DK436784D0 - Beta-butyrolacton-derivater, fremgangsmaade til deres fremstilling samt immunomodulerende midler indeholdende disse derivater som aktive bestanddele - Google Patents

Beta-butyrolacton-derivater, fremgangsmaade til deres fremstilling samt immunomodulerende midler indeholdende disse derivater som aktive bestanddele

Info

Publication number
DK436784D0
DK436784D0 DK436784A DK436784A DK436784D0 DK 436784 D0 DK436784 D0 DK 436784D0 DK 436784 A DK436784 A DK 436784A DK 436784 A DK436784 A DK 436784A DK 436784 D0 DK436784 D0 DK 436784D0
Authority
DK
Denmark
Prior art keywords
derivatives
butyrolacton
beta
procedures
preparation
Prior art date
Application number
DK436784A
Other languages
English (en)
Other versions
DK436784A (da
Inventor
Tomei Oguri
Yasuhiro Morinaka
Shuichiro Kadowaki
Original Assignee
Mitsubishi Yuka Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsubishi Yuka Pharma filed Critical Mitsubishi Yuka Pharma
Publication of DK436784D0 publication Critical patent/DK436784D0/da
Publication of DK436784A publication Critical patent/DK436784A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/32—Oxygen atoms
    • C07D307/33—Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/58—One oxygen atom, e.g. butenolide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/94—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom spiro-condensed with carbocyclic rings or ring systems, e.g. griseofulvins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Furan Compounds (AREA)
DK436784A 1983-09-13 1984-09-12 Beta-butyrolacton-derivater, fremgangsmaade til deres fremstilling samt immunomodulerende midler indeholdende disse derivater som aktive bestanddele DK436784A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP58167521A JPS6058973A (ja) 1983-09-13 1983-09-13 γ−プチロラクトン誘導体及びそれを有効成分とする免疫調節剤

Publications (2)

Publication Number Publication Date
DK436784D0 true DK436784D0 (da) 1984-09-12
DK436784A DK436784A (da) 1985-03-14

Family

ID=15851231

Family Applications (1)

Application Number Title Priority Date Filing Date
DK436784A DK436784A (da) 1983-09-13 1984-09-12 Beta-butyrolacton-derivater, fremgangsmaade til deres fremstilling samt immunomodulerende midler indeholdende disse derivater som aktive bestanddele

Country Status (8)

Country Link
US (1) US4613613A (da)
EP (1) EP0139206B1 (da)
JP (1) JPS6058973A (da)
AT (1) ATE35812T1 (da)
AU (1) AU575342B2 (da)
CA (1) CA1269389A (da)
DE (1) DE3472791D1 (da)
DK (1) DK436784A (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3615157A1 (de) * 1986-05-05 1987-11-12 Schwabe Willmar Gmbh & Co 5-arylalkyl-4-alkoxy-2(5h)-furanone, zwischenprodukte und verfahren zu ihrer herstellung sowie ihre anwendung als therapeutische wirkstoffe
US4876359A (en) * 1986-10-07 1989-10-24 Ss Pharmaceutical Co., Ltd. Novel gamma-butyrolactone derivatives
US5043457A (en) * 1990-04-17 1991-08-27 Allergan, Inc. 2(5H)-furanones substituted in the 3 position, as Ca2+ channel antagonists and anti-inflammatory agents
DE69231892T2 (de) * 1991-01-10 2001-11-15 Santen Pharmaceutical Co Ltd Cyclische verbindung
JP2906236B2 (ja) * 1992-01-31 1999-06-14 参天製薬株式会社 ビシクロ化合物
AU2008202109B2 (en) * 2001-06-13 2012-02-02 Magnachem International Laboratories, Inc Lactone formulations and method of use
BR0210432A (pt) * 2001-06-13 2004-08-03 Magnachem Int Lab Inc Formulações de lactona e processo de uso
CN1720242A (zh) * 2002-11-05 2006-01-11 马格纳化学国际实验室公司 合成的内酯制剂及其使用方法
WO2005102315A1 (en) * 2004-04-23 2005-11-03 Magnachem International Laboratories, Inc. Synthetic lactone formulations for pain control
FR2898817B1 (fr) * 2006-03-23 2008-08-08 Univ Rouen Association de substance oleagineuse avec un melange d'au moins deux cyclodextrines
CA2741526A1 (en) * 2008-10-24 2010-04-29 Magnachem International Laboratories, Inc. Method for screening for compounds selectively interacting with rad9
CN113968833B (zh) * 2021-12-03 2023-02-28 西北农林科技大学 含α-亚甲基-γ-丁内酯结构的酚类衍生物、制备方法及其应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3328415A (en) * 1961-06-29 1967-06-27 Sterling Drug Inc 5-(2-hydroxyethyl)-4-thiazolidones and derivatives thereof
DE1218440B (de) * 1963-11-30 1966-06-08 Schering Ag Verfahren zur Herstellung alpha, beta-ungesaettigter gamma-Laktone
DE1920176A1 (de) * 1969-04-21 1970-10-22 Thomae Gmbh Dr K Neues Verfahren zur Herstellung von Hydroxycrotonsaeurelaktonen
CH647772A5 (fr) * 1979-05-07 1985-02-15 Delalande Sa Derives de la 5h-furanone-2 et de la 3h-dihydro-furanone-2, leurs procedes de preparation, et medicament les contenant.
EP0038600A1 (en) * 1980-04-21 1981-10-28 Akzo N.V. Bis-hydroxybenzyl derivatives, processes for their preparation and pharmaceutical composition containing same
JPS57183778A (en) * 1981-04-30 1982-11-12 Nippon Synthetic Chem Ind Co Ltd:The S-(3-phthalidyl)-l-cysteine and its preparation
JPS588044A (ja) * 1981-07-06 1983-01-18 Maruzen Seiyaku Kk １１−デオキソグリチルレチン酸水素マレ−ト及びそれを有効成分とする医薬
JPS5879989A (ja) * 1981-11-09 1983-05-13 Daicel Chem Ind Ltd ２（５ｈ）−フラノン誘導体
RO86439B (ro) * 1982-01-15 1985-03-31 Eli Lilly And Company Procedeu pentru prepararea unor derivati de acid ascorbic

Also Published As

Publication number Publication date
EP0139206B1 (en) 1988-07-20
DK436784A (da) 1985-03-14
AU575342B2 (en) 1988-07-28
EP0139206A1 (en) 1985-05-02
JPS6058973A (ja) 1985-04-05
US4613613A (en) 1986-09-23
CA1269389A (en) 1990-05-22
ATE35812T1 (de) 1988-08-15
DE3472791D1 (en) 1988-08-25
JPH0261950B2 (da) 1990-12-21
AU3286084A (en) 1985-03-21

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AHS Application shelved for other reasons than non-payment