DK3886858T3 - Forbindelser til behandling af øjensygdomme forbundet med for megen vaskularisering - Google Patents
Forbindelser til behandling af øjensygdomme forbundet med for megen vaskularisering Download PDFInfo
- Publication number
- DK3886858T3 DK3886858T3 DK20838435.4T DK20838435T DK3886858T3 DK 3886858 T3 DK3886858 T3 DK 3886858T3 DK 20838435 T DK20838435 T DK 20838435T DK 3886858 T3 DK3886858 T3 DK 3886858T3
- Authority
- DK
- Denmark
- Prior art keywords
- compounds
- treatment
- diseases associated
- eye diseases
- excessive vascularization
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title 1
- 208000030533 eye disease Diseases 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4704—2-Quinolinones, e.g. carbostyril
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
- A61K38/179—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
- A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
- A61K47/6811—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug being a protein or peptide, e.g. transferrin or bleomycin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/32—Fusion polypeptide fusions with soluble part of a cell surface receptor, "decoy receptors"
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Cell Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Ophthalmology & Optometry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Endocrinology (AREA)
- Toxicology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP19218062 | 2019-12-19 | ||
EP20156158 | 2020-02-07 | ||
PCT/EP2020/086993 WO2021123142A1 (en) | 2019-12-19 | 2020-12-18 | Compounds for treatment of eye diseases associated with excessive vascularisation |
Publications (1)
Publication Number | Publication Date |
---|---|
DK3886858T3 true DK3886858T3 (da) | 2022-08-22 |
Family
ID=74141502
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK20838435.4T DK3886858T3 (da) | 2019-12-19 | 2020-12-18 | Forbindelser til behandling af øjensygdomme forbundet med for megen vaskularisering |
Country Status (15)
Country | Link |
---|---|
US (2) | US11478465B2 (da) |
EP (2) | EP4094765A1 (da) |
JP (1) | JP2023509336A (da) |
KR (1) | KR20220118419A (da) |
CN (1) | CN114845718A (da) |
AU (1) | AU2020408179A1 (da) |
BR (1) | BR112022009192A2 (da) |
CA (1) | CA3157394A1 (da) |
DK (1) | DK3886858T3 (da) |
ES (1) | ES2921360T3 (da) |
IL (1) | IL293469B2 (da) |
MX (1) | MX2022006439A (da) |
PL (1) | PL3886858T3 (da) |
WO (1) | WO2021123142A1 (da) |
ZA (1) | ZA202204939B (da) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2020408179A1 (en) * | 2019-12-19 | 2022-06-30 | Active Biotech Ab | Compounds for treatment of eye diseases associated with excessive vascularisation |
WO2022207773A1 (en) | 2021-04-01 | 2022-10-06 | Active Biotech Ab | Laquinimod formulation for ocular use |
Family Cites Families (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6077851A (en) | 1998-04-27 | 2000-06-20 | Active Biotech Ab | Quinoline derivatives |
SE9801474D0 (sv) | 1998-04-27 | 1998-04-27 | Active Biotech Ab | Quinoline Derivatives |
US6875869B2 (en) | 2002-06-12 | 2005-04-05 | Active Biotech Ab | Process for the manufacture of quinoline derivatives |
