DK3506882T3 - Fremstilling af størrelseskontrollerede mikropartikler - Google Patents
Fremstilling af størrelseskontrollerede mikropartikler Download PDFInfo
- Publication number
- DK3506882T3 DK3506882T3 DK17758869.6T DK17758869T DK3506882T3 DK 3506882 T3 DK3506882 T3 DK 3506882T3 DK 17758869 T DK17758869 T DK 17758869T DK 3506882 T3 DK3506882 T3 DK 3506882T3
- Authority
- DK
- Denmark
- Prior art keywords
- manufacture
- size
- controlled microparticles
- microparticles
- controlled
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title 1
- 239000011859 microparticle Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
- A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
- A61K49/223—Microbubbles, hollow microspheres, free gas bubbles, gas microspheres
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
- A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
- A61K49/226—Solutes, emulsions, suspensions, dispersions, semi-solid forms, e.g. hydrogels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5089—Processes
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Dispersion Chemistry (AREA)
- Physics & Mathematics (AREA)
- Acoustics & Sound (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16186356 | 2016-08-30 | ||
| PCT/EP2017/071788 WO2018041906A1 (en) | 2016-08-30 | 2017-08-30 | Preparation of size-controlled microparticles |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3506882T3 true DK3506882T3 (da) | 2022-03-21 |
Family
ID=56842765
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK17758869.6T DK3506882T3 (da) | 2016-08-30 | 2017-08-30 | Fremstilling af størrelseskontrollerede mikropartikler |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US10918605B2 (da) |
| EP (1) | EP3506882B1 (da) |
| JP (1) | JP7197465B2 (da) |
| KR (1) | KR102474554B1 (da) |
| CN (1) | CN109640951B (da) |
| AU (1) | AU2017317646B2 (da) |
| CA (1) | CA3032062A1 (da) |
| DK (1) | DK3506882T3 (da) |
| ES (1) | ES2908708T3 (da) |
| IL (1) | IL265070B (da) |
| WO (1) | WO2018041906A1 (da) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107999155A (zh) * | 2017-12-25 | 2018-05-08 | 四川蓝光英诺生物科技股份有限公司 | 微流控芯片及其控制方法、液滴生成装置和微球制备装置 |
| KR20210003737A (ko) | 2018-03-07 | 2021-01-12 | 브라코 스위스 에스.에이. | 크기-제어 미세소포의 제조 |
| KR102180629B1 (ko) * | 2018-12-24 | 2020-11-20 | 서강대학교 산학협력단 | 세포외 소포 기반의 초음파 조영제용 마이크로버블 및 이의 제조방법 |
| KR102044676B1 (ko) * | 2019-03-27 | 2019-11-14 | 주식회사 씨트리 | 생체적합성 고분자 기반 아픽사반 함유 미립구의 제조방법 |
| EP3990032B1 (en) | 2019-06-25 | 2023-12-06 | Bracco Suisse SA | Freeze-dried composition for preparing calibrated gas-filled microvesicles |
| CN114007656A (zh) * | 2019-06-25 | 2022-02-01 | 博莱科瑞士股份有限公司 | 用于制备标准化充气微泡的冻干组合物 |
| WO2022139583A1 (en) * | 2020-12-27 | 2022-06-30 | Solstice Pharmaceuticals B.V. | A cartridge for mixing a phospholipid composition intended for intracorporeal use |
| NL2027237B1 (en) * | 2020-12-27 | 2022-07-21 | Solstice Pharmaceuticals B V | Process for controlled manufacturing of mono-disperse microbubbles |
| CN114011478B (zh) * | 2021-02-20 | 2023-06-02 | 中国海洋石油集团有限公司 | 一种多功能微流控芯片及其制作方法 |
| WO2023285628A1 (en) | 2021-07-14 | 2023-01-19 | Bracco Suisse Sa | Cationic calibrated-size gas-filled microvesicles |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0751496B2 (ja) * | 1986-04-02 | 1995-06-05 | 武田薬品工業株式会社 | リポソ−ムの製造法 |
| US7083572B2 (en) | 1993-11-30 | 2006-08-01 | Bristol-Myers Squibb Medical Imaging, Inc. | Therapeutic delivery systems |
| ES2192572T3 (es) | 1993-12-15 | 2003-10-16 | Bracco Research Sa | Medios de contraste de ultrasonidos, agentes de contraste que contienen los medios, y metodo. |
| US20020159951A1 (en) * | 1997-05-06 | 2002-10-31 | Unger Evan C. | Novel targeted compositions for diagnostic and therapeutic use |
| DE602004029010D1 (de) | 2003-02-04 | 2010-10-21 | Bracco Suisse Sa | Ultraschall kontrastmittel und verfahren zur erstellung |
| WO2005041897A2 (en) * | 2003-10-31 | 2005-05-12 | Point Biomedical Corporation | Reconstitutable microsphere compositions useful as ultrasonic contrast agents |
| US8567425B2 (en) * | 2009-11-24 | 2013-10-29 | Opko Diagnostics, Llc | Fluid mixing and delivery in microfluidic systems |
| WO2012098937A1 (ja) * | 2011-01-21 | 2012-07-26 | 国立大学法人 神戸大学 | リポソームの製造方法 |
| GB201111082D0 (en) * | 2011-06-29 | 2011-08-10 | Univ Leeds | Bubble generation |
| EP2827979A1 (en) | 2012-03-22 | 2015-01-28 | Universiteit Twente | Apparatus and method for mass producing a monodisperse microbubble agent |
-
2017
- 2017-08-30 CN CN201780052322.2A patent/CN109640951B/zh active Active
- 2017-08-30 IL IL265070A patent/IL265070B/en unknown
- 2017-08-30 AU AU2017317646A patent/AU2017317646B2/en active Active
- 2017-08-30 JP JP2019508185A patent/JP7197465B2/ja active Active
- 2017-08-30 EP EP17758869.6A patent/EP3506882B1/en active Active
- 2017-08-30 CA CA3032062A patent/CA3032062A1/en active Pending
- 2017-08-30 WO PCT/EP2017/071788 patent/WO2018041906A1/en unknown
- 2017-08-30 KR KR1020197008825A patent/KR102474554B1/ko active IP Right Grant
- 2017-08-30 DK DK17758869.6T patent/DK3506882T3/da active
- 2017-08-30 ES ES17758869T patent/ES2908708T3/es active Active
- 2017-08-30 US US16/327,519 patent/US10918605B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| JP7197465B2 (ja) | 2022-12-27 |
| EP3506882B1 (en) | 2022-01-12 |
| CN109640951B (zh) | 2023-08-25 |
| ES2908708T3 (es) | 2022-05-03 |
| WO2018041906A1 (en) | 2018-03-08 |
| US20190175516A1 (en) | 2019-06-13 |
| CA3032062A1 (en) | 2018-03-08 |
| JP2019526551A (ja) | 2019-09-19 |
| AU2017317646A1 (en) | 2019-02-21 |
| IL265070B (en) | 2022-09-01 |
| US10918605B2 (en) | 2021-02-16 |
| KR102474554B1 (ko) | 2022-12-06 |
| IL265070A (da) | 2019-04-30 |
| CN109640951A (zh) | 2019-04-16 |
| EP3506882A1 (en) | 2019-07-10 |
| AU2017317646B2 (en) | 2023-07-06 |
| KR20190042681A (ko) | 2019-04-24 |
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