SE7910521L - Nya 2-metyl-6-substituerade-4-(2,3-disubstituerad fenyl)-1,4-dihydropyridin-3,5-diestrar med hypotesiva egenskaper, samt forfarande for deras framstellning, och farmaceutiska beredningar innehallande desamma - Google Patents

Nya 2-metyl-6-substituerade-4-(2,3-disubstituerad fenyl)-1,4-dihydropyridin-3,5-diestrar med hypotesiva egenskaper, samt forfarande for deras framstellning, och farmaceutiska beredningar innehallande desamma

Info

Publication number
SE7910521L
SE7910521L SE7910521A SE7910521A SE7910521L SE 7910521 L SE7910521 L SE 7910521L SE 7910521 A SE7910521 A SE 7910521A SE 7910521 A SE7910521 A SE 7910521A SE 7910521 L SE7910521 L SE 7910521L
Authority
SE
Sweden
Prior art keywords
preparation
new
hypothesive
dihydropyridine
diesters
Prior art date
Application number
SE7910521A
Other languages
English (en)
Swedish (sv)
Inventor
P B Berntsson
S A I Carlsson
J O Gaarder
B R Ljung
Original Assignee
Haessle Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Haessle Ab filed Critical Haessle Ab
Priority to SE7910521A priority Critical patent/SE7910521L/xx
Priority to ZA00807634A priority patent/ZA807634B/xx
Priority to AU65423/80A priority patent/AU6542380A/en
Priority to EP80850190A priority patent/EP0031801A3/en
Priority to NO803856A priority patent/NO803856L/no
Priority to DK539980A priority patent/DK539980A/da
Priority to ES497927A priority patent/ES8204720A1/es
Priority to DD80226363A priority patent/DD155519A5/de
Priority to FI803984A priority patent/FI803984L/fi
Priority to JP18180980A priority patent/JPS56127356A/ja
Publication of SE7910521L publication Critical patent/SE7910521L/xx
Priority to ES508031A priority patent/ES508031A0/es
Priority to ES508025A priority patent/ES8307221A1/es
Priority to ES508024A priority patent/ES8307220A1/es
Priority to MY404/85A priority patent/MY8500404A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
SE7910521A 1979-12-20 1979-12-20 Nya 2-metyl-6-substituerade-4-(2,3-disubstituerad fenyl)-1,4-dihydropyridin-3,5-diestrar med hypotesiva egenskaper, samt forfarande for deras framstellning, och farmaceutiska beredningar innehallande desamma SE7910521L (sv)

Priority Applications (14)

Application Number Priority Date Filing Date Title
SE7910521A SE7910521L (sv) 1979-12-20 1979-12-20 Nya 2-metyl-6-substituerade-4-(2,3-disubstituerad fenyl)-1,4-dihydropyridin-3,5-diestrar med hypotesiva egenskaper, samt forfarande for deras framstellning, och farmaceutiska beredningar innehallande desamma
ZA00807634A ZA807634B (en) 1979-12-20 1980-12-05 New 2-methyl-6-substituted-4-(2,3-dichlorophenyl-1,4-dihydropyridine)-3,5-dicarboxylic acid-3,5-diesters having hypotensive properties,as well as process for their preparation and pharmaceutical preparations containing same
AU65423/80A AU6542380A (en) 1979-12-20 1980-12-16 2-methyl-6-substituted-4-(2,3-dichlorophenyl-1,4-dihydro pyridine)-3,5-dicarboxylic acid-3,5-diester compounds
EP80850190A EP0031801A3 (en) 1979-12-20 1980-12-16 6-substituted 4-(2',3'-dichlorophenyl)-2-methyl-1,4-dihydropyridine-3,5-dicarboxylic acid diesters having hypotensive properties as well as process for their preparation and pharmaceutical preparations containing same
NO803856A NO803856L (no) 1979-12-20 1980-12-18 2-metyl-6-substituerte 4-(2,3-diklorfenyl-1,4-dihydropyridin)-3,5-dikarboksylsyre-3,5-diestere med hypotensive egenskaper, fremgangsmaate for deres fremstilling av farmasoeytiske preparater inneholdende disse
DK539980A DK539980A (da) 1979-12-20 1980-12-18 Fremgangsmaade til fremstilling af 2-metyl-6-substituerede-4-i (2,3-diklorfenyl-1,4-dihydropyridin)-3,5-dikarboxylsyre-3,5-destere
DD80226363A DD155519A5 (de) 1979-12-20 1980-12-19 Verfahren zur herstellung von 2-methyl-4-(2,3-dichlorphenyl)-1,4-dihydropyridin-3,5-dicarbonsaeure-3,5-diestern
ES497927A ES8204720A1 (es) 1979-12-20 1980-12-19 Procedimiento para preparar derivados de dihidropiridina
FI803984A FI803984L (fi) 1979-12-20 1980-12-19 Nya 2-metyl-6-substituerade 4-/2,3-diklorfenyl-1,4-dihydropyridin/-3,5-dikarboxylsyra-3,5-diestrar med hypotensiva egenskaper samt foerfarande foer framstaellning daerav och farmaceutiska preparat innehaollande desamma
JP18180980A JPS56127356A (en) 1979-12-20 1980-12-20 Novel 2-methyl-substituted-4-(2,3-dichlorophenyl- 1,4-dihydropyridine)-3,5-dicarboxylic acid-3,5-diester
ES508031A ES508031A0 (es) 1979-12-20 1981-12-16 Procedimiento para preparar derivados de dihidropiridina.
ES508025A ES8307221A1 (es) 1979-12-20 1981-12-16 "procedimiento para preparar derivados de dihidropiridina".
ES508024A ES8307220A1 (es) 1979-12-20 1981-12-16 "procedimiento para preparar derivados de dihidropiridina".
MY404/85A MY8500404A (en) 1979-12-20 1985-12-30 Dimethyls 4(2,3-dichlorophenyl)1-4 dihydropyriding 3,5-dicarboxylic acid 3-methyl ester 5-ethyl ester having hypotensive propertives, process for its preparation and pharmaceutical preparations containing it

