DK579374A - - Google Patents

Info

Publication number
DK579374A
DK579374A DK579374A DK579374A DK579374A DK 579374 A DK579374 A DK 579374A DK 579374 A DK579374 A DK 579374A DK 579374 A DK579374 A DK 579374A DK 579374 A DK579374 A DK 579374A
Authority
DK
Denmark
Application number
DK579374A
Other languages
Danish (da)
Other versions
DK136470C (ja
DK136470B (da
Inventor
M Hoffer
I Kompis
Original Assignee
Hoffmann-La F Roche & Co Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH1568073A external-priority patent/CH591457A5/de
Priority claimed from CH1424374A external-priority patent/CH605827A5/de
Application filed by Hoffmann-La F Roche & Co Ag filed Critical Hoffmann-La F Roche & Co Ag
Publication of DK579374A publication Critical patent/DK579374A/da
Publication of DK136470B publication Critical patent/DK136470B/da
Application granted granted Critical
Publication of DK136470C publication Critical patent/DK136470C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48Two nitrogen atoms
    • C07D239/49Two nitrogen atoms with an aralkyl radical, or substituted aralkyl radical, attached in position 5, e.g. trimethoprim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C245/00Compounds containing chains of at least two nitrogen atoms with at least one nitrogen-to-nitrogen multiple bond
    • C07C245/02Azo compounds, i.e. compounds having the free valencies of —N=N— groups attached to different atoms, e.g. diazohydroxides
    • C07C245/06Azo compounds, i.e. compounds having the free valencies of —N=N— groups attached to different atoms, e.g. diazohydroxides with nitrogen atoms of azo groups bound to carbon atoms of six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C245/00Compounds containing chains of at least two nitrogen atoms with at least one nitrogen-to-nitrogen multiple bond
    • C07C245/02Azo compounds, i.e. compounds having the free valencies of —N=N— groups attached to different atoms, e.g. diazohydroxides
    • C07C245/06Azo compounds, i.e. compounds having the free valencies of —N=N— groups attached to different atoms, e.g. diazohydroxides with nitrogen atoms of azo groups bound to carbon atoms of six-membered aromatic rings
    • C07C245/08Azo compounds, i.e. compounds having the free valencies of —N=N— groups attached to different atoms, e.g. diazohydroxides with nitrogen atoms of azo groups bound to carbon atoms of six-membered aromatic rings with the two nitrogen atoms of azo groups bound to carbon atoms of six-membered aromatic rings, e.g. azobenzene
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C37/00Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring
    • C07C37/50Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by reactions decreasing the number of carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/41Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by hydrogenolysis or reduction of carboxylic groups or functional derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/63Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00Compounds having —CHO groups
    • C07C47/52Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
    • C07C47/575Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing ether groups, groups, groups, or groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/145Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK579374AA 1973-11-08 1974-11-06 Analogifremgangsmåde til fremstilling af 2,4-diamino-5-benzylpyrimidinderivater eller salte deraf. DK136470B (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US41403073A 1973-11-08 1973-11-08
CH1568073A CH591457A5 (ja) 1973-11-08 1973-11-08
CH1424374A CH605827A5 (en) 1973-11-08 1974-10-24 2,4-diamino-5-(3,5-dialkoxy-4-halo-benzyl)-pyrimidines

Publications (3)

Publication Number Publication Date
DK579374A true DK579374A (ja) 1975-07-07
DK136470B DK136470B (da) 1977-10-17
DK136470C DK136470C (ja) 1978-03-20

Family

ID=27177143

Family Applications (1)

Application Number Title Priority Date Filing Date
DK579374AA DK136470B (da) 1973-11-08 1974-11-06 Analogifremgangsmåde til fremstilling af 2,4-diamino-5-benzylpyrimidinderivater eller salte deraf.

Country Status (9)

Country Link
JP (1) JPS6119628B2 (ja)
AT (1) AT342597B (ja)
CA (1) CA1017743A (ja)
DE (1) DE2452889C2 (ja)
DK (1) DK136470B (ja)
FR (1) FR2250533B1 (ja)
GB (2) GB1449387A (ja)
NL (1) NL184619C (ja)
SE (1) SE419444B (ja)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR71725B (ja) * 1977-11-10 1983-06-22 Hoffmann La Roche
DE2910510A1 (de) * 1979-03-16 1980-09-25 Heumann Ludwig & Co Gmbh 2,4-diamino-5-benzylpyrimidine, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
ZW10681A1 (en) * 1980-06-26 1982-02-24 Hoffmann La Roche Antibacterial agents
CH651473A5 (de) * 1982-07-29 1985-09-30 Joachim Karl Prof Dr Seydel Pharmazeutisches praeparat.
HU188588B (en) * 1982-08-13 1986-04-28 Egyt Gyogyszervegyeszeti Gyar Process for the production of 2,4-diamino-5-benzyl-pyrimidine-derivatives
IT1212907B (it) * 1983-12-21 1989-11-30 Romeo Aurelio Preparazione di fenoli alogenati
GB2360299B (en) * 2000-03-01 2004-09-29 Portakabin Ltd Prefabricated building unit with fascia system

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1103931B (de) * 1957-02-21 1961-04-06 Wellcome Found Verfahren zur Herstellung von 2, 4-Diamino-5-benzylpyrimidinderivaten
US3485840A (en) * 1964-11-12 1969-12-23 Hoffmann La Roche 2,4-diamino - 5 - (2',4',5'-substituted benzyl) pyrimidines,intermediates and processes

Also Published As

Publication number Publication date
JPS6119628B2 (ja) 1986-05-17
AU7510574A (en) 1976-05-13
DK136470C (ja) 1978-03-20
NL184619C (nl) 1989-09-18
SE419444B (sv) 1981-08-03
FR2250533B1 (ja) 1978-07-21
GB1449388A (en) 1976-09-15
DE2452889A1 (de) 1975-05-15
NL184619B (nl) 1989-04-17
SE7413958L (ja) 1975-05-09
JPS5077378A (ja) 1975-06-24
GB1449387A (en) 1976-09-15
AT342597B (de) 1978-04-10
CA1017743A (en) 1977-09-20
DK136470B (da) 1977-10-17
FR2250533A1 (ja) 1975-06-06
NL7414528A (nl) 1975-05-12
DE2452889C2 (de) 1985-09-19
ATA892374A (de) 1977-08-15

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Legal Events

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PUP Patent expired