US5972682A
(en)
*
|
1984-05-29 |
1999-10-26 |
Genencor International, Inc. |
Enzymatically active modified subtilisins
|
US5013657A
(en)
*
|
1988-04-12 |
1991-05-07 |
Bryan Philip N |
Subtilisin mutations
|
US4990452A
(en)
*
|
1986-02-12 |
1991-02-05 |
Genex Corporation |
Combining mutations for stabilization of subtilisin
|
JPS63502959A
(ja)
*
|
1986-02-12 |
1988-11-02 |
ジェネックス、コ−ポレ−ション |
突然変異誘発及びスクリ−ニング方法並びに生成物
|
SG30639G
(en)
*
|
1986-04-30 |
1995-09-01 |
Genencor Int |
Non-human carbonyl hydrolase mutants DNA sequences and vectors encoding same and hosts transformed with said vectors
|
HUT50877A
(en)
*
|
1987-02-27 |
1990-03-28 |
Gist Brocades Nv |
Process for producing stable gene amplification in chromosomal dna of procaryote microorganisms
|
BR8805647A
(pt)
*
|
1987-02-27 |
1989-10-31 |
Gist Brocades Nv |
Processo para clonagem molecular e expressao de genes que codificam para enzimas proteoliticas
|
EP0896062A3
(en)
*
|
1987-02-27 |
1999-04-07 |
Genencor International, Inc. |
Transformation of alkalophilic bacillus strains
|
JPH01137972A
(ja)
*
|
1987-08-03 |
1989-05-30 |
Ajinomoto Co Inc |
新規サチライシン
|
US4865983A
(en)
*
|
1987-12-04 |
1989-09-12 |
W. R. Grace & Co.-Conn. |
Cleaning compositions containing protease produced by vibrio and method of use
|
DK6488D0
(da)
*
|
1988-01-07 |
1988-01-07 |
Novo Industri As |
Enzymer
|
CN1056187C
(zh)
*
|
1988-02-11 |
2000-09-06 |
金克克国际有限公司 |
新的蛋白水解酶及其在洗涤剂中的应用
|
US6287841B1
(en)
|
1988-02-11 |
2001-09-11 |
Genencor International, Inc. |
High alkaline serine protease
|
US5324653A
(en)
*
|
1988-02-11 |
1994-06-28 |
Gist-Brocades N.V. |
Recombinant genetic means for the production of serine protease muteins
|
CA1333777C
(en)
*
|
1988-07-01 |
1995-01-03 |
Randy M. Berka |
Aspartic proteinase deficient filamentous fungi
|
US5122449A
(en)
*
|
1988-10-07 |
1992-06-16 |
Eastman Kodak Company |
Use of a protease in the extraction of chlamydial, gonococcal and herpes antigens
|
JPH03505976A
(ja)
*
|
1989-05-17 |
1991-12-26 |
アムジエン・インコーポレーテツド |
多重突然変異スブチリシン
|
US5665587A
(en)
*
|
1989-06-26 |
1997-09-09 |
Novo Nordisk A/S |
Modified subtilisins and detergent compositions containing same
|
US5658871A
(en)
*
|
1989-07-07 |
1997-08-19 |
Lever Brothers Company, Division Of Conopco, Inc. |
Microbial lipase muteins and detergent compositions comprising same
|
US6271012B1
(en)
*
|
1989-10-11 |
2001-08-07 |
Genencor International, Inc. |
Protease muteins and their use in detergents
|
US5482849A
(en)
*
|
1990-12-21 |
1996-01-09 |
Novo Nordisk A/S |
Subtilisin mutants
|
GB9027836D0
(en)
*
|
1990-12-21 |
1991-02-13 |
Unilever Plc |
Enzymes and enzymatic detergent compositions
|
US5340735A
(en)
|
1991-05-29 |
1994-08-23 |
Cognis, Inc. |
Bacillus lentus alkaline protease variants with increased stability
|
US6436690B1
(en)
|
1993-09-15 |
2002-08-20 |
The Procter & Gamble Company |
BPN′ variants having decreased adsorption and increased hydrolysis wherein one or more loop regions are substituted
|
US6440717B1
(en)
|
1993-09-15 |
2002-08-27 |
The Procter & Gamble Company |
BPN′ variants having decreased adsorption and increased hydrolysis
|
US6599730B1
(en)
|
1994-05-02 |
2003-07-29 |
Procter & Gamble Company |
Subtilisin 309 variants having decreased adsorption and increased hydrolysis
|
US6455295B1
(en)
|
1995-03-08 |
2002-09-24 |
The Procter & Gamble Company |
Subtilisin Carlsberg variants having decreased adsorption and increased hydrolysis
|
IL117350A0
(en)
|
1995-03-09 |
1996-07-23 |
Procter & Gamble |
Proteinase k variants having decreased adsorption and increased hydrolysis
|
US6475765B1
(en)
|
1995-03-09 |
2002-11-05 |
Procter & Gamble Company |
Subtilisin DY variants having decreased adsorption and increased hydrolysis
|
CA2270593C
(en)
|
1996-11-04 |
2005-06-07 |
Novo Nordisk A/S |
Subtilase variants and compositions
|
KR100591553B1
(ko)
|
1996-11-04 |
2006-06-19 |
노보자임스 에이/에스 |
섭틸라제 변종과 조성물
|
JP2001514846A
(ja)
|
1997-08-29 |
2001-09-18 |
ノボ ノルディスク アクティーゼルスカブ |
プロテアーゼ変異体及び組成物
|
CN1148444C
(zh)
|
1997-08-29 |
2004-05-05 |
诺沃奇梅兹有限公司 |
蛋白酶变体及组合物
|
US6780629B2
(en)
|
1997-11-21 |
2004-08-24 |
Novozymes A/S |
Subtilase enzymes
|
EP1032655B1
(en)
|
1997-11-21 |
2005-06-29 |
Novozymes A/S |
Protease variants and compositions
|
US6773907B2
(en)
|
1997-11-21 |
2004-08-10 |
Peter Kamp Hansen |
Subtilase enzymes
|
CA2325568A1
(en)
|
1998-03-26 |
1999-09-30 |
The Procter & Gamble Company |
Serine protease variants having amino acid substitutions
|
US6908757B1
(en)
|
1998-03-26 |
2005-06-21 |
The Procter & Gamble Company |
Serine protease variants having amino acid deletions and substitutions
|
US6495136B1
(en)
|
1998-03-26 |
2002-12-17 |
The Procter & Gamble Company |
Proteases having modified amino acid sequences conjugated to addition moieties
|
EP1803817B1
(en)
|
1998-12-18 |
2011-04-06 |
Novozymes A/S |
Subtilase enzymes of the I-S1 and I-S2 sub-groups having an additional amino acid residue in an active site loop region
|
DE60040284D1
(de)
|
1999-05-20 |
2008-10-30 |
Novozymes As |
Subtilase enzyme der i-s1 und i-s2 untergruppen mit mindestens einer zusätzlichen aminosäure zwischen position 129 und 130
|
AU4393100A
(en)
|
1999-05-20 |
2000-12-12 |
Novozymes A/S |
Subtilase enzymes of the i-s1 and i-s2 sub-groups having at least one additionalamino acid residue between positions 125 and 126
|
AU4392900A
(en)
|
1999-05-20 |
2000-12-12 |
Novozymes A/S |
Subtilase enzymes of the i-s1 and i-s2 sub-groups having at least one additionalamino acid residue between positions 127 and 128
|
ATE407201T1
(de)
|
1999-05-20 |
2008-09-15 |
Novozymes As |
Subtilase-enzyme der i-s1 und i-s2 untergruppen mit wenigstens einem zusätzlichen aminosäurerest zwischen positionen 126 und 127
|
DE60040282D1
(de)
|
1999-05-20 |
2008-10-30 |
Novozymes As |
SUBTILASE ENZYME DER I-S1 UND I-S2 UNTERGRUPPEN MIT MINDESTENS EINER ZUSäTZLICHEN AMINOSäURE ZWISCHEN POSITION 132 UND 133
|
EP1183342B2
(en)
|
1999-05-20 |
2012-06-13 |
Novozymes A/S |
Subtilase enzymes of the i-s1 and i-s2 sub-groups having at least one additional amino acid residue between positions 128 and 129
|
US6946128B1
(en)
|
1999-07-22 |
2005-09-20 |
The Procter & Gamble Company |
Protease conjugates having sterically protected epitope regions
|
AU5928400A
(en)
|
1999-07-22 |
2001-02-13 |
Procter & Gamble Company, The |
Protease conjugates having sterically protected clip sites
|
WO2001007575A2
(en)
*
|
1999-07-22 |
2001-02-01 |
The Procter & Gamble Company |
Subtilisin protease variants having amino acid deletions and substitutions in defined epitope regions
|
CA2376045A1
(en)
|
1999-07-22 |
2001-02-01 |
The Procter & Gamble Company |
Subtilisin protease variants having amino acid substitutions in defined epitope regions
|
US6727085B2
(en)
|
1999-12-15 |
2004-04-27 |
Fanoe Tina Sejersgaard |
Subtilase variants having an improved wash performance on egg stains
|
US6777218B1
(en)
|
2000-03-14 |
2004-08-17 |
Novozymes A/S |
Subtilase enzymes having an improved wash performance on egg stains
|
WO2002010183A1
(en)
*
|
2000-07-31 |
2002-02-07 |
Menzel, Rolf |
Compositions and methods for directed gene assembly
|
US7314745B2
(en)
*
|
2001-03-02 |
2008-01-01 |
Seiren Kabushiki Kaisha |
Protein and DNA encoding the same
|
EP1530631B1
(en)
*
|
2002-01-16 |
2013-08-07 |
Genencor International, Inc. |
Multiply-substituted protease variants
|
EP2339016B8
(en)
|
2002-03-29 |
2016-01-27 |
Danisco US Inc. |
Enhanced production of subtilisins in Bacillus
|
AU2003275473A1
(en)
|
2002-10-08 |
2004-05-04 |
Genencor International, Inc. |
Phenolic binding peptides
|
CA2526341C
(en)
|
2003-05-07 |
2013-02-19 |
Novozymes A/S |
Variant subtilisin enzymes (subtilases)
|
ATE516347T1
(de)
|
2003-10-23 |
2011-07-15 |
Novozymes As |
Protease mit verbesserter stabilität in detergentien
|
EP1735339A2
(en)
*
|
2004-04-09 |
2006-12-27 |
Genencor International, Inc. |
Pcka modifications and enhanced protein expression in bacillus
|
KR100750659B1
(ko)
|
2005-02-18 |
2007-08-20 |
인하대학교 산학협력단 |
계면활성제 및 산화제에 매우 안정한 호염, 호알카리성 단백질 분해효소 및 이를 암호화하는 유전자
|
US20100029538A1
(en)
|
2006-04-14 |
2010-02-04 |
Anna-Liisa Auterinen |
One-Step Treatment of Textiles
|
CN101460618A
(zh)
|
2006-04-20 |
2009-06-17 |
诺维信公司 |
对蛋渍具有改进的洗涤性能的洒维奈斯变体
|
US20080090745A1
(en)
*
|
2006-10-13 |
2008-04-17 |
Fox Bryan P |
Expression of Streptomyces subtilism inhibitor (SSI) proteins in Bacillus and Streptomyces sp.
