DK3930715T3 - Saracatinib til anvendelse til behandling af idiopatisk lungefibrose - Google Patents

Saracatinib til anvendelse til behandling af idiopatisk lungefibrose Download PDF

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Publication number
DK3930715T3
DK3930715T3 DK20710607.1T DK20710607T DK3930715T3 DK 3930715 T3 DK3930715 T3 DK 3930715T3 DK 20710607 T DK20710607 T DK 20710607T DK 3930715 T3 DK3930715 T3 DK 3930715T3
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DK
Denmark
Prior art keywords
saracatinib
treatment
pulmonary fibrosis
idiopathic pulmonary
idiopathic
Prior art date
Application number
DK20710607.1T
Other languages
Danish (da)
English (en)
Inventor
Leslie Cousens
Chad Nivens
Katherine Jane Escott
Susan Monkley
Antje Prasse
Original Assignee
Astrazeneca Ab
Fraunhofer Ges Forschung
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab, Fraunhofer Ges Forschung filed Critical Astrazeneca Ab
Application granted granted Critical
Publication of DK3930715T3 publication Critical patent/DK3930715T3/da

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4412Non condensed pyridines; Hydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK20710607.1T 2019-02-27 2020-02-26 Saracatinib til anvendelse til behandling af idiopatisk lungefibrose DK3930715T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962811009P 2019-02-27 2019-02-27
PCT/IB2020/051642 WO2020174420A1 (en) 2019-02-27 2020-02-26 Method of treating a fibrotic disease or condition or of an interstitial lung disease using a src kinase inhibitor

Publications (1)

Publication Number Publication Date
DK3930715T3 true DK3930715T3 (da) 2024-08-05

Family

ID=69784492

Family Applications (1)

Application Number Title Priority Date Filing Date
DK20710607.1T DK3930715T3 (da) 2019-02-27 2020-02-26 Saracatinib til anvendelse til behandling af idiopatisk lungefibrose

Country Status (12)

Country Link
US (1) US20220117966A1 (https=)
EP (1) EP3930715B1 (https=)
JP (2) JP7547356B2 (https=)
CN (1) CN113811296B (https=)
DK (1) DK3930715T3 (https=)
ES (1) ES2994095T3 (https=)
FI (1) FI3930715T3 (https=)
HU (1) HUE067967T2 (https=)
MA (1) MA55076A (https=)
PT (1) PT3930715T (https=)
TW (1) TWI836022B (https=)
WO (1) WO2020174420A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112674031B (zh) * 2020-12-03 2021-11-30 同济大学 新型冠状病毒感染的啮齿动物模型的构建方法和用途
US20250161250A1 (en) * 2022-02-28 2025-05-22 Nuformix Technologies Limited Compositions and methods for treatment of idiopathic pulmonary fibrosis
CN117618436A (zh) * 2022-08-25 2024-03-01 广州再极医药科技有限公司 一种稠环嘧啶类化合物的用途

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA73993C2 (uk) 2000-06-06 2005-10-17 Астразенека Аб Хіназолінові похідні для лікування пухлин та фармацевтична композиція
GB0427697D0 (en) 2004-12-17 2005-01-19 Astrazeneca Ab Chemical process
US9844528B2 (en) * 2006-08-24 2017-12-19 University Of Tennessee Research Foundation SARMs and method of use thereof
CN102675282B (zh) * 2011-03-15 2014-12-24 广东东阳光药业有限公司 取代的喹啉化合物及其使用方法和用途
US20130336889A1 (en) * 2012-06-14 2013-12-19 National Taiwan University Nanoparticle and method for detecting or treating a tumor using the same
CN105294682B (zh) * 2014-07-26 2017-07-07 广东东阳光药业有限公司 Cdk类小分子抑制剂的化合物及其用途
EP4653015A3 (en) * 2015-01-26 2025-12-31 Yale University COMPOSITIONS AND METHODS OF USE OF TYROSINE KINASE INHIBITORS
EP3277282B1 (en) * 2015-04-01 2022-10-12 Istanbul Universitesi Rektorlugu Dasatinib for use in the treatment, regression or decelerating the progress of fibrotic lung diseases
GB201514760D0 (en) * 2015-08-19 2015-09-30 Karus Therapeutics Ltd Compounds and method of use
JP6905662B2 (ja) * 2015-11-14 2021-07-21 サンシャイン・レイク・ファーマ・カンパニー・リミテッドSunshine Lake Pharma Co.,Ltd. 置換キノリン化合物の結晶形およびその医薬組成物
EP3228630A1 (en) * 2016-04-07 2017-10-11 IMBA-Institut für Molekulare Biotechnologie GmbH Combination of an apelin antagonist and an angiogenesis inhibitor for the treatment of cancer
WO2018026441A1 (en) * 2016-08-01 2018-02-08 The Regents Of The University Of California Methods for preventing or treating fibrotic diseases
WO2018046876A1 (en) * 2016-09-06 2018-03-15 The University Of Birmingham Treatment of chronic inflammatory disease
CN106692150B (zh) * 2016-12-21 2019-08-20 中国人民解放军第三〇二医院 尼达尼布在制备预防和治疗肝纤维化与肝硬化的药物中的用途
EP3964214A1 (en) * 2020-09-02 2022-03-09 Fraunhofer Gesellschaft zur Förderung der angewandten Forschung e.V. Modulators of airway basal cells for the treatment or prevention of lung diseases

Also Published As

Publication number Publication date
CN113811296A (zh) 2021-12-17
PT3930715T (pt) 2024-08-02
ES2994095T3 (en) 2025-01-17
MA55076A (fr) 2022-04-20
TWI836022B (zh) 2024-03-21
EP3930715B1 (en) 2024-05-08
HUE067967T2 (hu) 2024-12-28
JP2024174909A (ja) 2024-12-17
FI3930715T3 (fi) 2024-08-05
CN113811296B (zh) 2025-05-16
EP3930715A1 (en) 2022-01-05
JP2022521635A (ja) 2022-04-11
JP7547356B2 (ja) 2024-09-09
WO2020174420A1 (en) 2020-09-03
TW202045180A (zh) 2020-12-16
US20220117966A1 (en) 2022-04-21

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