DK464787A - Cis-platinkomplekser, deres fremstilling og anvendelse samt forprodukter og mellemprodukter ved fremstillingen heraf - Google Patents

Cis-platinkomplekser, deres fremstilling og anvendelse samt forprodukter og mellemprodukter ved fremstillingen heraf

Info

Publication number
DK464787A
DK464787A DK464787A DK464787A DK464787A DK 464787 A DK464787 A DK 464787A DK 464787 A DK464787 A DK 464787A DK 464787 A DK464787 A DK 464787A DK 464787 A DK464787 A DK 464787A
Authority
DK
Denmark
Prior art keywords
group
hydrogen atom
formula
fashion
bonded
Prior art date
Application number
DK464787A
Other languages
English (en)
Other versions
DK168387B1 (da
DK464787D0 (da
Inventor
Cenek Kolar
Konard Dehmel
Hans Peter Kraemer
Original Assignee
Behringwerke Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Behringwerke Ag filed Critical Behringwerke Ag
Publication of DK464787D0 publication Critical patent/DK464787D0/da
Publication of DK464787A publication Critical patent/DK464787A/da
Application granted granted Critical
Publication of DK168387B1 publication Critical patent/DK168387B1/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H23/00Compounds containing boron, silicon, or a metal, e.g. chelates, vitamin B12
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C247/00Compounds containing azido groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0086Platinum compounds
    • C07F15/0093Platinum compounds without a metal-carbon linkage

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK464787A 1986-09-08 1987-09-07 Cis-Platinkomplekser, deres fremstilling og mellemprodukter til fremstilling heraf DK168387B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19863630497 DE3630497A1 (de) 1986-09-08 1986-09-08 Cis-platin-komplexe, verfahren zu ihrer herstellung und diese verbindungen enthaltende pharmazeutische mittel
DE3630497 1986-09-08

Publications (3)

Publication Number Publication Date
DK464787D0 DK464787D0 (da) 1987-09-07
DK464787A true DK464787A (da) 1988-03-09
DK168387B1 DK168387B1 (da) 1994-03-21

Family

ID=6309120

Family Applications (1)

Application Number Title Priority Date Filing Date
DK464787A DK168387B1 (da) 1986-09-08 1987-09-07 Cis-Platinkomplekser, deres fremstilling og mellemprodukter til fremstilling heraf

Country Status (15)

