ATE121130T1 - Monoklonaler antikörper, spezifisch gegen den funktionellen adhäsionsbereich des oberflächenproteins einer phagocyten-zelle. - Google Patents
Monoklonaler antikörper, spezifisch gegen den funktionellen adhäsionsbereich des oberflächenproteins einer phagocyten-zelle.Info
- Publication number
- ATE121130T1 ATE121130T1 AT88904354T AT88904354T ATE121130T1 AT E121130 T1 ATE121130 T1 AT E121130T1 AT 88904354 T AT88904354 T AT 88904354T AT 88904354 T AT88904354 T AT 88904354T AT E121130 T1 ATE121130 T1 AT E121130T1
- Authority
- AT
- Austria
- Prior art keywords
- monoclonal antibodies
- surface protein
- adhesion area
- antibodies specifically
- monoclonal antibody
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2839—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
- C07K16/2845—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily against integrin beta2-subunit-containing molecules, e.g. CD11, CD18
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/827—Proteins from mammals or birds
- Y10S530/828—Cancer
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US7025787A | 1987-07-06 | 1987-07-06 | |
US07/165,024 US5019648A (en) | 1987-07-06 | 1988-03-07 | Monoclonal antibody specific for the adhesion function domain of a phagocyte cell surface protein |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE121130T1 true ATE121130T1 (de) | 1995-04-15 |
Family
ID=26750961
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT88904354T ATE121130T1 (de) | 1987-07-06 | 1988-05-02 | Monoklonaler antikörper, spezifisch gegen den funktionellen adhäsionsbereich des oberflächenproteins einer phagocyten-zelle. |
Country Status (15)
Country | Link |
---|---|
US (1) | US5019648A (de) |
EP (1) | EP0357672B1 (de) |
JP (1) | JPH03501560A (de) |
KR (1) | KR960009013B1 (de) |
CN (1) | CN1028114C (de) |
AT (1) | ATE121130T1 (de) |
AU (1) | AU616182B2 (de) |
CA (1) | CA1340015C (de) |
DE (1) | DE3853588T2 (de) |
DK (1) | DK3390A (de) |
ES (1) | ES2013338A6 (de) |
IE (1) | IE61392B1 (de) |
IL (1) | IL86676A (de) |
MX (1) | MX9203245A (de) |
WO (1) | WO1989000190A1 (de) |
Families Citing this family (46)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5019648A (en) * | 1987-07-06 | 1991-05-28 | Dana-Farber Cancer Institute | Monoclonal antibody specific for the adhesion function domain of a phagocyte cell surface protein |
US5219997A (en) * | 1987-07-06 | 1993-06-15 | Dana-Farber Cancer Institute | Monoclonal antibody which inhibits the adhesion functions of the β integrin, CR3 |
JPH03503600A (ja) * | 1988-03-31 | 1991-08-15 | バイオメディカル・システムズ・リミテッド | 治療用ネズミモノクローナル抗体 |
US5217870A (en) * | 1989-04-28 | 1993-06-08 | Biogen, Inc. | Monoclonal antibodies against CDX |
US5272263A (en) * | 1989-04-28 | 1993-12-21 | Biogen, Inc. | DNA sequences encoding vascular cell adhesion molecules (VCAMS) |
GB9115364D0 (en) * | 1991-07-16 | 1991-08-28 | Wellcome Found | Antibody |
US5708141A (en) * | 1992-05-11 | 1998-01-13 | Corvas International, Inc. | Neutrophil inhibitors |
ATE207498T1 (de) | 1992-05-11 | 2001-11-15 | Corvas Int Inc | Neutrophilen inhibitoren aus nematoden |
PT642577E (pt) * | 1992-05-22 | 2004-08-31 | Univ Montana State | Anticorpos com especificidade para moleculas de adesao multipla |
CA2144738A1 (en) * | 1992-10-09 | 1994-04-28 | Michael Diamond | A subpopulation of mac-1 (cd11b/cd18) molecules which mediate neutrophil adhesion to icam-1 and fibrinogen |
US7083979B1 (en) * | 1994-03-25 | 2006-08-01 | Indiana University Foundation | Methods for enhanced retroviral-mediated gene transfer |
US5656441A (en) * | 1994-04-19 | 1997-08-12 | Trustees Of Boston University | Methods for determining cellular adhesion |
US5834889A (en) * | 1995-09-22 | 1998-11-10 | Gl Displays, Inc. | Cold cathode fluorescent display |
