DK624989A - Makrolidforbindelser - Google Patents

Makrolidforbindelser Download PDF

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Publication number
DK624989A
DK624989A DK624989A DK624989A DK624989A DK 624989 A DK624989 A DK 624989A DK 624989 A DK624989 A DK 624989A DK 624989 A DK624989 A DK 624989A DK 624989 A DK624989 A DK 624989A
Authority
DK
Denmark
Prior art keywords
hydrogen
macrolide
ch2oh
chem
alkyl
Prior art date
Application number
DK624989A
Other languages
Danish (da)
English (en)
Other versions
DK624989D0 (da
Inventor
Michael John Driver
William Skinner Maclachlan
Andrew William Taylor
Original Assignee
Beecham Group Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group Plc filed Critical Beecham Group Plc
Publication of DK624989D0 publication Critical patent/DK624989D0/da
Publication of DK624989A publication Critical patent/DK624989A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C07H15/08—Polyoxyalkylene derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Mechanical Treatment Of Semiconductor (AREA)
  • Furan Compounds (AREA)
  • Devices For Conveying Motion By Means Of Endless Flexible Members (AREA)
DK624989A 1988-12-19 1989-12-11 Makrolidforbindelser DK624989A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB888829593A GB8829593D0 (en) 1988-12-19 1988-12-19 Novel compounds

Publications (2)

Publication Number Publication Date
DK624989D0 DK624989D0 (da) 1989-12-11
DK624989A true DK624989A (da) 1990-06-20

Family

ID=10648737

Family Applications (1)

Application Number Title Priority Date Filing Date
DK624989A DK624989A (da) 1988-12-19 1989-12-11 Makrolidforbindelser

Country Status (15)

Country Link
US (1) US5100876A (ja)
EP (1) EP0375222B1 (ja)
JP (1) JPH02207093A (ja)
KR (1) KR900009677A (ja)
AT (1) ATE119910T1 (ja)
AU (1) AU614204B2 (ja)
CA (1) CA2005134A1 (ja)
DE (1) DE68921719T2 (ja)
DK (1) DK624989A (ja)
ES (1) ES2071667T3 (ja)
GB (1) GB8829593D0 (ja)
IE (1) IE893956L (ja)
NZ (1) NZ231722A (ja)
PT (1) PT92540B (ja)
ZA (1) ZA899506B (ja)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0350164A3 (en) * 1988-06-13 1991-07-24 Beecham Group Plc Amphotericin derivatives
GB8829592D0 (en) * 1988-12-19 1989-02-08 Beecham Group Plc Novel compounds
AU6951491A (en) * 1989-12-08 1991-07-18 Beecham Group Plc Amphotericin b derivatives, their production and use
GB9114949D0 (en) * 1991-07-11 1991-08-28 Smithkline Beecham Plc Novel compounds
FR2683723B1 (fr) * 1991-11-14 1995-05-19 Mayoly Spindler Laboratoires Nouveaux medicaments antiviraux actifs sur le virus vih.
GB9200713D0 (en) * 1992-01-14 1992-03-11 Smithkline Beecham Plc Novel compounds
WO2001051061A1 (en) 2000-01-14 2001-07-19 Intrabiotics Pharmaceuticals, Inc. Derivatives of polyene macrolides and preparation and use thereof
US9447136B2 (en) 2012-03-09 2016-09-20 Blirt S.A. Semisynthetic derivatives of Nystatin A1
WO2013186384A1 (en) 2012-06-15 2013-12-19 Blirt S.A. N-substituted second generation derivatives of antifungal antibiotic amphotericin b and methods of their preparation and application
WO2015190587A1 (ja) 2014-06-12 2015-12-17 塩野義製薬株式会社 ポリエンマクロライド誘導体

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2173632A1 (en) * 1971-02-04 1973-10-12 Le N Iss Purificn of amfotericin b - in dmf soln by adding water acidifying filtering adding water,making alkaline and washing
US4223130A (en) * 1978-09-28 1980-09-16 Schering Corporation Antibiotic 67-121, a polyene antifungal antibiotic produced by Actinoplanes caeruleus
US4235993A (en) * 1979-02-21 1980-11-25 E. R. Squibb & Sons, Inc. N-Benzylideneamphotericin B, its methyl ester and process for making water-soluble salts thereof
EP0350164A3 (en) * 1988-06-13 1991-07-24 Beecham Group Plc Amphotericin derivatives
GB8829592D0 (en) * 1988-12-19 1989-02-08 Beecham Group Plc Novel compounds

Also Published As

Publication number Publication date
GB8829593D0 (en) 1989-02-08
ZA899506B (en) 1991-08-28
CA2005134A1 (en) 1990-06-19
DE68921719T2 (de) 1995-07-13
NZ231722A (en) 1992-04-28
JPH02207093A (ja) 1990-08-16
DK624989D0 (da) 1989-12-11
EP0375222A3 (en) 1991-05-29
PT92540B (pt) 1995-08-09
DE68921719D1 (de) 1995-04-20
US5100876A (en) 1992-03-31
KR900009677A (ko) 1990-07-05
PT92540A (pt) 1990-06-29
ES2071667T3 (es) 1995-07-01
EP0375222B1 (en) 1995-03-15
IE893956L (en) 1990-06-19
ATE119910T1 (de) 1995-04-15
EP0375222A2 (en) 1990-06-27
AU4617089A (en) 1990-06-21
AU614204B2 (en) 1991-08-22

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment