DK4151277T3 - Substitueret piperidinforbindelse og anvendelse deraf - Google Patents

Substitueret piperidinforbindelse og anvendelse deraf

Info

Publication number
DK4151277T3
DK4151277T3 DK21842047.9T DK21842047T DK4151277T3 DK 4151277 T3 DK4151277 T3 DK 4151277T3 DK 21842047 T DK21842047 T DK 21842047T DK 4151277 T3 DK4151277 T3 DK 4151277T3
Authority
DK
Denmark
Prior art keywords
piperidine compound
substituted piperidine
substituted
compound
piperidine
Prior art date
Application number
DK21842047.9T
Other languages
Danish (da)
English (en)
Inventor
Yu Yoshida
Yoichi Kita
Makoto Kotake
Keiichi Sorimachi
Toshiyuki OHFUSA
Takafumi Motoki
Taro ASABA
Original Assignee
Eisai R&D Man Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai R&D Man Co Ltd filed Critical Eisai R&D Man Co Ltd
Application granted granted Critical
Publication of DK4151277T3 publication Critical patent/DK4151277T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08Bridged systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D451/00Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pain & Pain Management (AREA)
DK21842047.9T 2020-07-17 2021-07-15 Substitueret piperidinforbindelse og anvendelse deraf DK4151277T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2020122864 2020-07-17
PCT/JP2021/026649 WO2022014680A1 (ja) 2020-07-17 2021-07-15 置換ピペリジン化合物及びその用途

Publications (1)

Publication Number Publication Date
DK4151277T3 true DK4151277T3 (da) 2026-04-13

Family

ID=79291962

Family Applications (1)

Application Number Title Priority Date Filing Date
DK21842047.9T DK4151277T3 (da) 2020-07-17 2021-07-15 Substitueret piperidinforbindelse og anvendelse deraf

Country Status (23)

Country Link
US (1) US11479552B2 (https=)
EP (1) EP4151277B1 (https=)
JP (1) JP7190612B2 (https=)
KR (1) KR20230040953A (https=)
CN (3) CN119235864A (https=)
AR (1) AR122973A1 (https=)
AU (1) AU2021308053A1 (https=)
BR (1) BR112022026161A2 (https=)
CA (1) CA3187835A1 (https=)
CL (1) CL2022003666A1 (https=)
CO (1) CO2022018446A2 (https=)
DK (1) DK4151277T3 (https=)
FI (1) FI4151277T3 (https=)
IL (1) IL299125B2 (https=)
JO (1) JOP20220345A1 (https=)
LT (1) LT4151277T (https=)
MX (1) MX2022016388A (https=)
PE (1) PE20231103A1 (https=)
PH (1) PH12022553488A1 (https=)
TW (1) TWI888599B (https=)
UA (1) UA129636C2 (https=)
WO (1) WO2022014680A1 (https=)
ZA (1) ZA202213562B (https=)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4065585B1 (en) 2019-11-25 2025-08-20 Alkermes, Inc. Substituted macrocyclic compounds and related methods of treatment
US11760747B2 (en) 2020-12-21 2023-09-19 Alkermes, Inc. Substituted piperidino compounds and related methods of treatment
US12006330B2 (en) 2020-12-21 2024-06-11 Alkermes, Inc. Substituted macrocyclic compounds and related methods of treatment
JP7591592B2 (ja) * 2022-01-14 2024-11-28 エーザイ・アール・アンド・ディー・マネジメント株式会社 置換ピペリジン化合物を含有する医薬
JPWO2023136279A1 (https=) * 2022-01-14 2023-07-20
WO2024075825A1 (ja) * 2022-10-07 2024-04-11 キッセイ薬品工業株式会社 シクロペンタン化合物
EP4611745A1 (en) * 2022-10-31 2025-09-10 Takeda Pharmaceutical Company Limited Dosing of orexin type 2 receptor agonists
WO2024128305A1 (ja) 2022-12-16 2024-06-20 第一三共株式会社 2-アザビシクロ[3.1.1]ヘプタン化合物
EP4719397A1 (en) 2023-06-02 2026-04-08 Takeda Pharmaceutical Company Limited Use of an orexin 2 receptor agonist for improving respiratory function during sleep
WO2025124698A1 (en) 2023-12-12 2025-06-19 Idorsia Pharmaceuticals Ltd Aryl sulfone and sulfanone derivatives as orexin receptor modulators
TW202542165A (zh) 2023-12-19 2025-11-01 瑞士商愛杜西亞製藥有限公司 大環食慾素激動劑
WO2025137359A1 (en) 2023-12-20 2025-06-26 Eisai R&D Management Co., Ltd. Assay methods to identify a disease
WO2025229493A1 (en) 2024-04-29 2025-11-06 Takeda Pharmaceutical Company Limited Dosing of orexin type 2 receptor agonists

