DK55086A - Fremgangsmaade til udtrykkelse af human protein c-aktivitet og vektorertil brug ved fremgangsmaaden - Google Patents

Fremgangsmaade til udtrykkelse af human protein c-aktivitet og vektorertil brug ved fremgangsmaaden Download PDF

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Publication number
DK55086A
DK55086A DK55086A DK55086A DK55086A DK 55086 A DK55086 A DK 55086A DK 55086 A DK55086 A DK 55086A DK 55086 A DK55086 A DK 55086A DK 55086 A DK55086 A DK 55086A
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Denmark
Prior art keywords
protein
activity
procedure
produce
human protein
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DK55086A
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Danish (da)
English (en)
Other versions
DK55086D0 (da
Inventor
Nils Ulrik Bang
Robert John Beckmann
Jr Stanley Richard Jaskunas
Mei-Huei Tsai Lai
Sheila Parks Little
George Louis Long
Robert Frank Santerre
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Lilly Co Eli
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24811674&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK55086(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of DK55086D0 publication Critical patent/DK55086D0/da
Publication of DK55086A publication Critical patent/DK55086A/da

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6464—Protein C (3.4.21.69)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21069—Protein C activated (3.4.21.69)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/832—Bacillus
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/848—Escherichia
    • Y10S435/849—Escherichia coli
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/886—Streptomyces

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DK55086A 1985-02-08 1986-02-05 Fremgangsmaade til udtrykkelse af human protein c-aktivitet og vektorertil brug ved fremgangsmaaden DK55086A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/699,967 US4775624A (en) 1985-02-08 1985-02-08 Vectors and compounds for expression of human protein C

Publications (2)

Publication Number Publication Date
DK55086D0 DK55086D0 (da) 1986-02-05
DK55086A true DK55086A (da) 1986-08-09

Family

ID=24811674

Family Applications (2)

Application Number Title Priority Date Filing Date
DK55086A DK55086A (da) 1985-02-08 1986-02-05 Fremgangsmaade til udtrykkelse af human protein c-aktivitet og vektorertil brug ved fremgangsmaaden
DK55486A DK55486D0 (da) 1985-02-08 1986-02-05 Fremgangsmaade til udtrykkelse af human protein c-aktivitet og vektor til brug ved fremgangsmaaden

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK55486A DK55486D0 (da) 1985-02-08 1986-02-05 Fremgangsmaade til udtrykkelse af human protein c-aktivitet og vektor til brug ved fremgangsmaaden

Country Status (21)

Country Link
US (2) US4775624A (de)
EP (1) EP0191606B2 (de)
JP (6) JPH0698002B2 (de)
KR (1) KR860006546A (de)
CN (1) CN86100868A (de)
AT (1) ATE85079T1 (de)
AU (1) AU593538B2 (de)
CA (1) CA1341073C (de)
DE (2) DE3687584D1 (de)
DK (2) DK55086A (de)
ES (2) ES8704206A1 (de)
GR (1) GR860334B (de)
HU (1) HU211032B (de)
IE (1) IE59423B1 (de)
IL (1) IL77781A (de)
MY (1) MY103018A (de)
NZ (1) NZ215031A (de)
PH (1) PH25396A (de)
PT (1) PT81959B (de)
SG (1) SG50631A1 (de)
ZA (1) ZA86780B (de)

Families Citing this family (103)

