DK3692173T3 - Vurdering af cellulær jak-stat1/2-signalvejsaktivitet under anvendelse af matematisk modellering af målgenekspression - Google Patents
Vurdering af cellulær jak-stat1/2-signalvejsaktivitet under anvendelse af matematisk modellering af målgenekspression Download PDFInfo
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- DK3692173T3 DK3692173T3 DK18773226.8T DK18773226T DK3692173T3 DK 3692173 T3 DK3692173 T3 DK 3692173T3 DK 18773226 T DK18773226 T DK 18773226T DK 3692173 T3 DK3692173 T3 DK 3692173T3
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6851—Quantitative amplification
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
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- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06N—COMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
- G06N7/00—Computing arrangements based on specific mathematical models
- G06N7/01—Probabilistic graphical models, e.g. probabilistic networks
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B5/00—ICT specially adapted for modelling or simulations in systems biology, e.g. gene-regulatory networks, protein interaction networks or metabolic networks
- G16B5/20—Probabilistic models
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B50/00—ICT programming tools or database systems specially adapted for bioinformatics
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
- G16B25/10—Gene or protein expression profiling; Expression-ratio estimation or normalisation
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- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Theoretical Computer Science (AREA)
- Bioinformatics & Computational Biology (AREA)
- Medical Informatics (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Evolutionary Biology (AREA)
- Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Probability & Statistics with Applications (AREA)
- Oncology (AREA)
- General Physics & Mathematics (AREA)
- Physiology (AREA)
- Hospice & Palliative Care (AREA)
- Mathematical Analysis (AREA)
- Databases & Information Systems (AREA)
- Bioethics (AREA)
- Algebra (AREA)
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- Mathematical Optimization (AREA)
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP17194291.5A EP3461915A1 (en) | 2017-10-02 | 2017-10-02 | Assessment of jak-stat1/2 cellular signaling pathway activity using mathematical modelling of target gene expression |
| PCT/EP2018/076334 WO2019068562A1 (en) | 2017-10-02 | 2018-09-27 | EVALUATION OF THE ACTIVITY OF THE JAK-STAT1 / 2 CELL SIGNALING PATH USING MATHEMATICAL MODELING OF A TARGET GENE EXPRESSION |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3692173T3 true DK3692173T3 (da) | 2021-05-31 |
Family
ID=60037387
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK18773226.8T DK3692173T3 (da) | 2017-10-02 | 2018-09-27 | Vurdering af cellulær jak-stat1/2-signalvejsaktivitet under anvendelse af matematisk modellering af målgenekspression |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US11649488B2 (da) |
| EP (2) | EP3461915A1 (da) |
| JP (1) | JP6931125B2 (da) |
| CN (1) | CN111479933A (da) |
| CA (1) | CA3078278A1 (da) |
| DK (1) | DK3692173T3 (da) |
| ES (1) | ES2868887T3 (da) |
| WO (1) | WO2019068562A1 (da) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3882363A1 (en) | 2020-03-17 | 2021-09-22 | Koninklijke Philips N.V. | Prognostic pathways for high risk sepsis patients |
| EP3978628A1 (en) | 2020-10-01 | 2022-04-06 | Koninklijke Philips N.V. | Prognostic pathways for viral infections |
| EP4136261A1 (en) | 2020-04-16 | 2023-02-22 | InnoSIGN B.V. | Prognostic pathways for viral infections |
| EP3940704A1 (en) * | 2020-07-14 | 2022-01-19 | Koninklijke Philips N.V. | Method for determining the differentiation state of a stem cell |
| EP3960875A1 (en) | 2020-08-28 | 2022-03-02 | Koninklijke Philips N.V. | Pcr method and kit for determining pathway activity |
| EP3974540A1 (en) | 2020-09-25 | 2022-03-30 | Koninklijke Philips N.V. | Method for predicting immunotherapy resistance |
| EP4015651A1 (en) | 2020-12-17 | 2022-06-22 | Koninklijke Philips N.V. | Treatment prediction and effectiveness of anti-tnf alpha treatment in ibd patients |
