DK492677A - Fremgangsmaade til fremstilling af substituerede benzam9der - Google Patents

Fremgangsmaade til fremstilling af substituerede benzam9der

Info

Publication number
DK492677A
DK492677A DK492677A DK492677A DK492677A DK 492677 A DK492677 A DK 492677A DK 492677 A DK492677 A DK 492677A DK 492677 A DK492677 A DK 492677A DK 492677 A DK492677 A DK 492677A
Authority
DK
Denmark
Prior art keywords
benzames
substituted
procedure
production
substituted benzames
Prior art date
Application number
DK492677A
Other languages
Danish (da)
English (en)
Inventor
M S Hadley
E A Watts
Original Assignee
Beecham Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group Ltd filed Critical Beecham Group Ltd
Publication of DK492677A publication Critical patent/DK492677A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D455/00Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
    • C07D455/02Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing not further condensed quinolizine ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D455/00Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
    • C07D455/03Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
    • C07D455/04Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing a quinolizine ring system condensed with only one six-membered carbocyclic ring, e.g. julolidine
    • C07D455/06Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing a quinolizine ring system condensed with only one six-membered carbocyclic ring, e.g. julolidine containing benzo [a] quinolizine ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nutrition Science (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK492677A 1976-11-05 1977-11-04 Fremgangsmaade til fremstilling af substituerede benzam9der DK492677A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB46105/76A GB1593146A (en) 1976-11-05 1976-11-05 Octahydro-quinolizinyl benzamide derivatives

Publications (1)

Publication Number Publication Date
DK492677A true DK492677A (da) 1978-05-06

Family

ID=10439866

Family Applications (1)

Application Number Title Priority Date Filing Date
DK492677A DK492677A (da) 1976-11-05 1977-11-04 Fremgangsmaade til fremstilling af substituerede benzam9der

Country Status (15)

