DK368287A - Substituerede amino-5,6,7,8-tetrahydronaphthyloxy-eddikesyrer, fremgangsmaader til deres fremstilling og deres anvendelse som laegemidler - Google Patents

Substituerede amino-5,6,7,8-tetrahydronaphthyloxy-eddikesyrer, fremgangsmaader til deres fremstilling og deres anvendelse som laegemidler

Info

Publication number
DK368287A
DK368287A DK368287A DK368287A DK368287A DK 368287 A DK368287 A DK 368287A DK 368287 A DK368287 A DK 368287A DK 368287 A DK368287 A DK 368287A DK 368287 A DK368287 A DK 368287A
Authority
DK
Denmark
Prior art keywords
tetrahydronaphthyloxy
medicines
procedures
preparation
substituted amino
Prior art date
Application number
DK368287A
Other languages
English (en)
Other versions
DK368287D0 (da
Inventor
Ulrich Niewoehner
Franz-Peter Hoever
Bodo Junge
Elisabeth Perzborn
Friedel Seuter
Volker-Bernd Fiedler
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of DK368287D0 publication Critical patent/DK368287D0/da
Publication of DK368287A publication Critical patent/DK368287A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C217/64—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains further substituted by singly-bound oxygen atoms
    • C07C217/66—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains further substituted by singly-bound oxygen atoms with singly-bound oxygen atoms and six-membered aromatic rings bound to the same carbon atom of the carbon chain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • C07D213/82—Amides; Imides in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/02—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions involving the formation of amino groups from compounds containing hydroxy groups or etherified or esterified hydroxy groups
DK368287A 1986-07-16 1987-07-15 Substituerede amino-5,6,7,8-tetrahydronaphthyloxy-eddikesyrer, fremgangsmaader til deres fremstilling og deres anvendelse som laegemidler DK368287A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3623941A DE3623941A1 (de) 1986-07-16 1986-07-16 Substituierte amino-5,6,7,8-tetrahydronaphthyl-oxyessigsaeuren, verfahren zu deren herstellung sowie die verwendung als arzneimittel

Publications (2)

Publication Number Publication Date
DK368287D0 DK368287D0 (da) 1987-07-15
DK368287A true DK368287A (da) 1988-01-17

Family

ID=6305262

Family Applications (1)

Application Number Title Priority Date Filing Date
DK368287A DK368287A (da) 1986-07-16 1987-07-15 Substituerede amino-5,6,7,8-tetrahydronaphthyloxy-eddikesyrer, fremgangsmaader til deres fremstilling og deres anvendelse som laegemidler

Country Status (17)

