DK457583A - Fremgangsmaade til fremstilling af dihydropyrazolo(3,4-b)pyridin-derivater - Google Patents

Fremgangsmaade til fremstilling af dihydropyrazolo(3,4-b)pyridin-derivater Download PDF

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Publication number
DK457583A
DK457583A DK457583A DK457583A DK457583A DK 457583 A DK457583 A DK 457583A DK 457583 A DK457583 A DK 457583A DK 457583 A DK457583 A DK 457583A DK 457583 A DK457583 A DK 457583A
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DK
Denmark
Prior art keywords
dihydropyrazolo
preparing
pyridine derivatives
pyridine
derivatives
Prior art date
Application number
DK457583A
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English (en)
Other versions
DK160278B (da
DK160278C (da
DK457583D0 (da
Inventor
Ikuo Adachi
Teruo Yamamori
Motohiko Ueda
Hatsuo Sato
Original Assignee
Shionogi & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi & Co filed Critical Shionogi & Co
Publication of DK457583D0 publication Critical patent/DK457583D0/da
Publication of DK457583A publication Critical patent/DK457583A/da
Publication of DK160278B publication Critical patent/DK160278B/da
Application granted granted Critical
Publication of DK160278C publication Critical patent/DK160278C/da

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/38Nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/49Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
    • C07C205/56Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups bound to carbon atoms of six-membered aromatic rings and carboxyl groups bound to acyclic carbon atoms of the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D407/00Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/04Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Obesity (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK457583A 1982-10-05 1983-10-04 Analogifremgangsmaade til fremstilling af dihydropyrazolo(3,4-b)-pyridinderivater DK160278C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP17676382 1982-10-05
JP57176763A JPS5965089A (ja) 1982-10-05 1982-10-05 ジヒドロピラゾロ〔3,4−b〕ピリジン誘導体およびその製造法

Publications (4)

Publication Number Publication Date
DK457583D0 DK457583D0 (da) 1983-10-04
DK457583A true DK457583A (da) 1984-04-06
DK160278B DK160278B (da) 1991-02-18
DK160278C DK160278C (da) 1991-07-22

Family

ID=16019382

Family Applications (1)

Application Number Title Priority Date Filing Date
DK457583A DK160278C (da) 1982-10-05 1983-10-04 Analogifremgangsmaade til fremstilling af dihydropyrazolo(3,4-b)-pyridinderivater

Country Status (8)

Country Link
EP (1) EP0107619B1 (da)
JP (1) JPS5965089A (da)
KR (1) KR900006448B1 (da)
AU (1) AU568092B2 (da)
DE (1) DE3372770D1 (da)
DK (1) DK160278C (da)
ES (1) ES8502993A1 (da)
GB (1) GB2128186B (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60197685A (ja) * 1984-03-19 1985-10-07 Shionogi & Co Ltd 4,7―ジヒドロピラゾロ[3,4―b]ピリジン誘導体とその製造法
US4873334A (en) * 1982-10-05 1989-10-10 Shionogi & Co., Ltd. 4,7-dihydropyrazolo(3,4-b) pyridine derivatives
GR79111B (da) * 1982-12-20 1984-10-02 Lepetit Spa
JPS6056979A (ja) * 1983-09-08 1985-04-02 Shionogi & Co Ltd 4,7−ジヒドロピラゾロ〔3,4−b〕ピリジン誘導体およびその製造法
JPS60246387A (ja) * 1984-05-22 1985-12-06 Yoshitomi Pharmaceut Ind Ltd ジヒドロイミダゾ〔1,2−a〕ピリミジン誘導体
US4918074A (en) * 1984-03-12 1990-04-17 Yoshitomi Pharmaceutical Industries, Ltd. Polyazaheterocycle compounds
JPS6210087A (ja) * 1985-07-03 1987-01-19 Shionogi & Co Ltd 4,7−ジヒドロチエノ〔2,3−b〕ピリジン誘導体,その製造法および循環器系疾患治療剤
EP0355234A1 (en) * 1988-08-25 1990-02-28 Merrell Dow Pharmaceuticals Inc. Pyrazolopyridine derivatives as antiatherosclerotic and antihypercholesterolemic agents
BR9713027A (pt) 1996-11-12 2000-01-25 Novartis Ag Derivados de pirazol úteis como herbicidas
US6977262B2 (en) 2001-02-02 2005-12-20 Mitsubishi Pharma Corporation Dihydropyrazolopyridine compounds and pharmaceutical use thereof
CN1630656A (zh) * 2001-02-02 2005-06-22 三菱制药株式会社 二氢吡唑并吡啶化合物及其制药用途
EP2508204B1 (en) 2002-06-26 2014-09-24 Ono Pharmaceutical Co., Ltd. Remedies for diseases caused by vascular contraction or dilation

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3857849A (en) * 1973-02-28 1974-12-31 Bayer Ag 2-amino-1,4-dihydropyridine derivatives
GR79111B (da) * 1982-12-20 1984-10-02 Lepetit Spa

Also Published As

Publication number Publication date
KR900006448B1 (ko) 1990-08-31
KR840006482A (ko) 1984-11-30
GB2128186A (en) 1984-04-26
DE3372770D1 (en) 1987-09-03
AU1990283A (en) 1984-04-12
AU568092B2 (en) 1987-12-17
GB2128186B (en) 1986-04-30
DK160278B (da) 1991-02-18
ES525668A0 (es) 1985-02-01
GB8325024D0 (en) 1983-10-19
EP0107619A1 (en) 1984-05-02
EP0107619B1 (en) 1987-07-29
JPH036151B2 (da) 1991-01-29
ES8502993A1 (es) 1985-02-01
JPS5965089A (ja) 1984-04-13
DK160278C (da) 1991-07-22
DK457583D0 (da) 1983-10-04

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