DK396886A - Gem-dihalogen-1,8-diamino-4-azaoctaner, deres fremstilling og anvendelse - Google Patents

Gem-dihalogen-1,8-diamino-4-azaoctaner, deres fremstilling og anvendelse Download PDF

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Publication number
DK396886A
DK396886A DK396886A DK396886A DK396886A DK 396886 A DK396886 A DK 396886A DK 396886 A DK396886 A DK 396886A DK 396886 A DK396886 A DK 396886A DK 396886 A DK396886 A DK 396886A
Authority
DK
Denmark
Prior art keywords
azaoctanes
dihalogen
gem
diamino
preparation
Prior art date
Application number
DK396886A
Other languages
Danish (da)
English (en)
Other versions
DK396886D0 (da
Inventor
Fritz Gerhart
Pierre Mamont
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of DK396886D0 publication Critical patent/DK396886D0/da
Publication of DK396886A publication Critical patent/DK396886A/da

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
    • C07C211/02—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C211/15—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton the carbon skeleton being further substituted by halogen atoms or by nitro or nitroso groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Radiology & Medical Imaging (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Indole Compounds (AREA)
  • Saccharide Compounds (AREA)
DK396886A 1985-08-21 1986-08-20 Gem-dihalogen-1,8-diamino-4-azaoctaner, deres fremstilling og anvendelse DK396886A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/767,928 US4695654A (en) 1985-08-21 1985-08-21 Gem-dihalo-1,8-diamino-4-aza-octanes

Publications (2)

Publication Number Publication Date
DK396886D0 DK396886D0 (da) 1986-08-20
DK396886A true DK396886A (da) 1987-02-22

Family

ID=25080994

Family Applications (1)

Application Number Title Priority Date Filing Date
DK396886A DK396886A (da) 1985-08-21 1986-08-20 Gem-dihalogen-1,8-diamino-4-azaoctaner, deres fremstilling og anvendelse

Country Status (20)

Country Link
US (2) US4695654A (no)
EP (1) EP0215319B1 (no)
JP (1) JPH0667880B2 (no)
KR (1) KR900006132B1 (no)
CN (1) CN1012732B (no)
AR (1) AR242018A1 (no)
AT (1) ATE68471T1 (no)
AU (1) AU584730B2 (no)
CA (1) CA1265159A (no)
DE (1) DE3682007D1 (no)
DK (1) DK396886A (no)
ES (1) ES2001108A6 (no)
FI (1) FI84816C (no)
GR (1) GR862149B (no)
HU (1) HU200987B (no)
IL (1) IL79752A0 (no)
NO (1) NO164972C (no)
NZ (1) NZ217248A (no)
PT (1) PT83231B (no)
ZA (1) ZA866181B (no)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA866180B (en) * 1985-08-21 1987-04-29 Merrell Dow Pharma Gem-dihalo and tetrahalo-1,12-diamino-4,9-diaza-dodecanes
NO884566L (no) * 1987-10-15 1989-04-17 Univ Moskovsk Anvendelse av fluorderivater og kontrastpreparat for diagnostisering av ondartede neoplasmer.
EP0338168A1 (en) * 1988-04-19 1989-10-25 Merrell Dow Pharmaceuticals Inc. Phosphonoalkylpurine derivatives
GB9301898D0 (en) * 1993-01-30 1993-03-17 Univ Liverpool Method for localising and measuring the profileration of cancer and compositions for same
US5834456A (en) * 1996-02-23 1998-11-10 The Dow Chemical Company Polyazamacrocyclofluoromonoalkylphosphonic acids, and their complexes, for use as contrast agents
CN114685325A (zh) * 2020-12-29 2022-07-01 苏州瑞博生物技术股份有限公司 一种含胺化合物及其制备方法和用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4004996A (en) * 1974-12-23 1977-01-25 Merck & Co., Inc. Fluorination of organic compounds
GB2082579B (en) * 1980-08-23 1984-02-08 Merrell Toraude & Co Fluorinated diaminobutane derivatives
US4720489A (en) * 1984-10-15 1988-01-19 Douglas Shander Hair growth modification with ornithine decarboxylase inhibitors
ZA866180B (en) * 1985-08-21 1987-04-29 Merrell Dow Pharma Gem-dihalo and tetrahalo-1,12-diamino-4,9-diaza-dodecanes

Also Published As

Publication number Publication date
ZA866181B (en) 1987-04-29
US4851448A (en) 1989-07-25
FI863352A0 (fi) 1986-08-19
KR900006132B1 (ko) 1990-08-24
CN86105154A (zh) 1987-04-22
NO863343L (no) 1987-02-23
CA1265159C (en) 1990-01-30
HU200987B (en) 1990-09-28
KR870002045A (ko) 1987-03-28
US4695654A (en) 1987-09-22
JPH0667880B2 (ja) 1994-08-31
NO863343D0 (no) 1986-08-20
ES2001108A6 (es) 1988-04-16
NO164972C (no) 1990-12-05
EP0215319A3 (en) 1988-12-14
FI863352A (fi) 1987-02-22
ATE68471T1 (de) 1991-11-15
JPS6245564A (ja) 1987-02-27
NZ217248A (en) 1989-05-29
IL79752A0 (en) 1986-11-30
GR862149B (en) 1986-12-23
PT83231A (en) 1986-09-01
CA1265159A (en) 1990-01-30
EP0215319A2 (en) 1987-03-25
HUT44753A (en) 1988-04-28
PT83231B (pt) 1988-07-01
NO164972B (no) 1990-08-27
EP0215319B1 (en) 1991-10-16
AU6155886A (en) 1987-02-26
FI84816C (fi) 1992-01-27
FI84816B (fi) 1991-10-15
AU584730B2 (en) 1989-06-01
DK396886D0 (da) 1986-08-20
CN1012732B (zh) 1991-06-05
DE3682007D1 (de) 1991-11-21
AR242018A1 (es) 1993-02-26

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