DK3737399T3 - Atf5-peptidvarianter og anvendelser deraf - Google Patents

Atf5-peptidvarianter og anvendelser deraf Download PDF

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Publication number
DK3737399T3
DK3737399T3 DK19735723.9T DK19735723T DK3737399T3 DK 3737399 T3 DK3737399 T3 DK 3737399T3 DK 19735723 T DK19735723 T DK 19735723T DK 3737399 T3 DK3737399 T3 DK 3737399T3
Authority
DK
Denmark
Prior art keywords
peptide variants
atf5 peptide
atf5
variants
peptide
Prior art date
Application number
DK19735723.9T
Other languages
English (en)
Inventor
Barry Jay Kappel
Gene Merutka
Jimmy Andrew Rotolo
Original Assignee
Sapience Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sapience Therapeutics Inc filed Critical Sapience Therapeutics Inc
Application granted granted Critical
Publication of DK3737399T3 publication Critical patent/DK3737399T3/da

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4705—Regulators; Modulating activity stimulating, promoting or activating activity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/73—Fusion polypeptide containing domain for protein-protein interaction containing coiled-coiled motif (leucine zippers)
DK19735723.9T 2018-01-03 2019-01-03 Atf5-peptidvarianter og anvendelser deraf DK3737399T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862613083P 2018-01-03 2018-01-03
PCT/US2019/012148 WO2019136125A1 (en) 2018-01-03 2019-01-03 Atf5 peptide variants and uses thereof

Publications (1)

Publication Number Publication Date
DK3737399T3 true DK3737399T3 (da) 2023-10-16

Family

ID=67059159

Family Applications (1)

Application Number Title Priority Date Filing Date
DK19735723.9T DK3737399T3 (da) 2018-01-03 2019-01-03 Atf5-peptidvarianter og anvendelser deraf

Country Status (16)

Country Link
US (2) US10525100B2 (da)
EP (2) EP4275757A3 (da)
JP (2) JP6971508B2 (da)
KR (2) KR102433761B1 (da)
CN (2) CN113845581A (da)
AU (2) AU2019205351B2 (da)
BR (1) BR112020013524A2 (da)
CA (2) CA3203983A1 (da)
DK (1) DK3737399T3 (da)
ES (1) ES2960784T3 (da)
FI (1) FI3737399T3 (da)
IL (3) IL290414B1 (da)
MX (1) MX2020006971A (da)
NZ (2) NZ765759A (da)
PT (1) PT3737399T (da)
WO (1) WO2019136125A1 (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ765759A (en) * 2018-01-03 2023-07-28 Sapience Therapeutics Inc Atf5 peptide variants and uses thereof
CA3180559A1 (en) * 2020-06-21 2021-12-30 Barry Jay Kappel Administration of cebp-beta antagonist and methods of use
CN113845574A (zh) * 2021-11-30 2021-12-28 百益美恒(北京)科技有限公司 一种穿透肽tdp、融合穿透肽蛋白及其制备方法和应用
US20240002806A1 (en) 2022-03-10 2024-01-04 Innocent Meat GmbH Method for differentiating adult stem cells into final tissue
WO2024053630A1 (ja) * 2022-09-07 2024-03-14 東亞合成株式会社 キャリアペプチドフラグメント及びその利用
WO2024084932A1 (ja) * 2022-10-17 2024-04-25 東亞合成株式会社 キャリアペプチドフラグメント及びその利用