| EP4039825A1 (en) | 2021-02-09 | 2022-08-10 | Koninklijke Philips N.V. | Comparison and standardization of cell and tissue culture |
| JP2024514404A (ja) | 2021-03-11 | 2024-04-02 | コーニンクレッカ フィリップス エヌ ヴェ | 高リスク敗血症患者のための予後経路 |
Family Cites Families (51)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4711955A (en) | 1981-04-17 | 1987-12-08 | Yale University | Modified nucleotides and methods of preparing and using same |
| US6004761A (en) | 1986-11-19 | 1999-12-21 | Sanofi | Method for detecting cancer using monoclonal antibodies to new mucin epitopes |
| US5660985A (en) | 1990-06-11 | 1997-08-26 | Nexstar Pharmaceuticals, Inc. | High affinity nucleic acid ligands containing modified nucleotides |
| US5436134A (en) | 1993-04-13 | 1995-07-25 | Molecular Probes, Inc. | Cyclic-substituted unsymmetrical cyanine dyes |
| US5658751A (en) | 1993-04-13 | 1997-08-19 | Molecular Probes, Inc. | Substituted unsymmetrical cyanine dyes with selected permeability |
| US6720149B1 (en) | 1995-06-07 | 2004-04-13 | Affymetrix, Inc. | Methods for concurrently processing multiple biological chip assays |
| US5545531A (en) | 1995-06-07 | 1996-08-13 | Affymax Technologies N.V. | Methods for making a device for concurrently processing multiple biological chip assays |
| US6146897A (en) | 1995-11-13 | 2000-11-14 | Bio-Rad Laboratories | Method for the detection of cellular abnormalities using Fourier transform infrared spectroscopy |
| US6391550B1 (en) | 1996-09-19 | 2002-05-21 | Affymetrix, Inc. | Identification of molecular sequence signatures and methods involving the same |
| NZ516848A (en) | 1997-06-20 | 2004-03-26 | Ciphergen Biosystems Inc | Retentate chromatography apparatus with applications in biology and medicine |
| DE69823206T2 (de) | 1997-07-25 | 2004-08-19 | Affymetrix, Inc. (a Delaware Corp.), Santa Clara | Verfahren zur herstellung einer bio-informatik-datenbank |
| US6953662B2 (en) | 1997-08-29 | 2005-10-11 | Human Genome Sciences, Inc. | Follistatin-3 |
| US6020135A (en) | 1998-03-27 | 2000-02-01 | Affymetrix, Inc. | P53-regulated genes |
| US6884578B2 (en) | 2000-03-31 | 2005-04-26 | Affymetrix, Inc. | Genes differentially expressed in secretory versus proliferative endometrium |
| US6783934B1 (en) | 2000-05-01 | 2004-08-31 | Cepheid, Inc. | Methods for quantitative analysis of nucleic acid amplification reaction |
| CN1262337C (zh) | 2000-11-16 | 2006-07-05 | 赛弗根生物系统股份有限公司 | 质谱分析方法 |
| AU2002314715B2 (en) | 2001-02-16 | 2006-07-27 | Ciphergen Biosystems, Inc. | Method for correlating gene expression profiles with protein expression profiles |
| JP2005519624A (ja) | 2002-03-13 | 2005-07-07 | ジェノミック ヘルス， インコーポレイテッド | 生検腫瘍組織での遺伝子発現プロファイリング |
| US7097976B2 (en) | 2002-06-17 | 2006-08-29 | Affymetrix, Inc. | Methods of analysis of allelic imbalance |
| JP4606879B2 (ja) | 2002-11-15 | 2011-01-05 | ジェノミック ヘルス， インコーポレイテッド | Ｅｇｆｒ陽性癌の遺伝子発現プロファイリング |
| US20040231909A1 (en) | 2003-01-15 | 2004-11-25 | Tai-Yang Luh | Motorized vehicle having forward and backward differential structure |
| PL3470535T3 (pl) | 2003-06-24 | 2020-08-24 | Genomic Health, Inc. | Prognozowanie prawdopodobieństwa ponownego wystąpienia raka |
| US7526387B2 (en) | 2003-07-10 | 2009-04-28 | Genomic Health, Inc. | Expression profile algorithm and test for cancer prognosis |
| JP2005176804A (ja) | 2003-12-24 | 2005-07-07 | Japan Health Science Foundation | Ｓｔａｔ３の活性化能を指標とする肝疾患治療剤のスクリーニング法 |
| CA3061785A1 (en) | 2004-11-05 | 2006-05-18 | Genomic Health, Inc. | Predicting response to chemotherapy using gene expression markers |
| CA2602951A1 (en) | 2005-03-23 | 2006-09-28 | Bio-Rad Laboratories, Inc. | Diverse chemical libraries bound to small particles with paramagnetic properties |
| US7919261B2 (en) | 2005-12-05 | 2011-04-05 | Merck Sharp & Dohme Corp. | Methods for predicting treatment response based on the expression profiles of protein and transcription biomarkers |
| KR100806274B1 (ko) | 2005-12-06 | 2008-02-22 | 한국전자통신연구원 | 멀티 쓰레디드 프로세서 기반의 병렬 시스템을 위한 적응형실행 방법 |
| JP5297202B2 (ja) | 2006-01-11 | 2013-09-25 | ジェノミック ヘルス， インコーポレイテッド | 結腸直腸癌の予後のための遺伝子発現マーカー |
| US7888019B2 (en) | 2006-03-31 | 2011-02-15 | Genomic Health, Inc. | Genes involved estrogen metabolism |
