DK75091D0 - Immunogent aktive fraktioner af borrelia burgdor feri - Google Patents

Immunogent aktive fraktioner af borrelia burgdor feri

Info

Publication number
DK75091D0
DK75091D0 DK91750A DK75091A DK75091D0 DK 75091 D0 DK75091 D0 DK 75091D0 DK 91750 A DK91750 A DK 91750A DK 75091 A DK75091 A DK 75091A DK 75091 D0 DK75091 D0 DK 75091D0
Authority
DK
Denmark
Prior art keywords
pellet
supernatant
fraction
components
new
Prior art date
Application number
DK91750A
Other languages
English (en)
Other versions
DK75091A (da
DK175844B1 (da
Inventor
Sven Bergstroem
Alan G Barbour
Louis A Magnarelli
Original Assignee
Symbicom Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Symbicom Ab filed Critical Symbicom Ab
Priority to DK199100750A priority Critical patent/DK175844B1/da
Publication of DK75091D0 publication Critical patent/DK75091D0/da
Publication of DK75091A publication Critical patent/DK75091A/da
Priority to DK200401413A priority patent/DK200401413A/da
Application granted granted Critical
Publication of DK175844B1 publication Critical patent/DK175844B1/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1203—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
    • C07K16/1207—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Spirochaetales (O), e.g. Treponema, Leptospira
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/20—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Spirochaetales (O), e.g. Treponema, Leptospira
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/035—Fusion polypeptide containing a localisation/targetting motif containing a signal for targeting to the external surface of a cell, e.g. to the outer membrane of Gram negative bacteria, GPI- anchored eukaryote proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK199100750A 1988-10-24 1991-04-23 DNA fragment, der koder for et Borrelia burgdorferi OspA polypeptid, en vektor, en værtsmikroorganisme, en fremgangsmåde til fremstilling af OspA polypeptider samt en fremgangsmåde til diagnosticering af Borrelia burgdorferi infektion DK175844B1 (da)

Priority Applications (2)

Application Number Priority Date Filing Date Title
DK199100750A DK175844B1 (da) 1988-10-24 1991-04-23 DNA fragment, der koder for et Borrelia burgdorferi OspA polypeptid, en vektor, en værtsmikroorganisme, en fremgangsmåde til fremstilling af OspA polypeptider samt en fremgangsmåde til diagnosticering af Borrelia burgdorferi infektion
DK200401413A DK200401413A (da) 1988-10-24 2004-09-17 OspA polypeptid, præparat omfattende OspA polypeptidet og anvendelse af OspA polypeptidet til fremstilling af et præparat til immunisering mod Lyme Disease

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DK590288A DK590288D0 (da) 1988-10-24 1988-10-24 Kemiske forbindelser
PCT/DK1989/000248 WO1990004411A1 (en) 1988-10-24 1989-10-24 Immunogenically active fractions of borrelia burgdorferi
DK199100750A DK175844B1 (da) 1988-10-24 1991-04-23 DNA fragment, der koder for et Borrelia burgdorferi OspA polypeptid, en vektor, en værtsmikroorganisme, en fremgangsmåde til fremstilling af OspA polypeptider samt en fremgangsmåde til diagnosticering af Borrelia burgdorferi infektion

Publications (3)

Publication Number Publication Date
DK75091D0 true DK75091D0 (da) 1991-04-23
DK75091A DK75091A (da) 1991-06-12
DK175844B1 DK175844B1 (da) 2005-03-29

Family

ID=8146053

Family Applications (3)

Application Number Title Priority Date Filing Date
DK590288A DK590288D0 (da) 1919-10-24 1988-10-24 Kemiske forbindelser
DK199100750A DK175844B1 (da) 1988-10-24 1991-04-23 DNA fragment, der koder for et Borrelia burgdorferi OspA polypeptid, en vektor, en værtsmikroorganisme, en fremgangsmåde til fremstilling af OspA polypeptider samt en fremgangsmåde til diagnosticering af Borrelia burgdorferi infektion
DK200401413A DK200401413A (da) 1988-10-24 2004-09-17 OspA polypeptid, præparat omfattende OspA polypeptidet og anvendelse af OspA polypeptidet til fremstilling af et præparat til immunisering mod Lyme Disease

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK590288A DK590288D0 (da) 1919-10-24 1988-10-24 Kemiske forbindelser

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK200401413A DK200401413A (da) 1988-10-24 2004-09-17 OspA polypeptid, præparat omfattende OspA polypeptidet og anvendelse af OspA polypeptidet til fremstilling af et præparat til immunisering mod Lyme Disease

