DK3390A - Monoklonalt antistof, som er specifikt for adhaesionsfunktionsdomaenet af et fagocytcelleoverfladeprotein - Google Patents

Monoklonalt antistof, som er specifikt for adhaesionsfunktionsdomaenet af et fagocytcelleoverfladeprotein Download PDF

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Publication number
DK3390A
DK3390A DK003390A DK3390A DK3390A DK 3390 A DK3390 A DK 3390A DK 003390 A DK003390 A DK 003390A DK 3390 A DK3390 A DK 3390A DK 3390 A DK3390 A DK 3390A
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DK
Denmark
Prior art keywords
monoclonal antibody
phagocycle
cell surface
antibody specific
surface protein
Prior art date
Application number
DK003390A
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English (en)
Other versions
DK3390D0 (da
Inventor
Stuart F Schlossman
James D Griffin
Original Assignee
Dana Farber Cancer Inst Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dana Farber Cancer Inst Inc filed Critical Dana Farber Cancer Inst Inc
Publication of DK3390D0 publication Critical patent/DK3390D0/da
Publication of DK3390A publication Critical patent/DK3390A/da

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/78Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2839Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
    • C07K16/2845Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily against integrin beta2-subunit-containing molecules, e.g. CD11, CD18
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827Proteins from mammals or birds
    • Y10S530/828Cancer

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DK003390A 1987-07-06 1990-01-05 Monoklonalt antistof, som er specifikt for adhaesionsfunktionsdomaenet af et fagocytcelleoverfladeprotein DK3390A (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US7025787A 1987-07-06 1987-07-06
US07/165,024 US5019648A (en) 1987-07-06 1988-03-07 Monoclonal antibody specific for the adhesion function domain of a phagocyte cell surface protein
PCT/US1988/001414 WO1989000190A1 (en) 1987-07-06 1988-05-02 Monoclonal antibody specific for the adhesion function domain of a phagocyte cell surface protein

Publications (2)

Publication Number Publication Date
DK3390D0 DK3390D0 (da) 1990-01-05
DK3390A true DK3390A (da) 1990-03-05

Family

ID=26750961

Family Applications (1)

Application Number Title Priority Date Filing Date
DK003390A DK3390A (da) 1987-07-06 1990-01-05 Monoklonalt antistof, som er specifikt for adhaesionsfunktionsdomaenet af et fagocytcelleoverfladeprotein

Country Status (15)

Country Link
US (1) US5019648A (da)
EP (1) EP0357672B1 (da)
JP (1) JPH03501560A (da)
KR (1) KR960009013B1 (da)
CN (1) CN1028114C (da)
AT (1) ATE121130T1 (da)
AU (1) AU616182B2 (da)
CA (1) CA1340015C (da)
DE (1) DE3853588T2 (da)
DK (1) DK3390A (da)
ES (1) ES2013338A6 (da)
IE (1) IE61392B1 (da)
IL (1) IL86676A (da)
MX (1) MX9203245A (da)
WO (1) WO1989000190A1 (da)

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5019648A (en) * 1987-07-06 1991-05-28 Dana-Farber Cancer Institute Monoclonal antibody specific for the adhesion function domain of a phagocyte cell surface protein
US5219997A (en) * 1987-07-06 1993-06-15 Dana-Farber Cancer Institute Monoclonal antibody which inhibits the adhesion functions of the β integrin, CR3
JPH03503600A (ja) * 1988-03-31 1991-08-15 バイオメディカル・システムズ・リミテッド 治療用ネズミモノクローナル抗体
US5272263A (en) * 1989-04-28 1993-12-21 Biogen, Inc. DNA sequences encoding vascular cell adhesion molecules (VCAMS)
US5217870A (en) * 1989-04-28 1993-06-08 Biogen, Inc. Monoclonal antibodies against CDX
GB9115364D0 (en) 1991-07-16 1991-08-28 Wellcome Found Antibody
JP3509860B2 (ja) 1992-05-11 2004-03-22 コルバス・インターナショナル、インコーポレイテッド 新規好中球インヒビター
US5708141A (en) * 1992-05-11 1998-01-13 Corvas International, Inc. Neutrophil inhibitors
DK0642577T3 (da) * 1992-05-22 2004-07-19 Univ Montana State Antistoffer med specificitet for multiple adhæsionsmolekyler
JPH08502956A (ja) * 1992-10-09 1996-04-02 センター、フォー、ブラッド、リサーチ、インコーポレーテッド ICAM‐1及びフィブリノーゲンへの好中球接着を媒介するMac‐1(CD11b/CD18)分子のサブ集団
US7083979B1 (en) * 1994-03-25 2006-08-01 Indiana University Foundation Methods for enhanced retroviral-mediated gene transfer
US5656441A (en) * 1994-04-19 1997-08-12 Trustees Of Boston University Methods for determining cellular adhesion
US5834889A (en) * 1995-09-22 1998-11-10 Gl Displays, Inc. Cold cathode fluorescent display
US6001356A (en) * 1995-09-29 1999-12-14 Rush-Presbyterian-St. Luke's Medical Center Method of inhibiting tissue destruction in autoimmune disease using anti-CD44 antibodies
DE19739879A1 (de) * 1996-09-19 1998-03-26 Zeiss Carl Fa Kippvorrichtung
US6663863B2 (en) 2000-03-17 2003-12-16 Millennium Pharmaceuticals, Inc. Method of inhibiting stenosis and restenosis
US8914114B2 (en) 2000-05-23 2014-12-16 The Feinstein Institute For Medical Research Inhibition of inflammatory cytokine production by cholinergic agonists and vagus nerve stimulation
CA2476896A1 (en) * 2002-02-26 2003-09-04 North Shore-Long Island Jewish Research Institute Inhibition of inflammatory cytokine production by stimulation of brain muscarinic receptors
US10912712B2 (en) 2004-03-25 2021-02-09 The Feinstein Institutes For Medical Research Treatment of bleeding by non-invasive stimulation
WO2005092308A2 (en) 2004-03-25 2005-10-06 The Feinstein Institute For Medical Research Neural tourniquet
US11207518B2 (en) 2004-12-27 2021-12-28 The Feinstein Institutes For Medical Research Treating inflammatory disorders by stimulation of the cholinergic anti-inflammatory pathway
ATE489132T1 (de) 2004-12-27 2010-12-15 The Feinstein Inst Medical Res Behandlung von entzündlichen erkrankungen durch elektrische stimulation des vagus-nervs
WO2009029614A1 (en) * 2007-08-27 2009-03-05 The Feinstein Institute For Medical Research Devices and methods for inhibiting granulocyte activation by neural stimulation
WO2009146030A1 (en) * 2008-03-31 2009-12-03 The Feinstein Institute For Medical Research Methods and systems for reducing inflammation by neuromodulation of t-cell activity
US9662490B2 (en) 2008-03-31 2017-05-30 The Feinstein Institute For Medical Research Methods and systems for reducing inflammation by neuromodulation and administration of an anti-inflammatory drug
EP2355893B1 (en) 2008-11-18 2013-12-25 Setpoint Medical Corporation Devices for optimizing electrode placement for anti-inflamatory stimulation
US9211410B2 (en) 2009-05-01 2015-12-15 Setpoint Medical Corporation Extremely low duty-cycle activation of the cholinergic anti-inflammatory pathway to treat chronic inflammation
US20110054569A1 (en) * 2009-09-01 2011-03-03 Zitnik Ralph J Prescription pad for treatment of inflammatory disorders
US8996116B2 (en) 2009-10-30 2015-03-31 Setpoint Medical Corporation Modulation of the cholinergic anti-inflammatory pathway to treat pain or addiction
AU2010258792B2 (en) 2009-06-09 2015-07-02 Setpoint Medical Corporation Nerve cuff with pocket for leadless stimulator
US9833621B2 (en) 2011-09-23 2017-12-05 Setpoint Medical Corporation Modulation of sirtuins by vagus nerve stimulation
US11051744B2 (en) 2009-11-17 2021-07-06 Setpoint Medical Corporation Closed-loop vagus nerve stimulation
EP3636314B1 (en) 2009-12-23 2021-09-08 Setpoint Medical Corporation Neural stimulation devices and systems for treatment of chronic inflammation
WO2012154865A2 (en) 2011-05-09 2012-11-15 Setpoint Medical Corporation Single-pulse activation of the cholinergic anti-inflammatory pathway to treat chronic inflammation
US9572983B2 (en) 2012-03-26 2017-02-21 Setpoint Medical Corporation Devices and methods for modulation of bone erosion
US11311725B2 (en) 2014-10-24 2022-04-26 Setpoint Medical Corporation Systems and methods for stimulating and/or monitoring loci in the brain to treat inflammation and to enhance vagus nerve stimulation
WO2016126807A1 (en) 2015-02-03 2016-08-11 Setpoint Medical Corporation Apparatus and method for reminding, prompting, or alerting a patient with an implanted stimulator
US10596367B2 (en) 2016-01-13 2020-03-24 Setpoint Medical Corporation Systems and methods for establishing a nerve block
US10314501B2 (en) 2016-01-20 2019-06-11 Setpoint Medical Corporation Implantable microstimulators and inductive charging systems
US11471681B2 (en) 2016-01-20 2022-10-18 Setpoint Medical Corporation Batteryless implantable microstimulators
EP3405107B1 (en) 2016-01-20 2023-04-12 Setpoint Medical Corporation Control of vagal stimulation
US10583304B2 (en) 2016-01-25 2020-03-10 Setpoint Medical Corporation Implantable neurostimulator having power control and thermal regulation and methods of use
ES2952744T3 (es) 2016-12-15 2023-11-03 Nestle Sa Composiciones y procedimientos que modulan los glóbulos blancos o los neutrófilos en un animal de compañía
US11173307B2 (en) 2017-08-14 2021-11-16 Setpoint Medical Corporation Vagus nerve stimulation pre-screening test
US11260229B2 (en) 2018-09-25 2022-03-01 The Feinstein Institutes For Medical Research Methods and apparatuses for reducing bleeding via coordinated trigeminal and vagal nerve stimulation
KR20230012585A (ko) 2020-05-21 2023-01-26 더 파인스타인 인스티튜츠 포 메디칼 리서치 미주 신경 자극을 위한 시스템들 및 방법들

