DK3242931T3 - Formuleringer til stabilisering af bakteriecelleekstrakter - Google Patents

Formuleringer til stabilisering af bakteriecelleekstrakter Download PDF

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Publication number
DK3242931T3
DK3242931T3 DK16735454.7T DK16735454T DK3242931T3 DK 3242931 T3 DK3242931 T3 DK 3242931T3 DK 16735454 T DK16735454 T DK 16735454T DK 3242931 T3 DK3242931 T3 DK 3242931T3
Authority
DK
Denmark
Prior art keywords
formulations
cell extracts
bacteria cell
stabilizing
stabilizing bacteria
Prior art date
Application number
DK16735454.7T
Other languages
English (en)
Inventor
Martin Chandler
Kirk Hayenga
Henry Heinsohn
Original Assignee
Sutro Biopharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sutro Biopharma Inc filed Critical Sutro Biopharma Inc
Application granted granted Critical
Publication of DK3242931T3 publication Critical patent/DK3242931T3/da

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/02Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/53Colony-stimulating factor [CSF]
    • C07K14/535Granulocyte CSF; Granulocyte-macrophage CSF
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • C12P1/04Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using bacteria

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Mycology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
DK16735454.7T 2015-01-08 2016-01-08 Formuleringer til stabilisering af bakteriecelleekstrakter DK3242931T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562101266P 2015-01-08 2015-01-08
PCT/US2016/012599 WO2016112258A1 (en) 2015-01-08 2016-01-08 Formulations for drying bacterial cell extracts

Publications (1)

Publication Number Publication Date
DK3242931T3 true DK3242931T3 (da) 2021-05-10

Family

ID=56356455

Family Applications (1)

Application Number Title Priority Date Filing Date
DK16735454.7T DK3242931T3 (da) 2015-01-08 2016-01-08 Formuleringer til stabilisering af bakteriecelleekstrakter

Country Status (4)

Country Link
US (3) US10648010B2 (da)
EP (1) EP3242931B1 (da)
DK (1) DK3242931T3 (da)
WO (1) WO2016112258A1 (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016004024A1 (en) * 2014-07-02 2016-01-07 Sutro Biopharma, Inc. High growth capacity auxotrophic escherichia coli and methods of use
WO2016112258A1 (en) 2015-01-08 2016-07-14 Sutro Biopharma, Inc. Formulations for drying bacterial cell extracts
CN118662649A (zh) 2016-12-30 2024-09-20 Vaxcyte公司 具有非天然氨基酸的多肽-抗原缀合物
US11951165B2 (en) 2016-12-30 2024-04-09 Vaxcyte, Inc. Conjugated vaccine carrier proteins
DK3354737T3 (da) * 2017-01-25 2020-11-09 Fraunhofer Ges Forschung System til cellefri proteinsyntese
CN109321620A (zh) * 2017-07-31 2019-02-12 康码(上海)生物科技有限公司 一种蛋白合成冻干制剂及其制备方法和应用
CN109182129B (zh) * 2018-09-05 2021-03-02 广东海大畜牧兽医研究院有限公司 一种细菌保护剂及其应用
WO2023010053A1 (en) * 2021-07-28 2023-02-02 Northwestern University A low-cost, thermostable, lyophilized, cell-free protein synthesis platform
US20240043895A1 (en) * 2022-08-08 2024-02-08 Sutro Biopharma, Inc. Spray dried extract

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0259739A1 (en) 1986-09-10 1988-03-16 Rhone-Poulenc Inc. Improved stability of freeze-dried cultures
US20020039771A1 (en) 1996-07-16 2002-04-04 Lars-Erik Peters Method for producing complex multienzymatical, storage resistant reaction mixtures and use thereof
AU765632B2 (en) 1999-05-11 2003-09-25 Cellfree Sciences Co., Ltd. Preparation containing cell extract for synthesizing cell-free protein and means for synthesizing cell-free protein
JP2002125693A (ja) * 2000-10-19 2002-05-08 Toyobo Co Ltd 無細胞タンパク質合成用細胞抽出液組成物
US8685392B2 (en) 2009-10-07 2014-04-01 Trustees Of Boston University Rothia species glutamine endopeptidases and use thereof
US9732161B2 (en) * 2012-06-26 2017-08-15 Sutro Biopharma, Inc. Modified Fc proteins comprising site-specific non-natural amino acid residues, conjugates of the same, methods of their preparation and methods of their use
WO2016112258A1 (en) 2015-01-08 2016-07-14 Sutro Biopharma, Inc. Formulations for drying bacterial cell extracts

Also Published As

Publication number Publication date
US20230167475A1 (en) 2023-06-01
EP3242931A1 (en) 2017-11-15
WO2016112258A1 (en) 2016-07-14
US11408021B2 (en) 2022-08-09
EP3242931B1 (en) 2021-03-31
US20180002732A1 (en) 2018-01-04
US12098406B2 (en) 2024-09-24
US10648010B2 (en) 2020-05-12
EP3242931A4 (en) 2018-07-25
US20200299745A1 (en) 2020-09-24

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