DE3670080D1 - Azacyclische verbindungen, verfahren zur ihrer herstellung und ihre verwendung als pharmazeutika. - Google Patents

Azacyclische verbindungen, verfahren zur ihrer herstellung und ihre verwendung als pharmazeutika.

Info

Publication number
DE3670080D1
DE3670080D1 DE8686309874T DE3670080T DE3670080D1 DE 3670080 D1 DE3670080 D1 DE 3670080D1 DE 8686309874 T DE8686309874 T DE 8686309874T DE 3670080 T DE3670080 T DE 3670080T DE 3670080 D1 DE3670080 D1 DE 3670080D1
Authority
DE
Germany
Prior art keywords
pharmaceutical
production
azacyclic compounds
azacyclic
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8686309874T
Other languages
English (en)
Inventor
Vittorio Dr Lo Zamb Vecchietti
Massimo Dr Lo Zambel Signorini
Antonio Dr Lo Zambele Giordani
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dr L Zambeletti SpA
Original Assignee
Dr L Zambeletti SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB858531617A external-priority patent/GB8531617D0/en
Priority claimed from GB868621136A external-priority patent/GB8621136D0/en
Application filed by Dr L Zambeletti SpA filed Critical Dr L Zambeletti SpA
Application granted granted Critical
Publication of DE3670080D1 publication Critical patent/DE3670080D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/02—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D223/04—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with only hydrogen atoms, halogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • C07D207/09—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE8686309874T 1985-12-23 1986-12-17 Azacyclische verbindungen, verfahren zur ihrer herstellung und ihre verwendung als pharmazeutika. Expired - Fee Related DE3670080D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB858531617A GB8531617D0 (en) 1985-12-23 1985-12-23 Compounds
GB868621136A GB8621136D0 (en) 1986-09-02 1986-09-02 Compounds

Publications (1)

Publication Number Publication Date
DE3670080D1 true DE3670080D1 (de) 1990-05-10

Family

ID=26290150

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8686309874T Expired - Fee Related DE3670080D1 (de) 1985-12-23 1986-12-17 Azacyclische verbindungen, verfahren zur ihrer herstellung und ihre verwendung als pharmazeutika.

Country Status (9)

Country Link
US (2) US4801585A (de)
EP (1) EP0232612B1 (de)
AU (1) AU591210B2 (de)
DE (1) DE3670080D1 (de)
DK (1) DK625086A (de)
ES (1) ES2017932B3 (de)
GR (1) GR3000472T3 (de)
NZ (1) NZ218749A (de)
PT (1) PT83998B (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2017932B3 (es) * 1985-12-23 1991-03-16 Dr Lo Zambeletti S P A Compuestos azaciclicos, procedimientos de su preparacion y su uso como farmacos.
EP0260041B1 (de) * 1986-09-02 1991-01-30 Dr. Lo. Zambeletti S.p.A. 1-Acylsubstituierte Piperidinderivate
EP0261842B1 (de) * 1986-09-17 1990-11-22 Dr. Lo. Zambeletti S.p.A. N-1-acylierte-[1-(phenyl- oder benzyl-)]-1,2-Äthylendiamine
KR890005052A (ko) * 1986-12-22 1989-05-11 기오르지오 스키니나 신규 피페리딘 유도체
GB8803259D0 (en) * 1988-02-12 1988-03-09 Zambeletti Spa L Compounds
EP0330467A1 (de) * 1988-02-23 1989-08-30 Glaxo Group Limited Heterocyclische Verbindungen
GB8804104D0 (en) * 1988-02-23 1988-03-23 Glaxo Group Ltd Chemical compounds
US5512567A (en) * 1988-08-24 1996-04-30 Sankyo Company, Limited Analgesic compounds, their preparation, and pharmaceutical compositions containing them
US5021413B1 (en) * 1988-08-24 1994-12-13 Sankyo Co Analgesic thiomorpholins, their preparation, and pharmaceutical compositions containing them
US5270327A (en) * 1988-08-24 1993-12-14 Sankyo Company, Limited Analgesic compounds, their preparation, and pharmaceutical compositions containing them
EP0361791B1 (de) * 1988-09-26 1995-11-08 Smithkline Beecham Farmaceutici S.p.A. Azacyclische Verbindungen, verwendbar als Arzneimittel
US5001142A (en) * 1989-07-19 1991-03-19 American Cyanamid Company 1-substituted-2-(3-amino-1-propynyl)pyrrolidine derivatives
GB8926560D0 (en) * 1989-11-24 1990-01-17 Zambeletti Spa L Pharmaceuticals
EP0447704A1 (de) * 1990-03-21 1991-09-25 Smithkline Beecham Farmaceutici S.p.A. N-Acylierte azyklische Verbindungen, Verfahren zu ihrer Herstellung und ihre Anwendung als Arzneimittel
CA2081351A1 (en) * 1990-04-28 1991-10-29 Vittorio Vecchietti 1-(2h-1-oxo-3, 4-dihydronaphtyl-6) -acetyl-piperidines, process for their preparation and therapeutic use
US5346908A (en) * 1992-06-25 1994-09-13 National Institutes Of Health Nitrogen-containing cyclohetero cycloheteroaminoaryl derivatives for CNS disorders
PT650476E (pt) * 1993-04-07 2002-11-29 Otsuka Pharma Co Ltd Agente vasodilatador periferico que contem derivados n-acilados de 4-amino-piperidina como ingredientes activos
CN100398154C (zh) * 2001-03-30 2008-07-02 东丽株式会社 精神神经疾病治疗药
MY142362A (en) * 2004-01-29 2010-11-30 Otsuka Pharma Co Ltd Pharmaceutical composition for promoting angiogenesis

