DK3416675T3 - Behandling af hepatitis-delta-virusinfektion med interferon lambda - Google Patents

Behandling af hepatitis-delta-virusinfektion med interferon lambda Download PDF

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Publication number
DK3416675T3
DK3416675T3 DK17753966.5T DK17753966T DK3416675T3 DK 3416675 T3 DK3416675 T3 DK 3416675T3 DK 17753966 T DK17753966 T DK 17753966T DK 3416675 T3 DK3416675 T3 DK 3416675T3
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DK
Denmark
Prior art keywords
treatment
virus infection
hepatitis delta
delta virus
interferon lambda
Prior art date
Application number
DK17753966.5T
Other languages
Danish (da)
English (en)
Inventor
Eduardo Bruno Martins
Original Assignee
Eiger Biopharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eiger Biopharmaceuticals Inc filed Critical Eiger Biopharmaceuticals Inc
Application granted granted Critical
Publication of DK3416675T3 publication Critical patent/DK3416675T3/da

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/21Interferons [IFN]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/60Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Communicable Diseases (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK17753966.5T 2016-02-19 2017-02-17 Behandling af hepatitis-delta-virusinfektion med interferon lambda DK3416675T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662297759P 2016-02-19 2016-02-19
PCT/US2017/018466 WO2017143253A1 (en) 2016-02-19 2017-02-17 Treatment of hepatitis delta virus infection with interferon lambda

Publications (1)

Publication Number Publication Date
DK3416675T3 true DK3416675T3 (da) 2021-06-14

Family

ID=59625481

Family Applications (1)

Application Number Title Priority Date Filing Date
DK17753966.5T DK3416675T3 (da) 2016-02-19 2017-02-17 Behandling af hepatitis-delta-virusinfektion med interferon lambda

Country Status (17)

Country Link
US (1) US10953072B2 (enExample)
EP (2) EP3957319B1 (enExample)
JP (3) JP7674628B2 (enExample)
KR (1) KR20180110127A (enExample)
CN (1) CN108883156A (enExample)
CY (1) CY1124220T1 (enExample)
DK (1) DK3416675T3 (enExample)
ES (2) ES3008560T3 (enExample)
HR (1) HRP20210862T1 (enExample)
HU (1) HUE055343T2 (enExample)
LT (1) LT3416675T (enExample)
PL (1) PL3416675T3 (enExample)
PT (1) PT3416675T (enExample)
RS (1) RS61944B1 (enExample)
SI (1) SI3416675T1 (enExample)
SM (1) SMT202100335T1 (enExample)
WO (1) WO2017143253A1 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11311519B2 (en) 2014-05-01 2022-04-26 Eiger Biopharmaceuticals, Inc. Treatment of hepatitis delta virus infection
WO2016172342A1 (en) 2015-04-21 2016-10-27 Eiger Biopharmaceuticals, Inc. Pharmaceutical compositions comprising lonafarnib and ritonavir
ES3008560T3 (en) 2016-02-19 2025-03-24 Eit Pharma Inc Treatment of hepatitis delta virus infection with interferon lambda
GB201621728D0 (en) 2016-12-20 2017-02-01 Ucb Biopharma Sprl Methods
US20210187073A1 (en) * 2018-08-23 2021-06-24 Eiger Biopharmaceuticals, Inc. Treatment of hepatitis delta virus infection with interferon lambda
CA3139291A1 (en) 2019-07-18 2021-01-21 Jacky Vonderscher Method for decreasing adverse-effects of interferon
WO2021034101A1 (ko) * 2019-08-21 2021-02-25 한국과학기술원 신규 인터페론 람다 변이체 및 이의 제조방법
CN114555079A (zh) * 2019-10-16 2022-05-27 艾格尔峰生物制药有限公司 治疗丁型肝炎病毒感染的方法
US20230285510A1 (en) * 2020-02-06 2023-09-14 Eiger Biopharmaceuticals, Inc. Treatment of coronavirus infection with interferon lambda

