DK3518932T3 - Behandling af prostatacancer - Google Patents

Behandling af prostatacancer Download PDF

Info

Publication number
DK3518932T3
DK3518932T3 DK17823017.3T DK17823017T DK3518932T3 DK 3518932 T3 DK3518932 T3 DK 3518932T3 DK 17823017 T DK17823017 T DK 17823017T DK 3518932 T3 DK3518932 T3 DK 3518932T3
Authority
DK
Denmark
Prior art keywords
prostate cancer
cancer treatment
treatment
prostate
cancer
Prior art date
Application number
DK17823017.3T
Other languages
Danish (da)
English (en)
Inventor
Brendan Mark Johnson
Lynn Seely
Vijaykumar Reddy Rajasekhar
David B Maclean
Hélène M Faessel
Paul N Mudd
Original Assignee
Takeda Pharmaceuticals Co
Sumitomo Pharma Switzerland Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=60915459&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK3518932(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Takeda Pharmaceuticals Co, Sumitomo Pharma Switzerland Gmbh filed Critical Takeda Pharmaceuticals Co
Application granted granted Critical
Publication of DK3518932T3 publication Critical patent/DK3518932T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50Pyridazines; Hydrogenated pyridazines
    • A61K31/501Pyridazines; Hydrogenated pyridazines not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • A61K31/41661,3-Diazoles having oxo groups directly attached to the heterocyclic ring, e.g. phenytoin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK17823017.3T 2016-09-30 2017-09-29 Behandling af prostatacancer DK3518932T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662402150P 2016-09-30 2016-09-30
US201662402004P 2016-09-30 2016-09-30
PCT/EP2017/074849 WO2018060463A2 (en) 2016-09-30 2017-09-29 Treatment of prostate cancer

Publications (1)

Publication Number Publication Date
DK3518932T3 true DK3518932T3 (da) 2025-01-27

Family

ID=60915459

Family Applications (1)

Application Number Title Priority Date Filing Date
DK17823017.3T DK3518932T3 (da) 2016-09-30 2017-09-29 Behandling af prostatacancer

Country Status (21)

Country Link
US (8) US10449191B2 (cg-RX-API-DMAC7.html)
EP (2) EP4520398A3 (cg-RX-API-DMAC7.html)
JP (1) JP7062673B2 (cg-RX-API-DMAC7.html)
CN (1) CN110248661A (cg-RX-API-DMAC7.html)
AU (2) AU2017334035B2 (cg-RX-API-DMAC7.html)
BR (1) BR112019006228A2 (cg-RX-API-DMAC7.html)
CA (1) CA3038875A1 (cg-RX-API-DMAC7.html)
DK (1) DK3518932T3 (cg-RX-API-DMAC7.html)
ES (1) ES3002857T3 (cg-RX-API-DMAC7.html)
FI (1) FI3518932T3 (cg-RX-API-DMAC7.html)
HR (1) HRP20241740T1 (cg-RX-API-DMAC7.html)
HU (1) HUE070578T2 (cg-RX-API-DMAC7.html)
IL (3) IL308528A (cg-RX-API-DMAC7.html)
LT (1) LT3518932T (cg-RX-API-DMAC7.html)
MA (1) MA46361A (cg-RX-API-DMAC7.html)
MX (2) MX2019003733A (cg-RX-API-DMAC7.html)
NZ (1) NZ752918A (cg-RX-API-DMAC7.html)
PL (1) PL3518932T3 (cg-RX-API-DMAC7.html)
PT (1) PT3518932T (cg-RX-API-DMAC7.html)
SI (1) SI3518932T1 (cg-RX-API-DMAC7.html)
WO (1) WO2018060463A2 (cg-RX-API-DMAC7.html)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LT3415517T (lt) 2012-09-28 2022-06-10 Takeda Pharmaceutical Company Limited Kristalinė 1-(4-(1-(2,6-difluorbenzil)-5-dimetilaminometil-3-(6-metoksipiridazin-3-il)-2,4-diokso-1,2,3,4- tetrahidrotieno(2,3-d)pirimidin-6-il)fenil)-3-metoksikarbamido forma
FI3518932T3 (fi) 2016-09-30 2025-02-03 Sumitomo Pharma Switzerland Gmbh Eturauhassyövän hoito
DK3518933T4 (da) 2016-09-30 2025-04-22 Takeda Pharmaceuticals Co Fremgangsmåder til behandling af uterusfibromer og endometriose
CN110194776B (zh) * 2019-06-27 2021-05-28 四川伊诺达博医药科技有限公司 一种瑞卢戈利的合成方法
CN115175912B (zh) * 2019-10-10 2025-04-11 住友制药瑞士有限公司 N-(4-(1-(2,6-二氟苄基)-5-((二甲基氨基)甲基)-3-(6-甲氧基-3-哒嗪基)-2,4-二氧代-1,2,3,4-四氢噻吩并[2,3-d]嘧啶-6-基)苯基)-n′-甲氧基脲的结晶溶剂化形式
CN115279769A (zh) * 2019-10-10 2022-11-01 梦欧文科学有限责任公司 N-(4-(1-(2,6-二氟苄基)-5-((二甲基氨基)甲基)-3-(6-甲氧基-3-哒嗪基)-2,4-二氧代-1,2,3,4-四氢噻吩并[2,3-d]嘧啶-6-基)苯基)-n’-甲氧基脲的结晶形式
BR112022023937A2 (pt) 2020-05-29 2022-12-27 Myovant Sciences Gmbh Formas de dosagem oral sólidas de combinação de antagonistas do hormônio liberador de gonadotropina
US20230384316A1 (en) * 2020-10-20 2023-11-30 Baylor College Of Medicine Multiplex metabolic markers in plasma for early detection of african american prostate cancer
WO2022101303A1 (en) 2020-11-11 2022-05-19 Myovant Sciences Gmbh Methods of administering relugolix
JP2024540922A (ja) 2021-10-18 2024-11-06 スミトモ ファーマ スウィッツァーランド ゲーエムベーハー N-(4-(1-(2,6-ジフルオロベンジル)-5-((ジメチルアミノ)メチル)-3-(6-メトキシ-3-ピリダジニル)-2,4-ジオキソ-1,2,3,4-テトラヒドロチエノ[2,3-d]ピリミジン-6-イル)フェニル)-N’-メトキシ尿素のエタノール溶媒和物の結晶形
WO2023152611A1 (en) * 2022-02-11 2023-08-17 Aragon Pharmaceuticals, Inc. Apalutamide and relugolix for the treatment of prostate cancer

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2710637B1 (fr) 1993-09-28 1995-12-08 Roquette Freres Mannitol pulvérulent de friabilité modérée et son procédé de préparation.
TWI225863B (en) 1999-03-24 2005-01-01 Takeda Chemical Industries Ltd Thienopyrimidine compounds, their production and use
US6297379B1 (en) 1999-03-24 2001-10-02 Takeda Chemical Industries, Ltd. Thienopyrimidine compounds, their production and use
CN1539836A (zh) 2000-02-29 2004-10-27 武田药品工业株式会社 制备噻吩并嘧啶衍生物的方法
WO2003057689A1 (en) 2002-01-02 2003-07-17 Fujisawa Pharmaceutical Co., Ltd. Aminopyrimidine compounds, processes for their preparation and pharmaceutical compositions containing them
EP1479684A4 (en) 2002-01-30 2006-01-04 Takeda Pharmaceutical THIENOPYRIMIDINES, METHODS OF MAKING AND USING SAME
EP1480679B1 (en) 2002-02-26 2007-05-23 Astrazeneca AB Pharmaceutical formulation of iressa comprising a water-soluble cellulose derivative
EP1591446B1 (en) 2003-01-29 2013-03-06 Takeda Pharmaceutical Company Limited Thienopyrimidine compounds and use thereof
ATE407679T1 (de) 2003-07-07 2008-09-15 Neurocrine Biosciences Inc Pyrimidin-2,4-dion-derivate als gonadotropin freisetzende hormon-rezeptor-antagonisten
JPWO2007011072A1 (ja) 2005-07-22 2009-02-05 武田薬品工業株式会社 早発排卵の防止剤
KR101506750B1 (ko) 2007-04-06 2015-03-27 뉴로크린 바이오사이언시즈 인코퍼레이티드 고나도트로핀-방출 호르몬 수용체 길항제 및 그와 관련된 방법
US8765948B2 (en) 2007-11-07 2014-07-01 Neurocrine Biosciences, Inc. Processes for the preparation of uracil derivatives
TWI539959B (zh) 2008-02-11 2016-07-01 菲瑞茵國際中心股份有限公司 治療轉移階段攝護腺癌的方法
WO2010026993A1 (ja) 2008-09-03 2010-03-11 武田薬品工業株式会社 製剤における吸収性改善方法および吸収性が改善された製剤
LT3415517T (lt) 2012-09-28 2022-06-10 Takeda Pharmaceutical Company Limited Kristalinė 1-(4-(1-(2,6-difluorbenzil)-5-dimetilaminometil-3-(6-metoksipiridazin-3-il)-2,4-diokso-1,2,3,4- tetrahidrotieno(2,3-d)pirimidin-6-il)fenil)-3-metoksikarbamido forma
US10821152B2 (en) 2014-08-26 2020-11-03 Betanien Hospital Methods, agents and compositions for treatment of inflammatory conditions
RS64377B1 (sr) 2015-02-26 2023-08-31 Takeda Pharmaceuticals Co Tableta koja sadrži derivat metoksiuree i čestice manitola
WO2017040841A1 (en) 2015-09-01 2017-03-09 Abbvie Inc. Methods of administering elagolix
US20180044977A1 (en) 2016-08-12 2018-02-15 Raynor Mfg. Co. Rolling door construction for controlling air leakage
DK3518933T4 (da) 2016-09-30 2025-04-22 Takeda Pharmaceuticals Co Fremgangsmåder til behandling af uterusfibromer og endometriose
FI3518932T3 (fi) 2016-09-30 2025-02-03 Sumitomo Pharma Switzerland Gmbh Eturauhassyövän hoito

Also Published As

Publication number Publication date
IL300071A (en) 2023-03-01
CN110248661A (zh) 2019-09-17
US20200129507A1 (en) 2020-04-30
JP7062673B2 (ja) 2022-05-06
JP2019529574A (ja) 2019-10-17
AU2017334035B2 (en) 2022-11-24
IL308528A (en) 2024-01-01
FI3518932T3 (fi) 2025-02-03
PT3518932T (pt) 2025-01-16
HRP20241740T1 (hr) 2025-02-28
SI3518932T1 (sl) 2025-03-31
ES3002857T3 (en) 2025-03-07
US12336990B2 (en) 2025-06-24
US12144809B1 (en) 2024-11-19
US20250332166A1 (en) 2025-10-30
IL265697B1 (en) 2023-03-01
AU2017334035A1 (en) 2019-05-16
LT3518932T (lt) 2025-02-10
EP3518932A2 (en) 2019-08-07
EP4520398A2 (en) 2025-03-12
US20210205303A1 (en) 2021-07-08
PL3518932T3 (pl) 2025-04-07
IL265697A (en) 2019-05-30
MA46361A (fr) 2021-03-31
US20220401443A1 (en) 2022-12-22
BR112019006228A2 (pt) 2019-06-18
US11583526B2 (en) 2023-02-21
EP4520398A3 (en) 2025-04-02
CA3038875A1 (en) 2018-04-05
AU2023201047A1 (en) 2023-03-23
NZ752918A (en) 2022-09-30
US10449191B2 (en) 2019-10-22
WO2018060463A3 (en) 2018-05-11
EP3518932B1 (en) 2024-11-13
HUE070578T2 (hu) 2025-06-28
US12097198B2 (en) 2024-09-24
WO2018060463A2 (en) 2018-04-05
US20190224196A1 (en) 2019-07-25
AU2023201047B2 (en) 2025-04-03
US20250082632A1 (en) 2025-03-13
US20240358700A1 (en) 2024-10-31
US10786501B2 (en) 2020-09-29
MX2023001468A (es) 2023-03-03
US20250057839A1 (en) 2025-02-20
IL265697B2 (en) 2023-07-01
MX2019003733A (es) 2019-09-26

Similar Documents

Publication Publication Date Title
IL296080B1 (en) Method for treating cancer
IL269026A (en) Methods of treating tumor
IL255261A0 (en) Methods for treating cancer
EP3651772A4 (en) ANTI-CANCER POLYTHERAPY
DK3288581T3 (da) Fremgangsmåde til behandling af cancer
SI3283527T1 (sl) Kombinirana terapija proti raku
DK3518932T3 (da) Behandling af prostatacancer
EP3474854A4 (en) DRUG ASSOCIATIONS FOR THE TREATMENT OF CANCER
DK3580211T3 (da) 2-heteroaryl-3-oxo-2,3-dihydropyridazin-4-carboxamider til behandling af cancer
IL264443A (en) Methods of treating prostate cancer
IL284875A (en) Lasofoxifene treatment of breast cancer
DK3076976T3 (da) Fremgangsmåder til behandling af cancer
DK3458052T3 (da) Kombinationsbehandling af cancer
IL268463A (en) Cancer treatment
EP3546020A4 (en) CANCER TREATMENT APPARATUS
EP3413927A4 (en) CANCER THERAPY
DK3303616T3 (da) Fremgangsmåder til prognose af prostatakræft
DK3353177T3 (da) Tricykliske heterocykler til behandling af cancer
EP3593139C0 (en) CANCER BIOMARKERS
EP3576791A4 (en) CALRETICULIN-MEDIATION CANCER TREATMENT
HUE040167T2 (hu) Rákkezelés
IL264589A (en) Combination therapy for the treatment of pancreatic cancer
DK3532076T3 (da) Immunterapeutiske behandlinger af tumorer
IL308399A (en) Methods of treating cancer
IL281600A (en) Methods of treating cancer