DK3468964T3 - Modulatorer af SOCE, sammensætninger og anvendelser deraf - Google Patents

Modulatorer af SOCE, sammensætninger og anvendelser deraf Download PDF

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Publication number
DK3468964T3
DK3468964T3 DK17732232.8T DK17732232T DK3468964T3 DK 3468964 T3 DK3468964 T3 DK 3468964T3 DK 17732232 T DK17732232 T DK 17732232T DK 3468964 T3 DK3468964 T3 DK 3468964T3
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DK
Denmark
Prior art keywords
soce
modulators
compositions
Prior art date
Application number
DK17732232.8T
Other languages
English (en)
Inventor
Tracey Pirali
Armando A Genazzani
Beatrice Riva
Original Assignee
Universita Degli Studi Del Piemonte Orientale Amedeo Avogadro
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Application filed by Universita Degli Studi Del Piemonte Orientale Amedeo Avogadro filed Critical Universita Degli Studi Del Piemonte Orientale Amedeo Avogadro
Application granted granted Critical
Publication of DK3468964T3 publication Critical patent/DK3468964T3/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Inductance-Capacitance Distribution Constants And Capacitance-Resistance Oscillators (AREA)
DK17732232.8T 2016-06-08 2017-06-07 Modulatorer af SOCE, sammensætninger og anvendelser deraf DK3468964T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITUA2016A004199A ITUA20164199A1 (it) 2016-06-08 2016-06-08 Modulatori di soce compisizioni e relativi usi
PCT/IB2017/053355 WO2017212414A1 (en) 2016-06-08 2017-06-07 Modulators of soce, compositions, and uses thereof

Publications (1)

Publication Number Publication Date
DK3468964T3 true DK3468964T3 (da) 2021-03-15

Family

ID=57113604

Family Applications (1)

Application Number Title Priority Date Filing Date
DK17732232.8T DK3468964T3 (da) 2016-06-08 2017-06-07 Modulatorer af SOCE, sammensætninger og anvendelser deraf

Country Status (7)

Country Link
US (1) US10519138B2 (da)
EP (1) EP3468964B1 (da)
DK (1) DK3468964T3 (da)
ES (1) ES2861317T3 (da)
IT (1) ITUA20164199A1 (da)
PL (1) PL3468964T3 (da)
WO (1) WO2017212414A1 (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2019340601A1 (en) 2018-09-14 2021-05-13 Rhizen Pharmaceuticals A G Compositions comprising a CRAC inhibitor and a corticosteroid and methods of use thereof
EP3860625A4 (en) * 2018-10-04 2022-08-03 The Trustees of Indiana University METHODS OF TREATING KIDNEY DISORDERS USING CALCIUM CHANNEL INHIBITORS
CN111153817B (zh) * 2020-01-20 2021-02-02 四川大学 苯氧基-n-苯基苯胺衍生物及其应用
IT202000003692A1 (it) * 2020-02-21 2021-08-21 Univ Degli Studi Del Piemonte Orientale Amedeo Avogadro Composti bifenilici come modulatori di soce, loro composizioni e usi
CN111494370B (zh) * 2020-03-30 2021-07-06 中南大学湘雅二医院 Pyr3在制备保护肝损伤的药物中的应用

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20010044445A1 (en) * 1999-04-08 2001-11-22 Bamaung Nwe Y. Azole inhibitors of cytokine production
DE10149370A1 (de) * 2001-10-06 2003-04-10 Merck Patent Gmbh Pyrazolderivate
JPWO2006115140A1 (ja) 2005-04-22 2008-12-18 アステラス製薬株式会社 腸疾患の予防若しくは治療剤
US8039502B2 (en) * 2007-07-24 2011-10-18 The Ohio State University Research Foundation Anti-infective agents against intracellular pathogens
US8389567B2 (en) 2007-12-12 2013-03-05 Calcimedica, Inc. Compounds that modulate intracellular calcium
US20110230536A1 (en) 2008-10-24 2011-09-22 Calcimedica, Inc. Phenylpyrazole inhibitors of store operated calcium release
WO2010122088A1 (en) * 2009-04-24 2010-10-28 Glaxo Group Limited Pyrazole and triazole carboxamides as crac channel inhibitors
UY32571A (es) 2009-04-24 2010-11-30 Glaxo Group Ltd Compuestos derivados de pirazol amida
US8377970B2 (en) * 2009-10-08 2013-02-19 Rhizen Pharmaceuticals Sa Modulators of calcium release-activated calcium channel
US8993612B2 (en) 2009-10-08 2015-03-31 Rhizen Pharmaceuticals Sa Modulators of calcium release-activated calcium channel and methods for treatment of non-small cell lung cancer
JP6112486B2 (ja) 2010-04-27 2017-04-12 カルシメディカ,インク. 細胞内カルシウムを調節する化合物
EP2563759B1 (en) 2010-04-27 2022-04-06 Calcimedica, Inc. Compounds that modulate intracellular calcium
WO2013050270A1 (en) 2011-10-05 2013-04-11 F. Hoffmann-La Roche Ag Benzoxazine derivatives as crac modulators
US20130090334A1 (en) 2011-10-05 2013-04-11 Hoffmann-La Roche Inc Azabenzoxazine derivatives as crac modulators
WO2013092444A1 (en) 2011-12-20 2013-06-27 F. Hoffmann-La Roche Ag Diazaindole inhibitors of crac
US20130158066A1 (en) 2011-12-20 2013-06-20 Hoffmann-La Roche Inc. 4-azaindole inhibitors of crac
WO2013092467A1 (en) 2011-12-20 2013-06-27 F. Hoffmann-La Roche Ag 7-azaindole inhibitors of crac
CN105188380B (zh) * 2013-03-15 2017-08-15 百时美施贵宝公司 Lxr调节剂

Also Published As

Publication number Publication date
WO2017212414A1 (en) 2017-12-14
EP3468964A1 (en) 2019-04-17
ITUA20164199A1 (it) 2017-12-08
US10519138B2 (en) 2019-12-31
ES2861317T3 (es) 2021-10-06
PL3468964T3 (pl) 2021-07-12
EP3468964B1 (en) 2020-12-30
US20190300509A1 (en) 2019-10-03

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DK3468964T3 (da) Modulatorer af SOCE, sammensætninger og anvendelser deraf