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4377126B2 (ja) 2000-06-30 2009-12-02 ザイモジェネティクス,インコーポレイティド インターフェロン−様タンパク質zcyto21
US7038032B2 (en) 2001-04-20 2006-05-02 Zymogenetics, Inc. Cytokine protein family
JP2006509041A (ja) 2002-10-23 2006-03-16 ザイモジェネティクス,インコーポレイティド Il−28およびil−29を用いるウイルス感染を治療するための方法
DK1668031T3 (da) 2003-08-07 2008-06-30 Zymogenetics Inc Homogene præparater af IL-29
EP1750749A2 (en) 2004-04-02 2007-02-14 ZymoGenetics, Inc. Il-28 and il-29 cysteine mutants for treating viral infection
JP4987001B2 (ja) 2005-07-20 2012-07-25 ザイモジェネティクス リミテッド ライアビリティ カンパニー 癌および自己免疫障害を処置するためのil28およびil29の短縮型システイン変異体の使用法
EP1912668A2 (en) 2005-07-20 2008-04-23 ZymoGenetics, Inc. Il28 and il29 truncated cysteine mutants and antiviral methods of using same
SI1931704T1 (sl) 2005-10-04 2011-04-29 Zymogenetics L L C Priprava in čiščenje IL-29
JP2010504909A (ja) 2006-09-14 2010-02-18 メドジェニクス・メディカル・イスラエル・リミテッド 長期持続性の医薬製剤
CN105535961A (zh) 2008-04-04 2016-05-04 宾夕法尼亚大学托管会 使用il-28和组合物的疫苗和免疫治疗及其使用方法
WO2011088126A2 (en) * 2010-01-13 2011-07-21 Eiger Biopharmaceuticals, Inc. Treatment of viral infection with prenyltransferase inhibitors
SG10201605265TA (en) * 2011-06-14 2016-08-30 Globeimmune Inc Yeast-Based Compositions and Methods for the Treatment or Prevention of Hepatitis Delta Virus Infection
RU2014111179A (ru) 2011-08-25 2015-09-27 Наноджен Фармасьютикал Байотекнолоджи КОНЪЮГАТЫ ИНТЕРФЕРОНА λ1 И ПОЛИЭТИЛЕНГЛИКОЛЯ
US8454947B1 (en) 2012-03-01 2013-06-04 Nanogen Pharmaceutical Biotechnology PEG-interferon lambda 1 conjugates
WO2014032176A1 (en) 2012-08-30 2014-03-06 Replicor Inc. Methods for the treatment of hepatitis b and hepatitis d infections
CN111329989A (zh) 2012-11-02 2020-06-26 药品循环有限责任公司 Tec家族激酶抑制剂辅助疗法
HUE044606T2 (hu) * 2014-05-01 2019-11-28 Eiger Biopharmaceuticals Inc A hepatitis delta vírusfertõzés kezelése
ES2844629T3 (es) * 2015-11-04 2021-07-22 Eiger Biopharmaceuticals Inc Tratamiento de la infección por el virus de la hepatitis delta
ES3008560T3 (en) 2016-02-19 2025-03-24 Eit Pharma Inc Treatment of hepatitis delta virus infection with interferon lambda
US20210187073A1 (en) 2018-08-23 2021-06-24 Eiger Biopharmaceuticals, Inc. Treatment of hepatitis delta virus infection with interferon lambda

Also Published As

Publication number Publication date
EP3957319A1 (en) 2022-02-23
ES3008560T3 (en) 2025-03-24
KR20180110127A (ko) 2018-10-08
RS61944B1 (sr) 2021-07-30
HRP20210862T1 (hr) 2021-09-17
JP2019505553A (ja) 2019-02-28
EP3416675B1 (en) 2021-03-24
PT3416675T (pt) 2021-06-14
CY1124220T1 (el) 2022-05-27
US20210228686A1 (en) 2021-07-29
JP2022172279A (ja) 2022-11-15
PL3416675T3 (pl) 2021-10-11
LT3416675T (lt) 2021-06-25
HUE055343T2 (hu) 2022-05-28
US20190111110A1 (en) 2019-04-18
SMT202100335T1 (it) 2021-07-12
EP3416675B9 (en) 2021-07-14
JP7674628B2 (ja) 2025-05-12
WO2017143253A1 (en) 2017-08-24
SI3416675T1 (sl) 2021-09-30
CN108883156A (zh) 2018-11-23
JP2024156840A (ja) 2024-11-06
US10953072B2 (en) 2021-03-23
EP3416675A4 (en) 2020-01-08
ES2874592T3 (es) 2021-11-05
EP3416675A1 (en) 2018-12-26
EP3957319B1 (en) 2024-12-04

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