US9265725B2 (en) | 2002-10-25 | 2016-02-23 | Foamix Pharmaceuticals Ltd. | Dicarboxylic acid foamable vehicle and pharmaceutical compositions thereof |
WO2008124828A1 (en) * | 2007-04-10 | 2008-10-16 | Myriad Genetics, Inc. | Methods for treating vascular disruption disorders |
EP2376456A2 (en) | 2008-12-17 | 2011-10-19 | Actavis Group Ptc Ehf | Highly pure laquinimod or a pharmaceutically acceptable salt thereof |
CN102984939A (zh) * | 2010-07-09 | 2013-03-20 | 泰华制药工业有限公司 | 氘化的n-乙基-n-苯基-1,2-二氢-4-羟基-5-氯-1-甲基-2-氧代喹啉-3-甲酰胺、其盐和用途 |
EP2463289A1 (en) | 2010-11-26 | 2012-06-13 | Almirall, S.A. | Imidazo[1,2-b]pyridazine derivatives as JAK inhibitors |
EP2527344A1 (en) | 2011-05-25 | 2012-11-28 | Almirall, S.A. | Pyridin-2(1H)-one derivatives useful as medicaments for the treatment of myeloproliferative disorders, transplant rejection, immune-mediated and inflammatory diseases |
EP2537517A1 (en) * | 2011-06-22 | 2012-12-26 | Active Biotech AB | Deuterium-enriched 4-hydroxy-5-methoxy-n,1-dimethyl-2-oxo-n-[(4-trifluoro-methyl)phenyl]-1,2-dihydroquinoline-3-carboxamide |
EA201490377A1 (ru) | 2011-07-28 | 2014-11-28 | Тева Фармасьютикал Индастриз Лтд. | Лечение рассеянного склероза комбинацией лаквинимода и глатирамера ацетата |
TW201400117A (zh) * | 2012-06-05 | 2014-01-01 | Teva Pharma | 使用拉喹莫德治療眼發炎疾病 |
CN104884049A (zh) * | 2012-11-08 | 2015-09-02 | 克莱尔塞德生物医学股份有限公司 | 用于在人类受试者中治疗眼部疾病的方法和装置 |
WO2015060812A1 (en) | 2013-10-21 | 2015-04-30 | Howard University | Treating ocular disease with efflux transporter inhibitors |
US20160310417A1 (en) * | 2013-12-20 | 2016-10-27 | Emory University | Formulations and Methods For Targeted Ocular Delivery of Therapeutic Agents |
WO2017120355A1 (en) | 2016-01-06 | 2017-07-13 | Teva Pharmaceutical Industries Ltd. | Dihydroquinolines and uses thereof |
EP3654941A1 (en) * | 2017-07-17 | 2020-05-27 | Keith Roizman | Topical delivery of therapeutic agents comprising cell-penetrating peptides for use for the treatment of age-related macular degeneration and other eye diseases |
US10759807B2 (en) | 2017-12-22 | 2020-09-01 | Chemocentryx, Inc. | Diaryl substituted 5,5-fused ring compounds as C5aR inhibitors |
AU2018388655C1 (en) | 2017-12-22 | 2023-03-23 | Chemocentryx, Inc. | Diaryl substituted 6,5-fused ring compounds as C5aR inhibitors |
US11608336B2 (en) | 2018-04-02 | 2023-03-21 | Chemocentryx, Inc. | Prodrugs of fused-bicyclic C5aR antagonists |
AU2020408179A1 (en) * | 2019-12-19 | 2022-06-30 | Active Biotech Ab | Compounds for treatment of eye diseases associated with excessive vascularisation |
-
2020
- 2020-12-18 AU AU2020408179A patent/AU2020408179A1/en active Pending
- 2020-12-18 BR BR112022009192A patent/BR112022009192A2/pt unknown
- 2020-12-18 PL PL20838435.4T patent/PL3886858T3/pl unknown
- 2020-12-18 MX MX2022006439A patent/MX2022006439A/es unknown
- 2020-12-18 DK DK20838435.4T patent/DK3886858T3/da active
- 2020-12-18 IL IL293469A patent/IL293469B2/en unknown
- 2020-12-18 EP EP22167643.0A patent/EP4094765A1/en active Pending
- 2020-12-18 EP EP20838435.4A patent/EP3886858B1/en active Active
- 2020-12-18 ES ES20838435T patent/ES2921360T3/es active Active
- 2020-12-18 JP JP2022535637A patent/JP2023509336A/ja active Pending
- 2020-12-18 KR KR1020227019983A patent/KR20220118419A/ko unknown