Country Link
US (1) US5091521A (da)
EP (1) EP0263956B1 (da)
JP (1) JPS6368546A (da)
AT (1) ATE68500T1 (da)
AU (1) AU611394B2 (da)
CA (1) CA1313655C (da)
DE (2) DE3630497A1 (da)
DK (1) DK168387B1 (da)
ES (1) ES2039220T3 (da)
FI (1) FI86304C (da)
GR (1) GR3003522T3 (da)
MX (1) MX8132A (da)
NO (1) NO174055C (da)
PT (1) PT85655B (da)
ZA (1) ZA876619B (da)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU593608B2 (en) * 1986-10-07 1990-02-15 Board Of Regents, The University Of Texas System Hydrophobic CIS-platinum complexes efficiently incorporated into liposomes
DE3887194T2 (de) * 1987-05-08 1994-07-28 Sankyo Co Antitumor-Platinkomplexe, deren Herstellung und deren therapeutische Verwendung.
US4956459A (en) * 1987-07-17 1990-09-11 Georgetown University Platinum compounds suitable for use as pharmaceuticals
IT1216687B (it) * 1988-04-01 1990-03-08 Boehringer Biochemia Srl Complessi di platino (ii), loro preparazione e impiego come antitumorali.
DE3834098A1 (de) * 1988-10-07 1990-04-19 Behringwerke Ag Cis-platin-komplexe mit einem 1,3-diaminopropan-derivat als liganden, verfahren zu ihrer herstellung und diese verbindung enthaltende pharmazeutische mittel
US5871710A (en) * 1992-09-04 1999-02-16 The General Hospital Corporation Graft co-polymer adducts of platinum (II) compounds
AU2701395A (en) * 1994-06-27 1996-01-19 General Hospital Corporation, The Graft co-polymer adducts of platinum (ii) compounds
US5760480A (en) * 1995-09-20 1998-06-02 Advanced Micro Devics, Inc. Low RC interconnection
US6235782B1 (en) 1998-11-12 2001-05-22 Rifat Pamukcu Method for treating a patient with neoplasia by treatment with a platinum coordination complex
US6235776B1 (en) 1998-11-12 2001-05-22 Cell Pathways, Inc. Method for treating a patient with neoplasia by treatment with a paclitaxel derivative
US7208611B2 (en) * 2005-02-23 2007-04-24 Xenoport, Inc. Platinum-containing compounds exhibiting cytostatic activity, synthesis and methods of use
AU2008331439B9 (en) * 2007-12-07 2014-04-10 Prana Biotechnology Ltd Compounds for therapy and diagnosis
CN109293927A (zh) 2009-02-04 2019-02-01 布里格姆及妇女医院股份有限公司 纳米级铂化合物及其使用方法
ES2588979T3 (es) 2010-08-24 2016-11-08 Dana-Farber Cancer Institute, Inc. Procedimientos para la predicción de una respuesta contra el cáncer
EP2721181B1 (en) 2011-06-17 2019-12-18 Myriad Genetics, Inc. Methods and materials for assessing allelic imbalance
EP2794907B2 (en) 2011-12-21 2022-11-23 Myriad Genetics, Inc. Methods and materials for assessing loss of heterozygosity
CA2864481C (en) 2012-02-23 2020-07-14 The Children's Hospital Corporation Methods for predicting anti-cancer response
EP2859118B1 (en) 2012-06-07 2017-11-22 Institut Curie Methods for detecting inactivation of the homologous recombination pathway (brca1/2) in human tumors
US10308986B2 (en) 2013-03-14 2019-06-04 Children's Medical Center Corporation Cancer diagnosis, treatment selection and treatment
US11149316B2 (en) 2013-12-09 2021-10-19 Institut Curie Methods for detecting inactivation of the homologous recombination pathway (BRCA1/2) in human tumors
ES2800673T3 (es) 2014-08-15 2021-01-04 Myriad Genetics Inc Métodos y materiales para evaluar una deficiencia de recombinación homóloga

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7807334A (nl) * 1978-07-06 1980-01-08 Tno Platina-diaminecomplexen, werkwijze voor het bereiden daarvan, werkwijze voor het bereiden van een genees- middel met toepassing van een dergelijk platina-dia- minecomplex voor de behandeling van kanker, alsmede al- dus verkregen gevormd geneesmiddel.
NL8204067A (nl) * 1982-10-21 1984-05-16 Tno Platina-diaminecomplexen, werkwijze voor het bereiden daarvan, werkwijze voor het bereiden van een geneesmiddel met toepassing van een dergelijk platinadiaminecomplex voor de behandeling van kanker, alsmede aldus verkregen gevormd geneesmiddel.
US4500465A (en) * 1982-06-28 1985-02-19 Engelhard Corporation Solubilized platinum (II) complexes
DE3503620A1 (de) * 1984-06-30 1986-01-23 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung von 1-azidoaldosen
DE3432320A1 (de) * 1984-09-03 1986-03-13 Behringwerke Ag, 3550 Marburg Cis-platin-komplexe mit einem pentaerythritderivat als liganden, verfahren zu ihrer herstellung und diese verbindungen enthaltendes pharmazeutisches mittel
JPS6259294A (ja) * 1985-09-09 1987-03-14 Ajinomoto Co Inc 白金錯体および抗腫瘍剤
US4760157A (en) * 1986-01-31 1988-07-26 American Cyanamid Company (2,2,-bis(aminomethyl)-1,3-propanediol-N,N')platinum complexes