US6001356A (en) * | 1995-09-29 | 1999-12-14 | Rush-Presbyterian-St. Luke's Medical Center | Method of inhibiting tissue destruction in autoimmune disease using anti-CD44 antibodies |
DE19739879A1 (de) * | 1996-09-19 | 1998-03-26 | Zeiss Carl Fa | Kippvorrichtung |
WO2001070266A2 (en) | 2000-03-17 | 2001-09-27 | Millennium Pharmaceuticals, Inc. | Method of inhibiting stenosis and restenosis with a mixture of antibodies anti cd18 and anti ccr2 |
US8914114B2 (en) | 2000-05-23 | 2014-12-16 | The Feinstein Institute For Medical Research | Inhibition of inflammatory cytokine production by cholinergic agonists and vagus nerve stimulation |
EP1487494A2 (de) * | 2002-02-26 | 2004-12-22 | North Shore-Long Island Jewish Research Institute | Hemmung der produktion von entzündungszytokinen durch stimulierung von muskarinischen rezeptoren im gehirn |
US10912712B2 (en) | 2004-03-25 | 2021-02-09 | The Feinstein Institutes For Medical Research | Treatment of bleeding by non-invasive stimulation |
AU2005225458B2 (en) | 2004-03-25 | 2008-12-04 | The Feinstein Institutes For Medical Research | Neural tourniquet |
CN101124012B (zh) | 2004-12-27 | 2012-09-05 | 范因斯坦医学研究院 | 通过电刺激迷走神经治疗炎症性疾病的装置 |
US11207518B2 (en) | 2004-12-27 | 2021-12-28 | The Feinstein Institutes For Medical Research | Treating inflammatory disorders by stimulation of the cholinergic anti-inflammatory pathway |
WO2009029614A1 (en) * | 2007-08-27 | 2009-03-05 | The Feinstein Institute For Medical Research | Devices and methods for inhibiting granulocyte activation by neural stimulation |
US9662490B2 (en) | 2008-03-31 | 2017-05-30 | The Feinstein Institute For Medical Research | Methods and systems for reducing inflammation by neuromodulation and administration of an anti-inflammatory drug |
WO2009146030A1 (en) * | 2008-03-31 | 2009-12-03 | The Feinstein Institute For Medical Research | Methods and systems for reducing inflammation by neuromodulation of t-cell activity |
WO2010059617A2 (en) | 2008-11-18 | 2010-05-27 | Setpoint Medical Corporation | Devices and methods for optimizing electrode placement for anti-inflamatory stimulation |
US9211410B2 (en) | 2009-05-01 | 2015-12-15 | Setpoint Medical Corporation | Extremely low duty-cycle activation of the cholinergic anti-inflammatory pathway to treat chronic inflammation |
US20110054569A1 (en) * | 2009-09-01 | 2011-03-03 | Zitnik Ralph J | Prescription pad for treatment of inflammatory disorders |
US8996116B2 (en) | 2009-10-30 | 2015-03-31 | Setpoint Medical Corporation | Modulation of the cholinergic anti-inflammatory pathway to treat pain or addiction |
US8886339B2 (en) | 2009-06-09 | 2014-11-11 | Setpoint Medical Corporation | Nerve cuff with pocket for leadless stimulator |
US9833621B2 (en) | 2011-09-23 | 2017-12-05 | Setpoint Medical Corporation | Modulation of sirtuins by vagus nerve stimulation |
WO2014169145A1 (en) | 2013-04-10 | 2014-10-16 | Setpoint Medical Corporation | Closed-loop vagus nerve stimulation |
AU2010336337B2 (en) | 2009-12-23 | 2016-02-04 | Setpoint Medical Corporation | Neural stimulation devices and systems for treatment of chronic inflammation |
WO2012154865A2 (en) | 2011-05-09 | 2012-11-15 | Setpoint Medical Corporation | Single-pulse activation of the cholinergic anti-inflammatory pathway to treat chronic inflammation |
US9572983B2 (en) | 2012-03-26 | 2017-02-21 | Setpoint Medical Corporation | Devices and methods for modulation of bone erosion |
US11311725B2 (en) | 2014-10-24 | 2022-04-26 | Setpoint Medical Corporation | Systems and methods for stimulating and/or monitoring loci in the brain to treat inflammation and to enhance vagus nerve stimulation |
US11406833B2 (en) | 2015-02-03 | 2022-08-09 | Setpoint Medical Corporation | Apparatus and method for reminding, prompting, or alerting a patient with an implanted stimulator |
