DK584488A - Isoquinolinderivater - Google Patents

Isoquinolinderivater

Info

Publication number
DK584488A
DK584488A DK584488A DK584488A DK584488A DK 584488 A DK584488 A DK 584488A DK 584488 A DK584488 A DK 584488A DK 584488 A DK584488 A DK 584488A DK 584488 A DK584488 A DK 584488A
Authority
DK
Denmark
Prior art keywords
aryl
derivatives
lower alkyl
lower alkoxy
isoquinoline
Prior art date
Application number
DK584488A
Other languages
English (en)
Other versions
DK168069B1 (da
DK584488D0 (da
Inventor
Emil Albin Broger
Yvo Crameri
Bernd Heiser
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of DK584488D0 publication Critical patent/DK584488D0/da
Publication of DK584488A publication Critical patent/DK584488A/da
Application granted granted Critical
Publication of DK168069B1 publication Critical patent/DK168069B1/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0046—Ruthenium compounds
    • C07F15/0053—Ruthenium compounds without a metal-carbon linkage
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/18—Aralkyl radicals
    • C07D217/20—Aralkyl radicals with oxygen atoms directly attached to the aromatic ring of said aralkyl radical, e.g. papaverine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Catalysts (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK584488A 1987-11-11 1988-10-20 Isoquinolinderivater og en fremgangsmaade til fremstilling af octahydroisoquinoliner ud fra derivaterne DK168069B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP87810651 1987-11-11
EP87810651 1987-11-11

Publications (3)

Publication Number Publication Date
DK584488D0 DK584488D0 (da) 1988-10-20
DK584488A true DK584488A (da) 1989-05-12
DK168069B1 DK168069B1 (da) 1994-01-31

Family

ID=8198427

Family Applications (1)

Application Number Title Priority Date Filing Date
DK584488A DK168069B1 (da) 1987-11-11 1988-10-20 Isoquinolinderivater og en fremgangsmaade til fremstilling af octahydroisoquinoliner ud fra derivaterne

Country Status (6)

Country Link
US (1) US4857648A (da)
EP (1) EP0315886B1 (da)
JP (1) JP2579677B2 (da)
AT (1) ATE118482T1 (da)
DE (1) DE3853043T2 (da)
DK (1) DK168069B1 (da)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4791107A (en) * 1986-07-16 1988-12-13 Hoechst-Roussel Pharmaceuticals, Inc. Memory enhancing and analgesic 1,2,3,3A,8,8A-hexahydro-3A,8 (and) 1,3A,8)-di(and tri)methylpyrrolo(2,3-B)indoles, compositions and use
DE59009525D1 (de) * 1989-05-10 1995-09-21 Hoffmann La Roche Herstellung von Isochinolinderivaten.
JPH0692427B2 (ja) * 1989-07-11 1994-11-16 高砂香料工業株式会社 ２，２’―ビス（ジシクロヘキシルホスフィノ）―６，６’―ジメチル―１，１’―ビフェニルを配位子とする錯体，およびその錯体を用いた有機カルボン酸とそのエステルの製造方法
AU685820B2 (en) * 1990-06-27 1998-01-29 Hoechst-Roussel Pharmaceuticals Incorporated Tetrahydroisoquinolinylcarbamates of 1,2,3,3A,8,8A-hexahydro-1,3A,8-trimethylpyrrolo(2,3-B)indole
ATE163183T1 (de) * 1990-06-27 1998-02-15 Hoechst Marion Roussel Inc Tetrahydroisochinolinylcarbamate von 1,2,3,3a,8,8a-hexahydro-1,3a,8-trimethylpyrrolo (2,3-b> indol
US5084461A (en) * 1991-03-27 1992-01-28 Merrell Dow Pharmaceuticals Inc. Azadecalin amides and thioamides as inhibitors of cholesterol biosynthesis
US5350758A (en) * 1992-07-08 1994-09-27 Merrell Dow Pharmaceuticals Inc. Piperidyl sulfonamides and sulfoxamides as inhibitors of cholesterol biosynthesis
EP0834506B1 (de) * 1996-10-02 2004-01-14 F. Hoffmann-La Roche Ag Verfahren zur Herstellung von (9alpha, 13alpha, 14alpha)-1-(3-Methoxymorphinan-17-yl)alkanonen
EP0834505B1 (de) * 1996-10-02 2004-01-07 F. Hoffmann-La Roche Ag Verfahren zur Herstellung von (Z)-1-[1-(4-Methoxybenzyliden)-1,2,3,4,5,6,7,8-octahydro-isochinolin-2-yl]alkanonen
US5905153A (en) * 1996-10-02 1999-05-18 Roche Vitamins Inc. Process for preparing (9α,13α,14α)-1-(3-methoxy-morphinan-17-yl)alkanones
US5849917A (en) * 1996-10-02 1998-12-15 Roche Vitamins Inc. Process for the preparation of isoquinoline compounds
DE19706396A1 (de) * 1996-12-09 1998-06-10 Bayer Ag Verfahren zur Herstellung von 3-(l-Hydroxiphenyl-l-alkoximinomethyl)dioxazinen
US5880285A (en) * 1996-12-23 1999-03-09 Roche Vitamins Inc. Process for manufacture of optically active isochinole compounds
CN103265489B (zh) * 2013-06-17 2015-03-25 苏州立新制药有限公司 ent-(14S)-3-甲氧基-17-甲基吗喃的制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB685750A (en) * 1949-10-14 1953-01-07 Hoffmann La Roche Improvements in or relating to isoquinoline derivatives
US3634429A (en) * 1969-09-30 1972-01-11 Hoffmann La Roche Morphinan derivatives and preparation thereof
US4247697A (en) * 1979-09-10 1981-01-27 Hoffmann-La Roche Inc. 3-Phenoxy morphinans and their derivatives
US4514569A (en) * 1982-01-28 1985-04-30 Hendrickson James B Synthesis of 1-substituted isoquinolines
DE3436179A1 (de) * 1984-10-03 1986-04-10 Merck Patent Gmbh, 6100 Darmstadt Verfahren zur herstellung optisch aktiver amine
JPS62265266A (ja) * 1986-05-13 1987-11-18 Takasago Corp Ｎ−アシル−テトラヒドロイソキノリン類の製造法

Also Published As

Publication number Publication date
DE3853043T2 (de) 1995-06-08
JPH01160965A (ja) 1989-06-23
EP0315886A2 (en) 1989-05-17
DE3853043D1 (de) 1995-03-23
EP0315886A3 (en) 1990-04-25
JP2579677B2 (ja) 1997-02-05
ATE118482T1 (de) 1995-03-15
US4857648A (en) 1989-08-15
DK168069B1 (da) 1994-01-31
EP0315886B1 (en) 1995-02-15
DK584488D0 (da) 1988-10-20

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Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PBP Patent lapsed