Also Published As

Publication number Publication date
DK168387B1 (da) 1994-03-21
DK464787D0 (da) 1987-09-07
PT85655A (de) 1987-10-01
CA1313655C (en) 1993-02-16
EP0263956B1 (de) 1991-10-16
EP0263956A2 (de) 1988-04-20
JPS6368546A (ja) 1988-03-28
NO174055C (no) 1994-03-09
FI873841A (fi) 1988-03-09
GR3003522T3 (da) 1993-03-16
ATE68500T1 (de) 1991-11-15
FI86304B (fi) 1992-04-30
PT85655B (pt) 1990-05-31
EP0263956A3 (en) 1988-10-05
NO873721L (no) 1988-03-09
DE3773829D1 (de) 1991-11-21
AU611394B2 (en) 1991-06-13
DE3630497A1 (de) 1988-03-10
FI873841A0 (fi) 1987-09-04
ES2039220T3 (es) 1993-09-16
US5091521A (en) 1992-02-25
MX8132A (es) 1994-02-28
FI86304C (fi) 1992-08-10
ZA876619B (en) 1988-04-27
NO174055B (no) 1993-11-29
NO873721D0 (no) 1987-09-07
AU7810387A (en) 1988-03-10

Similar Documents

Publication Publication Date Title
DK464787A (da) Cis-platinkomplekser, deres fremstilling og anvendelse samt forprodukter og mellemprodukter ved fremstillingen heraf
PT72305B (de) Neue sulfonamide verfahren zu deren herstellung sowie diese verbindungen enthaltende arzneimittel
KR850002740A (ko) 페닐에탄올아민 유도체의 제조방법
ES546648A0 (es) Procedimiento para preparar complejos de cis-platino
DK570689A (da) Imidazolderivater
GB1419080A (en) Chemical compounds having juvenile hormone activity
JPS5543077A (en) Preparation of 1,3-dithiolan-2-ylidenemalonate derivative
GB1363267A (en) Phenoxyalkylamines process for their preparation and applications
ES8705362A1 (es) Un procedimiento para la preparacion de nuevas aminas terciarias
JPS5772970A (en) Azolylalkyl derivatives, manufacture and use as fungicide
ZA859706B (en) Organic compounds and their pharmaceutical use
KR890003692A (ko) 1.2.5.6- 테트라히드로피리딘-3-카르복스알데히드의 옥심유도체, 이들의 제조방법, 약제로서의 이들의 용도 및 이들을 함유하는 조성물
EP0281412A3 (en) Novel organic platinum complex pharmaceutical compositions containing same and a process for the preparation thereof
MY110450A (en) Imidazolylmethyl-pyridines, their production their use as pharmaceuticals and pharmaceutical compositions containing them
KR860007191A (ko) 폴리프레닐 화합물의 제조방법
IT8621999A1 (it) Derivati pirido-benzotiazinici ad attività antibatterica ed a lunga durata di azione
ES420718A1 (es) Procedimiento para la obtencion de dibenzazecinas.
ES488388A1 (es) Procedimiento de preparacion de derivados hidroxilados del tiazol
GB2022413B (en) Compositions containing cyclopentyl compounds
JPS56120669A (en) Allophanoylpiperazine compound and analgesic agent containing the same as active constituent
KR890005027A (ko) 페녹시알킬카복실산 유도체 및 그의 제조방법
JPS55129295A (en) Amidino derivative of insulin secretion stimulating substance
ES420717A1 (es) Procedimiento para la obtencion de dibenzazecinas.
ATE28185T1 (de) Azetylenderivate mit enzyminhibierender wirkung, deren herstellung und deren verwendung als arzneimittel.
ES482540A1 (es) Procedimiento para la preparacion de 2-fenilamino-imidazoli-na-(2) sustituidas.