DK468186A - Polyxygenerede labdan-derivater, deres fremstilling og anvendelse - Google Patents
Polyxygenerede labdan-derivater, deres fremstilling og anvendelse Download PDFInfo
- Publication number
- DK468186A DK468186A DK468186A DK468186A DK468186A DK 468186 A DK468186 A DK 468186A DK 468186 A DK468186 A DK 468186A DK 468186 A DK468186 A DK 468186A DK 468186 A DK468186 A DK 468186A
- Authority
- DK
- Denmark
- Prior art keywords
- polyxygenerated
- preparation
- application
- derivatives
- labdan
- Prior art date
Links
- 206010006482 Bronchospasm Diseases 0.000 abstract 1
- 208000010412 Glaucoma Diseases 0.000 abstract 1
- 206010020751 Hypersensitivity Diseases 0.000 abstract 1
- 206010020772 Hypertension Diseases 0.000 abstract 1
- 230000007815 allergy Effects 0.000 abstract 1
- 125000000266 alpha-aminoacyl group Chemical group 0.000 abstract 1
- 230000007885 bronchoconstriction Effects 0.000 abstract 1
- 230000000747 cardiac effect Effects 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000002955 immunomodulating agent Substances 0.000 abstract 1
- 229940121354 immunomodulator Drugs 0.000 abstract 1
- 150000001761 labdane diterpenoid derivatives Chemical class 0.000 abstract 1
- 230000000144 pharmacologic effect Effects 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/78—Ring systems having three or more relevant rings
- C07D311/92—Naphthopyrans; Hydrogenated naphthopyrans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
- C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
- C07D473/08—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 1 and 3, e.g. theophylline
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Ophthalmology & Optometry (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pulmonology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Saccharide Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyrane Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19853535086 DE3535086A1 (de) | 1985-10-02 | 1985-10-02 | Neue polyoxygenierte labdan-derivate, verfahren zu ihrer herstellung und ihre anwendung als medikamente |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK468186D0 DK468186D0 (da) | 1986-10-01 |
| DK468186A true DK468186A (da) | 1987-04-03 |
Family
ID=6282512
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK468186A DK468186A (da) | 1985-10-02 | 1986-10-01 | Polyxygenerede labdan-derivater, deres fremstilling og anvendelse |
Country Status (14)
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4963537A (en) * | 1985-03-01 | 1990-10-16 | Hoechst-Roussel Pharmaceuticals Inc. | Labdane compounds, pharmaceutical compositions and use |
| DE3678736D1 (de) * | 1985-03-01 | 1991-05-23 | Hoechst Roussel Pharma | Labdanderivate, verfahren zu deren herstellung und deren verwendung als arzneimittel. |
| JPS6310783A (ja) * | 1985-11-15 | 1988-01-18 | Nippon Kayaku Co Ltd | 新規フオルスコリン誘導体 |
| AU591196B2 (en) * | 1985-11-15 | 1989-11-30 | Nippon Kayaku Kabushiki Kaisha | Novel forskolin derivatives |
| DE3623300A1 (de) * | 1986-07-11 | 1988-01-21 | Hoechst Ag | 7-acyloxy-6-aminoacyloxypolyoxylabdane, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
| US5646175A (en) * | 1987-12-28 | 1997-07-08 | Hoechst Marion Roussel, Inc. | Carbamoyloxylabdane compounds |
| US4920146A (en) * | 1986-12-29 | 1990-04-24 | Hoechst Roussel Pharmaceuticals Inc. | Carbamoyloxylabdane compounds useful in reducing intraocular pressure |
| IN166900B (enrdf_load_stackoverflow) * | 1987-06-03 | 1990-08-04 | Hoechst India | |
| JPH0684367B2 (ja) * | 1987-06-29 | 1994-10-26 | 日本化薬株式会社 | フオルスコリン誘導体の新規製造法 |
| JP2504934B2 (ja) * | 1987-06-29 | 1996-06-05 | 日本化薬株式会社 | １，６，７−トリアシルフオルスコリン誘導体 |
| US5846992A (en) * | 1987-10-08 | 1998-12-08 | Hoechst Marion Roussel, Inc. | Synergistic intraocular pressure lowering combinations |
| US4902696A (en) * | 1987-10-08 | 1990-02-20 | Hoechst-Roussel Pharmaceuticals, Inc. | Synergistic intraocular pressure lowering combinations |