Country Status (10)

Country Link
US (6) US5523089A (da)
EP (4) EP0445135B1 (da)
AT (3) ATE432988T1 (da)
AU (1) AU639667B2 (da)
CA (1) CA2001328C (da)
DE (4) DE68929565D1 (da)
DK (3) DK590288D0 (da)
FI (1) FI112366B (da)
NO (1) NO911602L (da)
WO (1) WO1990004411A1 (da)

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US6143872A (en) * 1988-10-24 2000-11-07 Symbicom Aktiebolag Borrelia burdorferi Osp A and B proteins and immunogenic peptides
US6300101B1 (en) * 1988-10-24 2001-10-09 Board Of Regents, The University Of Texas System Methods and compositions including a 13kD B. burgdorferi protein
US7094391B1 (en) * 1988-10-24 2006-08-22 The University Of Texas System Compositions and methods for administering Borrelia burgdorferi antigens
US5777095A (en) * 1988-10-24 1998-07-07 Symbicom Aktiebolag Osp A and B Sequence of Borrelia burgdonferi strains ACA1 and IP90
ZA907419B (en) * 1989-09-19 1991-07-31 Max Planck Gesellschaft Vaccine against lyme disease
DE4015911A1 (de) * 1989-09-19 1991-03-28 Max Planck Gesellschaft Impfstoff gegen die lyme-krankheit
US5470712A (en) * 1990-03-05 1995-11-28 Us Health Antigenic proteins of Borrelia burgdorferi
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EP1016416A3 (en) * 1990-07-06 2002-10-23 Wyeth Vaccine against lyme disease and a challenge model for evaluating vaccine efficacy
CA2057536C (en) * 1990-12-21 1999-10-26 John J. Dunn Cloning and expression of borrelia lipoproteins
US5436000A (en) * 1991-01-11 1995-07-25 University Of Texas System Flagella-less borrelia
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US5324630A (en) * 1991-06-28 1994-06-28 The Regents Of The University Of California Methods and compositions for diagnosing lyme disease
US6221363B1 (en) * 1991-07-11 2001-04-24 Baxter Aktiengesellschaft Vaccine for the prevention of lyme disease
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ATE234365T1 (de) * 1991-10-22 2003-03-15 Symbicom Ab Verbesserungen der diagnose und der prophylaxe von borrelia burgdorferi
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US6248562B1 (en) 1993-11-01 2001-06-19 Research Foundation State University Of New York Chimeric proteins comprising borrelia polypeptides and uses therefor
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US4683195A (en) * 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4981685A (en) * 1986-03-07 1991-01-01 Utah State University Foundation Bacterial extract vaccines for veterinary application
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Also Published As

Publication number Publication date
US6203798B1 (en) 2001-03-20
EP1092774A2 (en) 2001-04-18
EP1092774B1 (en) 2009-06-03
ATE432988T1 (de) 2009-06-15
DE68929369T2 (de) 2002-09-26
DE68927891T2 (de) 1997-10-02
FI911964A0 (fi) 1991-04-23
DK200401413A (da) 2004-09-17
DK75091A (da) 1991-06-12
DK590288D0 (da) 1988-10-24
ATE212376T1 (de) 2002-02-15
NO911602D0 (no) 1991-04-23
EP0445135A1 (en) 1991-09-11
DE68927891D1 (de) 1997-04-24
DK175844B1 (da) 2005-03-29
DE68929369D1 (de) 2002-03-14
US5688512A (en) 1997-11-18
EP0565208A1 (en) 1993-10-13
EP0711563B1 (en) 2007-01-17
FI112366B (fi) 2003-11-28
US5523089A (en) 1996-06-04
US6083722A (en) 2000-07-04
US6183986B1 (en) 2001-02-06
CA2001328A1 (en) 1991-04-24
WO1990004411A1 (en) 1990-05-03
ATE150318T1 (de) 1997-04-15
DE68929565D1 (de) 2009-07-16
US5582990A (en) 1996-12-10
NO911602L (no) 1991-06-24
DE68929550T2 (de) 2007-12-06
AU639667B2 (en) 1993-08-05
DE68929550D1 (de) 2007-03-08
AU4495389A (en) 1990-05-14
CA2001328C (en) 2005-12-13
EP0445135B1 (en) 1997-03-19
EP1092774A3 (en) 2001-04-25
EP0565208B1 (en) 2002-01-23
EP0711563A1 (en) 1996-05-15

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