DK52784A - Aryloxy-n-(aminoalkyl)-1-pyrrolidin- og -piperidincarboxamider og -carbothioamider, isaer til brug i midler til styring af hjertearytmi - Google Patents
Aryloxy-n-(aminoalkyl)-1-pyrrolidin- og -piperidincarboxamider og -carbothioamider, isaer til brug i midler til styring af hjertearytmi Download PDFInfo
- Publication number
- DK52784A DK52784A DK52784A DK52784A DK52784A DK 52784 A DK52784 A DK 52784A DK 52784 A DK52784 A DK 52784A DK 52784 A DK52784 A DK 52784A DK 52784 A DK52784 A DK 52784A
- Authority
- DK
- Denmark
- Prior art keywords
- carbon atoms
- lower alkyl
- phenyl
- aminoalkyl
- aryloxy
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/12—Oxygen or sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/42—Oxygen atoms attached in position 3 or 5
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
- C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/557,885 US4547514A (en) | 1983-12-05 | 1983-12-05 | Aryloxy-N-(aminoalkyl)-1-pyrrolidine and piperidine carboxamides and carbothioamides having antiarrhythmic activity |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK52784D0 DK52784D0 (da) | 1984-02-06 |
| DK52784A true DK52784A (da) | 1985-06-06 |
Family
ID=24227270
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK52784A DK52784A (da) | 1983-12-05 | 1984-02-06 | Aryloxy-n-(aminoalkyl)-1-pyrrolidin- og -piperidincarboxamider og -carbothioamider, isaer til brug i midler til styring af hjertearytmi |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US4547514A (xx) |
| EP (1) | EP0147909B1 (xx) |
| JP (1) | JPS60123466A (xx) |
| KR (1) | KR900005133B1 (xx) |
| AT (1) | ATE48413T1 (xx) |
| AU (1) | AU572747B2 (xx) |
| CA (1) | CA1227797A (xx) |
| DE (1) | DE3480651D1 (xx) |
| DK (1) | DK52784A (xx) |
| ES (4) | ES8601876A1 (xx) |
| HU (1) | HU193719B (xx) |
| IL (1) | IL70823A (xx) |
| PH (1) | PH20831A (xx) |
| PT (1) | PT78090B (xx) |
| ZA (1) | ZA84697B (xx) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4812451A (en) * | 1984-10-19 | 1989-03-14 | A. H. Robins Company, Incorporated | 1-(aminoalkyl and aminoalkylamino)carbonyl and thiocarbonyl)-α,.alpha. |
| US4810703A (en) * | 1984-10-19 | 1989-03-07 | A. H. Robins Company, Incorporated | 1-((aminoalkyl and aminoalkylamino)carbonyl and thiocarbonyl)-alpha, alpha-diarylpyrrolidine, piperidine and homopiperidineacetamides and acetonitriles |
| US4812452A (en) * | 1984-10-19 | 1989-03-14 | A. H. Robins Company, Incorporated | 1-((aminoalkyl and aminoalkylamino) carbonyl and thiocarbonyl)-α,α-diarylpyrrolidine, piperidine and homopiperidineacetamides and acetonitriles |
| US5183902A (en) * | 1985-02-28 | 1993-02-02 | A. H. Robins Company, Incorporated | Method of treating muscular tension, muscle spasticity and anxiety with 3-aryloxy and 3-arylthioazetidinecarboxamides |
| US5151418A (en) * | 1985-02-28 | 1992-09-29 | A. H. Robins Company, Incorporated | Method of treating muscular tension, muscle spasticity and anxiety with 3-aryloxy and 3-arylthioazetidinecarboxamides |
| DE3800868A1 (de) * | 1988-01-14 | 1989-07-27 | Thomae Gmbh Dr K | Mittel zur behandlung von bradycardien und bradyarrhythmien |
| US5192776A (en) * | 1988-03-14 | 1993-03-09 | Hoechst-Roussel Pharmaceuticals Incorporated | 1-subsituted-4-pentafluorophenoxypiperidines |
| US5212184A (en) * | 1988-03-14 | 1993-05-18 | Hoechst-Roussel Pharmaceuticals Inc. | 1-substituted-4-pentafluorophenoxypiperidines |
