DK3985018T3 - Gbd-sstad-sstad rekombinant protein og fremgangsmåde til fremstilling og anvendelse af samme - Google Patents

Gbd-sstad-sstad rekombinant protein og fremgangsmåde til fremstilling og anvendelse af samme Download PDF

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Publication number
DK3985018T3
DK3985018T3 DK20905847.8T DK20905847T DK3985018T3 DK 3985018 T3 DK3985018 T3 DK 3985018T3 DK 20905847 T DK20905847 T DK 20905847T DK 3985018 T3 DK3985018 T3 DK 3985018T3
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Denmark
Prior art keywords
sstad
gbd
procedure
production
same
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DK20905847.8T
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English (en)
Inventor
Vyacheslav Viktorovich Rechetnik
Vali-Magomed Kadievich Magataev
Vladimir Glebovich Lunin
Sergei Mihailovich Yudin
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Urspharm
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Publication of DK3985018T3 publication Critical patent/DK3985018T3/da

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/655Somatostatins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70Vectors or expression systems specially adapted for E. coli
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64Cyclic peptides containing only normal peptide links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Public Health (AREA)
  • Toxicology (AREA)
  • Endocrinology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DK20905847.8T 2019-12-25 2020-12-02 Gbd-sstad-sstad rekombinant protein og fremgangsmåde til fremstilling og anvendelse af samme DK3985018T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
RU2019143669A RU2722849C1 (ru) 2019-12-25 2019-12-25 Рекомбинантный белок GBD-SSTad-SSTad, способ его получения и применения
PCT/EA2020/000003 WO2021129915A1 (ru) 2019-12-25 2020-12-02 Рекомбинантный белок gbd-sstad-sstad, способ его получения и применения

Publications (1)

Publication Number Publication Date
DK3985018T3 true DK3985018T3 (da) 2024-02-19

Family

ID=71067688

Family Applications (1)

Application Number Title Priority Date Filing Date
DK20905847.8T DK3985018T3 (da) 2019-12-25 2020-12-02 Gbd-sstad-sstad rekombinant protein og fremgangsmåde til fremstilling og anvendelse af samme

Country Status (6)

Country Link
US (1) US20220235112A1 (da)
EP (1) EP3985018B1 (da)
CN (1) CN114981296A (da)
DK (1) DK3985018T3 (da)
RU (1) RU2722849C1 (da)
WO (1) WO2021129915A1 (da)