Country Link
US (1) US4213983A (fr)
JP (1) JPS5359692A (fr)
AU (1) AU512082B2 (fr)
BE (1) BE860049A (fr)
CA (1) CA1083145A (fr)
CH (1) CH638520A5 (fr)
DE (1) DE2748260A1 (fr)
DK (1) DK492677A (fr)
FR (1) FR2370051A1 (fr)
GB (1) GB1593146A (fr)
IE (1) IE45833B1 (fr)
NL (1) NL7712203A (fr)
NZ (1) NZ185474A (fr)
SE (1) SE7712455L (fr)
ZA (1) ZA776129B (fr)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1118422A (fr) * 1978-11-20 1982-02-16 Herbert J. Havera Amido-hexahydrobenzo[a]quinolizines substituees en 2 et trans
IL59004A0 (en) * 1978-12-30 1980-03-31 Beecham Group Ltd Substituted benzamides their preparation and pharmaceutical compositions containing them
FR2476088A2 (fr) * 1979-01-16 1981-08-21 Delalande Sa Nouveaux derives du nor-tropane, leur procede de preparation et leur application en therapeutique
IL61642A0 (en) * 1979-12-20 1981-01-30 Beecham Group Ltd Aniline derivatives,their preparation and pharmalceutical compositions containing them
IL61972A0 (en) * 1980-01-30 1981-02-27 Beecham Group Ltd Azabicyclic compounds,their preparation and pharmaceutical compositions containing them
EP0036269A1 (fr) * 1980-03-15 1981-09-23 Beecham Group Plc Benzamides substitués
DK116181A (da) * 1980-04-11 1981-10-12 Hoffmann La Roche Fremgangsmaade til fremstilling af quinolizidinderivater
ZA815668B (en) * 1980-09-04 1982-08-25 Westinghouse Brake & Signal Swinging plug door
EP0047620B1 (fr) * 1980-09-10 1985-03-13 Beecham Group Plc Aryl amides diazabicycliques, procédé pour leur préparation et leur application
ZA818221B (en) * 1980-12-12 1982-10-27 Beecham Group Plc Pharmaceutical compounds
EP0057536A1 (fr) * 1981-01-26 1982-08-11 Beecham Group Plc Composés à activité pharmaceutique
US4409225A (en) * 1981-03-16 1983-10-11 Beecham Group Limited Substituted benzamides
EP0067565A1 (fr) * 1981-06-16 1982-12-22 Beecham Group Plc Benzamides bicycliques, leur procédé de préparation et leur application
EP0068699A1 (fr) * 1981-06-22 1983-01-05 Beecham Group Plc Décahydroquinolylbenzamides, leur procédé de préparation, et les compositions pharmaceutiques les contenant
CA1183847A (fr) * 1981-10-01 1985-03-12 Georges Van Daele N-(3-hydroxy-4-piperidinyl)benzamide; derives
IE56226B1 (en) * 1982-04-14 1991-05-22 Beecham Group Plc Substituted azabicyclo compounds,process for their preparation and pharmaceutical compositions containing them
ZA832549B (en) * 1982-04-14 1988-09-28 Beecham Group Plc Pharmaceutically active compounds
EP0094744A1 (fr) * 1982-04-23 1983-11-23 Beecham Group Plc Azabicyclobenzamides, leur préparation et leurs compositions pharmaceutiques
FR2531083B1 (fr) * 1982-06-29 1986-11-28 Sandoz Sa Nouveaux derives de la piperidine, leur preparation et leur utilisation comme medicaments
JPS5936675A (ja) * 1982-07-13 1984-02-28 サンド・アクチエンゲゼルシヤフト 二環性複素環式カルボン酸アザビシクロアルキルエステルまたはアミド
JPS5946281A (ja) * 1982-09-09 1984-03-15 Suntory Ltd 1置換ピロリチジン誘導体およびその用途
DE3429830A1 (de) * 1983-08-26 1985-03-07 Sandoz-Patent-GmbH, 7850 Lörrach Automatische carbonsaeure- und sulfonsaeureester oder -amide
FR2557110B1 (fr) * 1983-12-23 1989-11-24 Sandoz Sa Nouveaux derives d'amines cycliques, leur preparation et leur utilisation comme medicaments
NL8500370A (nl) * 1984-02-22 1985-09-16 Sandoz Ag Diazepinoindolen, werkwijzen voor hun bereiding en farmaceutische preparaten die ze bevatten.
JPS60184079A (ja) * 1984-02-29 1985-09-19 Suntory Ltd ピロリチジン誘導体
US4605652A (en) * 1985-02-04 1986-08-12 A. H. Robins Company, Inc. Method of enhancing memory or correcting memory deficiency with arylamido (and arylthioamido)-azabicycloalkanes
GB8523211D0 (en) * 1985-09-19 1985-10-23 Beecham Group Plc Compounds
GB8525844D0 (en) * 1985-10-19 1985-11-20 Beecham Group Plc Compounds
ES2044964T3 (es) * 1986-08-12 1994-01-16 Roussel Uclaf Procedimiento para preparar derivados de decahidroquinolina.
US4863919A (en) * 1988-02-01 1989-09-05 A. H. Robins Company, Incorporated Method of enhancing memory or correcting memory deficiency with arylamido(and arylthiomido)-azabicycloalkanes
US5126343A (en) * 1989-09-11 1992-06-30 G. D. Searle & Co. N-azabicyclo [3.3.0]octane amides of aromatic acids
US4992461A (en) * 1989-09-11 1991-02-12 G. D. Searle & Co. N-azabicyclo(3.3.0)octane amides of aromatic acids, compositions, and methods of use thereof
US5039528A (en) * 1989-12-11 1991-08-13 Olney John W EAA antagonists as anti-emetic drugs
JP2529912B2 (ja) * 1990-10-16 1996-09-04 帝国化学産業株式会社 ベンズアミド誘導体
IL100432A (en) * 1990-12-27 1996-01-19 Erba Carlo Spa Dihydrobenzopuran carboxamides, their preparation and pharmaceutical preparations containing them
US5516782A (en) * 1991-03-07 1996-05-14 G. D. Searle & Co. New meso-azacyclic aromatic acid amides and esters as novel serotonergic agents
AU1578692A (en) * 1991-03-07 1992-10-06 G.D. Searle & Co. New meso-azacyclic aromatic acid amides and esters as novel serotonergic agents
FR2676448B1 (fr) * 1991-05-14 1995-01-20 Adir Nouveaux derives amidiques de 1-amino octahydropyrido [2,1-c] [1,4] oxazine, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent.
US5852014A (en) * 1992-03-12 1998-12-22 Smithkline Beecham P.L.C. Condensed indole derivatives as 5HT4 -receptor antagonists
US5244907A (en) * 1992-03-26 1993-09-14 A. H. Robins Company, Incorporated Carbocyclic carboxylic acid amides and esters of azabicyclic compounds as gastric prokinetic, antiemetic, anxiolytic and antiarrhythmic agents
US5190953A (en) * 1992-03-26 1993-03-02 A. H. Robins Company, Incorporated Heterocyclic carboxylic acid amides and esters of azabicyclic compounds as gastric prokinetic, antiemetic, anxiolytic and antiarrhythmic agents
ES2296910T3 (es) * 2001-01-22 2008-05-01 Sankyo Company, Limited Compuestos sustituidos con grupo amino biciclicos.
US8546377B2 (en) * 2009-04-23 2013-10-01 Abbvie Inc. Modulators of 5-HT receptors and methods of use thereof
US8518933B2 (en) * 2009-04-23 2013-08-27 Abbvie Inc. Modulators of 5-HT receptors and methods of use thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3176017A (en) * 1963-02-26 1965-03-30 American Home Prod Aroylalkyl derivatives of diazabicyclo-nonanes and-decanes
FR1407055A (fr) * 1963-03-05 1965-07-30 Ile De France Nouveau procédé de préparation de benzamides substitués
US3452025A (en) * 1966-08-12 1969-06-24 Warner Lambert Pharmaceutical 1-amino-1,3,4,6,7,11b-hexahydro-2h-benzo(a) quinolizines
CA940930A (en) 1969-12-22 1974-01-29 John W. Van Dyke 2-substituted aminohexahydrobenzo (a) quinolizine derivatives
US3692791A (en) * 1970-05-18 1972-09-19 American Home Prod SUBSTITUTED 2-t-BUTYL-OCTAHYDRO-2H-QUINOLIZINES
DE2037611A1 (de) * 1970-07-29 1972-02-03 Farbenfabriken Bayer Ag, 5090 Leverkusen Verfahren zur Verwertung von Abfall-Salpetersäure
US3966957A (en) * 1972-04-03 1976-06-29 A. H. Robins Company, Incorporated Method for controlling emesis with N-(1-substituted-3-pyrrolidinyl)benzamides and thiobenzamides
DE2513136C3 (de) * 1974-03-21 1981-04-30 Anphar S.A., Madrid N-(1-Benzylpiperid-4-yl)-benzamide, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Präparate

Also Published As

Publication number Publication date
JPS5359692A (en) 1978-05-29
JPS6129356B2 (fr) 1986-07-05
IE45833L (en) 1978-05-05
NZ185474A (en) 1980-10-08
BE860049A (fr) 1978-04-24
NL7712203A (nl) 1978-05-09
GB1593146A (en) 1981-07-15
ZA776129B (en) 1978-06-28
FR2370051A1 (fr) 1978-06-02
AU2975377A (en) 1979-04-26
AU512082B2 (en) 1980-09-25
DE2748260A1 (de) 1978-05-11
IE45833B1 (en) 1982-12-15
CH638520A5 (de) 1983-09-30
CA1083145A (fr) 1980-08-05
SE7712455L (sv) 1978-05-06
FR2370051B1 (fr) 1981-05-22
US4213983A (en) 1980-07-22

Similar Documents

Publication Publication Date Title
DK492677A (da) Fremgangsmaade til fremstilling af substituerede benzam9der
DK30277A (da) Fremgangsmade til fremstilling af substituerede phenylamidiner
DK149062C (da) Analogifremgangsmaade til fremstilling af cefuroximestere
DK207178A (da) Fremgangsmaade til fremstilling af sojaskraa
DK354678A (da) Fremgangsmaade til fremstilling af propenylaminer
DK446277A (da) Fremgangsmaade til fremstilling af orthoeddikesyrealkylestere
DK452578A (da) Fremgangsmaade til fremstilling af furanderivater
DK476277A (da) Fremgangsmaade til fremstilling af krydslaminater
DK144377A (da) Fremgangsmade til fremstilling af acylcyanider
DK476377A (da) Fremgangsmaade til fremstilling af krydslaminater
DK88777A (da) Fremgangsmade til fremstilling af substituerede azapuriner
DK97877A (da) Fremgangsmade til fremstilling af urinstofderivater
DK377978A (da) Fremgangsmaade til fremstilling af opskummede plaststoffer
DK192778A (da) Fremgangsmaade til fremstilling af bisamidiner
DK575576A (da) Fremgangsmade til fremstilling af krystallinske former af natrium-cefamandol
DK271377A (da) Fremgangsmade til fremstilling af substituerede arylacetamidocephalosporiner
DK87977A (da) Fremgangsmade til fremstilling af benzylestere
DK144277A (da) Fremgangsmade til fremstilling af acylcyanider
DK73977A (da) Fremgangsmade til fremstilling af d-homosteroider
DK417477A (da) Fremgangsmaade til fremstilling af urethaner
DK551677A (da) Fremgangsmaade til fremstilling af prostaglandinanaloge
DK379277A (da) Fremgangsmaade til fremstilling af prostaglandinanaloge
DK77179A (da) Fremgangsmaade til fremstilling af androstadiener
DK148775C (da) Fremgangsmaade til fremstilling af oelurt
DK575277A (da) Fremgangsmaade til fremstilling af basisk substituerede 0-propyloximer

Legal Events

Date Code Title Description
AHB Application shelved due to non-payment