NO803856L - 2-metyl-6-substituerte 4-(2,3-diklorfenyl-1,4-dihydropyridin)-3,5-dikarboksylsyre-3,5-diestere med hypotensive egenskaper, fremgangsmaate for deres fremstilling av farmasoeytiske preparater inneholdende disse - Google Patents

2-metyl-6-substituerte 4-(2,3-diklorfenyl-1,4-dihydropyridin)-3,5-dikarboksylsyre-3,5-diestere med hypotensive egenskaper, fremgangsmaate for deres fremstilling av farmasoeytiske preparater inneholdende disse

Info

Publication number
NO803856L
NO803856L NO803856A NO803856A NO803856L NO 803856 L NO803856 L NO 803856L NO 803856 A NO803856 A NO 803856A NO 803856 A NO803856 A NO 803856A NO 803856 L NO803856 L NO 803856L
Authority
NO
Norway
Prior art keywords
preparation
dichlorphenyl
dihydropyridine
diesters
substituted
Prior art date
Application number
NO803856A
Other languages
English (en)
Norwegian (no)
Inventor
Peder Bernhard Berntsson
Stig Aake Ingemar Carlsson
Jan Oernulf Gaarder
Bengt Richard Ljung
Original Assignee
Haessle Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Haessle Ab filed Critical Haessle Ab
Publication of NO803856L publication Critical patent/NO803856L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
NO803856A 1979-12-20 1980-12-18 2-metyl-6-substituerte 4-(2,3-diklorfenyl-1,4-dihydropyridin)-3,5-dikarboksylsyre-3,5-diestere med hypotensive egenskaper, fremgangsmaate for deres fremstilling av farmasoeytiske preparater inneholdende disse NO803856L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE7910521A SE7910521L (sv) 1979-12-20 1979-12-20 Nya 2-metyl-6-substituerade-4-(2,3-disubstituerad fenyl)-1,4-dihydropyridin-3,5-diestrar med hypotesiva egenskaper, samt forfarande for deras framstellning, och farmaceutiska beredningar innehallande desamma

Publications (1)

Publication Number Publication Date
NO803856L true NO803856L (no) 1981-06-22

Family

ID=20339605

Family Applications (1)

Application Number Title Priority Date Filing Date
NO803856A NO803856L (no) 1979-12-20 1980-12-18 2-metyl-6-substituerte 4-(2,3-diklorfenyl-1,4-dihydropyridin)-3,5-dikarboksylsyre-3,5-diestere med hypotensive egenskaper, fremgangsmaate for deres fremstilling av farmasoeytiske preparater inneholdende disse

Country Status (11)

Country Link
EP (1) EP0031801A3 (da)
JP (1) JPS56127356A (da)
AU (1) AU6542380A (da)
DD (1) DD155519A5 (da)
DK (1) DK539980A (da)
ES (4) ES8204720A1 (da)
FI (1) FI803984L (da)
MY (1) MY8500404A (da)
NO (1) NO803856L (da)
SE (1) SE7910521L (da)
ZA (1) ZA807634B (da)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3018259A1 (de) * 1980-05-13 1981-11-19 Bayer Ag, 5090 Leverkusen 1,4-dihydropyridine mit unterschiedlichen substituenten in 2- und 6-position, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln
DK161312C (da) * 1982-03-11 1991-12-09 Pfizer Analogifremgangsmaade til fremstilling af 2-aminoalkoxymethyl-4-phenyl-6-methyl-1,4-dihydropyridin-3,5-dicarboxylsyreestere eller syreadditionssalte deraf samt phthalimidoderivater til anvendelse som udgangsmateriale ved fremgangsmaaden
IL68604A0 (en) * 1982-05-21 1983-09-30 Haessle Ab Processes for preparing therapeutically active dihydropyridines and intermediates for the processes
DE3363743D1 (en) * 1982-07-22 1986-07-03 Pfizer Ltd Dihydropyridine anti-ischaemic and antihypertensive agents
HU192166B (en) * 1982-08-06 1987-05-28 Banyu Pharma Co Ltd Process for producing 2-carbamoyl-oxy-alkyl-1,4-dihydro-pyridine derivatives
EP0107293A3 (en) * 1982-09-04 1984-06-06 Pfizer Limited Dihydropyridines
PH19166A (en) * 1982-09-04 1986-01-16 Pfizer Dihydropyridined,pharmaceutical compositions and method of use
PT77842B (en) * 1982-12-21 1986-05-05 Pfizer Process for preparing dihydropyridines
US4515799A (en) * 1983-02-02 1985-05-07 Pfizer Inc. Dihydropyridine anti-ischaemic and antihypertensive agents
GB8306666D0 (en) * 1983-03-10 1983-04-13 Pfizer Ltd Therapeutic agents
GB8412208D0 (en) * 1984-05-12 1984-06-20 Pfizer Ltd Quinolone inotropic agents
GB8415386D0 (en) * 1984-06-15 1984-07-18 Pfizer Ltd Therapeutic agents
GB8526411D0 (en) * 1985-10-25 1985-11-27 Pfizer Ltd Dihydropyridines
GB8527698D0 (en) * 1985-11-09 1985-12-11 Pfizer Ltd Dihydropyridine antiischaemic & antihypertensive agents