US10596367B2 (en) | 2016-01-13 | 2020-03-24 | Setpoint Medical Corporation | Systems and methods for establishing a nerve block |
WO2017127756A1 (en) | 2016-01-20 | 2017-07-27 | Setpoint Medical Corporation | Control of vagal stimulation |
WO2017127758A1 (en) | 2016-01-20 | 2017-07-27 | Setpoint Medical Corporation | Implantable microstimulators and inductive charging systems |
US11471681B2 (en) | 2016-01-20 | 2022-10-18 | Setpoint Medical Corporation | Batteryless implantable microstimulators |
US10583304B2 (en) | 2016-01-25 | 2020-03-10 | Setpoint Medical Corporation | Implantable neurostimulator having power control and thermal regulation and methods of use |
US11291680B2 (en) | 2016-12-15 | 2022-04-05 | Société des Produits Nestlé S.A. | Compositions and methods that modulate white blood cells or neutrophils in a companion animal |
EP3668402A4 (de) | 2017-08-14 | 2021-05-19 | Setpoint Medical Corporation | Vagusnervstimulationsvorscreening-test |
US11260229B2 (en) | 2018-09-25 | 2022-03-01 | The Feinstein Institutes For Medical Research | Methods and apparatuses for reducing bleeding via coordinated trigeminal and vagal nerve stimulation |
KR20230012585A (ko) | 2020-05-21 | 2023-01-26 | 더 파인스타인 인스티튜츠 포 메디칼 리서치 | 미주 신경 자극을 위한 시스템들 및 방법들 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4935234A (en) * | 1987-06-11 | 1990-06-19 | Dana-Farber Cancer Institute | Method of reducing tissue damage at an inflammatory site using a monoclonal antibody |
US4840793A (en) * | 1987-06-11 | 1989-06-20 | Dana-Farber Cancer Institute | Method of reducing tissue damage at an inflammatory site using a monoclonal antibody |
US5019648A (en) * | 1987-07-06 | 1991-05-28 | Dana-Farber Cancer Institute | Monoclonal antibody specific for the adhesion function domain of a phagocyte cell surface protein |
-
1988
- 1988-03-07 US US07/165,024 patent/US5019648A/en not_active Expired - Lifetime
- 1988-05-02 DE DE3853588T patent/DE3853588T2/de not_active Expired - Fee Related
- 1988-05-02 AU AU17218/88A patent/AU616182B2/en not_active Ceased
- 1988-05-02 AT AT88904354T patent/ATE121130T1/de not_active IP Right Cessation
- 1988-05-02 EP EP88904354A patent/EP0357672B1/de not_active Expired - Lifetime
- 1988-05-02 KR KR1019890700406A patent/KR960009013B1/ko not_active IP Right Cessation
- 1988-05-02 WO PCT/US1988/001414 patent/WO1989000190A1/en active IP Right Grant
- 1988-05-02 JP JP63504165A patent/JPH03501560A/ja active Pending
- 1988-05-05 IE IE135788A patent/IE61392B1/en not_active IP Right Cessation
- 1988-06-09 IL IL86676A patent/IL86676A/xx not_active IP Right Cessation
- 1988-07-04 CN CN88104150A patent/CN1028114C/zh not_active Expired - Fee Related
- 1988-07-05 ES ES8802114A patent/ES2013338A6/es not_active Expired - Lifetime
- 1988-08-25 CA CA000566852A patent/CA1340015C/en not_active Expired - Fee Related
-
1990
- 1990-01-05 DK DK003390A patent/DK3390A/da not_active Application Discontinuation
-
1992
- 1992-06-24 MX MX9203245A patent/MX9203245A/es unknown
Also Published As
Publication number | Publication date |
---|---|
EP0357672B1 (de) | 1995-04-12 |
US5019648A (en) | 1991-05-28 |
IE61392B1 (en) | 1994-11-02 |
DK3390D0 (da) | 1990-01-05 |
ES2013338A6 (es) | 1990-05-01 |
CN1030611A (zh) | 1989-01-25 |
DE3853588T2 (de) | 1995-11-23 |
IL86676A0 (en) | 1988-11-30 |
MX9203245A (es) | 1992-07-01 |
CA1340015C (en) | 1998-08-25 |
EP0357672A1 (de) | 1990-03-14 |
AU1721888A (en) | 1989-01-30 |
AU616182B2 (en) | 1991-10-24 |
IE881357L (en) | 1989-01-06 |
KR960009013B1 (ko) | 1996-07-10 |
JPH03501560A (ja) | 1991-04-11 |
DK3390A (da) | 1990-03-05 |
WO1989000190A1 (en) | 1989-01-12 |
KR890701734A (ko) | 1989-12-21 |
CN1028114C (zh) | 1995-04-05 |
EP0357672A4 (de) | 1990-06-05 |
IL86676A (en) | 1992-06-21 |
DE3853588D1 (de) | 1995-05-18 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification | ||
REN | Ceased due to non-payment of the annual fee |