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG34208A1 (en) 1995-03-01 1996-12-06 Guy Andrew Vaz Blast and fragment resistant polyurethane boot sole for safety footwear
EP0828751A4 (en) 1995-05-05 1999-01-20 Human Genome Sciences Inc HUMAN NEUROPEPTIDE RECEPTOR
US6309854B1 (en) 1996-12-17 2001-10-30 Smithkline Beecham Corporation Polynucleotides encoding ligands of the neuropeptide receptor HFGAN72
US6159605A (en) 1997-02-18 2000-12-12 Dainichiseika Color & Chemicals Mfg. Co., Ltd. Ink-jet recording sheet
US5935814A (en) 1997-04-30 1999-08-10 Smithkline Beecham Corporation Polynucleotides encoding HFGAN72Y receptor
US6020157A (en) 1997-04-30 2000-02-01 Smithkline Beecham Corporation Polynucleotides encoding HFGAN72X receptor
US6166193A (en) 1997-07-25 2000-12-26 Board Of Regents, University Of Texas System Polynucleotides encoding MY1 receptor
KR100327888B1 (ko) 1999-07-14 2002-03-09 정숭렬 도로포장 파손촉진 시험장치의 무선제어 시스템
AU2004274309B2 (en) * 2003-09-22 2010-04-08 Msd K.K. Novel piperidine derivative
EP1805183B1 (en) 2004-10-20 2010-12-29 NeuroSearch A/S Novel diazabicyclic aryl derivatives and their medical use
JP2009184924A (ja) 2006-05-31 2009-08-20 Eisai R & D Management Co Ltd 生物学的試薬用化合物
TW201444849A (zh) 2013-03-13 2014-12-01 Janssen Pharmaceutica Nv 經取代的7-氮雜雙環類及其作為食慾激素受體調節劑之用途

Also Published As

Publication number Publication date
IL299125B1 (en) 2025-11-01
CL2022003666A1 (es) 2023-05-26
CA3187835A1 (en) 2022-01-20
CN115884971B (zh) 2024-11-05
US20220017517A1 (en) 2022-01-20
ZA202213562B (en) 2023-10-25
AU2021308053A1 (en) 2023-02-02
IL299125A (en) 2023-02-01
JOP20220345A1 (ar) 2022-12-21
TW202542144A (zh) 2025-11-01
EP4151277A1 (en) 2023-03-22
TWI888599B (zh) 2025-07-01
EP4151277B1 (en) 2026-01-28
JPWO2022014680A1 (https=) 2022-01-20
MX2022016388A (es) 2023-01-30
TW202216705A (zh) 2022-05-01
JP7190612B2 (ja) 2022-12-15
US11479552B2 (en) 2022-10-25
IL299125B2 (en) 2026-03-01
FI4151277T3 (fi) 2026-03-27
CN119258067A (zh) 2025-01-07
WO2022014680A1 (ja) 2022-01-20
CN115884971A (zh) 2023-03-31
UA129636C2 (uk) 2025-06-18
PE20231103A1 (es) 2023-07-19
CN119235864A (zh) 2025-01-03
AR122973A1 (es) 2022-10-19
EP4151277A4 (en) 2024-06-26
BR112022026161A2 (pt) 2023-01-31
KR20230040953A (ko) 2023-03-23
CO2022018446A2 (es) 2023-03-07
LT4151277T (lt) 2026-04-10
PH12022553488A1 (en) 2024-04-22

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