- 2020-12-18 WO PCT/EP2020/086993 patent/WO2021123142A1/en active Application Filing
- 2020-12-18 CN CN202080087752.XA patent/CN114845718A/zh active Pending
- 2020-12-18 CA CA3157394A patent/CA3157394A1/en active Pending
-
2021
- 2021-07-02 US US17/366,979 patent/US11478465B2/en active Active
-
2022
- 2022-05-05 ZA ZA2022/04939A patent/ZA202204939B/en unknown
- 2022-09-07 US US17/939,109 patent/US20230066364A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
ZA202204939B (en) | 2023-12-20 |
IL293469A (en) | 2022-08-01 |
US11478465B2 (en) | 2022-10-25 |
CA3157394A1 (en) | 2021-06-24 |
EP3886858B1 (en) | 2022-05-11 |
IL293469B2 (en) | 2024-04-01 |
MX2022006439A (es) | 2022-07-19 |
US20210322400A1 (en) | 2021-10-21 |
IL293469B1 (en) | 2023-12-01 |
EP4094765A1 (en) | 2022-11-30 |
KR20220118419A (ko) | 2022-08-25 |
JP2023509336A (ja) | 2023-03-08 |
BR112022009192A2 (pt) | 2022-07-26 |
EP3886858A1 (en) | 2021-10-06 |
CN114845718A (zh) | 2022-08-02 |
PL3886858T3 (pl) | 2022-08-29 |
ES2921360T3 (es) | 2022-08-24 |
US20230066364A1 (en) | 2023-03-02 |
AU2020408179A1 (en) | 2022-06-30 |
WO2021123142A1 (en) | 2021-06-24 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK3728271T3 (da) | Makrocykliske forbindelser til behandling af sygdomme | |
DK3347030T3 (da) | Brug af pasteuriseret akkermansia til behandling af stofskiftesygdomme | |
DK3399962T3 (da) | Oftalmisk sammensætning til behandling af tør øjensygdom | |
DK3386511T3 (da) | Fremgangsmåder til behandling af huntingtons sygdom | |
DK3681500T3 (da) | Anvendelse af pilocarpinhydrochlorid til behandling af presbyopi | |
DK3516060T3 (da) | Antisense-oligonukleotider til behandling af øjensygdom | |
DK3668509T3 (da) | Fremgangsmåde til behandling af amyotrofisk lateralsklerose med pridopidin | |
DK3865484T3 (da) | Pde9-hæmmer med imidazopyrazinon-rygrad til behandling af perifere sygdomme | |
DK3240538T3 (da) | Anvendelse af masitinib til behandling af en underpopulation af patienter med amyotrofisk lateralsklerose | |
DK3288577T3 (da) | Adiponectin-peptidomimetika til behandling af øjenlidelser | |
DK3498278T3 (da) | Forbindelser til behandling af sygdomme relateret til DUX4-ekspression | |
DK3612208T3 (da) | Coversin til behandlingen af autoimmune sygdomme med blisterdannelse | |
DK3548061T3 (da) | Behandling af neurologiske sygdomme | |
DK3720433T3 (da) | Bis-cholin-tetrathiomolybdat til behandling af wilsons sygdom | |
DK3870578T3 (da) | Terapeutiske forbindelser | |
DK3439661T3 (da) | Fremgangsmåder til behandling af øjenlidelser | |
DK3419622T3 (da) | Behandling af neurodegenerativ øjensygdom med pridopidin | |
DK3210973T3 (da) | Heteroarylforbindelser til behandling af oftalmiske sygdomme | |
DK3897672T3 (da) | Hbv kombinationsbehandling | |
DK3097085T3 (da) | Benzoxazinonderivater til behandling af hudsygdomme | |
DK3773558T3 (da) | Kombinationsbehandling af artritisk sygdom | |
DK3833746T3 (da) | Mini-gde til behandlingen af glykogenlagringssygdom iii | |
DK3578562T3 (da) | L-valinatamidbenzoxaborolderivater til behandling af parasitiske sygdomme | |
DK3432895T3 (da) | Blodpladepelletlysat til anvendelse til behandling af neurologiske forstyrrelser | |
GB2541840B (en) | Ophthalmic composition for the treatment of ocular infection |