DK590787A - Cephalosporinsulfonforbindelse, fremgangsmaade og mellemprodukt til fremstilling deraf samt farmaceutisk praeparat indeholdende en saadan forbindelse - Google Patents

Cephalosporinsulfonforbindelse, fremgangsmaade og mellemprodukt til fremstilling deraf samt farmaceutisk praeparat indeholdende en saadan forbindelse

Info

Publication number
DK590787A
DK590787A DK590787A DK590787A DK590787A DK 590787 A DK590787 A DK 590787A DK 590787 A DK590787 A DK 590787A DK 590787 A DK590787 A DK 590787A DK 590787 A DK590787 A DK 590787A
Authority
DK
Denmark
Prior art keywords
sulphones
cephalosporin
intermediates
procedures
preparing
Prior art date
Application number
DK590787A
Other languages
Danish (da)
English (en)
Other versions
DK590787D0 (da
Inventor
James B Doherty
Paul E Finke
Raymond A Firestone
Wiliam K Hagmann
Shrenik K Shah
Kevan R Thompson
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of DK590787D0 publication Critical patent/DK590787D0/da
Publication of DK590787A publication Critical patent/DK590787A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DK590787A 1986-11-12 1987-11-11 Cephalosporinsulfonforbindelse, fremgangsmaade og mellemprodukt til fremstilling deraf samt farmaceutisk praeparat indeholdende en saadan forbindelse DK590787A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US93019386A 1986-11-12 1986-11-12

Publications (2)

Publication Number Publication Date
DK590787D0 DK590787D0 (da) 1987-11-11
DK590787A true DK590787A (da) 1988-05-13

Family

ID=25459038

Family Applications (1)

Application Number Title Priority Date Filing Date
DK590787A DK590787A (da) 1986-11-12 1987-11-11 Cephalosporinsulfonforbindelse, fremgangsmaade og mellemprodukt til fremstilling deraf samt farmaceutisk praeparat indeholdende en saadan forbindelse

Country Status (16)

Country Link
EP (1) EP0267723B1 (fr)
JP (1) JPS63198688A (fr)
KR (1) KR880006249A (fr)
CN (1) CN87107753A (fr)
AT (1) ATE133954T1 (fr)
AU (1) AU611104B2 (fr)
CA (1) CA1339275C (fr)
DE (1) DE3751700D1 (fr)
DK (1) DK590787A (fr)
FI (1) FI874839A (fr)
HU (1) HUT52511A (fr)
IL (1) IL84359A0 (fr)
NO (1) NO874699L (fr)
NZ (1) NZ222399A (fr)
PT (1) PT86074B (fr)
ZA (1) ZA878467B (fr)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8808701D0 (en) * 1988-04-13 1988-05-18 Erba Carlo Spa Beta-lactam derivatives
GB8811388D0 (en) * 1988-05-13 1988-06-15 Erba Carlo Spa 1,1-dioxo-cephem-4-carbothiolic acid derivatives
US4992541A (en) * 1989-08-01 1991-02-12 Merck & Co., Inc. Process for the preparation of 1,1-dioxo-7-substituted cephems
AU661453B2 (en) * 1989-10-06 1995-07-27 Synphar Laboratories, Inc. Novel 2-spirocyclopropyl cephalosporin sulfone derivatives and processes for the preparation thereof
US5264429A (en) * 1989-10-06 1993-11-23 Synphar Laboratories, Inc. 2-spirocyclopropyl cephalosporin sulfone derivatives
US5258377A (en) * 1991-04-08 1993-11-02 Taiho Pharmaceutical Co., Ltd. 2-spirocyclopropyl 4-acylcephems
US5348953A (en) * 1991-06-25 1994-09-20 Merck & Co., Inc. Substituted azetidinones as anti-inflammatory and antidegenerative agents
DE69331089T2 (de) * 1992-02-18 2002-07-18 Otsuka Kagaku K.K., Osaka Beta-Laktam und Cepham Verbindungen und Ihre Herstellung
GB2266526A (en) * 1992-03-17 1993-11-03 Merck & Co Inc Substituted cephalosporin sulfones useful in the treatment of leukemia
GB2266525A (en) * 1992-03-17 1993-11-03 Merck & Co Inc Substituted cephalosporin sulfone compositions useful in the treatment of leukemia
WO1993024493A1 (fr) * 1992-05-27 1993-12-09 Teijin Limited Derive de cephalosporine
CA2147129A1 (fr) * 1992-10-27 1994-05-11 James B. Doherty Nouvelles azetidinones substituees utilisees comme agents anti-inflammatoires et anti-degeneratifs
US5591737A (en) * 1992-12-17 1997-01-07 Merck & Co., Inc. Substituted azetidinones as anti-inflammatory and antidegenerative agents
US5439904A (en) * 1993-12-07 1995-08-08 Synphar Laboratories, Inc. 2-spiro(2'-spirocycloalkyl)cyclopropyl cephalosporin sulfones as antiinflammatory and antigenerative agents
US5747485A (en) * 1995-04-13 1998-05-05 Merck & Co., Inc. Substituted azetidiones as anti-inflammatory and antidegenerative agents
WO1997007805A1 (fr) * 1995-08-31 1997-03-06 Smithkline Beecham Corporation Enzyme de conversion d'interleukines et apoptose
WO1997008174A1 (fr) * 1995-08-31 1997-03-06 Smithkline Beecham Corporation Enzyme de conversion d'interleukine et apoptose
GB9525697D0 (en) * 1995-12-15 1996-02-14 Pharmacia Spa Cephem derivatives
CN106543206B (zh) * 2016-09-22 2018-08-31 济南康和医药科技有限公司 一种头孢类二聚体化合物的制备方法
CN113372368B (zh) * 2020-03-09 2022-04-12 苏州爱科百发生物医药技术有限公司 一种弹性蛋白酶抑制剂前药及其用途

