DK3456359T3 - Sammensætning til neutronindfangningsterapi, der er dannet ved anvendelse af ionimplantation - Google Patents

Sammensætning til neutronindfangningsterapi, der er dannet ved anvendelse af ionimplantation Download PDF

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Publication number
DK3456359T3
DK3456359T3 DK17795341.1T DK17795341T DK3456359T3 DK 3456359 T3 DK3456359 T3 DK 3456359T3 DK 17795341 T DK17795341 T DK 17795341T DK 3456359 T3 DK3456359 T3 DK 3456359T3
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DK
Denmark
Prior art keywords
composition
ion implantation
neutron capture
capture therapy
therapy formed
Prior art date
Application number
DK17795341.1T
Other languages
English (en)
Inventor
Chien-Hsu Chen
Causon Ko-Chuan Jen
Huan Niu
Original Assignee
Huan Niu
Chen Chien Hsu
Jen Causon Ko Chuan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Huan Niu, Chen Chien Hsu, Jen Causon Ko Chuan filed Critical Huan Niu
Application granted granted Critical
Publication of DK3456359T3 publication Critical patent/DK3456359T3/da

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/009Neutron capture therapy, e.g. using uranium or non-boron material
    • A61K41/0095Boron neutron capture therapy, i.e. BNCT, e.g. using boronated porphyrins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/009Neutron capture therapy, e.g. using uranium or non-boron material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6921Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere
    • A61K47/6927Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere the form being a solid microparticle having no hollow or gas-filled cores
    • A61K47/6929Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere the form being a solid microparticle having no hollow or gas-filled cores the form being a nanoparticle, e.g. an immuno-nanoparticle
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Nanotechnology (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Radiation-Therapy Devices (AREA)
  • Medicinal Preparation (AREA)
DK17795341.1T 2016-05-11 2017-03-28 Sammensætning til neutronindfangningsterapi, der er dannet ved anvendelse af ionimplantation DK3456359T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US15/151,510 US10799587B2 (en) 2016-05-11 2016-05-11 Ion implantation of neutron capture elements into nanodiamond particles to form composition for neutron capture therapy usage
PCT/CN2017/078477 WO2017193723A1 (zh) 2016-05-11 2017-03-28 通过离子植入形成用于中子俘获治疗的组成物

Publications (1)

Publication Number Publication Date
DK3456359T3 true DK3456359T3 (da) 2021-03-29

Family

ID=60266345

Family Applications (1)

Application Number Title Priority Date Filing Date
DK17795341.1T DK3456359T3 (da) 2016-05-11 2017-03-28 Sammensætning til neutronindfangningsterapi, der er dannet ved anvendelse af ionimplantation

Country Status (9)

Country Link
US (1) US10799587B2 (da)
EP (1) EP3456359B1 (da)
JP (1) JP6905051B2 (da)
CN (2) CN107362359A (da)
DK (1) DK3456359T3 (da)
ES (1) ES2858924T3 (da)
PL (1) PL3456359T3 (da)
TW (1) TWI629989B (da)
WO (1) WO2017193723A1 (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10582754B2 (en) 2017-03-08 2020-03-10 Toly Management Ltd. Cosmetic container
EP3757137B1 (en) * 2018-02-20 2022-09-07 Tokyo Institute of Technology P-boronophenylalanine derivative and composition containing same, and kit for producing said derivative and composition
US11191836B2 (en) 2018-06-01 2021-12-07 Tae Life Sciences, Llc Biodegradable nanocarrier(s) (BPMOs) for neutron capture therapy and methods thereof
US11219689B2 (en) 2018-10-16 2022-01-11 Tae Life Sciences, Llc Boron enriched linker (“BEL”) compositions for boron neutron capture therapy and methods thereof
US20240065981A1 (en) * 2022-08-23 2024-02-29 San Jose State University Boronated nanoscale substrate and uses thereof

Family Cites Families (19)

* Cited by examiner, † Cited by third party
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KR100190957B1 (ko) * 1995-03-10 1999-06-15 김성년 방사성 키토산 착물, 방사성 키토산 응집입자 및 방사성키토산 착물 제조용 키트, 그리고 그들의 제조방법 및 용도
US6107102A (en) * 1995-06-07 2000-08-22 Regents Of The University Of California Therapeutic microdevices and methods of making and using same
US6458430B1 (en) * 1999-12-22 2002-10-01 Axcelis Technologies, Inc. Pretreatment process for plasma immersion ion implantation
JP3690517B2 (ja) * 2002-02-28 2005-08-31 住友イートンノバ株式会社 イオン注入方法及びイオン注入装置
CN101512770A (zh) * 2006-08-11 2009-08-19 阿克汗技术有限公司 P沟道纳米晶体金刚石场效应晶体管
CN101154476A (zh) 2006-09-26 2008-04-02 王黎 一种放射性示踪剂的生产方法
JP4874751B2 (ja) * 2006-09-27 2012-02-15 株式会社イオンテクノセンター Mr画像法に利用する生体標識用ナノダイヤモンド
JP5168690B2 (ja) * 2007-03-23 2013-03-21 独立行政法人産業技術総合研究所 ホウ素ナノ粒子又はホウ素含有ナノ粒子及びその製造方法
KR100948408B1 (ko) * 2008-02-25 2010-03-19 원광대학교산학협력단 4-(오쏘-카보란-1-일)페놀 유도체, 이의 제조방법 및 이를포함하는 약학적 조성물
CN101284161A (zh) * 2008-05-27 2008-10-15 同济大学 具有放疗和温热疗双重功能的微粒及其制备方法
JP2011178668A (ja) * 2010-02-26 2011-09-15 Osaka Univ Mri造影剤
CN101879427B (zh) 2010-06-29 2013-02-06 南京大学 载有盐酸阿霉素的天然高分子-聚(3-丙烯酰胺基苯硼酸)复合纳米微球及其制法和用途
JP2012206863A (ja) * 2011-03-29 2012-10-25 Shiga Univ Of Medical Science 蛍光ナノダイヤモンド
TWI454281B (zh) * 2011-10-06 2014-10-01 Nat Univ Tsing Hua 硼酸於硼中子捕獲治療肝癌之用途
CN103007306A (zh) * 2012-12-27 2013-04-03 复旦大学 一种钐-153和/或镥-177标记阴阳离子型无机盐纳米材料的方法及其应用
RU2543184C2 (ru) 2013-04-01 2015-02-27 ЗАО "Алмазный Центр" Синтетический радиоактивный наноалмаз и способ его получения
JP6241943B2 (ja) * 2014-03-14 2017-12-06 学校法人東京理科大学 ボロンドープダイヤモンドナノ粒子の製造方法
CN104399094B (zh) * 2014-11-03 2017-02-15 苏州大学附属第一医院 靶向硼制剂及其制备方法
CN104524594B (zh) * 2015-01-06 2017-03-15 山西大学 纳米钻石表面修饰负载甲氨蝶呤的药物及其制备方法

Also Published As

Publication number Publication date
US10799587B2 (en) 2020-10-13
EP3456359B1 (en) 2021-01-20
EP3456359A4 (en) 2019-12-25
US20170326236A1 (en) 2017-11-16
CN118787740A (zh) 2024-10-18
PL3456359T3 (pl) 2021-07-05
JP6905051B2 (ja) 2021-07-21
JP2019515962A (ja) 2019-06-13
ES2858924T3 (es) 2021-09-30
EP3456359A1 (en) 2019-03-20
TWI629989B (zh) 2018-07-21
WO2017193723A1 (zh) 2017-11-16
CN107362359A (zh) 2017-11-21
TW201739460A (zh) 2017-11-16

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