* Cited by examiner, † Cited by third party
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US5981216A (en) * 1985-04-01 1999-11-09 Alusuisse Holdings A.G. Transformed myeloma cell-line and a process for the expression of a gene coding for a eukaryotic polypeptide employing same
ATE74164T1 (de) * 1985-04-22 1992-04-15 Genetics Inst Herstellung mit hoher leistung des aktivfaktors ix.
US4968626A (en) * 1985-08-15 1990-11-06 Board Of Reagents Of The University Of Washington DNA sequence coding for protein C
US5516650A (en) * 1985-06-27 1996-05-14 Zymogenetics, Inc. Production of activated protein C
EP0215548B2 (de) * 1985-06-27 1998-01-07 Zymogenetics, Inc. Expression von Protein C
US4959318A (en) * 1985-06-27 1990-09-25 Zymogenetics, Inc. Expression of protein C
USRE38981E1 (en) * 1985-08-15 2006-02-14 Board Of Regents Of The University Of Washington DNA sequence coding for protein C
US5618715A (en) * 1985-12-20 1997-04-08 Oncogen Limited Partnership Oncostatin M and novel compositions having anti-neoplastic activity
GB8607502D0 (en) * 1986-03-26 1986-04-30 Antibioticos Sa Penicillium chrysogenum
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US5550036A (en) * 1986-04-09 1996-08-27 Eli Lilly And Company Method for co-amplification of human protein C genes in human cells
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CA2612859A1 (en) * 2005-06-23 2006-12-28 The University Of British Columbia Coagulation factor iii polymorphisms associated with prediction of subject outcome and response to therapy
EP1898945B1 (de) * 2005-06-24 2012-12-19 Drugrecure ApS Atemwegs-administration eines standort-deaktivierten fviia bei entzündungskrankheiten, die den atemtrakt betreffen
CA2654761A1 (en) * 2006-06-09 2007-12-13 The University Of British Columbia Interferon gamma polymorphisms as indicators of subject outcome in critically ill subjects
WO2008048646A1 (en) * 2006-10-18 2008-04-24 Socratech L.L.C. Use of human protein c with altered glycosylation and sialic acid content as a medicament
EP2078074A4 (de) * 2006-10-31 2011-09-28 Scripps Research Inst Dosierplan für aktiviertes protein-c und varianten mit verminderter gerinnungshemmender wirkung
CA2712057A1 (en) * 2008-01-15 2009-07-23 The University Of British Columbia Protein c rs2069915 as a response predictor to survival and administration of activated protein c or protein c-like compound
RU2469093C2 (ru) * 2008-12-19 2012-12-10 Общество с ограниченной ответственностью "Лаборатория медицинской биотехнологии" (ООО "ЛМБТ") ЭКСПРЕССИОННАЯ ПЛАЗМИДНАЯ ДНК pCID-PROC, КОДИРУЮЩАЯ ПРОТЕИН С ЧЕЛОВЕКА, И КЛЕТОЧНАЯ ЛИНИЯ DG-CID-PROC-1, ПРОДУЦИРУЮЩАЯ РЕКОМБИНАНТНЫЙ ПРОТЕИН С ЧЕЛОВЕКА
WO2012068519A2 (en) 2010-11-19 2012-05-24 Sirius Genomics Inc. Markers associated with response to activated protein c administration, and uses thereof
US20150150954A1 (en) 2012-07-04 2015-06-04 The University Of Sydney Treatment of inflammatory skin disorders
CA2946032C (en) 2014-04-16 2022-06-14 Zz Biotech Llc Use of apc analogue for wound healing
CA2946028C (en) 2014-04-16 2022-10-11 Zz Biotech Llc Treatment of abnormal cutaneous scarring
KR102307278B1 (ko) 2014-04-29 2021-09-30 노파르티스 아게 신규 척추동물 세포 및 관심 폴리펩티드의 재조합적 발현 방법
WO2023119230A1 (en) 2021-12-22 2023-06-29 L'oreal Coagulation pathway and nicotinamide-adenine dinucleotide pathway modulating compositions and methods of their use

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Also Published As

Publication number Publication date
JPH06220092A (ja) 1994-08-09
PH25396A (en) 1991-06-03
IE860328L (en) 1986-08-08
AU593538B2 (en) 1990-02-15
US5151268A (en) 1992-09-29
JPH09273A (ja) 1997-01-07
JP2992002B2 (ja) 1999-12-20
DK55486D0 (da) 1986-02-05
US4775624A (en) 1988-10-04
GR860334B (en) 1986-06-05
DE3687584T4 (de) 2001-07-26
ES8707764A1 (es) 1987-08-16
CA1341073C (en) 2000-08-08
DE3687584T3 (de) 2001-05-03
HUT40168A (en) 1986-11-28
EP0191606B2 (de) 2001-01-24
KR860006546A (ko) 1986-09-13
JPH0759190B2 (ja) 1995-06-28
JP2854283B2 (ja) 1999-02-03
DE3687584T2 (de) 1993-05-27
PT81959B (pt) 1988-07-01
PT81959A (en) 1986-03-01
IL77781A (en) 1991-08-16
JP2873153B2 (ja) 1999-03-24
ATE85079T1 (de) 1993-02-15
ES8704206A1 (es) 1987-03-16
JPH08317794A (ja) 1996-12-03
JPH0698002B2 (ja) 1994-12-07
MY103018A (en) 1993-04-30
ES557100A0 (es) 1987-08-16
EP0191606B1 (de) 1993-01-27
JPH10327876A (ja) 1998-12-15
ZA86780B (en) 1987-09-30
EP0191606A2 (de) 1986-08-20
HU211032B (en) 1995-09-28
JPS61205487A (ja) 1986-09-11
ES551761A0 (es) 1987-03-16
SG50631A1 (en) 1998-07-20
AU5325686A (en) 1986-08-14
NZ215031A (en) 1988-02-29
IE59423B1 (en) 1994-02-23
EP0191606A3 (en) 1987-01-21
JPH06189782A (ja) 1994-07-12
CN86100868A (zh) 1986-09-24
JP2854282B2 (ja) 1999-02-03
DE3687584D1 (de) 1993-03-11
DK55086D0 (da) 1986-02-05

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