| US4883793A (en) * | 1988-05-09 | 1989-11-28 | Hoechst-Roussel Pharmaceuticals Inc. | Hydrazinocarbonyloxylabdanes for treating cardiac failure |
| EP0447962A1 (en) * | 1990-03-17 | 1991-09-25 | Hoechst Aktiengesellschaft | Labdanes and process for their preparation |
| YU128291A (sh) * | 1990-07-24 | 1994-09-09 | Joechst Aktiengesellschaft | Postpak za dobijanje 6-(3-substituisanih aminopropionil) 7-deacetilforskolinskih derivata |
| JP3557095B2 (ja) * | 1998-04-20 | 2004-08-25 | 高砂香料工業株式会社 | メラニン産生抑制剤 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2557784C2 (de) | 1975-12-22 | 1986-04-17 | Hoechst Ag, 6230 Frankfurt | Forskolin, Verfahren zu dessen Gewinnung und diese Verbindung enthaltende pharmazeutische Präparate |
| DE2640275A1 (de) | 1976-09-08 | 1978-03-09 | Hoechst Ag | Pharmakologisch wirksame substanz aus labiaten |
| DE2654796A1 (de) * | 1976-12-03 | 1978-06-08 | Hoechst Ag | Polyoxygenierte labdan-derivate |
| FR2460397A1 (fr) * | 1979-07-05 | 1981-01-23 | Ducellier & Cie | Demarreur electrique pour moteurs a combustion interne notamment de vehicules automobiles |
| DE3502685A1 (de) | 1985-01-26 | 1986-09-04 | Hoechst Ag, 6230 Frankfurt | Forskolin, seine analoge und derivate, verfahren zu deren herstellung mittels mikrobieller umwandlungen und die anwendung dieser verbindungen als arzneimittel |
| DE3581725D1 (de) * | 1984-12-14 | 1991-03-14 | Hoechst Roussel Pharma | Aminoacyllabdane, verfahren und zwischenprodukte zu ihrer herstellung und ihre verwendung als arzneimittel. |
| US4639443A (en) * | 1985-03-01 | 1987-01-27 | Hoechst-Roussel Pharmaceuticals Inc. | Labdane compounds, pharmaceutical compositions and use |
| DE3678736D1 (de) * | 1985-03-01 | 1991-05-23 | Hoechst Roussel Pharma | Labdanderivate, verfahren zu deren herstellung und deren verwendung als arzneimittel. |
| AU591196B2 (en) * | 1985-11-15 | 1989-11-30 | Nippon Kayaku Kabushiki Kaisha | Novel forskolin derivatives |
-
1985
- 1985-05-03 IN IN122/BOM/85A patent/IN163242B/en unknown
- 1985-10-02 DE DE19853535086 patent/DE3535086A1/de not_active Withdrawn
-
1986
- 1986-09-30 AU AU63270/86A patent/AU606036B2/en not_active Ceased
- 1986-09-30 IL IL80201A patent/IL80201A0/xx unknown
- 1986-10-01 EP EP86113486A patent/EP0217372B1/de not_active Expired - Lifetime
- 1986-10-01 HU HU864152A patent/HU203234B/hu not_active IP Right Cessation
- 1986-10-01 ES ES86113486T patent/ES2019863B3/es not_active Expired - Lifetime
- 1986-10-01 PT PT83478A patent/PT83478B/pt not_active IP Right Cessation
- 1986-10-01 DK DK468186A patent/DK468186A/da unknown
- 1986-10-01 DE DE8686113486T patent/DE3676922D1/de not_active Expired - Fee Related
- 1986-10-01 AT AT86113486T patent/ATE60054T1/de not_active IP Right Cessation
- 1986-10-01 JP JP61231365A patent/JPS6289677A/ja active Pending
- 1986-10-01 ZA ZA867495A patent/ZA867495B/xx unknown
- 1986-10-02 KR KR1019860008271A patent/KR870004051A/ko not_active Ceased
-
1988
- 1988-03-18 IN IN70/BOM/88A patent/IN164680B/en unknown
-
1991
- 1991-03-06 GR GR91400111T patent/GR3001559T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IN163242B (enrdf_load_stackoverflow) | 1988-08-27 |
| AU606036B2 (en) | 1991-01-31 |
| DK468186D0 (da) | 1986-10-01 |
| PT83478B (pt) | 1989-05-31 |
| GR3001559T3 (en) | 1992-11-23 |
| KR870004051A (ko) | 1987-05-07 |
| ES2019863B3 (es) | 1991-07-16 |
| EP0217372B1 (de) | 1991-01-16 |
| HU203234B (en) | 1991-06-28 |
| EP0217372A2 (de) | 1987-04-08 |
| ZA867495B (en) | 1987-05-27 |
| IN164680B (enrdf_load_stackoverflow) | 1989-05-06 |
| HUT46319A (en) | 1988-10-28 |
| AU6327086A (en) | 1987-04-09 |
| DE3535086A1 (de) | 1987-04-16 |
| PT83478A (de) | 1986-11-01 |
| JPS6289677A (ja) | 1987-04-24 |
| EP0217372A3 (en) | 1988-03-30 |
| DE3676922D1 (de) | 1991-02-21 |
| IL80201A0 (en) | 1986-12-31 |
| ATE60054T1 (de) | 1991-02-15 |
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