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4162248A (en) * 1976-10-14 1979-07-24 Merck & Co., Inc. Somatostatin analogs
JPS5819669B2 (ja) 1978-10-28 1983-04-19 白井松新薬株式会社 新規生理活性ペプチド化合物及びその製造法
RU2031121C1 (ru) 1993-06-22 1995-03-20 Товарищество с ограниченной ответственностью "Ветек" СПОСОБ ПОЛУЧЕНИЯ РЕКОМБИНАНТНЫХ ПЛАЗМИДНЫХ pC(Sp)n , КОДИРУЮЩИХ ХИМЕРНЫЙ БЕЛОК С ПОСЛЕДОВАТЕЛЬНОСТЬЮ СОМАТОСТАТИНА-14;РЕКОМБИНАНТНАЯ ПЛАЗМИДНАЯ ДНК pC(Sp)4 , КОДИРУЮЩАЯ ЧАСТЬ ГЕНА ХЛОРАМФЕНИКОЛАЦЕТИЛТРАНСФЕРАЗЫ, ТЕТРАМЕРНЫЙ СПЕЙСЕР И СОМАТОСТАТИН-14;ШТАММ БАКТЕРИЙ ESCHERICHIA COLI - ПРОДУЦЕНТ ХИМЕРНОГО БЕЛКА С ПОСЛЕДОВАТЕЛЬНОСТЬЮ СОМАТОСТАТИНА-14;ПОЛИПЕПТИД
US6316004B1 (en) 1993-06-22 2001-11-13 T. Tikhonenko Chimeric somatostatin containing protein and encoding DNA, plasmids of expression, method for preparing chimeric protein, strain-producers, immunogenic composition, method for increasing the productivity of farm animals
WO2005021595A1 (en) * 2003-08-28 2005-03-10 Euro-Celtique S.A. Methods of antibody engineering using antibody display rules
EP1522311A1 (fr) 2003-10-10 2005-04-13 Institut National De La Sante Et De La Recherche Medicale (Inserm) Utilisation de la somatostine ou d'un de ses analogues pour préparer un médicament destiné à réguler la réserve folliculaire ovarienne chez la femme non ménopausée
RU2337708C1 (ru) 2007-02-22 2008-11-10 Сергей Михайлович Юдин Способ повышения мясной продуктивности бройлеров и препарат для его осуществления
WO2009158395A1 (en) 2008-06-25 2009-12-30 Braasch Biotech Llc Compositions and methods for enhanced somatostatin immunogenicity
RU2401304C2 (ru) * 2008-11-26 2010-10-10 Государственное учреждение Научно-исследовательский институт эпидемиологии и микробиологии имени почетного академика Н.Ф. Гамалеи Российской академии медицинских наук РЕКОМБИНАНТНАЯ ПЛАЗМИДА pD5spGBD, ШТАММ Escherichia coli - ПРОДУЦЕНТ РЕКОМБИНАНТНОГО БЕЛКА D5-GBD, РЕКОМБИНАНТНЫЙ БЕЛОК D5-GBD И СПОСОБ ЕГО ПОЛУЧЕНИЯ, СПОСОБ ИССЛЕДОВАНИЯ СВЯЗЫВАНИЯ БЕЛКА D5-GBD С АНТИТЕЛАМИ СЫВОРОТОК БОЛЬНЫХ, СПОСОБ ПОЛУЧЕНИЯ СПЕЦИФИЧЕСКИХ АНТИТЕЛ К БЕЛКУ D5-GBD
WO2011151782A1 (en) * 2010-06-02 2011-12-08 Preglem Sa A role for somatostatin to modulate initiation of follicular growth in the human ovary
RU2493873C1 (ru) 2012-06-07 2013-09-27 Сергей Михайлович Юдин Инъекционный препарат для повышения спермопродукции у производителей сельскохозяйственных животных и петухов и способ его применения
CN103103196A (zh) * 2013-02-04 2013-05-15 华中农业大学 一种修饰的山羊防御素基因及制备方法和应用
RU2526571C1 (ru) 2013-04-08 2014-08-27 Сергей Михайлович Юдин Инъекционный препарат для повышения спермопродукции человека и способ его применения
EP2835136A1 (en) 2013-08-07 2015-02-11 PregLem S.A. Somatostatin Receptor Modulator for the treatment of infertility
RU2561467C1 (ru) 2014-04-24 2015-08-27 Сергей Михайлович Юдин Способ получения препарата для повышения мясной и молочной продуктивности сельскохозяйственных животных (варианты) и препарат, полученный на его основе
RU2629871C1 (ru) * 2016-03-22 2017-09-04 Сергей Михайлович Юдин Препарат для стимуляции фолликулогенеза и способ его применения
RU2614115C1 (ru) * 2016-08-01 2017-03-22 Сергей Михайлович Юдин Рекомбинантный соматостатинсодержащий белок, способ его получения, инъекционный препарат для повышения мясной и молочной продуктивности сельскохозяйственных животных, а также способ использования препарата
CN106957363A (zh) * 2017-03-29 2017-07-18 广东工业大学 一种生长抑素14肽卵黄抗体及其制备方法
CN109422809A (zh) * 2017-08-24 2019-03-05 孙立春 全人源或人源化生长抑素受体ii单克隆抗体及其药物或诊断试剂的开发与应用

Also Published As

Publication number Publication date
RU2722849C1 (ru) 2020-06-04
US20220235112A1 (en) 2022-07-28
EP3985018A1 (en) 2022-04-20
EP3985018A4 (en) 2023-01-18
CN114981296A (zh) 2022-08-30
EP3985018B1 (en) 2024-01-10
WO2021129915A1 (ru) 2021-07-01

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