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4623645A (en) * 1983-04-18 1986-11-18 Merck & Co., Inc. Substituted cephalosporin sulfoxides as anti-inflammatory and antidegenerative agents
EP0124081A3 (fr) * 1983-05-02 1986-11-26 Merck & Co. Inc. Céphalosporinesulfones comme agents anti-inflammatoires et anti-dégénératifs, compositions pharmaceutiques les contenant et procédés pour les fabriquer
US4699904A (en) * 1985-07-01 1987-10-13 Merck & Co., Inc. Tetrazolyl derivatives of β-lactams useful as elastase inhibitors

Also Published As

Publication number Publication date
NO874699D0 (no) 1987-11-11
DE3751700D1 (de) 1996-03-21
CA1339275C (fr) 1997-08-12
KR880006249A (ko) 1988-07-22
IL84359A0 (en) 1988-04-29
FI874839A (fi) 1988-05-13
NO874699L (no) 1988-05-13
EP0267723A2 (fr) 1988-05-18
AU611104B2 (en) 1991-06-06
HUT52511A (en) 1990-07-28
NZ222399A (en) 1991-07-26
PT86074A (en) 1987-12-01
ZA878467B (en) 1988-09-28
CN87107753A (zh) 1988-06-29
DK590787D0 (da) 1987-11-11
ATE133954T1 (de) 1996-02-15
EP0267723A3 (en) 1989-12-06
PT86074B (pt) 1990-11-07
EP0267723B1 (fr) 1996-02-07
FI874839A0 (fi) 1987-11-03
AU8062487A (en) 1988-05-19
JPS63198688A (ja) 1988-08-17

Similar Documents

Publication Publication Date Title
DK590787D0 (da) Cephalosporinsulfonforbindelse, fremgangsmaade og mellemprodukt til fremstilling deraf samt farmaceutisk praeparat indeholdende en saadan forbindelse
DK159386D0 (da) Substitueret azetidinon og farmaceutisk praeparat indeholdende en saadan forbindelse
FI906438A (fi) Menetelmä uusien, terapeuttisesti käyttökelpoisten A-nor-steroidi-3-karboksyylihappojohdannaisten valmistamiseksi
KR870700620A (ko) 신규 약리학적 화합물
IT8547924A0 (it) Medicamenti per uso topico, ottenuti tramite l'impiego dell'acido ialuronico
FI854227A0 (fi) Menetelmä analgeettisena aineena käyttökelpoisten polypeptidien valmistamiseksi
FI931855A0 (fi) Farmaceutisk sammansaettning som innehaoller kinolin- och kinazolinderivat samt nya foereningar daerfoer
FI871087A (fi) Menetelmä terapeuttisesti aktiivisten 1,2,3,4-tetrahydro-3-karbamoyyli-2-tiokso/okso-5-pyrimidiinikarboksyylihappojohdannaisten valmistamiseksi
DK240889A (da) S-enantiomere glutaramidderivater og deres anvendelse som laegemidler samt farmaceutiske praeparater indeholdende disse forbindelser
ES556351A0 (es) Un procedimiento para preparar derivados de pirrolidona
FI864970A (fi) Nya kristallina salter av aryloxi-propanolaminer, foerfarande foer deras framstaellning och deras anvaendning.
FI863471A (fi) Menetelmä terapeuttisesti käyttökelpoisten 3-desmetyylimevalonihappojohdannaisten valmistamiseksi
FI890678A (fi) Analogiamenetelmä terapeuttisesti käyttökelpoisten 1,3-dioksaanialkeenihappojohdannaisten valmistamiseksi
NO303829B1 (no) Nye benzylalkoholderivater, mellomprodukter, farmas°ytiske preparater inneholdende de nye forbindelsene samt deres anvendelse
NO164243C (no) Analogifremgangsmaate for fremstilling av nye terapeutisk aktive 16,17-acetalsubstituerte pregnan-21-oinsyrederivater
NO864525D0 (no) Fremgangsmaate ved fremstilling av aryleddiksyrederivater.
IT1226897B (it) Derivato di taurina, sua preparazione e composizioni farmaceutiche relative
DK204891D0 (da) Hidtil ukendte cyanoalkylbenzamidderivater, fremgangsmaade til fremstilling deraf, samt anvendelse af saadanne cyanoalkylbenzamidderivater som mellemprodukt ved fremstilling af substituerede n-(imidazolinyl-methyl)-benzamider
FI103789B (fi) Välituotteita farmaseuttisesti käyttökelpoisten kinoliini-3-karboksyylihappojohdannaisten valmistamiseksi
DE3685712D1 (de) Dermatica.
IT1173763B (it) Derivati dell'acido 3-mercapto-2-oxo-1-pirrolidinacetico,procedimento di preparazione e composizioni farmaceutiche che li contengono
FI921238A0 (fi) Välituotteina käytettävät N'-alkoksi- tai N'-aralkyylioksi-N6-syano-griseoliinihapon johdannaiset

Legal Events

Date Code Title Description
AHB Application shelved due to non-payment