DK408083A - Isoquinolinderivater, deres fremstilling og anvendelse - Google Patents
Isoquinolinderivater, deres fremstilling og anvendelse Download PDFInfo
- Publication number
- DK408083A DK408083A DK408083A DK408083A DK408083A DK 408083 A DK408083 A DK 408083A DK 408083 A DK408083 A DK 408083A DK 408083 A DK408083 A DK 408083A DK 408083 A DK408083 A DK 408083A
- Authority
- DK
- Denmark
- Prior art keywords
- preparation
- isoquinoline derivatives
- isoquinoline
- meansings
- compounds
- Prior art date
Links
- AWJUIBRHMBBTKR-UHFFFAOYSA-N isoquinoline Chemical class C1=NC=CC2=CC=CC=C21 AWJUIBRHMBBTKR-UHFFFAOYSA-N 0.000 title 1
- 239000002253 acid Substances 0.000 abstract 1
- 230000003288 anthiarrhythmic effect Effects 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- MCVMLYSLPCECGO-UHFFFAOYSA-N isoquinoline-4-carboxylic acid Chemical class C1=CC=C2C(C(=O)O)=CN=CC2=C1 MCVMLYSLPCECGO-UHFFFAOYSA-N 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Heart & Thoracic Surgery (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19823233424 DE3233424A1 (de) | 1982-09-09 | 1982-09-09 | Isochinolinderivate, verfahren zu ihrer herstellung, pharmazeutische praeparate auf basis dieser verbindungen und ihre verwendung |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK408083D0 DK408083D0 (da) | 1983-09-08 |
| DK408083A true DK408083A (da) | 1984-03-10 |
Family
ID=6172780
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK408083A DK408083A (da) | 1982-09-09 | 1983-09-08 | Isoquinolinderivater, deres fremstilling og anvendelse |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US4673682A (enExample) |
| EP (1) | EP0105210B1 (enExample) |
| JP (1) | JPS5967270A (enExample) |
| KR (1) | KR840006206A (enExample) |
| AT (1) | ATE25679T1 (enExample) |
| AU (1) | AU1891683A (enExample) |
| CA (1) | CA1211445A (enExample) |
| DE (2) | DE3233424A1 (enExample) |
| DK (1) | DK408083A (enExample) |
| ES (1) | ES525441A0 (enExample) |
| FI (1) | FI833200A7 (enExample) |
| GR (1) | GR79382B (enExample) |
| HU (1) | HU191094B (enExample) |
| IL (1) | IL69683A0 (enExample) |
| NO (1) | NO833217L (enExample) |
| NZ (1) | NZ205513A (enExample) |
| PH (1) | PH18186A (enExample) |
| PT (1) | PT77309B (enExample) |
| ZA (1) | ZA836663B (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4956371A (en) * | 1989-09-19 | 1990-09-11 | Euroceltique, S.A. | Substituted isoquinolines and methods of using same |
| EP0590455B1 (en) * | 1992-09-28 | 2000-12-27 | Hoechst Aktiengesellschaft | Antiarrhythmic and cardioprotective substituted 1(2H)-isoquinolines, process for their production, medicament containing them and their use for the production of a medicament for combating heart failures |
| US5552412A (en) * | 1995-01-09 | 1996-09-03 | Pfizer Inc | 5-substitued-6-cyclic-5,6,7,8-tetrahydronaphthalen2-ol compounds which are useful for treating osteoporosis |
| DE602004031114D1 (de) * | 2003-06-06 | 2011-03-03 | Fibrogen Inc | Stickstoffhaltige heteroarylverbindungen und deren verwendungen zur erhoehung des gehaltes von endogenem erythropoietin |
| ZA200806752B (en) | 2006-01-27 | 2009-10-28 | Fibrogen Inc | Cyanoisoquinoline compounds that stabilize hypoxia inducible factor (HIF) |
| KR101084635B1 (ko) * | 2006-04-04 | 2011-11-18 | 피브로겐, 인크. | Ｈｉｆ 조절제로서 피롤로- 및 티아졸로-피리딘 화합물 |