Country Link
US (2) US4868331A (da)
EP (1) EP0253257B1 (da)
JP (1) JPS6323847A (da)
KR (1) KR890001951A (da)
CN (1) CN87104970A (da)
AT (1) ATE58372T1 (da)
AU (1) AU591999B2 (da)
DE (2) DE3623941A1 (da)
DK (1) DK368287A (da)
FI (1) FI873112A (da)
GR (1) GR3002529T3 (da)
HU (1) HU198442B (da)
IL (1) IL83162A0 (da)
NO (1) NO872784L (da)
NZ (1) NZ221043A (da)
PH (1) PH24956A (da)
ZA (1) ZA875168B (da)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3642105A1 (de) * 1986-12-10 1988-06-16 Bayer Ag Substituierte aminomethyl-5,6,7,8-tetrahydronaphtyl-oxyessigsaeuren, neue zwischenprodukte, verfahren zu ihrer herstellung sowie ihre verwendung in arzneimitteln
US5235103A (en) * 1987-08-12 1993-08-10 Sanofi Process for the preparation of phenylethanolaminotetralins
FR2619378B1 (fr) * 1987-08-12 1989-12-15 Midy Spa Procede pour la preparation de phenylethanolaminotetralines
ES2045164T3 (es) * 1987-08-12 1994-01-16 Sanofi Elf Procedimiento para la preparacion de feniletanolaminotetralinas.
FR2632637B1 (fr) * 1988-06-14 1990-10-12 Midy Spa Ethers de la 2-amino-7-hydroxytetraline
US5198586A (en) * 1987-08-12 1993-03-30 Sanofi Process for the preparation of phenylethanolaminotetralins
FR2632636B1 (fr) * 1988-06-14 1991-03-22 Midy Spa Procede pour la preparation de phenylethanolaminotetralines
US4959383A (en) * 1988-10-31 1990-09-25 E. R. Squibb & Sons, Inc. Phenylsulfone alkenoic acids, derivatives thereof, compositions containing same and method of use
US5006542A (en) * 1988-10-31 1991-04-09 E. R. Squibb & Sons, Inc. Arylthioalkylphenyl carboxylic acids, derivatives thereof, compositions containing same and method of use
US5070099A (en) * 1988-10-31 1991-12-03 E. R. Squibb & Sons, Inc. Arylthioalkylphenyl carboxylic acids, derivatives thereof, compositions containing same method of use
FR2643076B1 (fr) * 1989-02-14 1991-06-21 Midy Spa Carboxyalkyl-ethers de la 2-amino-7-hydroxytetraline
US5312961A (en) * 1989-02-14 1994-05-17 Elf Sanofi 2-amino-7-hydroxytetralin carboxylalkyl ethers
US5071875A (en) * 1989-09-25 1991-12-10 Northwestern University Substituted 2-amidotetralins as melatonin agonists and antagonists
US5264458A (en) * 1989-11-02 1993-11-23 Bayer Aktiengesellschaft Antithrombotic iso- and heterocyclic phenylsulphonamides
GB8924755D0 (en) * 1989-11-02 1989-12-20 Bayer Ag Iso-and heterocyclic phenylsulphonylamides
US5206428A (en) * 1989-11-16 1993-04-27 Tanabe Seiyaku Co., Ltd. Tetrahydronaphthalene derivatives and preparation thereof
US5206418A (en) * 1989-11-16 1993-04-27 Tanabe Seiyaku Co., Ltd. Amino-tetrahydronaphthalene derivatives
EP0450238A1 (en) * 1990-03-30 1991-10-09 Merrell Dow Pharmaceuticals Inc. Novel compounds for the treatment of migraine
FR2711139B1 (fr) * 1993-10-15 1995-12-01 Adir Nouveaux dérivés de 1,2,3,4-tétrahydronaphtalène, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.
ES2118333T3 (es) * 1993-12-09 1998-09-16 Ono Pharmaceutical Co Derivados del acido naftilacetico como agonistas y antagonistas de pgez.
FR2809725B1 (fr) * 2000-06-06 2004-05-07 Sanofi Synthelabo Propanolaminotetralines, leur preparation et compositions pharmaceutiques en contenant
PE20020856A1 (es) * 2001-02-13 2002-11-11 Aventis Pharma Gmbh 1,2,3,4-tetrahidronaftil aminas aciladas
CA2730390A1 (en) 2008-07-15 2010-01-21 F.Hoffmann-La Roche Ag Aminotetrahydroindazoloacetic acids
CA2728311A1 (en) 2008-07-15 2010-01-21 F. Hoffmann-La Roche Ag Aminotetrahydroindazoloacetic acids
JP5302401B2 (ja) * 2008-08-15 2013-10-02 エフ．ホフマン−ラ ロシュ アーゲー モノアリールアミノテトラリン
JP2012500189A (ja) * 2008-08-15 2012-01-05 エフ．ホフマン−ラ ロシュ アーゲー ビアリールアミノテトラリン
CN102066317A (zh) * 2008-08-15 2011-05-18 霍夫曼-拉罗奇有限公司 取代的氨基四氢化萘
CA2740863A1 (en) * 2008-11-17 2010-05-20 F. Hoffmann-La Roche Ag Naphthylacetic acids
PE20110710A1 (es) * 2008-11-17 2011-10-13 Hoffmann La Roche Acidos naftilaceticos
WO2010055006A1 (en) * 2008-11-17 2010-05-20 F. Hoffmann-La Roche Ag Naphthylacetic acids used as crth2 antagonists or partial agonists
US8470884B2 (en) 2011-11-09 2013-06-25 Hoffmann-La Roche Inc. Alkenyl naphthylacetic acids
US9000044B2 (en) 2012-02-28 2015-04-07 Hoffmann-La Roche Inc. Substituted naphthylacetic acids
US9643919B2 (en) 2013-04-04 2017-05-09 The Trustees Of The University Of Pennsylvania Cycloalkyl-dione derivatives and methods of their use
CN106380408A (zh) * 2016-09-04 2017-02-08 王际菊 一种光学纯手性胺的制备方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL285498A (da) * 1961-11-14
US3829467A (en) * 1972-07-03 1974-08-13 Rorer Inc William H Tetrahydronaphthylalkanoic acids and their derivatives
JPS561305B2 (da) * 1972-12-18 1981-01-13
DK254975A (da) * 1974-06-12 1975-12-13 Takeda Chemical Industries Ltd Fremgangsmade til fremstilling af aminotetralolforbindelser
FR2407198A1 (fr) * 1977-10-27 1979-05-25 Torii & Co Ltd Esters amino- ou guanidino-1, 2, 3, 4-tetrahydro-1-naphtoiques
DE2809377A1 (de) * 1978-03-04 1979-09-13 Boehringer Mannheim Gmbh Phenoxyalkylcarbonsaeure-derivate, verfahren zu deren herstellung sowie diese verbindungen enthaltende arzneimittel
EP0026848B1 (de) * 1979-09-14 1983-05-04 Sandoz Ag Tetralinderivate, ihre Herstellung und Heilmittel, welche diese Verbindungen enthalten
JPS5970653A (ja) * 1982-10-15 1984-04-21 Takeda Chem Ind Ltd 眼圧低下剤
IL79323A (en) * 1985-07-10 1990-03-19 Sanofi Sa Phenylethanolaminotetralines,their preparation and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
NO872784L (no) 1988-01-18
NO872784D0 (no) 1987-07-02
PH24956A (en) 1990-12-26
DK368287D0 (da) 1987-07-15
GR3002529T3 (en) 1993-01-25
US4868331A (en) 1989-09-19
US4921998A (en) 1990-05-01
FI873112A (fi) 1988-01-17
JPS6323847A (ja) 1988-02-01
HU198442B (en) 1989-10-30
EP0253257B1 (de) 1990-11-14
CN87104970A (zh) 1988-02-03
NZ221043A (en) 1990-06-26
EP0253257A2 (de) 1988-01-20
KR890001951A (ko) 1989-04-06
ZA875168B (en) 1988-03-30
DE3766172D1 (de) 1990-12-20
IL83162A0 (en) 1987-12-31
AU7569687A (en) 1988-01-21
EP0253257A3 (en) 1988-11-30
FI873112A0 (fi) 1987-07-14
AU591999B2 (en) 1989-12-21
DE3623941A1 (de) 1988-01-28
HUT45489A (en) 1988-07-28
ATE58372T1 (de) 1990-11-15

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