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE7910521A SE7910521L (sv) 1979-12-20 1979-12-20 Nya 2-metyl-6-substituerade-4-(2,3-disubstituerad fenyl)-1,4-dihydropyridin-3,5-diestrar med hypotesiva egenskaper, samt forfarande for deras framstellning, och farmaceutiska beredningar innehallande desamma

Publications (1)

Publication Number Publication Date
SE7910521L true SE7910521L (sv) 1981-06-21

Family

ID=20339605

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7910521A SE7910521L (sv) 1979-12-20 1979-12-20 Nya 2-metyl-6-substituerade-4-(2,3-disubstituerad fenyl)-1,4-dihydropyridin-3,5-diestrar med hypotesiva egenskaper, samt forfarande for deras framstellning, och farmaceutiska beredningar innehallande desamma

Country Status (11)

Country Link
EP (1) EP0031801A3 (xx)
JP (1) JPS56127356A (xx)
AU (1) AU6542380A (xx)
DD (1) DD155519A5 (xx)
DK (1) DK539980A (xx)
ES (4) ES8204720A1 (xx)
FI (1) FI803984L (xx)
MY (1) MY8500404A (xx)
NO (1) NO803856L (xx)
SE (1) SE7910521L (xx)
ZA (1) ZA807634B (xx)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3018259A1 (de) * 1980-05-13 1981-11-19 Bayer Ag, 5090 Leverkusen 1,4-dihydropyridine mit unterschiedlichen substituenten in 2- und 6-position, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln
DK161312C (da) * 1982-03-11 1991-12-09 Pfizer Analogifremgangsmaade til fremstilling af 2-aminoalkoxymethyl-4-phenyl-6-methyl-1,4-dihydropyridin-3,5-dicarboxylsyreestere eller syreadditionssalte deraf samt phthalimidoderivater til anvendelse som udgangsmateriale ved fremgangsmaaden
IL68604A0 (en) * 1982-05-21 1983-09-30 Haessle Ab Processes for preparing therapeutically active dihydropyridines and intermediates for the processes
DE3363743D1 (en) * 1982-07-22 1986-07-03 Pfizer Ltd Dihydropyridine anti-ischaemic and antihypertensive agents
HU192166B (en) * 1982-08-06 1987-05-28 Banyu Pharma Co Ltd Process for producing 2-carbamoyl-oxy-alkyl-1,4-dihydro-pyridine derivatives
EP0107293A3 (en) * 1982-09-04 1984-06-06 Pfizer Limited Dihydropyridines
PH19166A (en) * 1982-09-04 1986-01-16 Pfizer Dihydropyridined,pharmaceutical compositions and method of use
PT77842B (en) * 1982-12-21 1986-05-05 Pfizer Process for preparing dihydropyridines
US4515799A (en) * 1983-02-02 1985-05-07 Pfizer Inc. Dihydropyridine anti-ischaemic and antihypertensive agents
GB8306666D0 (en) * 1983-03-10 1983-04-13 Pfizer Ltd Therapeutic agents
GB8412208D0 (en) * 1984-05-12 1984-06-20 Pfizer Ltd Quinolone inotropic agents
GB8415386D0 (en) * 1984-06-15 1984-07-18 Pfizer Ltd Therapeutic agents
GB8526411D0 (en) * 1985-10-25 1985-11-27 Pfizer Ltd Dihydropyridines
GB8527698D0 (en) * 1985-11-09 1985-12-11 Pfizer Ltd Dihydropyridine antiischaemic & antihypertensive agents

