ZA87467B - Isoquinoline derivatives - Google Patents

Isoquinoline derivatives

Info

Publication number
ZA87467B
ZA87467B ZA87467A ZA87467A ZA87467B ZA 87467 B ZA87467 B ZA 87467B ZA 87467 A ZA87467 A ZA 87467A ZA 87467 A ZA87467 A ZA 87467A ZA 87467 B ZA87467 B ZA 87467B
Authority
ZA
South Africa
Prior art keywords
isoquinoline derivatives
isoquinoline
derivatives
Prior art date
Application number
ZA87467A
Other languages
English (en)
Inventor
Giuseppe Giardina
Vittorio Vecchietti
Original Assignee
Zambeletti Spa L
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zambeletti Spa L filed Critical Zambeletti Spa L
Publication of ZA87467B publication Critical patent/ZA87467B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA87467A 1986-01-24 1987-01-22 Isoquinoline derivatives ZA87467B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB868601796A GB8601796D0 (en) 1986-01-24 1986-01-24 Compounds

Publications (1)

Publication Number Publication Date
ZA87467B true ZA87467B (en) 1987-11-25

Family

ID=10591914

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA87467A ZA87467B (en) 1986-01-24 1987-01-22 Isoquinoline derivatives

Country Status (10)

Country Link
US (1) US4806547A (xx)
EP (1) EP0232989B1 (xx)
JP (1) JPH0780855B2 (xx)
AU (1) AU595281B2 (xx)
DE (1) DE3772218D1 (xx)
DK (1) DK35687A (xx)
GB (1) GB8601796D0 (xx)
NZ (1) NZ219030A (xx)
PT (1) PT84187B (xx)
ZA (1) ZA87467B (xx)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3670080D1 (de) * 1985-12-23 1990-05-10 Zambeletti Spa L Azacyclische verbindungen, verfahren zur ihrer herstellung und ihre verwendung als pharmazeutika.
ATE97893T1 (de) * 1988-02-19 1993-12-15 Smithkline Beecham Farma 1,2,3,4-tetrahydroisoquinoline, verfharen zu ihrer herstellung und ihre verwendung als kappa- rezeptor agonisten.
JPH02138254A (ja) * 1988-02-23 1990-05-28 Glaxo Group Ltd 複素環誘導体
KR890012970A (ko) * 1988-02-23 1989-09-20 추후보충 테트라히드로 이소퀴놀린 유도체
DE68923891T2 (de) * 1988-03-16 1996-02-22 Smithkline Beecham Farm Heterocyclische Derivate.
GB8824291D0 (en) * 1988-10-17 1988-11-23 Zambeletti Spa L Novel use
GB8824400D0 (en) * 1988-10-18 1988-11-23 Glaxo Group Ltd Chemical compounds
GB8827479D0 (en) * 1988-11-24 1988-12-29 Zambeletti Spa L Novel compounds
GB8830219D0 (en) * 1988-12-23 1989-02-22 Zambeletti Spa L Novel compounds
DE3935371A1 (de) * 1988-12-23 1990-07-05 Merck Patent Gmbh Stickstoffhaltige ringverbindungen
GB8916395D0 (en) * 1989-07-18 1989-09-06 Zambeletti Spa L Pharmaceuticals
GB8926560D0 (en) * 1989-11-24 1990-01-17 Zambeletti Spa L Pharmaceuticals
WO1991017116A1 (en) * 1990-04-28 1991-11-14 Dr. Lo. Zambeletti S.P.A. Novel 1-(2h-1-oxo-3,4-dihydronaphtyl-6)-acetyl-piperidines, process for their preparation and therapeutic use
DE4215213A1 (de) * 1992-05-09 1993-11-11 Merck Patent Gmbh Arylacetamide
US5389638A (en) * 1993-09-10 1995-02-14 Abbott Laboratories Tetrahydroisoquinolines as alpha-2 antagonists and biogenic amine uptake inhibitors
TW436484B (en) * 1996-04-24 2001-05-28 Dev Center Biotechnology 1,2,3,4-tetrahydroisoquinoline derivatives having a nitrogen-containing heterocyclic methyl substituent, the preparation process and pharmaceutical composition thereof
EP2136801B1 (en) * 2007-03-30 2012-08-29 Tioga Pharmaceuticals, Inc. Kappa-opiate agonists for the treatment of diarrhea-predominant and alternating irritable bowel syndrome

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2361390A1 (de) * 1973-12-10 1975-06-19 Merck Patent Gmbh Isochinolinderivate und verfahren zu ihrer herstellung
US4232160A (en) * 1978-10-18 1980-11-04 Miles Laboratories, Inc. Isoquinoline propionamides exhibiting analgesic properties
HU189764B (en) * 1983-10-25 1986-07-28 Richter Gedeon Vegyeszeti Gyar Rt,Hu Process for preparing 1-(bis (substituted methyl)-methyl)-isoquinoline-derivatives
GB8531615D0 (en) * 1985-12-23 1986-02-05 Zambeletti Spa L Compounds

Also Published As

Publication number Publication date
GB8601796D0 (en) 1986-02-26
PT84187A (pt) 1987-02-01
DE3772218D1 (de) 1991-09-26
EP0232989A2 (en) 1987-08-19
DK35687A (da) 1987-07-25
DK35687D0 (da) 1987-01-22
JPS62240665A (ja) 1987-10-21
US4806547A (en) 1989-02-21
EP0232989B1 (en) 1991-08-21
EP0232989A3 (en) 1988-06-22
JPH0780855B2 (ja) 1995-08-30
AU595281B2 (en) 1990-03-29
NZ219030A (en) 1990-06-26
PT84187B (pt) 1989-09-14
AU6791587A (en) 1987-07-30

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