IL70823A - Pharmaceutical compositions containing aryloxy-n-(aminoalkyl)-1-pyrrolidine or-piperidine carboxamides - Google Patents

Pharmaceutical compositions containing aryloxy-n-(aminoalkyl)-1-pyrrolidine or-piperidine carboxamides

Info

Publication number
IL70823A
IL70823A IL70823A IL7082384A IL70823A IL 70823 A IL70823 A IL 70823A IL 70823 A IL70823 A IL 70823A IL 7082384 A IL7082384 A IL 7082384A IL 70823 A IL70823 A IL 70823A
Authority
IL
Israel
Prior art keywords
carbon atoms
lower alkyl
phenyl
aminoalkyl
pyrrolidine
Prior art date
Application number
IL70823A
Other languages
English (en)
Other versions
IL70823A0 (en
Original Assignee
Robins Co Inc A H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Robins Co Inc A H filed Critical Robins Co Inc A H
Publication of IL70823A0 publication Critical patent/IL70823A0/xx
Publication of IL70823A publication Critical patent/IL70823A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/12—Oxygen or sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/42—Oxygen atoms attached in position 3 or 5
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
IL70823A 1983-12-05 1984-01-30 Pharmaceutical compositions containing aryloxy-n-(aminoalkyl)-1-pyrrolidine or-piperidine carboxamides IL70823A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/557,885 US4547514A (en) 1983-12-05 1983-12-05 Aryloxy-N-(aminoalkyl)-1-pyrrolidine and piperidine carboxamides and carbothioamides having antiarrhythmic activity

Publications (2)

Publication Number Publication Date
IL70823A0 IL70823A0 (en) 1984-04-30
IL70823A true IL70823A (en) 1987-10-20

Family

ID=24227270

Family Applications (1)

Application Number Title Priority Date Filing Date
IL70823A IL70823A (en) 1983-12-05 1984-01-30 Pharmaceutical compositions containing aryloxy-n-(aminoalkyl)-1-pyrrolidine or-piperidine carboxamides

Country Status (15)

Country Link
US (1) US4547514A (xx)
EP (1) EP0147909B1 (xx)
JP (1) JPS60123466A (xx)
KR (1) KR900005133B1 (xx)
AT (1) ATE48413T1 (xx)
AU (1) AU572747B2 (xx)
CA (1) CA1227797A (xx)
DE (1) DE3480651D1 (xx)
DK (1) DK52784A (xx)
ES (4) ES529364A0 (xx)
HU (1) HU193719B (xx)
IL (1) IL70823A (xx)
PH (1) PH20831A (xx)
PT (1) PT78090B (xx)
ZA (1) ZA84697B (xx)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4810703A (en) * 1984-10-19 1989-03-07 A. H. Robins Company, Incorporated 1-((aminoalkyl and aminoalkylamino)carbonyl and thiocarbonyl)-alpha, alpha-diarylpyrrolidine, piperidine and homopiperidineacetamides and acetonitriles
US4812452A (en) * 1984-10-19 1989-03-14 A. H. Robins Company, Incorporated 1-((aminoalkyl and aminoalkylamino) carbonyl and thiocarbonyl)-α,α-diarylpyrrolidine, piperidine and homopiperidineacetamides and acetonitriles
US4812451A (en) * 1984-10-19 1989-03-14 A. H. Robins Company, Incorporated 1-(aminoalkyl and aminoalkylamino)carbonyl and thiocarbonyl)-α,.alpha.
US5151418A (en) * 1985-02-28 1992-09-29 A. H. Robins Company, Incorporated Method of treating muscular tension, muscle spasticity and anxiety with 3-aryloxy and 3-arylthioazetidinecarboxamides
US5183902A (en) * 1985-02-28 1993-02-02 A. H. Robins Company, Incorporated Method of treating muscular tension, muscle spasticity and anxiety with 3-aryloxy and 3-arylthioazetidinecarboxamides
DE3800868A1 (de) * 1988-01-14 1989-07-27 Thomae Gmbh Dr K Mittel zur behandlung von bradycardien und bradyarrhythmien
US5192776A (en) * 1988-03-14 1993-03-09 Hoechst-Roussel Pharmaceuticals Incorporated 1-subsituted-4-pentafluorophenoxypiperidines
US5212184A (en) * 1988-03-14 1993-05-18 Hoechst-Roussel Pharmaceuticals Inc. 1-substituted-4-pentafluorophenoxypiperidines
JP5374377B2 (ja) * 2007-10-18 2013-12-25 武田薬品工業株式会社 複素環化合物

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2831862A (en) * 1956-02-27 1958-04-22 Lakeside Lab Inc Ethers of n-alkyl-3-hydroxypiperidine and salts thereof
US3577432A (en) * 1968-12-23 1971-05-04 Robins Co Inc A H 1-substituted-3-phenoxypyrrolidines
US3577415A (en) * 1968-12-23 1971-05-04 Robins Co Inc A H 1-substituted-3-substituted phenoxypyrrolidines
FR2315274A1 (fr) * 1975-06-27 1977-01-21 Parcor Nouveaux derives de la thieno (2,3-c) pyridine, leur preparation et leurs applications
US4036957A (en) * 1975-11-18 1977-07-19 A. H. Robins Company, Inc. Phenoxy compounds in combinations to suppress gastric bleeding in aspirin therapy
MX6634E (es) * 1979-01-09 1985-09-12 Robins Co Inc A H Procedimiento para preparar el isomero trans de 3-ariloxi-4-hidroxipirrolidinas

Also Published As

Publication number Publication date
AU572747B2 (en) 1988-05-12
ES555591A0 (es) 1987-07-01
PT78090A (en) 1984-03-01
HUT35648A (en) 1985-07-29
CA1227797A (en) 1987-10-06
ES8601876A1 (es) 1985-11-16
DK52784A (da) 1985-06-06
JPS60123466A (ja) 1985-07-02
ES555590A0 (es) 1987-07-01
PH20831A (en) 1987-04-30
US4547514A (en) 1985-10-15
EP0147909A1 (en) 1985-07-10
IL70823A0 (en) 1984-04-30
DE3480651D1 (de) 1990-01-11
EP0147909B1 (en) 1989-12-06
ES8802571A1 (es) 1987-07-01
ES529364A0 (es) 1985-11-16
HU193719B (en) 1987-11-30
ES544169A0 (es) 1987-01-16
PT78090B (en) 1986-04-17
ZA84697B (en) 1984-09-26
ES8802572A1 (es) 1987-07-01
KR850004959A (ko) 1985-08-19
ATE48413T1 (de) 1989-12-15
KR900005133B1 (ko) 1990-07-20
DK52784D0 (da) 1984-02-06
AU2397684A (en) 1985-06-13
ES8802021A1 (es) 1987-01-16

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