
US4645769A (en) 1987-02-24
JPS61251685A (ja) 1986-11-08
CA1268177A (en) 1990-04-24
ES552486A0 (es) 1987-05-01
EP0193858B1 (en) 1991-11-27
ES8707726A1 (es) 1987-08-16
DE3682599D1 (de) 1992-01-09
KR900003500B1 (ko) 1990-05-21
KR860007264A (ko) 1986-10-10
DK92486D0 (da) 1986-02-28
ES8705450A1 (es) 1987-05-01
EP0193858A1 (en) 1986-09-10

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment