DK3518933T4 - Fremgangsmåder til behandling af uterusfibromer og endometriose - Google Patents

Fremgangsmåder til behandling af uterusfibromer og endometriose Download PDF

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Publication number
DK3518933T4
DK3518933T4 DK17823018.1T DK17823018T DK3518933T4 DK 3518933 T4 DK3518933 T4 DK 3518933T4 DK 17823018 T DK17823018 T DK 17823018T DK 3518933 T4 DK3518933 T4 DK 3518933T4
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DK
Denmark
Prior art keywords
endometriosis
methods
treating uterine
uterine fibromas
fibromas
Prior art date
Application number
DK17823018.1T
Other languages
Danish (da)
English (en)
Other versions
DK3518933T3 (da
Inventor
Jr Paul N Mudd
Susan Wollowitz
Mark Hibberd
Vijaykumar Reddy Rajasekhar
Lynn Seely
Mayukh Vasant Sukhatme
Masataka Tanimoto
Brendan Mark Johnson
Original Assignee
Takeda Pharmaceuticals Co
Sumitomo Pharma Switzerland Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=60915460&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK3518933(T4) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Takeda Pharmaceuticals Co, Sumitomo Pharma Switzerland Gmbh filed Critical Takeda Pharmaceuticals Co
Publication of DK3518933T3 publication Critical patent/DK3518933T3/da
Application granted granted Critical
Publication of DK3518933T4 publication Critical patent/DK3518933T4/da

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Surgical Instruments (AREA)
DK17823018.1T 2016-09-30 2017-09-29 Fremgangsmåder til behandling af uterusfibromer og endometriose DK3518933T4 (da)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201662402055P 2016-09-30 2016-09-30
US201662402150P 2016-09-30 2016-09-30
US201662402034P 2016-09-30 2016-09-30
US201762492839P 2017-05-01 2017-05-01
US201762528409P 2017-07-03 2017-07-03
PCT/EP2017/074907 WO2018060501A2 (en) 2016-09-30 2017-09-29 Methods of treating uterine fibroids and endometriosis

Publications (2)

Publication Number Publication Date
DK3518933T3 DK3518933T3 (da) 2022-05-30
DK3518933T4 true DK3518933T4 (da) 2025-04-22

Family

ID=60915460

Family Applications (1)

Application Number Title Priority Date Filing Date
DK17823018.1T DK3518933T4 (da) 2016-09-30 2017-09-29 Fremgangsmåder til behandling af uterusfibromer og endometriose

Country Status (24)

Country Link
US (4) US11033551B2 (enExample)
EP (2) EP4094766B1 (enExample)
JP (1) JP7043503B2 (enExample)
CN (1) CN110312512B (enExample)
AU (2) AU2017336363B2 (enExample)
BR (1) BR112019006227A2 (enExample)
CA (1) CA3038879A1 (enExample)
CY (1) CY1125254T1 (enExample)
DK (1) DK3518933T4 (enExample)
ES (2) ES2912929T5 (enExample)
FI (1) FI3518933T4 (enExample)
HR (1) HRP20220708T4 (enExample)
HU (2) HUE072130T2 (enExample)
IL (2) IL300580B2 (enExample)
LT (1) LT3518933T (enExample)
MD (1) MD3518933T4 (enExample)
MX (1) MX2019003726A (enExample)
NZ (1) NZ752916A (enExample)
PL (2) PL3518933T5 (enExample)
PT (1) PT3518933T (enExample)
RS (1) RS63300B2 (enExample)
SI (1) SI3518933T2 (enExample)
SM (1) SMT202200254T1 (enExample)
WO (1) WO2018060501A2 (enExample)

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WO2018060501A2 (en) 2016-09-30 2018-04-05 Myovant Sciences Gmbh Methods of treating uterine fibroids and endometriosis
EP3518932B1 (en) 2016-09-30 2024-11-13 Sumitomo Pharma Switzerland GmbH Treatment of prostate cancer
ES3018358T3 (es) 2017-06-05 2025-05-16 Kissei Pharmaceutical Régimen de dosificación que comprende un antagonista de la hormona liberadora de gonadotropina para tratar fibromas uterinos y reducir la pérdida de sangre menstrual
US11980621B2 (en) 2017-06-05 2024-05-14 Kissei Pharmaceutical Co., Ltd. Gonadotropin-releasing hormone antagonist dosing regimens for the treatment of endometriosis
AU2018419533A1 (en) * 2018-04-19 2020-11-12 Abbvie Inc. Methods of treating heavy menstrual bleeding
MA54058A (fr) * 2018-10-29 2021-09-08 ObsEva SA Compositions et méthodes de traitement de l'endométriose interne et de l'endométriose rectovaginale
RU2711658C1 (ru) * 2019-04-16 2020-01-20 Федеральное государственное бюджетное научное учреждение "Научно-исследовательский институт акушерства, гинекологии и репродуктологии имени Д.О. Отта" Способ лечения наружного генитального эндометриоза
CN110194776B (zh) * 2019-06-27 2021-05-28 四川伊诺达博医药科技有限公司 一种瑞卢戈利的合成方法
JP2022543308A (ja) * 2019-08-08 2022-10-11 オブセヴァ エス.エー. エストロゲン依存性障害の治療のための組成物及び方法
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EP4041738A1 (en) * 2019-10-10 2022-08-17 Myovant Sciences GmbH Crystalline solvated forms of n-(4-(1-(2,6-difluorobenzyl)-5- ((dimethylamino)methyl)-3-(6-methoxy-3-pyridazinyl)-2,4-dioxo-1,2,3,4- tetrahydrothieno[2,3-d]pyrimidin-6-yl)phenyl)-n'-methoxyurea
IL295781A (en) * 2020-02-19 2022-10-01 Aspira Women’S Health Inc Preparations with improved specificity for the evaluation of endometriosis
CN113384581B (zh) * 2020-03-12 2023-11-14 成都倍特药业股份有限公司 一种包含促性腺激素释放激素拮抗剂的药物组合物
AU2021278303A1 (en) * 2020-05-29 2023-02-09 Sumitomo Pharma Switzerland Gmbh Combination solid oral dosage forms of gonadotropin-releasing hormone antagonists
EP4243829A1 (en) 2020-11-11 2023-09-20 Myovant Sciences GmbH Methods of administering relugolix
WO2023066941A1 (en) 2021-10-18 2023-04-27 Myovant Sciences Gmbh Crystalline form of an ethanol solvate of n-(4-(1-(2,6-difluorobenzyl)-5-((dimethylamino)methyl)-3-(6-methoxy-3-pyridazinyl)-2,4-dioxo-1,2,3,4-tetrahydrothieno[2,3-d]pyrimidin-6-yl)phenyl)-n'-methoxyurea
CN117069735A (zh) * 2022-05-10 2023-11-17 北京海美源医药科技有限公司 一种高效合成瑞卢戈利的方法和其应用
WO2024015934A2 (en) * 2022-07-13 2024-01-18 Arizona Board Of Regents On Behalf Of The University Of Arizona Methods of diagnostic screening and early detection of adenomyosis
WO2024102620A2 (en) * 2022-11-09 2024-05-16 Tempest Therapeutics, Inc. Triazolone compounds and uses thereof
WO2025106820A1 (en) * 2023-11-16 2025-05-22 University Of South Florida Method of preventing progesterone contraceptive-induced abnormal uterine bleeding (aub)

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CN115279769A (zh) 2019-10-10 2022-11-01 梦欧文科学有限责任公司 N-(4-(1-(2,6-二氟苄基)-5-((二甲基氨基)甲基)-3-(6-甲氧基-3-哒嗪基)-2,4-二氧代-1,2,3,4-四氢噻吩并[2,3-d]嘧啶-6-基)苯基)-n’-甲氧基脲的结晶形式
EP4041738A1 (en) 2019-10-10 2022-08-17 Myovant Sciences GmbH Crystalline solvated forms of n-(4-(1-(2,6-difluorobenzyl)-5- ((dimethylamino)methyl)-3-(6-methoxy-3-pyridazinyl)-2,4-dioxo-1,2,3,4- tetrahydrothieno[2,3-d]pyrimidin-6-yl)phenyl)-n'-methoxyurea
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WO2023066941A1 (en) 2021-10-18 2023-04-27 Myovant Sciences Gmbh Crystalline form of an ethanol solvate of n-(4-(1-(2,6-difluorobenzyl)-5-((dimethylamino)methyl)-3-(6-methoxy-3-pyridazinyl)-2,4-dioxo-1,2,3,4-tetrahydrothieno[2,3-d]pyrimidin-6-yl)phenyl)-n'-methoxyurea

Also Published As

Publication number Publication date
FI3518933T4 (fi) 2025-05-14
CN110312512A (zh) 2019-10-08
AU2022241582B2 (en) 2024-06-13
ES2912929T5 (en) 2025-05-09
ES3018413T3 (es) 2025-05-16
PL3518933T5 (pl) 2025-05-05
RS63300B2 (sr) 2025-05-30
DK3518933T3 (da) 2022-05-30
EP3518933A2 (en) 2019-08-07
JP2019529575A (ja) 2019-10-17
HUE059101T2 (hu) 2022-10-28
NZ752916A (en) 2022-09-30
CA3038879A1 (en) 2018-04-05
US20220370462A1 (en) 2022-11-24
EP3518933B1 (en) 2022-03-16
AU2017336363B2 (en) 2022-08-04
SI3518933T1 (sl) 2022-06-30
US20240165118A1 (en) 2024-05-23
BR112019006227A2 (pt) 2019-06-18
IL300580B1 (en) 2025-07-01
US20190262346A1 (en) 2019-08-29
CN110312512B (zh) 2023-05-09
PL4094766T3 (pl) 2025-07-28
MX2019003726A (es) 2019-09-26
AU2022241582A1 (en) 2022-10-27
HRP20220708T1 (hr) 2022-07-22
IL265700B2 (en) 2023-07-01
HUE072130T2 (hu) 2025-10-28
RS63300B1 (sr) 2022-07-29
SI3518933T2 (sl) 2025-05-30
IL265700B1 (en) 2023-03-01
MD3518933T2 (ro) 2022-07-31
AU2017336363A1 (en) 2019-05-16
SMT202200254T1 (it) 2022-07-21
EP4094766A1 (en) 2022-11-30
EP3518933B2 (en) 2025-02-26
IL300580B2 (en) 2025-11-01
PL3518933T3 (pl) 2022-06-20
JP7043503B2 (ja) 2022-03-29
US11957684B2 (en) 2024-04-16
US11793812B2 (en) 2023-10-24
AU2022241582C1 (en) 2024-11-28
US20210401841A1 (en) 2021-12-30
IL265700A (en) 2019-05-30
CY1125254T1 (el) 2024-02-16
EP4094766B1 (en) 2025-04-02
PT3518933T (pt) 2022-05-10
WO2018060501A3 (en) 2018-05-11
LT3518933T (lt) 2022-06-10
US11033551B2 (en) 2021-06-15
IL300580A (en) 2023-04-01
HRP20220708T4 (hr) 2025-04-25
ES2912929T3 (es) 2022-05-30
WO2018060501A2 (en) 2018-04-05
MD3518933T4 (ro) 2025-10-31

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