DK3484853T3 - Fremgangsmåde til fremstilling af en polymorf form af 3-[5-amino-4-(3-cyanobenzoyl)-pyrazol-1-yl]-n-cyclopropyl-4-methylbenzamid - Google Patents
Fremgangsmåde til fremstilling af en polymorf form af 3-[5-amino-4-(3-cyanobenzoyl)-pyrazol-1-yl]-n-cyclopropyl-4-methylbenzamid Download PDFInfo
- Publication number
- DK3484853T3 DK3484853T3 DK17742277.1T DK17742277T DK3484853T3 DK 3484853 T3 DK3484853 T3 DK 3484853T3 DK 17742277 T DK17742277 T DK 17742277T DK 3484853 T3 DK3484853 T3 DK 3484853T3
- Authority
- DK
- Denmark
- Prior art keywords
- cyanobenzoyl
- methylbenzamide
- pyrazol
- cyclopropyl
- amino
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/38—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1612238.4A GB201612238D0 (en) | 2016-07-14 | 2016-07-14 | Method for producing a polymorphic form of 3-[5-amino-4-(3-cyanobenzoyl)-pyrazol-1-Yl]-n-cyclopropyl-4-methylbenzamide |
| PCT/GB2017/052055 WO2018011578A1 (en) | 2016-07-14 | 2017-07-13 | Method for producing a polymorphic form of 3-[5-amino-4-(3-cyanobenzoyl)-pyrazol-1-yl]-n-cyclopropyl-4-methylbenzamide |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK3484853T3 true DK3484853T3 (da) | 2021-05-25 |
| DK3484853T5 DK3484853T5 (da) | 2021-09-06 |
Family
ID=56890595
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK17742277.1T DK3484853T5 (da) | 2016-07-14 | 2017-07-13 | Fremgangsmåde til fremstilling af en polymorf form af 3-[5-amino-4-(3-cyanobenzoyl)-pyrazol-1-yl]-n-cyclopropyl-4-methylbenzamid |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US10995071B2 (da) |
| EP (1) | EP3484853B9 (da) |
| JP (1) | JP7094020B2 (da) |
| KR (1) | KR102460533B1 (da) |
| CN (1) | CN109415325B (da) |
| AU (1) | AU2017294642B2 (da) |
| BR (1) | BR112019000540A2 (da) |
| CA (1) | CA3030617C (da) |
| DK (1) | DK3484853T5 (da) |
| ES (1) | ES2879608T3 (da) |
| GB (1) | GB201612238D0 (da) |
| HU (1) | HUE054686T2 (da) |
| IL (1) | IL263900B (da) |
| MX (1) | MX2019000384A (da) |
| PL (1) | PL3484853T3 (da) |
| PT (1) | PT3484853T (da) |
| RU (1) | RU2765719C2 (da) |
| SG (1) | SG11201811517SA (da) |
| WO (1) | WO2018011578A1 (da) |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69924480D1 (en) * | 1998-05-05 | 2005-05-04 | Hoffmann La Roche | Pyrazolderivative als p-38 map kinase inhibitoren |
| PT1641764E (pt) | 2003-06-26 | 2011-10-27 | Novartis Ag | Inibidores de p38 quinase a base de heterociclo de 5 elementos |
| PT2827860T (pt) * | 2012-03-20 | 2016-12-20 | Mereo Biopharma 1 Ltd | Utilização de um derivado de pirazole no tratamento de exacerbações agudas da doença pulmonar obstructiva crónica |
| JP6741773B2 (ja) | 2016-03-08 | 2020-08-19 | メレオ バイオファーマ １ リミテッド | 炎症状態の急性増悪の治療のための投与レジメン |
| RU2713203C1 (ru) | 2016-03-08 | 2020-02-04 | Мерео Байофарма 1 Лимитед | Режим дозирования при лечении острых обострений хронической обструктивной болезни легких |
-
2016
- 2016-07-14 GB GBGB1612238.4A patent/GB201612238D0/en not_active Ceased
-
2017
- 2017-07-13 PL PL17742277T patent/PL3484853T3/pl unknown
- 2017-07-13 CA CA3030617A patent/CA3030617C/en active Active
- 2017-07-13 WO PCT/GB2017/052055 patent/WO2018011578A1/en unknown
- 2017-07-13 ES ES17742277T patent/ES2879608T3/es active Active
- 2017-07-13 AU AU2017294642A patent/AU2017294642B2/en active Active
- 2017-07-13 SG SG11201811517SA patent/SG11201811517SA/en unknown
- 2017-07-13 EP EP17742277.1A patent/EP3484853B9/en active Active
- 2017-07-13 BR BR112019000540-4A patent/BR112019000540A2/pt active Search and Examination
- 2017-07-13 DK DK17742277.1T patent/DK3484853T5/da active
- 2017-07-13 RU RU2019103879A patent/RU2765719C2/ru active
- 2017-07-13 HU HUE17742277A patent/HUE054686T2/hu unknown
- 2017-07-13 KR KR1020197001013A patent/KR102460533B1/ko active IP Right Grant
- 2017-07-13 US US16/317,014 patent/US10995071B2/en active Active
- 2017-07-13 PT PT177422771T patent/PT3484853T/pt unknown
- 2017-07-13 MX MX2019000384A patent/MX2019000384A/es unknown
- 2017-07-13 JP JP2019501449A patent/JP7094020B2/ja active Active
- 2017-07-13 CN CN201780041115.7A patent/CN109415325B/zh active Active
-
2018
- 2018-12-23 IL IL263900A patent/IL263900B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| RU2019103879A3 (da) | 2020-08-14 |
| KR20190027819A (ko) | 2019-03-15 |
| ES2879608T3 (es) | 2021-11-22 |
| EP3484853A1 (en) | 2019-05-22 |
| JP7094020B2 (ja) | 2022-07-01 |
| PL3484853T3 (pl) | 2021-11-02 |
| CA3030617A1 (en) | 2018-01-18 |
| US20190315694A1 (en) | 2019-10-17 |
| AU2017294642A1 (en) | 2019-01-17 |
| WO2018011578A1 (en) | 2018-01-18 |
| AU2017294642B2 (en) | 2021-03-04 |
| US10995071B2 (en) | 2021-05-04 |
| IL263900A (en) | 2019-01-31 |
| CN109415325A (zh) | 2019-03-01 |
| HUE054686T2 (hu) | 2021-09-28 |
| CN109415325B (zh) | 2022-04-01 |
| KR102460533B1 (ko) | 2022-10-31 |
| EP3484853B1 (en) | 2021-04-21 |
| JP2019521133A (ja) | 2019-07-25 |
| SG11201811517SA (en) | 2019-01-30 |
| CA3030617C (en) | 2024-02-20 |
| RU2765719C2 (ru) | 2022-02-02 |
| PT3484853T (pt) | 2021-05-25 |
| MX2019000384A (es) | 2019-05-23 |
| DK3484853T5 (da) | 2021-09-06 |
| EP3484853B9 (en) | 2021-07-28 |
| GB201612238D0 (en) | 2016-08-31 |
| RU2019103879A (ru) | 2020-08-14 |
| BR112019000540A2 (pt) | 2019-04-24 |
| IL263900B (en) | 2022-04-01 |
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