DK539980A - Fremgangsmaade til fremstilling af 2-metyl-6-substituerede-4-i (2,3-diklorfenyl-1,4-dihydropyridin)-3,5-dikarboxylsyre-3,5-destere - Google Patents

Fremgangsmaade til fremstilling af 2-metyl-6-substituerede-4-i (2,3-diklorfenyl-1,4-dihydropyridin)-3,5-dikarboxylsyre-3,5-destere

Info

Publication number
DK539980A
DK539980A DK539980A DK539980A DK539980A DK 539980 A DK539980 A DK 539980A DK 539980 A DK539980 A DK 539980A DK 539980 A DK539980 A DK 539980A DK 539980 A DK539980 A DK 539980A
Authority
DK
Denmark
Prior art keywords
desters
dichlorphenyl
dihydropyridine
substituted
methyl
Prior art date
Application number
DK539980A
Other languages
English (en)
Inventor
P B Berntsson
S Aa I Carlsson
J O Gaarder
B R Ljung
Original Assignee
Haessle Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Haessle Ab filed Critical Haessle Ab
Publication of DK539980A publication Critical patent/DK539980A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
DK539980A 1979-12-20 1980-12-18 Fremgangsmaade til fremstilling af 2-metyl-6-substituerede-4-i (2,3-diklorfenyl-1,4-dihydropyridin)-3,5-dikarboxylsyre-3,5-destere DK539980A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE7910521A SE7910521L (sv) 1979-12-20 1979-12-20 Nya 2-metyl-6-substituerade-4-(2,3-disubstituerad fenyl)-1,4-dihydropyridin-3,5-diestrar med hypotesiva egenskaper, samt forfarande for deras framstellning, och farmaceutiska beredningar innehallande desamma

Publications (1)

Publication Number Publication Date
DK539980A true DK539980A (da) 1981-06-21

Family

ID=20339605

Family Applications (1)

Application Number Title Priority Date Filing Date
DK539980A DK539980A (da) 1979-12-20 1980-12-18 Fremgangsmaade til fremstilling af 2-metyl-6-substituerede-4-i (2,3-diklorfenyl-1,4-dihydropyridin)-3,5-dikarboxylsyre-3,5-destere

Country Status (11)

Country Link
EP (1) EP0031801A3 (da)
JP (1) JPS56127356A (da)
AU (1) AU6542380A (da)
DD (1) DD155519A5 (da)
DK (1) DK539980A (da)
ES (4) ES497927A0 (da)
FI (1) FI803984L (da)
MY (1) MY8500404A (da)
NO (1) NO803856L (da)
SE (1) SE7910521L (da)
ZA (1) ZA807634B (da)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3018259A1 (de) * 1980-05-13 1981-11-19 Bayer Ag, 5090 Leverkusen 1,4-dihydropyridine mit unterschiedlichen substituenten in 2- und 6-position, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln
DK161312C (da) * 1982-03-11 1991-12-09 Pfizer Analogifremgangsmaade til fremstilling af 2-aminoalkoxymethyl-4-phenyl-6-methyl-1,4-dihydropyridin-3,5-dicarboxylsyreestere eller syreadditionssalte deraf samt phthalimidoderivater til anvendelse som udgangsmateriale ved fremgangsmaaden
IL68604A0 (en) * 1982-05-21 1983-09-30 Haessle Ab Processes for preparing therapeutically active dihydropyridines and intermediates for the processes
ATE20064T1 (de) * 1982-07-22 1986-06-15 Pfizer Anti-ischaemische und antihypertensive dihydropyridin-derivate.
HU197881B (en) * 1982-08-06 1989-06-28 Banyu Pharma Co Ltd Process for producing new carbamoyl-oxy-alkyl-carboxy-lic acid derivatives
EP0107293A3 (en) * 1982-09-04 1984-06-06 Pfizer Limited Dihydropyridines
PH19166A (en) * 1982-09-04 1986-01-16 Pfizer Dihydropyridined,pharmaceutical compositions and method of use
US4572908A (en) * 1982-12-21 1986-02-25 Pfizer Inc. Dihydropyridines
US4515799A (en) * 1983-02-02 1985-05-07 Pfizer Inc. Dihydropyridine anti-ischaemic and antihypertensive agents
GB8306666D0 (en) * 1983-03-10 1983-04-13 Pfizer Ltd Therapeutic agents
GB8412208D0 (en) * 1984-05-12 1984-06-20 Pfizer Ltd Quinolone inotropic agents
GB8415386D0 (en) * 1984-06-15 1984-07-18 Pfizer Ltd Therapeutic agents
GB8526411D0 (en) * 1985-10-25 1985-11-27 Pfizer Ltd Dihydropyridines
GB8527698D0 (en) * 1985-11-09 1985-12-11 Pfizer Ltd Dihydropyridine antiischaemic & antihypertensive agents

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2117572C3 (de) * 1971-04-10 1980-03-20 Bayer Ag, 5090 Leverkusen Unsymmetrische 1,4-Dihydropyridin ^-dicarbonsäureester, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel
SE429652B (sv) * 1978-06-30 1983-09-19 Haessle Ab 2.6-dimetyl-4-(2.3-diklorfenyl)-1.4-dihydropyridin-3.5-dikarboxylsyra-3-metylester-5-etylester
CA1117117A (en) * 1978-10-10 1982-01-26 Fujisawa Pharmaceutical Co., Ltd. 2-methyl-dihydropyridine compound, processes for preparation thereof and pharmaceutical composition comprising the same

Also Published As

Publication number Publication date
EP0031801A2 (en) 1981-07-08
ES8306109A1 (es) 1982-10-01
ES8204720A1 (es) 1982-05-01
ES497927A0 (es) 1982-05-01
SE7910521L (sv) 1981-06-21
ES508024A0 (es) 1982-11-16
AU6542380A (en) 1981-06-25
FI803984L (fi) 1981-06-21
ES8307221A1 (es) 1982-11-01
ES508025A0 (es) 1982-11-01
EP0031801A3 (en) 1981-09-16
ES508031A0 (es) 1982-10-01
DD155519A5 (de) 1982-06-16
NO803856L (no) 1981-06-22
JPS56127356A (en) 1981-10-06
MY8500404A (en) 1985-12-31
ZA807634B (en) 1981-11-25
ES8307220A1 (es) 1982-11-16

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