|
AU2008226792B2
(en)
|
2007-03-12 |
2013-06-06 |
Danisco Us Inc. |
Modified proteases
|
EP2147098B1
(en)
|
2007-04-30 |
2013-07-17 |
Danisco US Inc. |
Use of protein hydrolysates to stabilize metalloprotease detergent formulations
|
US8343735B2
(en)
*
|
2007-05-10 |
2013-01-01 |
Danisco Us Inc. |
Modified secretion system to increase expression of polypeptides in bacteria
|
SG148934A1
(en)
|
2007-06-11 |
2009-01-29 |
Novozymes As |
A process for combined biopolishing and bleach clean-up
|
JP5629584B2
(ja)
|
2007-12-21 |
2014-11-19 |
ダニスコ・ユーエス・インク |
バチルス内での促進されたタンパク質生成
|
AU2009228165B2
(en)
*
|
2008-03-28 |
2015-08-13 |
Danisco Us Inc. |
Method for amplifying locus in bacterial cell
|
AR076941A1
(es)
|
2009-06-11 |
2011-07-20 |
Danisco Us Inc |
Cepa de bacillus para una mayor produccion de proteina
|
WO2012022777A1
(en)
|
2010-08-19 |
2012-02-23 |
Novozymes A/S |
Induced sporulation screening method
|
CN106068273B
(zh)
|
2013-12-31 |
2021-01-08 |
丹尼斯科美国公司 |
增强的蛋白质表达
|
KR102588719B1
(ko)
|
2014-12-16 |
2023-10-12 |
다니스코 유에스 인크. |
향상된 단백질 발현
|
WO2016100128A1
(en)
|
2014-12-19 |
2016-06-23 |
Danisco Us Inc |
Enhanced protein expression
|
EP4353828A2
(en)
|
2017-02-24 |
2024-04-17 |
Danisco US Inc. |
Compositions and methods for increased protein production in bacillus licheniformis
|
WO2019040412A1
(en)
|
2017-08-23 |
2019-02-28 |
Danisco Us Inc |
METHODS AND COMPOSITIONS FOR EFFICIENT GENETIC MODIFICATION OF BACILLUS LICHENIFORMIS STRAINS
|
WO2019055261A1
(en)
|
2017-09-13 |
2019-03-21 |
Danisco Us Inc |
MODIFIED 5 'NON-TRANSLATED REGION (UTR) SEQUENCES FOR INCREASED PROTEIN PRODUCTION IN BACILLUS
|
WO2019089898A1
(en)
|
2017-11-02 |
2019-05-09 |
Danisco Us Inc |
Freezing point depressed solid matrix compositions for melt granulation of enzymes
|
EP3735478B1
(en)
|
2018-01-03 |
2023-08-16 |
Danisco US Inc. |
Mutant and genetically modified bacillus cells and methods thereof for increased protein production
|
WO2020099490A1
(en)
|
2018-11-14 |
2020-05-22 |
Novozymes A/S |
Oral care composition comprising enzymes
|
CN110734903B
(zh)
*
|
2019-11-18 |
2021-06-04 |
山东隆科特酶制剂有限公司 |
一种生产耐高温中性蛋白酶的方法
|
JP2023524334A
(ja)
|
2020-01-15 |
2023-06-12 |
ダニスコ・ユーエス・インク |
バチルス・リケニフォルミス(bacillus licheniformis)における強化したタンパク質産生のための組成物及び方法
|
EP4199897A2
(en)
|
2020-08-24 |
2023-06-28 |
Novozymes A/S |
Oral care composition comprising a fructanase
|
CN117881772A
(zh)
|
2021-08-20 |
2024-04-12 |
丹尼斯科美国公司 |
编码新型核酸酶的多核苷酸、其组合物及其从蛋白质制剂中消除dna的方法
|
CN116286565B
(zh)
*
|
2022-07-12 |
2024-06-11 |
湖北佶凯星生物科技有限公司 |
一株高产碱性蛋白酶的枯草芽孢杆菌菌株及其应用
|