DK35687A - Isoquinolinderivater og fremgangsmaade til fremstilling deraf - Google Patents
Isoquinolinderivater og fremgangsmaade til fremstilling derafInfo
- Publication number
- DK35687A DK35687A DK035687A DK35687A DK35687A DK 35687 A DK35687 A DK 35687A DK 035687 A DK035687 A DK 035687A DK 35687 A DK35687 A DK 35687A DK 35687 A DK35687 A DK 35687A
- Authority
- DK
- Denmark
- Prior art keywords
- procedures
- preparing
- isoquinoline derivatives
- isoquinoline
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
- C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pain & Pain Management (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB868601796A GB8601796D0 (en) | 1986-01-24 | 1986-01-24 | Compounds |
Publications (2)
Publication Number | Publication Date |
---|---|
DK35687D0 DK35687D0 (da) | 1987-01-22 |
DK35687A true DK35687A (da) | 1987-07-25 |
Family
ID=10591914
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK035687A DK35687A (da) | 1986-01-24 | 1987-01-22 | Isoquinolinderivater og fremgangsmaade til fremstilling deraf |
Country Status (10)
Country | Link |
---|---|
US (1) | US4806547A (ja) |
EP (1) | EP0232989B1 (ja) |
JP (1) | JPH0780855B2 (ja) |
AU (1) | AU595281B2 (ja) |
DE (1) | DE3772218D1 (ja) |
DK (1) | DK35687A (ja) |
GB (1) | GB8601796D0 (ja) |
NZ (1) | NZ219030A (ja) |
PT (1) | PT84187B (ja) |
ZA (1) | ZA87467B (ja) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3670080D1 (de) * | 1985-12-23 | 1990-05-10 | Zambeletti Spa L | Azacyclische verbindungen, verfahren zur ihrer herstellung und ihre verwendung als pharmazeutika. |
DE68910999T2 (de) * | 1988-02-19 | 1994-03-24 | Smithkline Beecham Farma | 1,2,3,4-Tetrahydroisoquinoline, Verfharen zu ihrer Herstellung und ihre Verwendung als Kappa-Rezeptor Agonisten. |
JPH02138254A (ja) * | 1988-02-23 | 1990-05-28 | Glaxo Group Ltd | 複素環誘導体 |
KR890012970A (ko) * | 1988-02-23 | 1989-09-20 | 추후보충 | 테트라히드로 이소퀴놀린 유도체 |
PT90001B (pt) * | 1988-03-16 | 1994-06-30 | Zambeletti Spa L | Processo para a preparacao de derivados heterociclicos de etilenodiamina |
GB8824291D0 (en) * | 1988-10-17 | 1988-11-23 | Zambeletti Spa L | Novel use |
GB8824400D0 (en) * | 1988-10-18 | 1988-11-23 | Glaxo Group Ltd | Chemical compounds |
GB8827479D0 (en) * | 1988-11-24 | 1988-12-29 | Zambeletti Spa L | Novel compounds |
GB8830219D0 (en) * | 1988-12-23 | 1989-02-22 | Zambeletti Spa L | Novel compounds |
DE3935371A1 (de) * | 1988-12-23 | 1990-07-05 | Merck Patent Gmbh | Stickstoffhaltige ringverbindungen |
GB8916395D0 (en) * | 1989-07-18 | 1989-09-06 | Zambeletti Spa L | Pharmaceuticals |
GB8926560D0 (en) * | 1989-11-24 | 1990-01-17 | Zambeletti Spa L | Pharmaceuticals |
US5428042A (en) * | 1990-04-28 | 1995-06-27 | Dr Lo Zambeletti S.P.A. | 1-(2H-1-oxo-3,4-dihydronaphtyl-6-yl)-acetyl-piperidines as kappa agonists |
DE4215213A1 (de) * | 1992-05-09 | 1993-11-11 | Merck Patent Gmbh | Arylacetamide |
US5389638A (en) * | 1993-09-10 | 1995-02-14 | Abbott Laboratories | Tetrahydroisoquinolines as alpha-2 antagonists and biogenic amine uptake inhibitors |
TW436484B (en) * | 1996-04-24 | 2001-05-28 | Dev Center Biotechnology | 1,2,3,4-tetrahydroisoquinoline derivatives having a nitrogen-containing heterocyclic methyl substituent, the preparation process and pharmaceutical composition thereof |
RU2441655C2 (ru) * | 2007-03-30 | 2012-02-10 | Тиога Фармасьютикалз Инк. | Агонисты каппа-опиоидов для лечения синдрома раздраженного кишечника с преобладанием диареи и перемежающегося синдрома раздраженного кишечника |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2361390A1 (de) * | 1973-12-10 | 1975-06-19 | Merck Patent Gmbh | Isochinolinderivate und verfahren zu ihrer herstellung |
US4232160A (en) * | 1978-10-18 | 1980-11-04 | Miles Laboratories, Inc. | Isoquinoline propionamides exhibiting analgesic properties |
HU189764B (en) * | 1983-10-25 | 1986-07-28 | Richter Gedeon Vegyeszeti Gyar Rt,Hu | Process for preparing 1-(bis (substituted methyl)-methyl)-isoquinoline-derivatives |
GB8531615D0 (en) * | 1985-12-23 | 1986-02-05 | Zambeletti Spa L | Compounds |
-
1986
- 1986-01-24 GB GB868601796A patent/GB8601796D0/en active Pending
-
1987
- 1987-01-20 DE DE8787300457T patent/DE3772218D1/de not_active Expired - Fee Related
- 1987-01-20 EP EP87300457A patent/EP0232989B1/en not_active Expired - Lifetime
- 1987-01-22 ZA ZA87467A patent/ZA87467B/xx unknown
- 1987-01-22 PT PT84187A patent/PT84187B/pt not_active IP Right Cessation
- 1987-01-22 AU AU67915/87A patent/AU595281B2/en not_active Ceased
- 1987-01-22 DK DK035687A patent/DK35687A/da unknown
- 1987-01-22 US US07/006,068 patent/US4806547A/en not_active Expired - Fee Related
- 1987-01-22 NZ NZ219030A patent/NZ219030A/xx unknown
- 1987-01-23 JP JP62012621A patent/JPH0780855B2/ja not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
DE3772218D1 (de) | 1991-09-26 |
JPS62240665A (ja) | 1987-10-21 |
US4806547A (en) | 1989-02-21 |
AU6791587A (en) | 1987-07-30 |
PT84187A (pt) | 1987-02-01 |
PT84187B (pt) | 1989-09-14 |
EP0232989B1 (en) | 1991-08-21 |
DK35687D0 (da) | 1987-01-22 |
GB8601796D0 (en) | 1986-02-26 |
EP0232989A3 (en) | 1988-06-22 |
NZ219030A (en) | 1990-06-26 |
JPH0780855B2 (ja) | 1995-08-30 |
ZA87467B (en) | 1987-11-25 |
AU595281B2 (en) | 1990-03-29 |
EP0232989A2 (en) | 1987-08-19 |
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