DK350181A - Fremgan&smaade til fremstilling af heterocycliske forbindelser - Google Patents

Fremgan&smaade til fremstilling af heterocycliske forbindelser

Info

Publication number
DK350181A
DK350181A DK350181A DK350181A DK350181A DK 350181 A DK350181 A DK 350181A DK 350181 A DK350181 A DK 350181A DK 350181 A DK350181 A DK 350181A DK 350181 A DK350181 A DK 350181A
Authority
DK
Denmark
Prior art keywords
compounds
alpha
heterocyclic compounds
formula
preparation
Prior art date
Application number
DK350181A
Other languages
English (en)
Other versions
DK154214B (da
DK154214C (da
Inventor
U Seipp
W Vollenberg
B Muellner
G Michel
Original Assignee
Gruenenthal
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gruenenthal filed Critical Gruenenthal
Publication of DK350181A publication Critical patent/DK350181A/da
Publication of DK154214B publication Critical patent/DK154214B/da
Application granted granted Critical
Publication of DK154214C publication Critical patent/DK154214C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • C07D307/937Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans with hydrocarbon or substituted hydrocarbon radicals directly attached in position 2, e.g. prostacyclins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/54Quaternary phosphonium compounds
    • C07F9/5456Arylalkanephosphonium compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Furan Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Liquid Developers In Electrophotography (AREA)
  • Sheet Holders (AREA)
  • Control Of Positive-Displacement Air Blowers (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK350181A 1980-08-08 1981-08-06 Analogifremgangsmaade til fremstilling af 2-oxabicyclo-(3,3,0)octanderivater DK154214C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3029984A DE3029984C2 (de) 1980-08-08 1980-08-08 2-Oxabicyclo [3.3.0] octanderivate und diese enthaltende Arzneimittel
DE3029984 1980-08-08

Publications (3)

Publication Number Publication Date
DK350181A true DK350181A (da) 1982-02-09
DK154214B DK154214B (da) 1988-10-24
DK154214C DK154214C (da) 1989-03-13

Family

ID=6109130

Family Applications (1)

Application Number Title Priority Date Filing Date
DK350181A DK154214C (da) 1980-08-08 1981-08-06 Analogifremgangsmaade til fremstilling af 2-oxabicyclo-(3,3,0)octanderivater

Country Status (23)

Country Link
US (1) US4372971A (da)
EP (1) EP0045842B1 (da)
JP (1) JPS5754180A (da)
KR (1) KR850000388B1 (da)
AT (1) ATE5884T1 (da)
AU (1) AU542775B2 (da)
CA (1) CA1169871A (da)
DD (1) DD201590A5 (da)
DE (2) DE3029984C2 (da)
DK (1) DK154214C (da)
ES (1) ES504618A0 (da)
FI (1) FI72973C (da)
GR (1) GR75238B (da)
HK (1) HK26187A (da)
HU (1) HU184870B (da)
IE (1) IE51308B1 (da)
IL (1) IL63322A (da)
MY (1) MY8600649A (da)
NO (1) NO154166C (da)
PT (1) PT73406B (da)
SU (1) SU1072801A3 (da)
YU (1) YU42416B (da)
ZA (1) ZA814720B (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL65387A0 (en) * 1981-04-14 1982-05-31 Chinoin Gyogyszer Es Vegyeszet 2,3,4-trinor-m-inter-phenylene-prostaglandin derivatives and a process for the preparation thereof
IL67332A (en) * 1981-12-01 1985-12-31 Chinoin Gyogyszer Es Vegyeszet Inter-m-phenylene-prostacyclin analogues,process for the preparation thereof and pharmaceutical compositions containing them
HU188559B (en) * 1981-12-01 1986-04-28 Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt,Hu Process for preparing new inter-m-phenylene-prostacyclin derivatives
HU190007B (en) * 1982-05-06 1986-08-28 Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt,Hu Process for producing new aromatic prostacylin analogues
DE3317159A1 (de) * 1982-05-27 1983-12-01 Grünenthal GmbH, 5190 Stolberg Verfahren zur herstellung von 5z-formen von 2,3,4-trinor-1,5-inter-m-phenylen- prostacyclinderivaten
DE3914735A1 (de) * 1989-05-05 1990-11-08 Gruenenthal Gmbh Pharmakologisch wirksame ester, diese enthaltende arzneimittel und die herstellung dieser ester und arzneimittel