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4840793A (en) * 1987-06-11 1989-06-20 Dana-Farber Cancer Institute Method of reducing tissue damage at an inflammatory site using a monoclonal antibody
US4935234A (en) * 1987-06-11 1990-06-19 Dana-Farber Cancer Institute Method of reducing tissue damage at an inflammatory site using a monoclonal antibody
US5019648A (en) * 1987-07-06 1991-05-28 Dana-Farber Cancer Institute Monoclonal antibody specific for the adhesion function domain of a phagocyte cell surface protein

Also Published As

Publication number Publication date
DE3853588T2 (de) 1995-11-23
IE881357L (en) 1989-01-06
IE61392B1 (en) 1994-11-02
EP0357672A1 (en) 1990-03-14
EP0357672A4 (en) 1990-06-05
ES2013338A6 (es) 1990-05-01
CA1340015C (en) 1998-08-25
AU616182B2 (en) 1991-10-24
WO1989000190A1 (en) 1989-01-12
CN1028114C (zh) 1995-04-05
KR890701734A (ko) 1989-12-21
DE3853588D1 (de) 1995-05-18
US5019648A (en) 1991-05-28
KR960009013B1 (ko) 1996-07-10
IL86676A (en) 1992-06-21
CN1030611A (zh) 1989-01-25
DK3390D0 (da) 1990-01-05
EP0357672B1 (en) 1995-04-12
AU1721888A (en) 1989-01-30
JPH03501560A (ja) 1991-04-11
IL86676A0 (en) 1988-11-30
MX9203245A (es) 1992-07-01
ATE121130T1 (de) 1995-04-15

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