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ATE258188T1 (de) 1992-08-27 2004-02-15 Deakin Res Ltd Retro-, inverso-, und retro-inverso synthetische peptidanaloge
JPH11510389A (ja) 1995-07-31 1999-09-14 アメリカ合衆国 細胞タンパク質の機能を不活性化するためのタンパク質−タンパク質相互作用表面の拡張
US20020160002A1 (en) 1996-06-18 2002-10-31 Irwin Gelman Tumor suppressor gene
US5955593A (en) 1996-09-09 1999-09-21 Washington University BH3 interacting domain death agonist
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US6551795B1 (en) * 1998-02-18 2003-04-22 Genome Therapeutics Corporation Nucleic acid and amino acid sequences relating to pseudomonas aeruginosa for diagnostics and therapeutics
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AU6857600A (en) * 1999-08-31 2001-03-26 Glaxo Group Limited Screen
AU7577600A (en) 1999-09-13 2001-04-17 Cornell Research Foundation Inc. Delivering to eucaryotic cells bacterial proteins that are secreted via type iiisecretion systems
US8183339B1 (en) 1999-10-12 2012-05-22 Xigen S.A. Cell-permeable peptide inhibitors of the JNK signal transduction pathway
US6468754B1 (en) 2000-04-18 2002-10-22 Iconix Pharmaceuticals, Inc. Vector and method for targeted replacement and disruption of an integrated DNA sequence
US20050164384A1 (en) 2003-04-04 2005-07-28 Greene Lloyd A. Methods for regulating differentiation of neural cells and uses thereof
US8158420B2 (en) * 2003-04-04 2012-04-17 The Trustees Of Columbia University In The City Of New York Methods for inhibiting the differentation of proliferative telencephalic cells in vitro by addition of ATF5
US7611893B2 (en) * 2005-11-09 2009-11-03 Ontherix, Inc. Metal-binding therapeutic peptides
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WO2008151037A1 (en) 2007-05-30 2008-12-11 Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services Peptide-based stat inhibitor
WO2010120931A2 (en) 2009-04-14 2010-10-21 University Of Medicine And Dentistry Of New Jersey E2f as a target for treatment of hormone refractory prostate cancer
CN103370080A (zh) 2010-02-04 2013-10-23 吉联亚生物科技有限公司 结合赖氨酰氧化酶样2（loxl2）的抗体和其使用方法
US8957026B2 (en) 2010-09-22 2015-02-17 President And Fellows Of Harvard College Beta-catenin targeting peptides and uses thereof
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CN103945850A (zh) * 2011-11-15 2014-07-23 诺华股份有限公司 磷酸肌醇-3-激酶抑制剂与Janus激酶2-信号转导和转录激活因子5通路的调节剂的组合
WO2014130758A1 (en) * 2013-02-22 2014-08-28 The Trustees Of Columbia Unversity In The City Of New York Compositions and methods for inhibiting tumor cells by inhibiting the transcription factor atf5
KR102092345B1 (ko) * 2013-09-30 2020-03-24 삼성전자주식회사 류신 지퍼 변이체 및 이의 용도
KR102272213B1 (ko) 2014-07-08 2021-07-01 삼성전자주식회사 표적화 부위, 절단 부위, 및 세포막 투과 부위를 포함하는 융합 단백질 및 그의 용도
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NZ765759A (en) * 2018-01-03 2023-07-28 Sapience Therapeutics Inc Atf5 peptide variants and uses thereof

Also Published As

Publication number Publication date
NZ765759A (en) 2023-07-28
AU2019205351B2 (en) 2020-10-08
EP3737399A4 (en) 2021-10-06
IL275774A (en) 2020-08-31
PT3737399T (pt) 2023-09-04
AU2019205351A1 (en) 2020-07-16
KR20220116583A (ko) 2022-08-23
WO2019136125A1 (en) 2019-07-11
IL281316B (en) 2022-06-01
IL290414B1 (en) 2024-04-01
KR102433761B1 (ko) 2022-08-22
CA3086768A1 (en) 2019-07-11
ES2960784T3 (es) 2024-03-06
IL275774B (en) 2021-03-25
EP4275757A3 (en) 2024-01-17
FI3737399T3 (fi) 2023-08-09
US11878047B2 (en) 2024-01-23
US10525100B2 (en) 2020-01-07
BR112020013524A2 (pt) 2020-12-08
MX2020006971A (es) 2020-09-09
JP6971508B2 (ja) 2021-11-24
KR20200086374A (ko) 2020-07-16
EP3737399B1 (en) 2023-07-26
IL290414A (en) 2022-04-01
CN111655277A (zh) 2020-09-11
CA3086768C (en) 2023-09-26
IL281316A (en) 2021-04-29
NZ801728A (en) 2024-03-22
EP3737399A1 (en) 2020-11-18
JP2022031646A (ja) 2022-02-22
CN111655277B (zh) 2021-10-12
EP4275757A2 (en) 2023-11-15
JP2021508503A (ja) 2021-03-11
AU2020256311A1 (en) 2020-11-12
US20210061869A1 (en) 2021-03-04
AU2020256311B2 (en) 2022-04-21
JP7312948B2 (ja) 2023-07-24
CN113845581A (zh) 2021-12-28
KR102606176B1 (ko) 2023-11-27
US20190201483A1 (en) 2019-07-04
CA3203983A1 (en) 2019-07-11

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