DK391478A - Fremgangsmaade til fremstilling af (d-alfa-amido-(pydroxyphenyl) acetamido)-gruppeholdige penicillansyre-og-cephalosporansyrederivater - Google Patents

Fremgangsmaade til fremstilling af (d-alfa-amido-(pydroxyphenyl) acetamido)-gruppeholdige penicillansyre-og-cephalosporansyrederivater

Info

Publication number
DK391478A
DK391478A DK391478A DK391478A DK391478A DK 391478 A DK391478 A DK 391478A DK 391478 A DK391478 A DK 391478A DK 391478 A DK391478 A DK 391478A DK 391478 A DK391478 A DK 391478A
Authority
DK
Denmark
Prior art keywords
pydroxyphenyl
acetamido
alfa
amido
procedure
Prior art date
Application number
DK391478A
Other languages
English (en)
Other versions
DK151024B (da
DK151024C (da
Inventor
Peter Wolfgang Henniger
Johannes Karel Van Der Drift
Gerard Joannes Van Veen
Jagdish Chander Kapur
Original Assignee
Gist Brocades Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gist Brocades Nv filed Critical Gist Brocades Nv
Publication of DK391478A publication Critical patent/DK391478A/da
Priority to DK459383A priority Critical patent/DK152503C/da
Publication of DK151024B publication Critical patent/DK151024B/da
Application granted granted Critical
Publication of DK151024C publication Critical patent/DK151024C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK391478A 1977-09-06 1978-09-05 Fremgangsmaade til fremstilling af 6-(d-alfa-amino-(p-hydroxyphenyl)acetamido)-penicillansyre DK151024C (da)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DK459383A DK152503C (da) 1977-09-06 1983-10-05 Fremgangsmaade til fremstilling af cephalosporansyrederivater indeholdende en d-alfa-amino-(p-hydroxyphenyl)acetamidogruppe

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
NL7709812 1977-09-06
NL7709812.A NL162387C (nl) 1977-09-06 1977-09-06 Werkwijze voor het bereiden van 6-(d-alpha-amino-p- -hydroxyfenylacetamido)penicillanzuur.
EP78200140 1978-08-11
EP78200140A EP0001133B1 (en) 1977-09-06 1978-08-11 Process for the preparation of 6- d-alpha-amino-(p-hydroxyphenyl)-acetamido penicillanic acid

Publications (3)

Publication Number Publication Date
DK391478A true DK391478A (da) 1979-03-07
DK151024B DK151024B (da) 1987-10-12
DK151024C DK151024C (da) 1988-02-29

Family

ID=19829143

Family Applications (1)

Application Number Title Priority Date Filing Date
DK391478A DK151024C (da) 1977-09-06 1978-09-05 Fremgangsmaade til fremstilling af 6-(d-alfa-amino-(p-hydroxyphenyl)acetamido)-penicillansyre

Country Status (12)