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2684965A (en) * 1950-08-10 1954-07-27 Abbott Lab Aminoalkylpiperidines
GB1077173A (en) * 1965-03-19 1967-07-26 American Cyanamid Co Substituted alkylene piperidines and methods of preparation thereof
GB1250719A (de) * 1969-03-19 1971-10-20
FR2314179A1 (fr) * 1975-06-12 1977-01-07 Ile De France Nouvelles enamines et leur procede de preparation
US4145435A (en) * 1976-11-12 1979-03-20 The Upjohn Company 2-aminocycloaliphatic amide compounds
EP0052311A1 (de) * 1980-11-19 1982-05-26 Sterling Drug Inc. 1-(Benzoylphenyl-niederalkyl)-piperidine und entsprechende Carbinole und ihre Herstellung
US4339576A (en) * 1980-11-19 1982-07-13 Sterling Drug Inc. Anti-asthmatic, anti-allergic, anti-cholinergic, bronchodilator and anti-inflammatory 1-[(benzoylphenyl)-lower-alkyl]piperidines and analogs thereof
US4588585A (en) * 1982-10-19 1986-05-13 Cetus Corporation Human recombinant cysteine depleted interferon-β muteins
AT376669B (de) * 1982-11-26 1984-12-27 Laevosan Gmbh & Co Kg Verfahren zur herstellung neuer thienylessigsaeureamid-derivate und pharmazeutisch vertraeglicher saeureadditionssalze davon
DE3329621A1 (de) * 1983-08-17 1985-02-28 Bayer Ag, 5090 Leverkusen Aminoalkyl-imidazothiadiazol-alkencarbonsaeureamide, neue zwischenprodukte zu ihrer herstellung, ihre herstellung und ihre verwendung in arzneimitteln
US4598087A (en) * 1983-12-06 1986-07-01 Warner-Lambert Company Substituted trans-1,2-diaminocyclohexyl amide compounds
GB8531615D0 (en) * 1985-12-23 1986-02-05 Zambeletti Spa L Compounds
ES2017932B3 (es) * 1985-12-23 1991-03-16 Dr Lo Zambeletti S P A Compuestos azaciclicos, procedimientos de su preparacion y su uso como farmacos.
GB8601796D0 (en) * 1986-01-24 1986-02-26 Zambeletti Spa L Compounds
EP0260041B1 (de) * 1986-09-02 1991-01-30 Dr. Lo. Zambeletti S.p.A. 1-Acylsubstituierte Piperidinderivate
KR890005052A (ko) * 1986-12-22 1989-05-11 기오르지오 스키니나 신규 피페리딘 유도체
GB8803259D0 (en) * 1988-02-12 1988-03-09 Zambeletti Spa L Compounds

Also Published As

Publication number Publication date
GR3000472T3 (en) 1991-06-28
AU6682486A (en) 1987-06-25
DK625086A (da) 1987-06-24
PT83998A (en) 1987-01-01
DK625086D0 (da) 1986-12-22
EP0232612B1 (de) 1990-04-04
US4801585A (en) 1989-01-31
PT83998B (pt) 1989-05-31
USRE33906E (en) 1992-04-28
ES2017932B3 (es) 1991-03-16
EP0232612A1 (de) 1987-08-19
AU591210B2 (en) 1989-11-30
NZ218749A (en) 1990-06-26

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee