DK593886A - Forbindelser og farmaceutiske praeparater der inhiberer 5-lipoxygenase-vejen - Google Patents

Forbindelser og farmaceutiske praeparater der inhiberer 5-lipoxygenase-vejen

Info

Publication number
DK593886A
DK593886A DK593886A DK593886A DK593886A DK 593886 A DK593886 A DK 593886A DK 593886 A DK593886 A DK 593886A DK 593886 A DK593886 A DK 593886A DK 593886 A DK593886 A DK 593886A
Authority
DK
Denmark
Prior art keywords
lipoxygenase
road
compounds
pharmaceutical preparations
inhibiting
Prior art date
Application number
DK593886A
Other languages
English (en)
Other versions
DK593886D0 (da
Inventor
Paul Elliot Bender
Don Edgar Griswold
Nabil Hanna
Henry Martin Sarau
Original Assignee
Smithkline Beckman Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beckman Corp filed Critical Smithkline Beckman Corp
Publication of DK593886D0 publication Critical patent/DK593886D0/da
Publication of DK593886A publication Critical patent/DK593886A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/88—Nitrogen atoms, e.g. allantoin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Fodder In General (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK593886A 1985-12-12 1986-12-10 Forbindelser og farmaceutiske praeparater der inhiberer 5-lipoxygenase-vejen DK593886A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US80839585A 1985-12-12 1985-12-12
US06/856,927 US4686231A (en) 1985-12-12 1986-04-28 Inhibition of 5-lipoxygenase products

Publications (2)

Publication Number Publication Date
DK593886D0 DK593886D0 (da) 1986-12-10
DK593886A true DK593886A (da) 1987-06-13

Family

ID=27123119

Family Applications (1)

Application Number Title Priority Date Filing Date
DK593886A DK593886A (da) 1985-12-12 1986-12-10 Forbindelser og farmaceutiske praeparater der inhiberer 5-lipoxygenase-vejen

Country Status (7)

Country Link
US (1) US4686231A (da)
EP (1) EP0236628B1 (da)
AT (1) ATE82968T1 (da)
AU (1) AU586907B2 (da)
DE (1) DE3687224T2 (da)
DK (1) DK593886A (da)
PT (1) PT83902B (da)

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US6677364B2 (en) * 1998-04-20 2004-01-13 G.D. Searle & Co. Substituted sulfonylphenylheterocycles as cyclooxygenase-2 and 5-lipoxygenase inhibitors
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US5929076A (en) * 1997-01-10 1999-07-27 Smithkline Beecham Corporation Cycloalkyl substituted imidazoles
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US6562832B1 (en) 1997-07-02 2003-05-13 Smithkline Beecham Corporation Substituted imidazole compounds
US7301021B2 (en) * 1997-07-02 2007-11-27 Smithkline Beecham Corporation Substituted imidazole compounds
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TW517055B (en) 1997-07-02 2003-01-11 Smithkline Beecham Corp Novel substituted imidazole compounds
EP1041989A4 (en) 1997-10-08 2002-11-20 Smithkline Beecham Corp NEW SUBSTITUTED CYCLOALCENYL COMPOUNDS
JP2001526230A (ja) 1997-12-19 2001-12-18 スミスクライン・ビーチャム・コーポレイション ヘテロアリール置換イミダゾール化合物、その医薬組成物および使用
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US6858617B2 (en) 1998-05-26 2005-02-22 Smithkline Beecham Corporation Substituted imidazole compounds
ATE266399T1 (de) * 1998-08-20 2004-05-15 Smithkline Beecham Corp Neue substituierte triazolverbindungen
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EP1233950B1 (en) 1999-11-23 2005-10-05 Smithkline Beecham Corporation 3,4-DIHYDRO-(1H)QUINAZOLIN-2-ONE COMPOUNDS AS CSBP/P39 kINASE INHIBITORS
US6759410B1 (en) * 1999-11-23 2004-07-06 Smithline Beecham Corporation 3,4-dihydro-(1H)-quinazolin-2-ones and their use as CSBP/p38 kinase inhibitors
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US7235551B2 (en) * 2000-03-02 2007-06-26 Smithkline Beecham Corporation 1,5-disubstituted-3,4-dihydro-1h-pyrimido[4,5-d]pyrimidin-2-one compounds and their use in treating csbp/p38 kinase mediated diseases
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US7329401B2 (en) * 2002-04-15 2008-02-12 The Regents Of The University Of California Cyclooxygenase-2 selective agents useful as imaging probes and related methods
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Also Published As

Publication number Publication date
DK593886D0 (da) 1986-12-10
PT83902A (en) 1987-01-01
PT83902B (en) 1988-10-31
EP0236628A1 (en) 1987-09-16
ATE82968T1 (de) 1992-12-15
DE3687224D1 (de) 1993-01-14
AU6645286A (en) 1987-06-18
AU586907B2 (en) 1989-07-27
US4686231A (en) 1987-08-11
DE3687224T2 (de) 1993-04-08
EP0236628B1 (en) 1992-12-02

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