| US8518639B2 (en) | 2006-04-11 | 2013-08-27 | Bio-Rad Innovations | HPV detection and quantification by real-time multiplex amplification |
| CA2706881A1 (en) | 2007-11-30 | 2009-06-11 | Brian Z. Ring | Tle3 as a marker for chemotherapy |
| WO2009114836A1 (en) | 2008-03-14 | 2009-09-17 | Genomic Health, Inc. | Gene expression markers for prediction of patient response to chemotherapy |
| GB2477705B (en) | 2008-11-17 | 2014-04-23 | Veracyte Inc | Methods and compositions of molecular profiling for disease diagnostics |
| US8765383B2 (en) | 2009-04-07 | 2014-07-01 | Genomic Health, Inc. | Methods of predicting cancer risk using gene expression in premalignant tissue |
| WO2011014697A1 (en) | 2009-07-31 | 2011-02-03 | The Translational Genomics Research Institute | Methods of assessing a risk of cancer progression |
| US8451450B2 (en) | 2009-09-14 | 2013-05-28 | Bio-Rad Laboratories, Inc. | Near real time optical phase conjugation |
| WO2011146619A2 (en) | 2010-05-19 | 2011-11-24 | The Regents Of The University Of California | Systems and methods for identifying drug targets using biological networks |
| US8703736B2 (en) | 2011-04-04 | 2014-04-22 | The Translational Genomics Research Institute | Therapeutic target for pancreatic cancer cells |
| US20130042333A1 (en) * | 2011-05-06 | 2013-02-14 | Jean-Gabriel JUDDE | Markers for cancer prognosis and therapy and methods of use |
| KR20140044341A (ko) | 2011-06-02 | 2014-04-14 | 알막 다이아그노스틱스 리미티드 | 암에 대한 분자적 진단 검사 |
| EP2549399A1 (en) | 2011-07-19 | 2013-01-23 | Koninklijke Philips Electronics N.V. | Assessment of Wnt pathway activity using probabilistic modeling of target gene expression |
| MX366164B (es) | 2012-01-31 | 2019-07-01 | Genomic Health Inc | Algoritmo de perfil de expresion genica y prueba para determinar la prognosis de cancer de prostata. |
| US10081838B2 (en) | 2012-05-03 | 2018-09-25 | Qiagen Sciences, Llc | Gene expression signature for IL-6/STAT3 signaling pathway and use thereof |
| RU2721130C2 (ru) * | 2012-12-26 | 2020-05-18 | Конинклейке Филипс Н.В. | Оценка активности путей клеточной сигнализации с помощью линейной комбинации(ий) экспрессий генов-мишеней |
| KR102256141B1 (ko) | 2013-04-26 | 2021-05-27 | 코닌클리케 필립스 엔.브이. | 다수의 세포 신호전달 경로 활성을 이용하는 치료 반응의 의학적 예후 및 예측 |
| WO2015050844A1 (en) | 2013-10-01 | 2015-04-09 | Dana-Farber Cancer Institute, Inc. | Methods of treating cancer with atovaquone-related compounds |
| JP6077178B2 (ja) * | 2014-01-03 | 2017-02-08 | コーニンクレッカ フィリップス エヌ ヴェＫｏｎｉｎｋｌｉｊｋｅ Ｐｈｉｌｉｐｓ Ｎ．Ｖ． | 標的遺伝子発現の数学的モデリングを用いるｐｉ３ｋ細胞内シグナル伝達経路活性の評価 |
| JP6704861B2 (ja) | 2014-06-16 | 2020-06-03 | ワールドワイド・イノベイティブ・ネットワークＷｏｒｌｄｗｉｄｅ Ｉｎｎｏｖａｔｉｖｅ Ｎｅｔｗｏｒｋ | 癌処置のための個別化三剤治療を選択するための方法 |
| EP3210144B1 (en) * | 2014-10-24 | 2020-10-21 | Koninklijke Philips N.V. | Medical prognosis and prediction of treatment response using multiple cellular signaling pathway activities |
| AU2015334840B2 (en) * | 2014-10-24 | 2021-10-21 | Innosign B.V. | Assessment of TGF-beta cellular signaling pathway activity using mathematical modelling of target gene expression |
-
2017
- 2017-10-02 EP EP17194291.5A patent/EP3461915A1/en not_active Withdrawn
-
2018
- 2018-09-27 ES ES18773226T patent/ES2868887T3/es active Active
- 2018-09-27 JP JP2020518644A patent/JP6931125B2/ja active Active
- 2018-09-27 US US16/143,885 patent/US11649488B2/en active Active
- 2018-09-27 DK DK18773226.8T patent/DK3692173T3/da active
- 2018-09-27 WO PCT/EP2018/076334 patent/WO2019068562A1/en unknown
- 2018-09-27 CN CN201880077510.5A patent/CN111479933A/zh active Pending
- 2018-09-27 EP EP18773226.8A patent/EP3692173B1/en active Active
- 2018-09-27 CA CA3078278A patent/CA3078278A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP2020535822A (ja) | 2020-12-10 |
| EP3461915A1 (en) | 2019-04-03 |
| ES2868887T3 (es) | 2021-10-22 |
| JP6931125B2 (ja) | 2021-09-01 |
| EP3692173A1 (en) | 2020-08-12 |
| CA3078278A1 (en) | 2019-04-11 |
| US11649488B2 (en) | 2023-05-16 |
| US20190100795A1 (en) | 2019-04-04 |
| CN111479933A (zh) | 2020-07-31 |
| WO2019068562A1 (en) | 2019-04-11 |
| EP3692173B1 (en) | 2021-03-31 |
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