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2117572C3 (de) * 1971-04-10 1980-03-20 Bayer Ag, 5090 Leverkusen Unsymmetrische 1,4-Dihydropyridin ^-dicarbonsäureester, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel
SE429652B (sv) * 1978-06-30 1983-09-19 Haessle Ab 2.6-dimetyl-4-(2.3-diklorfenyl)-1.4-dihydropyridin-3.5-dikarboxylsyra-3-metylester-5-etylester
CA1117117A (en) * 1978-10-10 1982-01-26 Fujisawa Pharmaceutical Co., Ltd. 2-methyl-dihydropyridine compound, processes for preparation thereof and pharmaceutical composition comprising the same

Also Published As

Publication number Publication date
ZA807634B (en) 1981-11-25
ES497927A0 (es) 1982-05-01
NO803856L (no) 1981-06-22
JPS56127356A (en) 1981-10-06
ES8306109A1 (es) 1982-10-01
FI803984L (fi) 1981-06-21
EP0031801A2 (en) 1981-07-08
ES508024A0 (es) 1982-11-16
AU6542380A (en) 1981-06-25
EP0031801A3 (en) 1981-09-16
DK539980A (da) 1981-06-21
ES508025A0 (es) 1982-11-01
ES8307221A1 (es) 1982-11-01
ES8204720A1 (es) 1982-05-01
ES508031A0 (es) 1982-10-01
ES8307220A1 (es) 1982-11-16
MY8500404A (en) 1985-12-31
DD155519A5 (de) 1982-06-16

Similar Documents

Publication Publication Date Title
SE7910521L (sv) Nya 2-metyl-6-substituerade-4-(2,3-disubstituerad fenyl)-1,4-dihydropyridin-3,5-diestrar med hypotesiva egenskaper, samt forfarande for deras framstellning, och farmaceutiska beredningar innehallande desamma
DE10199003I1 (de) Substituierte Thiazolidinionderivate
FI792058A (fi) Nya 2,6-dimetyl-4,2,3-disubstituerade fenyl-1,4-dihydropyridin-3,5-dikarboxylsyra-3,5-asymmetriska diestrar med blodtryckssaenkande egenskaper samt foerfarande foer framstaellning av dem och farmaceutiska preparat innehaollande desamma
FI904602A0 (fi) Pyrazoloderivat, foerfarande foer deras framstaellning och dessa innehaollande farmaceutiska blandningar.
DK163120C (da) Analogifremgangsmaade til fremstilling af substituerede acylderivater af 1,2,3,4-tetrahydroisoquinolin-3-carboxylsyre (s,s,s) eller et farmaceutisk acceptabelt salt deraf
FI950016A (fi) Heterosykliset yhdisteet lääkeaineena
DE69006984D1 (de) Thiazolidinedionederivate.
SE8005909L (sv) Heterocykliska foreningar och sett for deras framstellning samt fungicida eller vexttillvextreglerande kompositioner, innehallande sadana foreningar, jemte sett att bekempa svampsjukdomar eller reglera tillvexten av ...
ATE118487T1 (de) Thiazolidinedionederivate.
ES549542A0 (es) Un procedimiento para preparar nuevos derivados de benzo- triazol- y benzoxazolamina
NO903524D0 (no) Benzopyranforbindelser, fremgangsmaater ved fremstilling og farmasoeytiske blandinger derav.
RO93855A (ro) Procedeu pentru prepararea de arilciclobutilalchilamina
SE8403801L (sv) Nya bensotiazepiner med kardiovaskuler anvendbarhet, forfarande for framstellning derav och farmaceutiska kompositioner som innehaller dem
FI881816A (fi) Nya bicykliska foereningar, foerfarande foer deras framstaellning och dessa innehaollande farmaceutiska blandningar.
NL7612427A (nl) Werkwijze voor de bereiding van nieuwe chinoline- derivaten.
PT76614A (de) Thiomethylpyridin-derivate verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DK417380A (da) Analogifremgangsmaade til fremstilling af nitrosourinstofderivater eller syreadditionssalte deraf
GB1158632A (en) New Tri- and Tetrathiophosphate Esters
SE8105139L (sv) Karbamatderivat, insekticida, miticida eller nematocida kompositioner innehallande dessa samt forfarande for framstellning derav
JPS523031A (en) Novel tyrosinol derivatives
DK221786A (da) Phosphorimidater, deres fremstilling og anvendelse til bekaempelse af insekter, mider og nematoder
KR890002204A (ko) 신규의 디포스폰산 화합물 및 이들을 함유하는 제약 조성물

Legal Events

Date Code Title Description
NAV Patent application has lapsed

Ref document number: 7910521-9