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2117572C3 (de) * 1971-04-10 1980-03-20 Bayer Ag, 5090 Leverkusen Unsymmetrische 1,4-Dihydropyridin ^-dicarbonsäureester, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel
SE429652B (sv) * 1978-06-30 1983-09-19 Haessle Ab 2.6-dimetyl-4-(2.3-diklorfenyl)-1.4-dihydropyridin-3.5-dikarboxylsyra-3-metylester-5-etylester
CA1117117A (en) * 1978-10-10 1982-01-26 Fujisawa Pharmaceutical Co., Ltd. 2-methyl-dihydropyridine compound, processes for preparation thereof and pharmaceutical composition comprising the same

Also Published As

Publication number Publication date
SE7910521L (sv) 1981-06-21
ZA807634B (en) 1981-11-25
ES497927A0 (es) 1982-05-01
JPS56127356A (en) 1981-10-06
ES8306109A1 (es) 1982-10-01
FI803984L (fi) 1981-06-21
EP0031801A2 (en) 1981-07-08
ES508024A0 (es) 1982-11-16
AU6542380A (en) 1981-06-25
EP0031801A3 (en) 1981-09-16
DK539980A (da) 1981-06-21
ES508025A0 (es) 1982-11-01
ES8307221A1 (es) 1982-11-01
ES8204720A1 (es) 1982-05-01
ES508031A0 (es) 1982-10-01
ES8307220A1 (es) 1982-11-16
MY8500404A (en) 1985-12-31
DD155519A5 (de) 1982-06-16

Similar Documents

Publication Publication Date Title
FI871041A0 (fi) Menetelmä terapeuttisesti käyttökelpoisten 3,5-disubstituoitujen pyrokatekolijohdannaisten valmistamiseksi
NO905255L (no) Fremgangsmaate for fremstilling av heterocyklisk substituerte acylaminotiazoler.
NO174239C (no) Fremgangsmåte for fremstilling av et oralt, farmasöytisk preparat
NO871727D0 (no) Fremgangsmaate for fremstilling av nye kinolinderivater.
NO803856L (no) 2-metyl-6-substituerte 4-(2,3-diklorfenyl-1,4-dihydropyridin)-3,5-dikarboksylsyre-3,5-diestere med hypotensive egenskaper, fremgangsmaate for deres fremstilling av farmasoeytiske preparater inneholdende disse
DK259879A (da) Fremgangsmaade til fremstiliing af tetrahydropyridin-og piperidinerivater samt syreadditionssalte deraf
AR228475A1 (es) Procedimiento para la preparacion de nuevos derivados de n-omega-(4-(3-indolil)-piperidino)-alquil-benzoimidazolonas
BE880591A (fr) Nouvelles 1,4-dihydropyridines, leur preparation et leur application comme medicaments
DK149855C (da) Analogifremgangsmaade til fremstilling af 1,4-dihydropyridinderivater
DK130382A (da) Fremgangsmaade til fremstilling af quinolinderivater eller salte deraf
SE422577B (sv) Forfarande for framstellning av 3,4-dihydro-2(1h)-kinazolinonderivat
DK260579A (da) Fremgangsmaade til fremstilling af 14,15-methylenderivater af oestranraekken
DK162581A (da) Fr&mgangsmaade til fremstilling af substituerede 1,4-dihydropyridiner
DK375987A (da) Fremgangsmaade til fremstilling af cycloalkyl-sub-stituerede 4-pyridyl derivater
DK173379A (da) Fremgangsmaade til fremstilling af 6alfa-halogen-3-keto-delta 1,4-pregnadienderivater
NO872672D0 (no) Fremgangsmaate for fremstilling av kondenserte dihydropyridiner.
AR209672A1 (es) Procedimiento de preparacion de 4-(2-sustituido-3-piridil)-,3,5-dicarboalcoxi-2,-dimetil-1,4-dihidropiridinas
SE7700533L (sv) Forfarande for framstellning av 3,4-dihydro-2(1h)-kinazolinonderivat
FI891111A (fi) Menetelmä 1,4-dihydropyridiinijohdannaisten valmistamiseksi
NO158736C (no) Analogifremgangsmaate for fremstilling av tetrahydropyridinderivater.
DK558988A (da) Fremgangsmaade til fremstilling af 3,3-disubstituerede indoliner
AR229111A1 (es) Procedimiento para la preparacion de nicotinatos de 4-(fenilalquiloxi 4-sustituido)fenilalquilo
DK167680A (da) Fremgangsmaade til fremstilling af dihydropyridinderivater
NO881709D0 (no) Fremgangsmaate ved fremstilling av nye dihydropyridinderivater.
DK143279A (da) Fremgangsmaade til fremstilling af 4-substituerede 1,2-diphenyl-3,5-dioxopyrazolidiner mellemprodukter til udoevelse af fremgangsmaade til deres fremstilling