| US8586571B2 (en) * | 2007-10-18 | 2013-11-19 | Takeda Pharmaceutical Company Limited | Heterocyclic compound |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2831862A (en) * | 1956-02-27 | 1958-04-22 | Lakeside Lab Inc | Ethers of n-alkyl-3-hydroxypiperidine and salts thereof |
| US3577415A (en) * | 1968-12-23 | 1971-05-04 | Robins Co Inc A H | 1-substituted-3-substituted phenoxypyrrolidines |
| US3577432A (en) * | 1968-12-23 | 1971-05-04 | Robins Co Inc A H | 1-substituted-3-phenoxypyrrolidines |
| FR2315274A1 (fr) * | 1975-06-27 | 1977-01-21 | Parcor | Nouveaux derives de la thieno (2,3-c) pyridine, leur preparation et leurs applications |
| US4036957A (en) * | 1975-11-18 | 1977-07-19 | A. H. Robins Company, Inc. | Phenoxy compounds in combinations to suppress gastric bleeding in aspirin therapy |
| MX6634E (es) * | 1979-01-09 | 1985-09-12 | Robins Co Inc A H | Procedimiento para preparar el isomero trans de 3-ariloxi-4-hidroxipirrolidinas |
-
1983
- 1983-12-05 US US06/557,885 patent/US4547514A/en not_active Expired - Fee Related
-
1984
- 1984-01-30 IL IL70823A patent/IL70823A/xx unknown
- 1984-01-30 ZA ZA84697A patent/ZA84697B/xx unknown
- 1984-02-01 AU AU23976/84A patent/AU572747B2/en not_active Ceased
- 1984-02-01 ES ES529364A patent/ES8601876A1/es not_active Expired
- 1984-02-06 DK DK52784A patent/DK52784A/da not_active Application Discontinuation
- 1984-02-09 PH PH30213A patent/PH20831A/en unknown
- 1984-02-10 PT PT78090A patent/PT78090B/pt not_active IP Right Cessation
- 1984-03-23 JP JP59055975A patent/JPS60123466A/ja active Pending
- 1984-05-10 KR KR1019840002526A patent/KR900005133B1/ko active IP Right Grant
- 1984-06-13 DE DE8484303995T patent/DE3480651D1/de not_active Expired - Fee Related
- 1984-06-13 EP EP84303995A patent/EP0147909B1/en not_active Expired
- 1984-06-13 AT AT84303995T patent/ATE48413T1/de not_active IP Right Cessation
- 1984-06-18 CA CA000456806A patent/CA1227797A/en not_active Expired
- 1984-12-04 HU HU844476A patent/HU193719B/hu not_active IP Right Cessation
-
1985
- 1985-06-14 ES ES544169A patent/ES8802021A1/es not_active Expired
-
1986
- 1986-06-02 ES ES555591A patent/ES8802572A1/es not_active Expired
- 1986-06-02 ES ES555590A patent/ES8802571A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| DE3480651D1 (de) | 1990-01-11 |
| EP0147909B1 (en) | 1989-12-06 |
| IL70823A (en) | 1987-10-20 |
| ES8802572A1 (es) | 1987-07-01 |
| JPS60123466A (ja) | 1985-07-02 |
| ES544169A0 (es) | 1987-01-16 |
| ES529364A0 (es) | 1985-11-16 |
| KR900005133B1 (ko) | 1990-07-20 |
| AU572747B2 (en) | 1988-05-12 |
| ES8802571A1 (es) | 1987-07-01 |
| ATE48413T1 (de) | 1989-12-15 |
| HU193719B (en) | 1987-11-30 |
| ES8601876A1 (es) | 1985-11-16 |
| PT78090B (en) | 1986-04-17 |
| ES555590A0 (es) | 1987-07-01 |
| PT78090A (en) | 1984-03-01 |
| PH20831A (en) | 1987-04-30 |
| US4547514A (en) | 1985-10-15 |
| ES555591A0 (es) | 1987-07-01 |
| EP0147909A1 (en) | 1985-07-10 |
| IL70823A0 (en) | 1984-04-30 |
| AU2397684A (en) | 1985-06-13 |
| KR850004959A (ko) | 1985-08-19 |
| ZA84697B (en) | 1984-09-26 |
| CA1227797A (en) | 1987-10-06 |
| HUT35648A (en) | 1985-07-29 |
| ES8802021A1 (es) | 1987-01-16 |
| DK52784D0 (da) | 1984-02-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AHB | Application shelved due to non-payment |