| NZ592741A (en) | 2008-11-14 | 2013-03-28 | Fibrogen Inc | Thiochromene derivatives as hif hydroxylase inhibitors |
| NZ700760A (en) | 2012-03-09 | 2016-08-26 | Fibrogen Inc | 4 -hydroxy- isoquinoline compounds as hif hydroxylase inhibitors |
| JP6196671B2 (ja) | 2012-07-16 | 2017-09-13 | フィブロジェン インコーポレイテッド | イソキノリン化合物を作製する方法 |
| KR102318720B1 (ko) | 2012-07-16 | 2021-10-28 | 피브로겐, 인크. | 프롤릴 하이드록실라제 억제제 [(4-하이드록시-1-메틸-7-페녹시-아이소퀴놀린-3-카보닐)-아미노]-아세트산의 결정형 |
| US8883823B2 (en) | 2012-07-16 | 2014-11-11 | Fibrogen, Inc. | Crystalline forms of a prolyl hydroxylase inhibitor |
| DK2951159T3 (en) | 2013-01-24 | 2018-11-19 | Fibrogen Inc | CRYSTALLIC FORMS OF {[1-CYANO-5- (4-CHLORPHENOXY) -4-HYDROXY-ISOQUINOLIN-3-CARBONYL] -AMINO} ACETIC ACID |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2054482B1 (enExample) * | 1969-07-11 | 1973-06-08 | Anvar | |
| FR2424270A1 (fr) * | 1978-04-24 | 1979-11-23 | Rhone Poulenc Ind | Nouveaux derives de l'isoquinoleine, leur preparation et les compositions qui les contiennent |
| DE2818423A1 (de) * | 1978-04-27 | 1979-11-08 | Hoechst Ag | Neue isochinolinderivate und verfahren zu ihrer herstellung |
-
1982
- 1982-09-09 DE DE19823233424 patent/DE3233424A1/de not_active Withdrawn
-
1983
- 1983-09-03 AT AT83108697T patent/ATE25679T1/de not_active IP Right Cessation
- 1983-09-03 EP EP83108697A patent/EP0105210B1/de not_active Expired
- 1983-09-03 DE DE8383108697T patent/DE3369983D1/de not_active Expired
- 1983-09-07 PH PH29505A patent/PH18186A/en unknown
- 1983-09-07 US US06/530,000 patent/US4673682A/en not_active Expired - Fee Related
- 1983-09-07 ES ES525441A patent/ES525441A0/es active Granted
- 1983-09-07 IL IL69683A patent/IL69683A0/xx unknown
- 1983-09-07 KR KR1019830004199A patent/KR840006206A/ko not_active Withdrawn
- 1983-09-07 FI FI833200A patent/FI833200A7/fi not_active Application Discontinuation
- 1983-09-07 GR GR72399A patent/GR79382B/el unknown
- 1983-09-07 NZ NZ205513A patent/NZ205513A/en unknown
- 1983-09-08 JP JP58164274A patent/JPS5967270A/ja active Pending
- 1983-09-08 HU HU833134A patent/HU191094B/hu unknown
- 1983-09-08 ZA ZA836663A patent/ZA836663B/xx unknown
- 1983-09-08 NO NO833217A patent/NO833217L/no unknown
- 1983-09-08 DK DK408083A patent/DK408083A/da not_active Application Discontinuation
- 1983-09-08 PT PT77309A patent/PT77309B/pt unknown
- 1983-09-08 AU AU18916/83A patent/AU1891683A/en not_active Abandoned
- 1983-09-08 CA CA000436316A patent/CA1211445A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| NO833217L (no) | 1984-03-12 |
| PT77309A (de) | 1983-10-01 |
| JPS5967270A (ja) | 1984-04-16 |
| EP0105210A3 (en) | 1984-10-10 |
| FI833200A7 (fi) | 1984-03-10 |
| GR79382B (enExample) | 1984-10-22 |
| ES8404852A1 (es) | 1984-05-16 |
| ZA836663B (en) | 1984-04-25 |
| IL69683A0 (en) | 1983-12-30 |
| PH18186A (en) | 1985-04-12 |
| CA1211445A (en) | 1986-09-16 |
| PT77309B (de) | 1986-04-18 |
| NZ205513A (en) | 1986-05-09 |
| US4673682A (en) | 1987-06-16 |
| FI833200A0 (fi) | 1983-09-07 |
| DE3233424A1 (de) | 1984-03-15 |
| AU1891683A (en) | 1984-03-15 |
| KR840006206A (ko) | 1984-11-22 |
| DE3369983D1 (en) | 1987-04-09 |
| EP0105210A2 (de) | 1984-04-11 |
| ATE25679T1 (de) | 1987-03-15 |
| DK408083D0 (da) | 1983-09-08 |
| HU191094B (en) | 1987-01-28 |
| ES525441A0 (es) | 1984-05-16 |
| EP0105210B1 (de) | 1987-03-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ATS | Application withdrawn |