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3933898A (en) * 1972-10-30 1976-01-20 The Upjohn Company PGE1 -oxa phenylene compounds
US3933900A (en) * 1972-10-30 1976-01-20 The Upjohn Company PGEo oxa-phenylene compounds
US3933897A (en) * 1972-10-30 1976-01-20 The Upjohn Company PGA1 -oxa-phenylene compounds
US3933895A (en) * 1972-10-30 1976-01-20 The Upjohn Company Oxa-phenylene compounds
US3933899A (en) * 1972-10-30 1976-01-20 The Upjohn Company PGE2 -oxa-phenylene compounds
US3933896A (en) * 1972-10-30 1976-01-20 The Upjohn Company PGF1.sub.β -oxa phenylene compounds
DE2346706A1 (de) * 1973-09-17 1975-04-03 Hoechst Ag Neue, nicht natuerlich vorkommende analoga von prostansaeuren und verfahren zu ihrer herstellung
IL51189A (en) * 1976-02-04 1985-08-30 Upjohn Co Prostaglandin analogs
US4238623A (en) * 1976-03-29 1980-12-09 Miles Laboratories, Inc. 5,6-Benzo analogues of prostaglandin
AU524786B2 (en) * 1977-03-07 1982-10-07 The Upjohn Company Prostacyclins
US4100192A (en) * 1977-04-18 1978-07-11 The Upjohn Company Inter-phenylene-PG amides
US4207257A (en) * 1977-04-18 1980-06-10 The Upjohn Company Inter-phenylene-13,14-dihydro-PG amides
IT1088036B (it) * 1977-11-25 1985-06-04 Erba Carlo Spa 15-epi-prostaciclina e prostaciclina analoghi
IT1099575B (it) 1978-07-20 1985-09-18 Erba Carlo Spa 20-metil-13,14-deidro-pgi2' suoi sali e suoi 16s- e 16r-metil derivati
US4180657A (en) * 1978-08-14 1979-12-25 The Upjohn Company Acyl-substituted phenyl esters of prostacyclin-type compounds
US4312810A (en) 1978-11-22 1982-01-26 The Upjohn Company 2,5-Inter-o-phenylene-3,4-dinor-5,9α-epoxy-9-deoxy-PGF1 compounds
DE2902809A1 (de) * 1979-01-25 1980-08-07 Hoechst Ag Neue analoga von prostacyclin

Also Published As

Publication number Publication date
ATE5884T1 (de) 1984-02-15
NO154166B (no) 1986-04-21
DE3029984A1 (de) 1982-02-18
NO812338L (no) 1982-02-09
ES8301957A1 (es) 1983-01-01
SU1072801A3 (ru) 1984-02-07
HK26187A (en) 1987-04-10
FI72973C (fi) 1987-08-10
DK154214B (da) 1988-10-24
ZA814720B (en) 1982-07-28
DE3029984C2 (de) 1983-12-15
ES504618A0 (es) 1983-01-01
PT73406A (fr) 1981-08-01
DD201590A5 (de) 1983-07-27
US4372971A (en) 1983-02-08
YU179081A (en) 1983-06-30
GR75238B (da) 1984-07-13
EP0045842B1 (de) 1984-01-18
EP0045842A1 (de) 1982-02-17
FI812452L (fi) 1982-02-09
KR830006265A (ko) 1983-09-20
KR850000388B1 (ko) 1985-03-25
JPS5754180A (en) 1982-03-31
CA1169871A (en) 1984-06-26
PT73406B (fr) 1982-08-09
HU184870B (en) 1984-10-29
IE811357L (en) 1982-02-08
MY8600649A (en) 1986-12-31
IL63322A (en) 1985-01-31
DE3161958D1 (en) 1984-02-23
JPS6116393B2 (da) 1986-04-30
AU7246381A (en) 1982-02-11
YU42416B (en) 1988-08-31
IL63322A0 (en) 1981-10-30
AU542775B2 (en) 1985-03-14
IE51308B1 (en) 1986-11-26
FI72973B (fi) 1987-04-30
NO154166C (no) 1986-07-30
DK154214C (da) 1989-03-13

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Legal Events

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PBP Patent lapsed