Country Link
US (2) US4128547A (da)
EP (2) EP0019345B1 (da)
JP (1) JPS5495590A (da)
CA (1) CA1111413A (da)
DE (2) DE2861547D1 (da)
DK (1) DK151024C (da)
FI (1) FI70714C (da)
IE (1) IE48466B1 (da)
IT (1) IT1160632B (da)
NL (1) NL162387C (da)
NO (2) NO160209C (da)
PT (1) PT68511A (da)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1532682A (en) * 1976-04-27 1978-11-22 Bristol Myers Co Process for the preparation of cephadroxil
ES459494A1 (es) * 1977-06-04 1978-05-01 Palomo Coll A Luis Procedimiento de preparacion de hidrox-alfa-aminobencilpeni-cilina.
US4240960A (en) * 1979-03-19 1980-12-23 Bristol-Myers Company Trimethylsilyl substituted penicillins
US4278600A (en) * 1979-03-19 1981-07-14 Bristol-Myers Company Production of penicillins
US4310458A (en) * 1979-03-19 1982-01-12 Bristol-Myers Company Production of penicillins
US4231954A (en) * 1979-04-20 1980-11-04 American Home Products Corporation Dane salt and process for preparing aminopenicillins therefrom
US4301072A (en) * 1979-04-20 1981-11-17 American Home Products Corporation Process for preparing aminopenicillins
GB2052490B (en) * 1979-05-25 1983-09-07 Glaxo Group Ltd Intermediates for use in the preparation of cephalosporin antibiotics
US4351766A (en) * 1979-07-12 1982-09-28 Bristol-Myers Company Production of penicillins
IT1126544B (it) * 1979-12-07 1986-05-21 Dobfar Spa Procedimento per la preparazione di derivati dell'acido 7-amino-desacetossi cefalosporanico
NL7908867A (nl) * 1979-12-10 1981-07-01 Gist Brocades Nv Werkwijze voor het bereiden van 6-aminopenicillaanzuur- -1,1-dioxide en zijn zouten.
US4366098A (en) * 1980-11-26 1982-12-28 American Home Products Corporation Process for preparing aminopenicillins
GB2240102B (en) * 1990-01-22 1993-10-20 Biochemie Gmbh Improvements in or relating to beta lactam production
AT396238B (de) * 1991-05-17 1993-07-26 Biochemie Gmbh Neues verfahren und zwischenprodukte zur herstellung von 3-vinylcephalosporinverbindungen
AT395854B (de) * 1991-05-24 1993-03-25 Biochemie Gmbh Neues verfahren zur herstellung von 7-amino-3azidomethyl-3-cephem-4-carbonsaeure und deren derivate
GB9115203D0 (en) * 1991-07-15 1991-08-28 Biochemie Gmbh Improvements in or relating to beta lactam production
AT396108B (de) * 1991-08-21 1993-06-25 Biochemie Gmbh Neues verfahren und neue zwischenprodukte zur herstellung von 7-aminocephalosporansaeurederivaten
ES2050621B1 (es) * 1992-11-06 1994-12-16 Antibioticos Sa Un procedimiento mejorado para la preparacion de 6-*-aminopenicilinas.
GB9423459D0 (en) * 1994-11-21 1995-01-11 Biochemie Gmbh Silylation process
KR100389644B1 (ko) * 2001-02-26 2003-06-27 한미약품 주식회사 4-히드록시페닐글리신 무수물 및 이의 제조방법
US20040077849A1 (en) * 2002-10-16 2004-04-22 Orchid Chemicals & Pharmaceuticals Limited Process for the preparation of cefadroxil
US7230097B2 (en) * 2003-03-10 2007-06-12 Lupin Ltd. Process for preparation of 7-[α-Amino (4-hydroxyphenyl) acetamido]-3-substituted-3-cephem-4-carboxylic acid
EP2170909B1 (en) * 2007-07-30 2011-01-26 DSM IP Assets B.V. Process for the silylation of beta-lactam compounds
SI2176270T1 (sl) * 2007-07-30 2019-11-29 Centrient Pharmaceuticals Netherlands B V Sestavki, ki vsebujejo spojine beta laktama
CN103108879B (zh) * 2010-09-07 2016-08-17 中化帝斯曼制药有限公司荷兰公司 用于生产头孢菌素类的方法
CN103360412B (zh) * 2013-06-08 2015-08-19 苏州中联化学制药有限公司 一种头孢羟氨苄的合成方法
CN103772414B (zh) * 2013-12-31 2016-03-09 福建省福抗药业股份有限公司 一种制备丙二醇头孢曲嗪的制备方法
CN107986991A (zh) * 2017-12-18 2018-05-04 湖南国发精细化工科技有限公司 N-氯甲酰基-n[(4-三氟甲氧基)苯基]氨基甲酸甲酯的合成方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE311519B (da) * 1962-12-14 1969-06-16 Astra Ab
JPS5318515B2 (da) * 1971-12-17 1978-06-15
GB1339605A (en) * 1972-03-28 1973-12-05 Beecham Group Ltd Penicillin synthesis
CA1076560A (en) * 1972-06-14 1980-04-29 Smith Kline And French Canada Ltd. 3-heterocyclic thiomethylcephalosporins
US3965098A (en) * 1972-11-29 1976-06-22 American Home Products Corporation Intermediates for preparing cephalosporins and methods of production
KR780000197B1 (en) * 1972-12-26 1978-05-26 Bristol Myers Co Method for preparing antibacterial agent
PL87745B1 (da) * 1973-04-18 1976-07-31 Politechnika Gdanska Danzig (Polen)
YU36733B (en) * 1973-10-26 1984-08-31 Krka Novo Mesto Process for preparing pure anhydrous 6-zd-(-)-alfa-aminophenylacetamidoc-penicillanic acid
US3912719A (en) * 1974-01-28 1975-10-14 Bristol Myers Co Production of semisynthetic penicillins
NL7414083A (nl) * 1974-05-17 1975-11-19 Archifar Ind Chim Trentino Werkwijze voor de bereiding van hydroxylgroe- pen-bevattende antibiotica.
US3946003A (en) * 1974-08-20 1976-03-23 Eli Lilly And Company Hydroxy substituted phenylglycylamido-3-heterocyclic thiomethyl cephalosporins
US4148817A (en) * 1976-03-25 1979-04-10 Eli Lilly And Company Process and intermediates for preparing cephalosporin antibiotics

Also Published As

Publication number Publication date
NL162387C (nl) 1980-05-16
EP0001133A1 (en) 1979-03-21
JPS6354717B2 (da) 1988-10-28
DE2861547D1 (en) 1982-03-04
NL162387B (nl) 1979-12-17
DK151024B (da) 1987-10-12
NO160209C (no) 1989-03-22
US4128547A (en) 1978-12-05
NO854260L (no) 1979-03-07
IE781802L (en) 1979-03-06
IE48466B1 (en) 1985-02-06
EP0019345A1 (en) 1980-11-26
NO160209B (no) 1988-12-12
NL7709812A (nl) 1979-03-08
EP0001133B1 (en) 1982-01-20
FI782719A (fi) 1979-03-07
CA1111413A (en) 1981-10-27
PT68511A (en) 1978-10-01
FI70714C (fi) 1986-10-06
JPS5495590A (en) 1979-07-28
US4358588A (en) 1982-11-09
NO783025L (no) 1979-03-07
NO161495C (no) 1989-08-23
EP0019345B1 (en) 1985-06-19
DE2862468D1 (en) 1985-07-25
FI70714B (fi) 1986-06-26
IT1160632B (it) 1987-03-11
NO161495B (no) 1989-05-16
IT7869044A0 (it) 1978-09-05
DK151024C (da) 1988-02-29

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